| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Kreissl, G Bicke. Histochemistry of acetylcholinesterase and immunocytochemistry of an acetylcholine receptor-like antigen in the brain of the honeybee. The Journal of comparative neurology. vol 286. issue 1. 1989-10-03. PMID:2768558. |
a particularly striking overlap of achr immunoreactivity and ache staining was found in the lip neuropile of the mushroom bodies, which would suggest a cholinergic input into this neuropile via fibers of the median antennoglomerular tract. |
1989-10-03 |
2023-08-11 |
bee |
| G R Babu, G R Reddy, C S Chett. Benthiocarb toxicity on rat brain AChE. Biochemistry international. vol 19. issue 1. 1989-09-29. PMID:2775302. |
benthiocarb effect on rat brain acetylcholinesterase (ache) has been studied to know the toxic effects of benthiocarb on mammalian cholinergic systems. |
1989-09-29 |
2023-08-11 |
rat |
| R W Russell, R A Booth, C A Smith, D J Jenden, M Roch, K M Rice, S D Lauret. Roles of neurotransmitter receptors in behavior: recovery of function following decreases in muscarinic receptor density induced by cholinesterase inhibition. Behavioral neuroscience. vol 103. issue 4. 1989-09-27. PMID:2765189. |
cholinergic neurotransmitter levels were elevated in rat brain by reducing its inactivating enzyme, acetylcholinesterase (ache), with an anti-ache agent. |
1989-09-27 |
2023-08-11 |
rat |
| E J Mufson, M Bothwell, L B Hersh, J H Kordowe. Nerve growth factor receptor immunoreactive profiles in the normal, aged human basal forebrain: colocalization with cholinergic neurons. The Journal of comparative neurology. vol 285. issue 2. 1989-09-15. PMID:2547849. |
virtually all (greater than 95%) ngf receptor-containing neurons colocalize with the specific cholinergic marker choline acetyltransferase (chat) or the nonspecific marker acetylcholinesterase (ache). |
1989-09-15 |
2023-08-11 |
human |
| J Yoshinaga, T Sasaki, H Ideshita, A Hikiji, T Kuwak. [Acetylcholinesterase activity in CSF in senile dementia of Alzheimer type, vascular dementia, and Parkinson's disease]. Rinsho shinkeigaku = Clinical neurology. vol 29. issue 3. 1989-08-31. PMID:2752667. |
these results suggest that, although csf ache activity is not a useful parameter in the diagnosis of dementia, it may be a marker indicating abnormalities of the intracerebral cholinergic system during the process of cerebral atrophy. |
1989-08-31 |
2023-08-11 |
human |
| R Elble, E Giacobini, C Higgin. Choline levels are increased in cerebrospinal fluid of Alzheimer patients. Neurobiology of aging. vol 10. issue 1. 1989-08-31. PMID:2755556. |
we measured choline (ch), acetylcholinesterase activity (ache) and total protein in the cerebrospinal fluid (csf) of 66 alzheimer patients (ages 54-89 years) and 22 age-matched controls (ages 52-80 years), looking for markers of the well-established cholinergic deficit and neuronal degeneration in alzheimer disease (ad). |
1989-08-31 |
2023-08-11 |
Not clear |
| R Elble, E Giacobini, C Higgin. Choline levels are increased in cerebrospinal fluid of Alzheimer patients. Neurobiology of aging. vol 10. issue 1. 1989-08-31. PMID:2755556. |
the reduction in csf ache is consistent with the depletion of cholinergic neurons in ad. |
1989-08-31 |
2023-08-11 |
Not clear |
| A Rami, A Rabie, J Clo. The time course of hippocampal cholinergic innervation in the developing hypothyroid rat. A combined histochemical and biochemical study of acetylcholinesterase activity. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 7. issue 3. 1989-08-30. PMID:2756848. |
development of cholinergic innervation in the hippocampal formation of normal and hypothyroid rats was studied by a combined biochemical and histochemical analysis of acetylcholinesterase (ache) activity in normal and hypothyroid rats. |
1989-08-30 |
2023-08-11 |
rat |
| H Wen. [Postnatal ontogenesis of cholinergic fibers in the rat cerebral cortex]. Journal fur Hirnforschung. vol 30. issue 3. 1989-08-11. PMID:2745964. |
using the quantitative-histochemical evaluation of the cholinergic marker enzyme acetylcholinesterase (ache) in the epithalamus (nucleus medialis habenulae) and in different cortical areas of rats during postnatal ontogenesis it is shown that (i) the cholinergic differentation in the thalamic structure seems to be already finished immediately after birth and (ii) the cholinergic synaptogenesis in the cerebral cortex does not start until birth, but takes place postnatally in phylogenetic graduated cortices in temporal echeloned steps (paleo- greater than archi- greater than neocortex). |
1989-08-11 |
2023-08-11 |
rat |
| K Suga. [The effects of ischemia and postischemic reperfusion on the brain cholinergic system of the rat]. Masui. The Japanese journal of anesthesiology. vol 38. issue 3. 1989-08-04. PMID:2739067. |
using experimental cerebral ischemia induced in rats with 4-vessel occlusion, the effects of 2-hour ischemia (ligation group) and 30-minute ischemia followed by 72-hour reperfusion (reperfusion group) on cholinergic system (chs) was investigated with acetylcholine receptor (achr), choline acetyltransferase (cat) and acetylcholine esterase (ache) as indicators of chs in seven sections of the brain. |
