| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Naumann, T Deller, R Bender, M Frotsche. 192 IgG-saporin-induced loss of cholinergic neurons in the septum abolishes cholinergic sprouting after unilateral entorhinal lesion in the rat. The European journal of neuroscience. vol 9. issue 6. 1997-09-03. PMID:9215714. |
however, a recent report has questioned this concept, suggesting that ache may not be an adequate marker to monitor cholinergic sprouting and that other, non-cholinergic axons sprouting after entorhinal cortex lesion cause the dense ache-positive band in the denervated outer molecular layer. |
1997-09-03 |
2023-08-12 |
rat |
| T Naumann, T Deller, R Bender, M Frotsche. 192 IgG-saporin-induced loss of cholinergic neurons in the septum abolishes cholinergic sprouting after unilateral entorhinal lesion in the rat. The European journal of neuroscience. vol 9. issue 6. 1997-09-03. PMID:9215714. |
in order to determine the contribution of cholinergic septohippocampal fibres to the dense ache band appearing after entorhinal cortex lesion, the neurotoxin 192 igg-saporin, known to destroy cholinergic neurons in the basal forebrain selectively, was used. |
1997-09-03 |
2023-08-12 |
rat |
| T Naumann, T Deller, R Bender, M Frotsche. 192 IgG-saporin-induced loss of cholinergic neurons in the septum abolishes cholinergic sprouting after unilateral entorhinal lesion in the rat. The European journal of neuroscience. vol 9. issue 6. 1997-09-03. PMID:9215714. |
the cholinergic sprouting response in the molecular layer, as visualized with ache histochemistry, was abolished in all animals treated with immunotoxin. |
1997-09-03 |
2023-08-12 |
rat |
| T Naumann, T Deller, R Bender, M Frotsche. 192 IgG-saporin-induced loss of cholinergic neurons in the septum abolishes cholinergic sprouting after unilateral entorhinal lesion in the rat. The European journal of neuroscience. vol 9. issue 6. 1997-09-03. PMID:9215714. |
these data indicate that the dense ache band forming after entorhinal cortex lesion represents the sprouting of cholinergic septohippocampal fibres. |
1997-09-03 |
2023-08-12 |
rat |
| B Nehru, R Du. The effect of dietary selenium on lead neurotoxicity. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 16. issue 1. 1997-09-03. PMID:9256932. |
along with these, a decrease in acetylcholine esterase (ache) and monoamine oxidase (mao) was seen, thus affecting both cholinergic and adrenergic neurotransmitters. |
1997-09-03 |
2023-08-12 |
rat |
| C Andres, R Beeri, A Friedman, E Lev-Lehman, S Henis, R Timberg, M Shani, H Sore. Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 15. 1997-08-27. PMID:9223334. |
to explore the possibility that overproduction of neuronal acetylcholinesterase (ache) confers changes in both cholinergic and morphogenic intercellular interactions, we studied developmental responses to neuronal ache overexpression in motoneurons and neuromuscular junctions of ache-transgenic mice. |
1997-08-27 |
2023-08-12 |
mouse |
| C Andres, R Beeri, A Friedman, E Lev-Lehman, S Henis, R Timberg, M Shani, H Sore. Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 15. 1997-08-27. PMID:9223334. |
these findings demonstrate embryonic feedback mechanisms to neuronal ache overexpression that are attributable to both cholinergic and cell-cell interaction pathways, suggesting that embryonic neurexin ibeta expression is concerted in vivo with ache levels and indicating that postnatal changes in neuronal ache-associated proteins may be involved in late-onset neuromotor pathologies. |
1997-08-27 |
2023-08-12 |
mouse |
| A Lucić, B Radić, M Peraica, M Mesić, I Primozic, Z Binenfel. Antidotal efficacy of quinuclidinium oximes against soman poisoning. Archives of toxicology. vol 71. issue 7. 1997-08-21. PMID:9209694. |
the results indicate that the in vivo effectiveness of quinuclidinium oximes against soman poisoning may not be related to reactivation or protection of ache but rather to some other mechanism of the cholinergic system. |
1997-08-21 |
2023-08-12 |
mouse |
| P G Layer, J Berger, N Kink. Cholinesterases precede "ON-OFF" channel dichotomy in the embryonic chick retina before onset of synaptogenesis. Cell and tissue research. vol 288. issue 3. 1997-08-15. PMID:9134854. |
both levels can be detected easily in the mature retina by choline acetyltransferase (chat) or by acetylcholinesterase (ache); however, the usefulness of these enzymes as developmental markers is restricted, since chat is detected too late, while ache labels not only cholinergic neuropil. |
1997-08-15 |
2023-08-12 |
chicken |
| T Fujii, Y Mori, T Tominaga, I Hayasaka, K Kawashim. Maintenance of constant blood acetylcholine content before and after feeding in young chimpanzees. Neuroscience letters. vol 227. issue 1. 1997-07-30. PMID:9178849. |
the results of the present study indicate that the blood ach of chimpanzees is distributed mainly in the blood cell fraction, and that the blood ach content is not regulated directly by cholinergic nerve activity or by plasma ache activity. |
1997-07-30 |
2023-08-12 |
chimpanzee |
