| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| X C Tang, P De Sarno, K Sugaya, E Giacobin. Effect of huperzine A, a new cholinesterase inhibitor, on the central cholinergic system of the rat. Journal of neuroscience research. vol 24. issue 2. 1989-12-28. PMID:2585551. |
the present study represents the first comprehensive investigation of the effect of huperzine a (hup-a), a new cholinesterase inhibitor (chei) isolated from a lycopodium species, upon acetylcholinesterase (ache) activity, acetylcholine (ach) levels and release, and cholinergic receptors in rat brain following acute i.m. |
1989-12-28 |
2023-08-11 |
mouse |
| A C Santucci, P D Kanof, V Haroutunia. Infusion of NMDA into the nucleus basalis of Meynert, frontal cortex or lateral ventricle in rats: effect on memory and cholinergic brain neurochemistry. Pharmacology, biochemistry, and behavior. vol 33. issue 2. 1989-12-19. PMID:2682674. |
specifically, it was of interest to evaluate the effects of n-methyl-d-aspartic acid-induced lesions of discrete frontal cortical loci on passive avoidance memory and on cortical cholinergic neurochemical markers (choline acetyltransferase--cat and acetylcholinesterase--ache). |
1989-12-19 |
2023-08-11 |
human |
| V L Dawson, F H Gage, M A Hunt, J K Wamsle. Normalization of subtype-specific muscarinic receptor binding in the denervated hippocampus by septodiagonal band grafts. Experimental neurology. vol 106. issue 2. 1989-12-12. PMID:2806454. |
lesion of the fimbria-fornix resulted in a reduction of cholinergic input to the hippocampal formation as indicated by the loss of acetylcholinesterase (ache)-positive staining in all ipsilateral hippocampal laminae and a loss of [3h]hemicholinium-3 binding to cholinergic terminals in the strata oriens (82% reduction) and radiatum (77% reduction) of areas ca2 and ca3 and in the molecular layer of the dentate gyrus (83% reduction). |
1989-12-12 |
2023-08-11 |
rat |
| A J Gower, D Rousseau, P Jamsin, J Gobert, I Hanin, E Wülfer. Behavioural and histological effects of low concentrations of intraventricular AF64A. European journal of pharmacology. vol 166. issue 2. 1989-11-06. PMID:2792193. |
biochemical efficacy of the lesions in terms of cholinergic changes was confirmed by analysis of acetylcholinesterase (ache) levels showing decreases in the hippocampus and the cortex; no studies were carried out with respect to other neurotransmitters. |
1989-11-06 |
2023-08-11 |
rat |
| J A Vega Alvarez, A Martínez Tellería, C Coalla, M E Bengoechea, A Pérez Casa. [Cholinergic innervation of the prostate in the white rat (Rattus norvegicus)]. Archivos espanoles de urologia. vol 42. issue 4. 1989-10-17. PMID:2782953. |
we studied the cholinergic innervation of the prostate in male albino rats using a technic for demonstrating acetylcholinesterase (ache) activity. |
1989-10-17 |
2023-08-11 |
rat |
| G Yang, T J Millar, I G Morga. Co-lamination of cholinergic amacrine cell and displaced ganglion cell dendrites in the chicken retina. Neuroscience letters. vol 103. issue 2. 1989-10-12. PMID:2475831. |
counter-staining for acetylcholinesterase (ache) activity showed that the dendrites of the displaced ganglion cells and the type i cholinergic amacrine cells co-laminated in the outer part of the inner plexiform layer. |
1989-10-12 |
2023-08-11 |
chicken |
| J Clos, S Ghandour, R Eberhart, G Vincendon, G Gombo. The cholinergic system in developing cerebellum: comparative study of normal, hypothyroid and underfed rats. Developmental neuroscience. vol 11. issue 3. 1989-10-06. PMID:2766963. |
when compared with structural findings in the literature, the results provide the following information on the normal and abnormal developing cholinergic system, related or not to cerebellar neurotransmission (1) ache activity, unlike chat, can be considered as a good marker of the developing cholinergic archicerebellum. |
1989-10-06 |
2023-08-11 |
rat |
| M Schinstine, C J Cornbrook. Effect of nerve growth factor on the elongation of neurites from axotomized rat embryonic septal-basal forebrain neurons: an in vitro analysis. Journal of neuroscience research. vol 23. issue 4. 1989-10-03. PMID:2549266. |
acetylcholinesterase (ache) histochemistry was used to assess the effects of ngf on cholinergic neurites. |
1989-10-03 |
2023-08-11 |
rat |
| S Kreissl, G Bicke. Histochemistry of acetylcholinesterase and immunocytochemistry of an acetylcholine receptor-like antigen in the brain of the honeybee. The Journal of comparative neurology. vol 286. issue 1. 1989-10-03. PMID:2768558. |
a histochemical staining method for acetylcholinesterase (ache) and an antiserum raised against nicotinic acetylcholine receptors (achr) of locust nervous tissue were applied in order to reveal certain candidates of cholinergic pathways in the brain of the honeybee. |
1989-10-03 |
2023-08-11 |
bee |
| S Kreissl, G Bicke. Histochemistry of acetylcholinesterase and immunocytochemistry of an acetylcholine receptor-like antigen in the brain of the honeybee. The Journal of comparative neurology. vol 286. issue 1. 1989-10-03. PMID:2768558. |
a particularly striking overlap of achr immunoreactivity and ache staining was found in the lip neuropile of the mushroom bodies, which would suggest a cholinergic input into this neuropile via fibers of the median antennoglomerular tract. |
