| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Giustina, P Desenzani, P Perini, E Bazzigaluppi, C Bodini, S Bossoni, C Poiesi, W B Wehrenberg, E Bos. Glutamate decarboxylase autoimmunity and growth hormone secretion in type I diabetes mellitus. Metabolism: clinical and experimental. vol 46. issue 4. 1997-05-08. PMID:9109840. |
the aim of the study was to ascertain the influence of the presence and activity of the autoimmune process involving a key enzyme (glutamic acid decarboxylase [gad]) in the synthetic pathway of a neurotransmitter regulating somatostatin secretion, ie, gamma-aminobutyric acid (gaba), on the gh response to ghrh alone or combined with an acetylcholinesterase inhibitor, pyridostigmine (pd), in patients with type i diabetes mellitus. |
1997-05-08 |
2023-08-12 |
human |
| T Cowen, C Thrasivoulou, S A Shaw, T A Abdel-Rahma. Transplanted sweat glands from mature and aged donors determine cholinergic phenotype and altered density of host sympathetic nerves. Journal of the autonomic nervous system. vol 60. issue 3. 1997-02-20. PMID:8912274. |
markers have been used which indicate changes in nerve fibre morphology (the pan-neuronal marker, pgp9.5) as well as neurotransmitter expression (acetylcholinesterase (ache), vasocative intestinal polypeptide (vip) and tyrosine hydroxylase (th). |
1997-02-20 |
2023-08-12 |
rat |
| V Tõugu, T Kesvater. Role of ionic interactions in cholinesterase catalysis. Biochimica et biophysica acta. vol 1298. issue 1. 1997-01-06. PMID:8948485. |
acetylcholinesterase (ache, ec 3.1.1.7) is an enzyme terminating the transmission of nerve impulse in synapses by rapid and selective hydrolysis of the neurotransmitter acetylcholine. |
1997-01-06 |
2023-08-12 |
Not clear |
| T Cowen, C Thrasivoulou, S A Shaw, T A Abdel-Rahma. Transplanted sweat glands from mature and aged donors determine cholinergic phenotype and altered density of host sympathetic nerves. Journal of the autonomic nervous system. vol 58. issue 3. 1996-11-12. PMID:8738308. |
markers have been used which indicate changes in nerve fibre morphology (the pan-neuronal marker, pgp9.5) as well as neurotransmitter expression (acetylcholinesterase (ache), vasocative intestinal polypeptide (vip) and tyrosine hydroxylase (th)). |
1996-11-12 |
2023-08-12 |
rat |
| L Peng, I Silman, J Sussman, M Goeldne. Biochemical evaluation of photolabile precursors of choline and of carbamylcholine for potential time-resolved crystallographic studies on cholinesterases. Biochemistry. vol 35. issue 33. 1996-09-30. PMID:8718877. |
acetylcholinesterase and butyrylcholinesterase both rapidly hydrolyze the neurotransmitter acetylcholine. |
1996-09-30 |
2023-08-12 |
Not clear |
| W Tong, E R Collantes, Y Chen, W J Wels. A comparative molecular field analysis study of N-benzylpiperidines as acetylcholinesterase inhibitors. Journal of medicinal chemistry. vol 39. issue 2. 1996-02-28. PMID:8558505. |
these compounds have been found to inhibit the metabolic breakdown of the neurotransmitter acetylcholine (ach) by the enzyme acetylcholinesterase (ache) and hence alleviate memory deficits in patients with alzheimer's disease by potentiating cholinergic transmission. |
1996-02-28 |
2023-08-12 |
human |
| D Julka, R Sandhir, K D Gil. Altered cholinergic metabolism in rat CNS following aluminum exposure: implications on learning performance. Journal of neurochemistry. vol 65. issue 5. 1995-12-04. PMID:7595502. |
al, at a dose of 10 mg/kg of body weight/day for 4 weeks, had a deleterious effect on the activities of biosynthetic (choline acetyltransferase) and hydrolytic (acetylcholinesterase) enzymes of the neurotransmitter acetylcholine. |
1995-12-04 |
2023-08-12 |
rat |
| V Coiro, R Volpi, L Capretti, R Colla, G Caffarri, P P Vescovi, P Chioder. Dopaminergic and cholinergic control of arginine-vasopressin secretion in type I diabetic men. European journal of clinical investigation. vol 25. issue 6. 1995-10-05. PMID:7656919. |
in order to verify whether similar neurotransmitter alterations also affect the regulation of posterior pituitary hormone secretion, the arginine-vasopressin (avp) responses to the dopaminergic agonist apomorphine and in a different occasion to physostigmine, an acetylcholinesterase inhibitor, were evaluated in normal (n = 10) and type i diabetics (n = 16). |
1995-10-05 |
2023-08-12 |
human |
| M F Otterson, T R Koch, Z Zhang, S C Leming, J E Moulde. Fractionated irradiation alters enteric neuroendocrine products. Digestive diseases and sciences. vol 40. issue 8. 1995-09-28. PMID:7544259. |
increased neuronal synthesis and inhibition of neurotransmitter release are potential explanations for elevated tissue concentrations of vip, substance p, and acetylcholinesterase. |
1995-09-28 |
2023-08-12 |
Not clear |
| E P Hornstein, D L Sambursky, S C Chamberlai. Histochemical localization of acetylcholinesterase in the lateral eye and brain of Limulus polyphemus: might acetylcholine be a neurotransmitter for lateral inhibition in the lateral eye? Visual neuroscience. vol 11. issue 5. 1994-12-12. PMID:7947410. |