| S Yamada, T Fujii, K Kawashim. Oral administration of KW-5092, a novel gastroprokinetic agent with acetylcholinesterase inhibitory and acetylcholine release enhancing activities, causes a dose-dependent increase in the blood acetylcholine content of beagle dogs. Neuroscience letters. vol 225. issue 1. 1997-07-24. PMID:9143009. |
oral administration of kw-5092 (10-30 mg/kg), a gastroprokinetic agent with acetylcholinesterase (ache) inhibitory and ach release enhancing activities, caused a dose-dependent increase in the ach content of both the blood and plasma, as well as several behavioral side effects due to peripheral cholinergic stimulation. |
1997-07-24 |
2023-08-12 |
Not clear |
| F Mennicken, R Quirio. Interleukin-2 increases choline acetyltransferase activity in septal-cell cultures. Synapse (New York, N.Y.). vol 26. issue 2. 1997-07-18. PMID:9131776. |
the effect of il-2 on the expression of the cholinergic phenotype was determined using choline acetyltransferase (chat) activity and acetylcholinesterase (ache) cytochemistry. |
1997-07-18 |
2023-08-12 |
Not clear |
| D Franco, A F Moorman, W H Lamer. Expression of the cholinergic signal-transduction pathway components during embryonic rat heart development. The Anatomical record. vol 248. issue 1. 1997-07-18. PMID:9143674. |
to establish whether other components of a cholinergic signal-transduction pathway are present in the embryonic heart, we localised the mrnas encoding choline acetyltransferase (chat), acetylcholinesterase (ache), and the muscarinic receptor isoforms (machrs; m1-m5). |
1997-07-18 |
2023-08-12 |
rat |
| J M Chemnitius, F Schahmirzadi, B D Gonska, H Kreuzer, R Zec. Indirect parasympathomimetic activity of the class III antiarrhythmic substance D/L-sotalol in vitro: reversible inhibition of cholinesterase isoenzymes from blood and the human central nervous system. Pharmacological research. vol 34. issue 5-6. 1997-06-16. PMID:9076843. |
non-competitive d/l-sotalol inhibition of caudate nucleus ache and the non-competitive component of erythrocyte ache inhibition cannot be overcome by increased concentrations of the cholinergic transmitter acetylcholine (ach). |
1997-06-16 |
2023-08-12 |
human |
| J R Delfs, D M Saroff, Y Nishida, J Friend, C Geul. Effects of NMDA and its antagonists on ventral horn cholinergic neurons in organotypic roller tube spinal cord cultures. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 1. 1997-06-16. PMID:9085191. |
neurotoxic effects of excitatory amino acid (eaa) receptor agonist n-methyl-d-aspartic acid (nmda) and its antagonists on ventral horn cholinergic neurons were studied in organotypic rollertube cultures of spinal cord (otc-scs) using biochemical assays of choline acetyltransferase (chat) and acetylcholinesterase (ache) activity, and ache histochemistry. |
1997-06-16 |
2023-08-12 |
Not clear |
| T G Beach, W G Honer, L H Hughe. Cholinergic fibre loss associated with diffuse plaques in the non-demented elderly: the preclinical stage of Alzheimer's disease? Acta neuropathologica. vol 93. issue 2. 1997-06-03. PMID:9039461. |
cholinergic fibre densities were estimated in sections stained using acetylcholinesterase (ache) enzyme histochemistry. |
1997-06-03 |
2023-08-12 |
Not clear |
| A E Reyes, D R Perez, A Alvarez, J Garrido, M K Gentry, B P Doctor, N C Inestros. A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme. Biochemical and biophysical research communications. vol 232. issue 3. 1997-05-19. PMID:9126330. |
a monoclonal antibody (mab) 25b1 directed against fetal bovine-serum acetylcholinesterase (fbs ache) was used to examine the ability of the cholinergic enzyme to promote the assembly of amyloid-beta peptides (a beta) into alzheimerś fibrils. |
1997-05-19 |
2023-08-12 |
Not clear |
| K Hirai, K Kato, T Nakayama, H Hayako, Y Ishihara, G Goto, M Miyamot. Neurochemical effects of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1-b enzazepin-8-yl)-1-propanone fumarate (TAK-147), a novel acetylcholinesterase inhibitor, in rats. The Journal of pharmacology and experimental therapeutics. vol 280. issue 3. 1997-04-11. PMID:9067312. |
these results suggest that tak-147 activates the central cholinergic system by specific inhibition of ache activity without affecting peripheral butyrylcholinesterase activity, and that tak-147 also moderately activates the monoaminergic systems. |
1997-04-11 |
2023-08-12 |
rat |
| C J Gordo. Thermoregulatory aspects of environmental exposure to anticholinesterase agents. Reviews on environmental health. vol 11. issue 3. 1997-03-20. PMID:9000302. |
ache inhibition elicits cholinergic stimulation in the central nervous system and in peripheral tissues and organs, which can lead to marked dysfunction of homeostatic systems, including temperature regulation. |
1997-03-20 |
2023-08-12 |
rat |
| C J Gordo. Thermoregulatory aspects of environmental exposure to anticholinesterase agents. Reviews on environmental health. vol 11. issue 3. 1997-03-20. PMID:9000302. |
thus, the antiche-induced effects on body temperature and other physiological systems cannot be explained solely by the immediate consequences of ache inhibition and stimulation of cholinergic systems. |
1997-03-20 |
2023-08-12 |
rat |