| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aleksandro S Da Silva, Silvia G Monteiro, Jamile F Gonçalves, Rosélia Spanevello, Roberta Schmatz, Camila B Oliveira, Marcio M Costa, Raqueli T França, Jeandre A S Jaques, Maria Rosa C Schetinger, Cinthia M Mazzanti, Sonia T A Lope. Trypanosoma evansi: immune response and acetylcholinesterase activity in lymphocytes from infected rats. Experimental parasitology. vol 127. issue 2. 2011-02-15. PMID:21036170. |
therefore, the infection by t. evansi influences ache activity in lymphocytes of rats indicating changes in the responses of cholinergic system in acute phase, possibly due to immune functions performed by these enzymes. |
2011-02-15 |
2023-08-12 |
rat |
| O Soukup, Z Kristofikova, J Proska, G Tobin, J Patocka, J Marek, D Jun, J Fusek, D Ripova, K Kuc. Novel acetylcholinesterase reactivator K112 and its cholinergic properties. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 64. issue 8. 2011-02-09. PMID:20634031. |
its cholinergic properties could be of importance at op poisoning and are not related to the ache reactivation that has been studied. |
2011-02-09 |
2023-08-12 |
rat |
| O Soukup, Z Kristofikova, J Proska, G Tobin, J Patocka, J Marek, D Jun, J Fusek, D Ripova, K Kuc. Novel acetylcholinesterase reactivator K112 and its cholinergic properties. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 64. issue 8. 2011-02-09. PMID:20634031. |
these cholinergic effects include a weak inhibition of ache (ic(50)=43.8 ± 4.88 μm), inhibition of binding to the porcine muscarinic m2 receptor (ic(50)=4.36 μm) and finally, the inhibition of hacu (68.4 ± 9.9%), a key regulatory step in the synthesis of ach. |
2011-02-09 |
2023-08-12 |
rat |
| Pravinkumar Bhutada, Yogita Mundhada, Kuldeep Bansod, Chetan Bhutada, Santosh Tawari, Pankaj Dixit, Dharmendra Mundhad. Ameliorative effect of quercetin on memory dysfunction in streptozotocin-induced diabetic rats. Neurobiology of learning and memory. vol 94. issue 3. 2011-01-27. PMID:20620214. |
diabetes-related cognitive dysfunction is a consequence of changes within the central nervous system that are secondary to chronic hyperglycemia, oxidative stress, and cholinergic dysfunction, and probably therefore anti-diabetics, anti-oxidants, and acetylcholine esterase (ache) inhibitors were found to have beneficial effects in animal models. |
2011-01-27 |
2023-08-12 |
rat |
| Houjuan Xing, Ying Han, Shu Li, Jintao Wang, Xu Wang, Shiwen X. Alterations in mRNA expression of acetylcholinesterase in brain and muscle of common carp exposed to atrazine and chlorpyrifos. Ecotoxicology and environmental safety. vol 73. issue 7. 2011-01-24. PMID:20696475. |
alteration in transcription of ache caused by atr, cpf, and their mixture could reveal the toxic mechanisms related to cholinergic signaling. |
2011-01-24 |
2023-08-12 |
Not clear |
| Hajer Attig, Alessandro Dagnino, Alessandro Negri, Jamel Jebali, Hamadi Boussetta, Aldo Viarengo, Francesco Dondero, Mohamed Bann. Uptake and biochemical responses of mussels Mytilus galloprovincialis exposed to sublethal nickel concentrations. Ecotoxicology and environmental safety. vol 73. issue 7. 2011-01-24. PMID:20800282. |
the cholinergic system was evaluated using the acetylcholinesterase activity (ache). |
2011-01-24 |
2023-08-12 |
Not clear |
| Mohammad A Kamal, M Reale, Abdulaziz A Al-Jafar. Multiple approaches to analyse the data for rat brain acetylcholinesterase inhibition by cyclophosphamide. Neurochemical research. vol 35. issue 10. 2011-01-18. PMID:20652634. |