histochemical localization of acetylcholinesterase in the lateral eye and brain of limulus polyphemus: might acetylcholine be a neurotransmitter for lateral inhibition in the lateral eye? |
1994-12-12 |
2023-08-12 |
horseshoe_crab |
| K Bulloch, T Damavandy, M Badamchia. Characterization of choline O-acetyltransferase (ChAT) in the BALB/C mouse spleen. The International journal of neuroscience. vol 76. issue 1-2. 1994-12-05. PMID:7960463. |
the synthesizing enzyme, choline-o-acetyl transferase (chat) (ec 2.3.1.6) and the degradation enzyme, acetylcholinesterase (ec 3.1.1.7) for the neurotransmitter acetylcholine, have been anatomically and biochemically characterized in the thymus of the balb/c mouse. |
1994-12-05 |
2023-08-12 |
mouse |
| P A Lapchak, D M Araujo, F Heft. Effects of chronic nerve growth factor treatment on hippocampal [3H]cytisine/nicotinic binding sites and presynaptic nicotinic receptor function following fimbrial transections. Neuroscience. vol 60. issue 2. 1994-09-23. PMID:8072684. |
thus, in studies that used partial fimbriectomies to parallel the cholinergic neurodegeneration that occurs in ad, intraventricularly administered nerve growth factor prevented the loss of choline acetyltransferase (chat) and acetylcholinesterase immunoreactivity in the septum and increased a variety of presynaptic cholinergic markers involved in the synthesis, storage and release of the neurotransmitter acetylcholine (for reviews see refs 7, 17, 19). |
1994-09-23 |
2023-08-12 |
Not clear |
| L C Anderson, J R Garret. The effects of streptozotocin-induced diabetes on norepinephrine and cholinergic enzyme activities in rat parotid and submandibular glands. Archives of oral biology. vol 39. issue 2. 1994-06-16. PMID:8185504. |
therefore, glandular levels of the adrenergic neurotransmitter, norepinephrine (ne) and two cholinergic enzymes, choline acetyltransferase (chat) and acetylcholinesterase (ache), were investigated in 6-month streptozotocin-diabetic rats. |
1994-06-16 |
2023-08-12 |
rat |
| J G Clemen. Chromodacryorrhea in rats: absence following soman poisoning. Toxicology and applied pharmacology. vol 124. issue 1. 1994-02-18. PMID:8291061. |
soman (pinacolyl methylphosphonofluoridate), a potent irreversible inhibitor of acetylcholinesterase which increases the synaptic concentration of the neurotransmitter acetylcholine, did not induce chromodacryorrhea in rats. |
1994-02-18 |
2023-08-12 |
rat |
| B L Schlaggar, J A De Carlos, D D O'Lear. Acetylcholinesterase as an early marker of the differentiation of dorsal thalamus in embryonic rats. Brain research. Developmental brain research. vol 75. issue 1. 1993-12-10. PMID:8222210. |
the enzyme acetylcholinesterase (ache) is transiently expressed in rats by neurons of the principal sensory thalamic nuclei, although these neurons do not use acetylcholine as a neurotransmitter. |
1993-12-10 |
2023-08-12 |
rat |
| J L Sussman, M Harel, I Silma. Three-dimensional structure of acetylcholinesterase and of its complexes with anticholinesterase drugs. Chemico-biological interactions. vol 87. issue 1-3. 1993-09-03. PMID:8343975. |
based on our recent x-ray crystallographic determination of the structure of acetylcholinesterase (ache) from torpedo californica, we can see for the first time, at atomic resolution, a protein binding pocket for the neurotransmitter, acetylcholine. |
1993-09-03 |
2023-08-12 |
Not clear |
| U Keseberg, W J Schmid. Tetrahydroaminoacridine attenuates dizocilpine-induced behavioural changes. Behavioural brain research. vol 53. issue 1-2. 1993-05-11. PMID:8466656. |
the acetylcholinesterase inhibitor tetrahydroaminoacridine (tha) is known to interact with neurotransmitter systems other than the cholinergic, e.g. |
1993-05-11 |
2023-08-12 |
rat |
| N Yasmeen, Nayeemunnis. Insecticide induced disruptions in functioning of developing brain of Rana cyanophlictis. Indian journal of experimental biology. vol 30. issue 8. 1993-01-14. PMID:1459649. |
remarkable inhibition of enzymes acetylcholinesterase and choline acetylase and significant accumulation of neurotransmitter acetylcholine were observed in permethrin treated animals. |
1993-01-14 |
2023-08-11 |
Not clear |
| A V Sergutin. [A cytochemical study of the effect of tuftsin on the enzyme activity in functionally different formations of the brain in rats]. Tsitologiia. vol 33. issue 12. 1992-11-18. PMID:1841460. |
no changes of activity of neurotransmitter metabolism enzymes (monoamine oxidase, acetylcholinesterase) were registered cytochemically. |
1992-11-18 |
2023-08-11 |
rat |
| M Z Wrona, R N Goyal, D J Turk, C L Blank, G Dryhurs. 5,5'-Dihydroxy-4,4'-bitryptamine: a potentially aberrant, neurotoxic metabolite of serotonin. Journal of neurochemistry. vol 59. issue 4. 1992-10-26. PMID:1357095. |
furthermore, an unidentified autoxidation product of this neurotransmitter is an inhibitor of acetylcholinesterase (ache), an enzyme compromised in the alzheimer brain. |
1992-10-26 |
2023-08-11 |
mouse |