1989-08-04 |
2023-08-11 |
rat |
| R Martinez-Murillo, F Semenenko, A C Cuell. The origin of tyrosine hydroxylase-immunoreactive fibers in the regions of the nucleus basalis magnocellularis of the rat. Brain research. vol 451. issue 1-2. 1989-07-31. PMID:2908026. |
the simultaneous use of acetylcholinesterase (ache) histochemistry and tyrosine hydroxylase (t-oh) immunocytochemistry permitted demonstration of the existence of a dense catecholaminergic network surrounding cholinergic neurons within the nucleus basalis magnocellularis (nbm) of the rat. |
1989-07-31 |
2023-08-11 |
rat |
| B E Jones, H H Webste. Neurotoxic lesions of the dorsolateral pontomesencephalic tegmentum-cholinergic cell area in the cat. I. Effects upon the cholinergic innervation of the brain. Brain research. vol 451. issue 1-2. 1989-07-31. PMID:3251579. |
the effects of these lesions upon the cholinergic innervation of the brain were investigated by comparison of brains with and without lesions which were processed for acetylcholinesterase (ache) silver, copper thiocholine histochemistry and chat radio-immunohistochemistry. |
1989-07-31 |
2023-08-11 |
cat |
| B E Jones, H H Webste. Neurotoxic lesions of the dorsolateral pontomesencephalic tegmentum-cholinergic cell area in the cat. I. Effects upon the cholinergic innervation of the brain. Brain research. vol 451. issue 1-2. 1989-07-31. PMID:3251579. |
all of these nuclei receive a rich cholinergic innervation evident in both ache histochemistry and chat immunohistochemistry. |
1989-07-31 |
2023-08-11 |
cat |
| H M Sobkowicz, M R Emmerlin. Development of acetylcholinesterase-positive neuronal pathways in the cochlea of the mouse. Journal of neurocytology. vol 18. issue 2. 1989-07-17. PMID:2732759. |
development of the cholinergic enzymes, choline acetyltransferase (chat) and ache, and of the ache-positive innervation in the cochlea was studied biochemically and morphologically in the postnatal mouse up to 26 days. |
1989-07-17 |
2023-08-11 |
mouse |
| R N Dimova, K G Usunof. Cortical projection of giant neostriatal neurons in the cat. Light and electron microscopic horseradish peroxidase study. Brain research bulletin. vol 22. issue 3. 1989-06-15. PMID:2713722. |
the simultaneous demonstration of retrogradely transported hrp and acetylcholinesterase (ache) suggest that the large neurons are presumably cholinergic. |
1989-06-15 |
2023-08-11 |
cat |
| N Tønder, T Sørensen, J Zimmer, M B Jørgensen, F F Johansen, N H Dieme. Neural grafting to ischemic lesions of the adult rat hippocampus. Experimental brain research. vol 74. issue 3. 1989-06-01. PMID:2707327. |
judged by the ache staining the grafts were innervated by cholinergic host septohippocampal fibers. |
1989-06-01 |
2023-08-11 |
rat |
| D Casper, P Davie. Stimulation of choline acetyltransferase activity by retinoic acid and sodium butyrate in a cultured human neuroblastoma. Brain research. vol 478. issue 1. 1989-04-27. PMID:2924123. |
choline acetyltransferase (acetyl-coa:choline o-acetyltransferase, ec 2.3.1.6, abbreviated chat), the biosynthetic enzyme for acetylcholine and acetylcholinesterase (ec 3.1.1.7, abbreviated ache) are expressed in a human cholinergic neuroblastoma cell line, mc-ixc. |
1989-04-27 |
2023-08-11 |
human |
| E C Hirsch, A M Graybiel, L B Hersh, C Duyckaerts, Y Agi. Striosomes and extrastriosomal matrix contain different amounts of immunoreactive choline acetyltransferase in the human striatum. Neuroscience letters. vol 96. issue 2. 1989-04-24. PMID:2522606. |
the cholinergic neuropil was not uniformly distributed in the striatum, and especially in the caudate nucleus chat-poor zones corresponding to acetylcholinesterase (ache)-poor striosomes were identified. |
1989-04-24 |
2023-08-11 |
human |
| M Eriksdotter-Nilsson, S Skirboll, T Ebendal, L Hersh, J Grassi, J Massoulié, L Olso. NGF treatment promotes development of basal forebrain tissue grafts in the anterior chamber of the eye. Experimental brain research. vol 74. issue 1. 1989-04-24. PMID:2924843. |
following pretreatment with diisopropylfluorophosphate (dfp), the cholinergic neurons in the grafts were analyzed using three morphological markers: antibodies to cholineacetyltransferase (chat), antibodies to acetylcholinesterase (ache ab) and acetylcholinesterase histochemistry (ache). |
1989-04-24 |
2023-08-11 |
rat |
| S Kish, H Karlinsky, L Becker, J Gilbert, M Rebbetoy, L J Chang, L DiStefano, O Hornykiewic. Down's syndrome individuals begin life with normal levels of brain cholinergic markers. Journal of neurochemistry. vol 52. issue 4. 1989-04-21. PMID:2522539. |
we measured the activities of the cholinergic marker enzymes choline acetyltransferase (chat) and acetylcholinesterase (ache) in autopsied brains of seven infants (age range 3 months to 1 year) with down's syndrome (ds), a disorder in which virtually all individuals will develop by middle age the neuropathological changes of alzheimer's disease accompanied by a marked brain cholinergic reduction. |
1989-04-21 |
2023-08-11 |
Not clear |