acetylcholinesterase (ache) is an externally oriented membrane-bound enzyme and its main physiological role is termination of chemical transmission at cholinergic synapses and secretory organs by rapid hydrolysis of the neurotransmitter acetylcholine (ach). |
2011-01-18 |
2023-08-12 |
rat |
| Zaineb Henderson, Nazia Matto, Danielle John, Natalia N Nalivaeva, Anthony J Turne. Co-localization of PRiMA with acetylcholinesterase in cholinergic neurons of rat brain: an immunocytochemical study. Brain research. vol 1344. 2011-01-10. PMID:20471375. |
previously it has been found that principal cholinergic neurons in the brain express high concentrations of ache enzymic activity at their neuronal membranes. |
2011-01-10 |
2023-08-12 |
rat |
| Zaineb Henderson, Nazia Matto, Danielle John, Natalia N Nalivaeva, Anthony J Turne. Co-localization of PRiMA with acetylcholinesterase in cholinergic neurons of rat brain: an immunocytochemical study. Brain research. vol 1344. 2011-01-10. PMID:20471375. |
a strong association of ache with prima at the plasma membrane is therefore a feature specific to principal cholinergic neurons that innervate the central nervous system. |
2011-01-10 |
2023-08-12 |
rat |
| Rosilene R Kaizer, Jessié M Gutierres, Roberta Schmatz, Rosélia M Spanevello, Vera M Morsch, Maria R C Schetinger, João B T Roch. In vitro and in vivo interactions of aluminum on NTPDase and AChE activities in lymphocytes of rats. Cellular immunology. vol 265. issue 2. 2010-11-16. PMID:20832780. |
these results may demonstrate the ability of al to elicit the immune system, where ntpdase and ache activities can act as purinergic and cholinergic markers in lymphocytes. |
2010-11-16 |
2023-08-12 |
rat |
| Tatsuya Kikuchi, Toshimitsu Okamura, Kiyoshi Fukushi, Toshiaki Iri. Piperidine-4-methanthiol ester derivatives for a selective acetylcholinesterase assay. Biological & pharmaceutical bulletin. vol 33. issue 4. 2010-11-12. PMID:20410609. |
the activity of acetylcholinesterase (ache) is measured to obtain pathological information about the cholinergic system in various disease states and to assess the effect of ache inhibitors. |
2010-11-12 |
2023-08-12 |
human |
| Einor Ben Assayag, Shani Shenhar-Tsarfaty, Keren Ofek, Lilach Soreq, Irena Bova, Ludmila Shopin, Ronan M G Berg, Shlomo Berliner, Itzhak Shapira, Natan M Bornstein, Hermona Sore. Serum cholinesterase activities distinguish between stroke patients and controls and predict 12-month mortality. Molecular medicine (Cambridge, Mass.). vol 16. issue 7-8. 2010-11-08. PMID:20464061. |
our study sought diagnostic values of ache and cholinergic status (cs, the total capacity for acetylcholine hydrolysis) in suspected stroke patients. |
2010-11-08 |
2023-08-12 |
Not clear |
| Bombi Lee, Bong-Jun Sur, Jeong-Jun Han, Insop Shim, Song Her, Hye-Jung Lee, Dae-Hyun Hah. Krill phosphatidylserine improves learning and memory in Morris water maze in aged rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 6. 2010-11-02. PMID:20677367. |
changes in the cholinergic system were examined by measuring choline acetyltransferase (chat) and acetylcholinesterase (ache) immunoreactivity in the hippocampus. |
2010-11-02 |
2023-08-12 |
rat |
| Kazim Husain, Rais A Ansari, Leon Ferde. Pharmacological agents in the prophylaxis/treatment of organophosphorous pesticide intoxication. Indian journal of experimental biology. vol 48. issue 7. 2010-10-21. PMID:20929049. |
