| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B L Schlaggar, J A De Carlos, D D O'Lear. Acetylcholinesterase as an early marker of the differentiation of dorsal thalamus in embryonic rats. Brain research. Developmental brain research. vol 75. issue 1. 1993-12-10. PMID:8222210. |
the enzyme acetylcholinesterase (ache) is transiently expressed in rats by neurons of the principal sensory thalamic nuclei, although these neurons do not use acetylcholine as a neurotransmitter. |
1993-12-10 |
2023-08-12 |
rat |
| J L Sussman, M Harel, I Silma. Three-dimensional structure of acetylcholinesterase and of its complexes with anticholinesterase drugs. Chemico-biological interactions. vol 87. issue 1-3. 1993-09-03. PMID:8343975. |
based on our recent x-ray crystallographic determination of the structure of acetylcholinesterase (ache) from torpedo californica, we can see for the first time, at atomic resolution, a protein binding pocket for the neurotransmitter, acetylcholine. |
1993-09-03 |
2023-08-12 |
Not clear |
| U Keseberg, W J Schmid. Tetrahydroaminoacridine attenuates dizocilpine-induced behavioural changes. Behavioural brain research. vol 53. issue 1-2. 1993-05-11. PMID:8466656. |
the acetylcholinesterase inhibitor tetrahydroaminoacridine (tha) is known to interact with neurotransmitter systems other than the cholinergic, e.g. |
1993-05-11 |
2023-08-12 |
rat |
| N Yasmeen, Nayeemunnis. Insecticide induced disruptions in functioning of developing brain of Rana cyanophlictis. Indian journal of experimental biology. vol 30. issue 8. 1993-01-14. PMID:1459649. |
remarkable inhibition of enzymes acetylcholinesterase and choline acetylase and significant accumulation of neurotransmitter acetylcholine were observed in permethrin treated animals. |
1993-01-14 |
2023-08-11 |
Not clear |
| A V Sergutin. [A cytochemical study of the effect of tuftsin on the enzyme activity in functionally different formations of the brain in rats]. Tsitologiia. vol 33. issue 12. 1992-11-18. PMID:1841460. |
no changes of activity of neurotransmitter metabolism enzymes (monoamine oxidase, acetylcholinesterase) were registered cytochemically. |
1992-11-18 |
2023-08-11 |
rat |
| M Z Wrona, R N Goyal, D J Turk, C L Blank, G Dryhurs. 5,5'-Dihydroxy-4,4'-bitryptamine: a potentially aberrant, neurotoxic metabolite of serotonin. Journal of neurochemistry. vol 59. issue 4. 1992-10-26. PMID:1357095. |
furthermore, an unidentified autoxidation product of this neurotransmitter is an inhibitor of acetylcholinesterase (ache), an enzyme compromised in the alzheimer brain. |
1992-10-26 |
2023-08-11 |
mouse |
| E E Tyrala, S V Mathews, G S Ra. Effect of intrauterine exposure to cocaine on acetylcholinesterase in primary cultures of fetal mouse brain cells. Neurotoxicology and teratology. vol 14. issue 4. 1992-10-15. PMID:1522827. |
the effect of in utero exposure to cocaine on the developmental pattern of acetylcholinesterase (ache), a major regulator of the central nervous system neurotransmitter acetylcholine, was studied in fetal brain cell cultures collected from mice on gestational day 15 after maternal exposure to cocaine from gestational days 6-14. |
1992-10-15 |
2023-08-11 |
mouse |
| S K Dutta, K Das, B Ghosh, C F Blackma. Dose dependence of acetylcholinesterase activity in neuroblastoma cells exposed to modulated radio-frequency electromagnetic radiation. Bioelectromagnetics. vol 13. issue 4. 1992-09-24. PMID:1510740. |
to explore the physiological importance of these findings, we have examined the impact of rfr exposure on a membrane-bound enzyme, acetylcholinesterase (ache), which is intimately involved with the acetylcholine (ach) neurotransmitter system. |
1992-09-24 |
2023-08-11 |
Not clear |
| J M de Gandarias, J Irazusta, E Echevarría, J Gil, L Casí. [Acetylcholinesterase activity during the cortical development of the cat brain]. Archivos de neurobiologia. vol 55. issue 3. 1992-09-08. PMID:1497415. |
acetylcholinesterase (ache) hydrolyses acetylcholine to choline and acetate, thereby inactivating the neurotransmitter. |
1992-09-08 |
2023-08-11 |
cat |
| H Soreq, Y Lapidot-Lifson, H Zaku. A role for cholinesterases in tumorigenesis? Cancer cells (Cold Spring Harbor, N.Y. : 1989). vol 3. issue 12. 1992-08-06. PMID:1820094. |
hydrolysis of the neurotransmitter acetylcholine by acetylcholinesterase (ache) and butyrylcholinesterase (bche) is the rate-limiting step in the termination of cholinergic signaling at neuromuscular junctions. |
1992-08-06 |
2023-08-11 |
human |
| D D Lund, G A Davey, A R Subieta, B J Pardin. Compensatory recovery of parasympathetic control of heart rate after unilateral vagotomy in rabbits. The American journal of physiology. vol 262. issue 4 Pt 2. 1992-05-21. PMID:1566894. |
