All Relations between acetylcholinesterase and neurotransmitter

Publication Sentence Publish Date Extraction Date Species
Y Sarne, B K Schrier, H Gaine. Evidence for the local synthesis of a transmitter enzyme (glutamic acid decarboxylase) in crayfish peripheral nerve. Brain research. vol 110. issue 1. 1976-09-01. PMID:1276952. the activities of three enzymes of neurotransmitter metabolism (choline acetyl-transferase, cat; acetylcholinesterase, ache; and glutamic acid decarboxylase, gad) were studied in normal, transected, and organ cultured crayfish nerves. 1976-09-01 2023-08-11 cat
J D Minna, J Yavelow, H G Coo. Expression of phenotypes in hybrid somatic cells derived from the nervous system. Genetics. vol 79 Suppl. 1975-11-05. PMID:1150088. the ability to synthesize ach and the ability to degrade this neurotransmitter (high levels of acetylcholinesterase activity, ache) appear to segregate independently in nl hybrid progeny.--when a a variety of clonal cell lines replicating in culture are fused to cells freshly derived from the embryonic nervous system, interesting phenotypes result in the hybrid progeny. 1975-11-05 2023-08-11 mouse
J G Clement, E H Colhou. Presynaptic effect of the aziridinium ion of acetylcholine mustard (methyl-2-acetoxyethyl-2'-chloroethylamine) on the phrenic nerve--rat diaphragm preparation. Canadian journal of physiology and pharmacology. vol 53. issue 2. 1975-09-09. PMID:165868. although difficult to prove with the rat diaphragm it is possible that acetylcholinesterase of this preparation could hydrolyze acetylcholine mustard aziridinium ion at the neurotransmitter site and the resultant choline mustard aziridinium ion would interfere with the uptake of choline and eventually prevent neuromuscular transmission. 1975-09-09 2023-08-11 mouse