1989-10-03 |
2023-08-11 |
bee |
| G R Babu, G R Reddy, C S Chett. Benthiocarb toxicity on rat brain AChE. Biochemistry international. vol 19. issue 1. 1989-09-29. PMID:2775302. |
benthiocarb effect on rat brain acetylcholinesterase (ache) has been studied to know the toxic effects of benthiocarb on mammalian cholinergic systems. |
1989-09-29 |
2023-08-11 |
rat |
| R W Russell, R A Booth, C A Smith, D J Jenden, M Roch, K M Rice, S D Lauret. Roles of neurotransmitter receptors in behavior: recovery of function following decreases in muscarinic receptor density induced by cholinesterase inhibition. Behavioral neuroscience. vol 103. issue 4. 1989-09-27. PMID:2765189. |
cholinergic neurotransmitter levels were elevated in rat brain by reducing its inactivating enzyme, acetylcholinesterase (ache), with an anti-ache agent. |
1989-09-27 |
2023-08-11 |
rat |
| E J Mufson, M Bothwell, L B Hersh, J H Kordowe. Nerve growth factor receptor immunoreactive profiles in the normal, aged human basal forebrain: colocalization with cholinergic neurons. The Journal of comparative neurology. vol 285. issue 2. 1989-09-15. PMID:2547849. |
virtually all (greater than 95%) ngf receptor-containing neurons colocalize with the specific cholinergic marker choline acetyltransferase (chat) or the nonspecific marker acetylcholinesterase (ache). |
1989-09-15 |
2023-08-11 |
human |
| J Yoshinaga, T Sasaki, H Ideshita, A Hikiji, T Kuwak. [Acetylcholinesterase activity in CSF in senile dementia of Alzheimer type, vascular dementia, and Parkinson's disease]. Rinsho shinkeigaku = Clinical neurology. vol 29. issue 3. 1989-08-31. PMID:2752667. |
these results suggest that, although csf ache activity is not a useful parameter in the diagnosis of dementia, it may be a marker indicating abnormalities of the intracerebral cholinergic system during the process of cerebral atrophy. |
1989-08-31 |
2023-08-11 |
human |
| R Elble, E Giacobini, C Higgin. Choline levels are increased in cerebrospinal fluid of Alzheimer patients. Neurobiology of aging. vol 10. issue 1. 1989-08-31. PMID:2755556. |
we measured choline (ch), acetylcholinesterase activity (ache) and total protein in the cerebrospinal fluid (csf) of 66 alzheimer patients (ages 54-89 years) and 22 age-matched controls (ages 52-80 years), looking for markers of the well-established cholinergic deficit and neuronal degeneration in alzheimer disease (ad). |
1989-08-31 |
2023-08-11 |
Not clear |
| R Elble, E Giacobini, C Higgin. Choline levels are increased in cerebrospinal fluid of Alzheimer patients. Neurobiology of aging. vol 10. issue 1. 1989-08-31. PMID:2755556. |
the reduction in csf ache is consistent with the depletion of cholinergic neurons in ad. |
1989-08-31 |
2023-08-11 |
Not clear |
| A Rami, A Rabie, J Clo. The time course of hippocampal cholinergic innervation in the developing hypothyroid rat. A combined histochemical and biochemical study of acetylcholinesterase activity. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 7. issue 3. 1989-08-30. PMID:2756848. |
development of cholinergic innervation in the hippocampal formation of normal and hypothyroid rats was studied by a combined biochemical and histochemical analysis of acetylcholinesterase (ache) activity in normal and hypothyroid rats. |
1989-08-30 |
2023-08-11 |
rat |
| H Wen. [Postnatal ontogenesis of cholinergic fibers in the rat cerebral cortex]. Journal fur Hirnforschung. vol 30. issue 3. 1989-08-11. PMID:2745964. |
using the quantitative-histochemical evaluation of the cholinergic marker enzyme acetylcholinesterase (ache) in the epithalamus (nucleus medialis habenulae) and in different cortical areas of rats during postnatal ontogenesis it is shown that (i) the cholinergic differentation in the thalamic structure seems to be already finished immediately after birth and (ii) the cholinergic synaptogenesis in the cerebral cortex does not start until birth, but takes place postnatally in phylogenetic graduated cortices in temporal echeloned steps (paleo- greater than archi- greater than neocortex). |
1989-08-11 |
2023-08-11 |
rat |
| K Suga. [The effects of ischemia and postischemic reperfusion on the brain cholinergic system of the rat]. Masui. The Japanese journal of anesthesiology. vol 38. issue 3. 1989-08-04. PMID:2739067. |
using experimental cerebral ischemia induced in rats with 4-vessel occlusion, the effects of 2-hour ischemia (ligation group) and 30-minute ischemia followed by 72-hour reperfusion (reperfusion group) on cholinergic system (chs) was investigated with acetylcholine receptor (achr), choline acetyltransferase (cat) and acetylcholine esterase (ache) as indicators of chs in seven sections of the brain. |
1989-08-04 |
2023-08-11 |
rat |
| R Martinez-Murillo, F Semenenko, A C Cuell. The origin of tyrosine hydroxylase-immunoreactive fibers in the regions of the nucleus basalis magnocellularis of the rat. Brain research. vol 451. issue 1-2. 1989-07-31. PMID:2908026. |
the simultaneous use of acetylcholinesterase (ache) histochemistry and tyrosine hydroxylase (t-oh) immunocytochemistry permitted demonstration of the existence of a dense catecholaminergic network surrounding cholinergic neurons within the nucleus basalis magnocellularis (nbm) of the rat. |
1989-07-31 |
2023-08-11 |
rat |