poisoning includes acute cholinergic crisis as a result of ache inhibition, intermediate syndrome (ims) due to neuromuscular necrosis and organophosphate-induced delayed neuropathy (opidn) due to inhibition of neuropathy target esterase (nte). |
2010-10-21 |
2023-08-12 |
human |
| Yoshihiko Ito, Taketsugu Harada, Kasumi Fushimi, Yoshiyuki Kagawa, Hidenobu Oka, Hiroshi Nakazawa, Reiko Homma, Yoshihisa Kato, Shizuo Yamad. Pharmacokinetic and pharmacodynamic analysis of acetylcholinesterase inhibition by distigmine bromide in rats. Drug metabolism and pharmacokinetics. vol 25. issue 3. 2010-10-12. PMID:20610884. |
distigmine bromide (distigmine) is associated with a serious adverse reaction, cholinergic crisis, due to a marked decrease in serum acetylcholinesterase (ache) levels. |
2010-10-12 |
2023-08-12 |
rat |
| Chunyuan Luo, Carolyn Chambers, Nagarajan Pattabiraman, Min Tong, Prasanthi Tipparaju, Ashima Saxen. Y124 at the peripheral anionic site is important for the reactivation of nerve agent-inhibited acetylcholinesterase by H oximes. Biochemical pharmacology. vol 80. issue 9. 2010-10-06. PMID:20655881. |
the toxicity of organophosphorus (op) nerve agents is manifested through irreversible inhibition of acetylcholinesterase (ache) at the cholinergic synapses, which stops nerve signal transmission, resulting in a cholinergic crisis and eventually death of the poisoned person. |
2010-10-06 |
2023-08-12 |
human |
| Chunyuan Luo, Carolyn Chambers, Nagarajan Pattabiraman, Min Tong, Prasanthi Tipparaju, Ashima Saxen. Y124 at the peripheral anionic site is important for the reactivation of nerve agent-inhibited acetylcholinesterase by H oximes. Biochemical pharmacology. vol 80. issue 9. 2010-10-06. PMID:20655881. |
oxime compounds used in nerve agent antidote regimen reactivate nerve agent-inhibited ache and halt the development of this cholinergic crisis. |
2010-10-06 |
2023-08-12 |
human |
| Ethika Tyagi, Rahul Agrawal, Chandishwar Nath, Rakesh Shukl. Effect of melatonin on neuroinflammation and acetylcholinesterase activity induced by LPS in rat brain. European journal of pharmacology. vol 640. issue 1-3. 2010-10-04. PMID:20450904. |
to study the cholinergic intervention during neuroinflammatory conditions acetylcholinesterase (ache) enzyme activity was taken as marker of cholinergic activity. |
2010-10-04 |
2023-08-12 |
rat |
| Steeve Hervé Thany, Hélène Tricoire-Leignel, Bruno Lapie. Identification of cholinergic synaptic transmission in the insect nervous system. Advances in experimental medicine and biology. vol 683. 2010-09-30. PMID:20737784. |
a major criteria initially used to localize cholinergic neuronal elements in nervous systems tissues that involve acetylcholine (ach) as neurotransmitter is mainly based on immunochemical studies using choline acetyltransferase (chat), an enzyme which catalyzes ach biosynthesis and the ach degradative enzyme named acetylcholinesterase (ache). |
2010-09-30 |
2023-08-12 |
Not clear |
| Yanzi Zhou, Shenglong Wang, Yingkai Zhan. Catalytic reaction mechanism of acetylcholinesterase determined by Born-Oppenheimer ab initio QM/MM molecular dynamics simulations. The journal of physical chemistry. B. vol 114. issue 26. 2010-09-27. PMID:20550161. |
acetylcholinesterase (ache) is a remarkably efficient serine hydrolase responsible for the termination of impulse signaling at cholinergic synapses. |
2010-09-27 |
2023-08-12 |
Not clear |