vagal stimulation during acetylcholinesterase inhibition by physostigmine and direct neuroeffector stimulation by methacholine indicated that a change in metabolism of the neurotransmitter or an increased sensitivity of the tissue to acetylcholine were not responsible for augmentation of vagal responses. |
1992-05-21 |
2023-08-11 |
Not clear |
| H Hörtnagl, M L Berger, G Sperk, C Pif. Regional heterogeneity in the distribution of neurotransmitter markers in the rat hippocampus. Neuroscience. vol 45. issue 2. 1992-02-07. PMID:1684835. |
in these six hippocampal subregions the concentrations of noradrenaline, dopamine, serotonin, 3-methoxy-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid and the putative neurotransmitter amino acids glutamate, aspartate, gaba, glycine and taurine, and the levels of somatostatin and neuropeptide y and the activities of choline acetyltransferase, acetylcholinesterase and glutamate decarboxylase were measured. |
1992-02-07 |
2023-08-11 |
rat |
| N K Dash, M Azam, G Gupta, N Z Baque. Effect of hyperglycemia on acetylcholinesterase and catecholamine levels in rat brain and heart. Biochemistry international. vol 23. issue 2. 1991-08-29. PMID:1859430. |
the decreased activity of acetylcholinesterase observed in diabetes may be due to an early impaired glucose oxidation and glucose transport as a result of lack of insulin, which causes specific alterations in neurotransmitter levels, thereby effecting blood brain barrier transport, thus causing brain dysfunction. |
1991-08-29 |
2023-08-11 |
rat |
| M Mildenberger, T G Beach, E G McGeer, C M Ludgat. An animal model of prophylactic cranial irradiation: histologic effects at acute, early and delayed stages. International journal of radiation oncology, biology, physics. vol 18. issue 5. 1990-07-06. PMID:2347714. |
immunohistochemistry for neurotransmitter synthetic enzymes tyrosine hydroxylase and glutamate decarboxylase, as well as histochemistry for acetylcholinesterase, failed to uncover any changes in the irradiated animals. |
1990-07-06 |
2023-08-11 |
rat |
| R W Russell, R A Booth, C A Smith, D J Jenden, M Roch, K M Rice, S D Lauret. Roles of neurotransmitter receptors in behavior: recovery of function following decreases in muscarinic receptor density induced by cholinesterase inhibition. Behavioral neuroscience. vol 103. issue 4. 1989-09-27. PMID:2765189. |
cholinergic neurotransmitter levels were elevated in rat brain by reducing its inactivating enzyme, acetylcholinesterase (ache), with an anti-ache agent. |
1989-09-27 |
2023-08-11 |
rat |
| R J Polinsky, K V Holmes, R T Brown, V Weis. CSF acetylcholinesterase levels are reduced in multiple system atrophy with autonomic failure. Neurology. vol 39. issue 1. 1989-02-09. PMID:2909912. |
the lack of correlation between the low enzyme levels and low csf levels of monoamine metabolites in these patients indicates that the acetylcholinesterase reduction is not directly related to disruption in these neurotransmitter systems. |
1989-02-09 |
2023-08-11 |
Not clear |
| T Ostholm, P Ekström, A Bruun, T van Vee. Temporal disparity in pineal and retinal ontogeny. Brain research. vol 470. issue 1. 1988-10-11. PMID:3165685. |
the development of photoreceptors and two putative neurotransmitter systems in the pineal organ and retina was studied during embryogenesis in the three-spined stickleback gasterosteus aculeatus l. the investigation was performed by aid of immunocytochemistry using well characterized antisera to the retinal proteins alpha-transducin (td alpha) and s-antigen (sa) (photoreceptor-markers), antisera against l-glutamic acid decarboxylase (gad), gamma-aminobutyric acid (gaba), choline-o-acetyltransferase (chat) and with acetylcholinesterase (ache) histochemistry (neurotransmitter-markers). |
1988-10-11 |
2023-08-11 |
Not clear |
| P W Grabham, R J Grand, P J Byrd, P H Gallimor. Differentiation of normal and adenovirus-12 E1 transformed human embryo retinal cells. Experimental eye research. vol 47. issue 1. 1988-10-07. PMID:2842175. |
activity of the neurotransmitter enzyme acetylcholinesterase was also detected and found to increase after differentiation. |
1988-10-07 |
2023-08-11 |
mouse |
| P K Datta, A Banerjee, P S Basu, T K Datt. Acetylcholinesterase (EC 3.1.1.7), a neurotransmitter enzyme in scorpion hemolymph. Biochemical pharmacology. vol 37. issue 5. 1988-04-07. PMID:2964237. |
acetylcholinesterase (ec 3.1.1.7), a neurotransmitter enzyme in scorpion hemolymph. |
1988-04-07 |
2023-08-11 |
Not clear |
| T Wichmann, R B Illing, K Stark. Evidence for a neurotransmitter function of acetylcholine in rabbit superior colliculus. Neuroscience. vol 23. issue 3. 1988-04-05. PMID:2893996. |
acetylcholinesterase staining and studies on the uptake of [3h]choline into the subsequent efflux of tritium from collicular slices were carried out in order to provide evidence for a neurotransmitter function of acetylcholine in rabbit superior colliculus. |
1988-04-05 |
2023-08-11 |
rabbit |