| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S K Arora, G Kau. Effect of insulin induced hypoglycemia on acetylcholinesterase and Na+, K(+)-ATPase activity of rat heart, liver and kidney. Biochemistry and molecular biology international. vol 31. issue 3. 1994-04-04. PMID:8118415. |
the effect of insulin induced hypoglycemia was studied on the activities of acetylcholinesterase (ache) which hydrolizes acetylcholine (ach) and na+, k(+)-atpase, the enzymatic version of na+,k(+)-pump from rat heart, liver and kidney. |
1994-04-04 |
2023-08-12 |
rat |
| M K Gilson, T P Straatsma, J A McCammon, D R Ripoll, C H Faerman, P H Axelsen, I Silman, J L Sussma. Open "back door" in a molecular dynamics simulation of acetylcholinesterase. Science (New York, N.Y.). vol 263. issue 5151. 1994-04-04. PMID:8122110. |
the enzyme acetylcholinesterase generates a strong electrostatic field that can attract the cationic substrate acetylcholine to the active site. |
1994-04-04 |
2023-08-12 |
Not clear |
| J Eichler, A Anselment, J L Sussman, J Massoulié, I Silma. Differential effects of "peripheral" site ligands on Torpedo and chicken acetylcholinesterase. Molecular pharmacology. vol 45. issue 2. 1994-03-31. PMID:8114681. |
comparison of the effect of three 'peripheral' site ligands, propidium, d-tubocurarine, and gallamine, on acetylcholinesterase (acetylcholine hydrolase; ec 3.1.1.7) of torpedo and chicken shows that all three are substantially more effective inhibitors of the torpedo enzyme than of the chicken enzyme. |
1994-03-31 |
2023-08-12 |
chicken |
| J Eichler, A Anselment, J L Sussman, J Massoulié, I Silma. Differential effects of "peripheral" site ligands on Torpedo and chicken acetylcholinesterase. Molecular pharmacology. vol 45. issue 2. 1994-03-31. PMID:8114681. |
the concentration dependence of activity towards the natural substrate acetylcholine is almost identical for the two enzymes, whereas substrate inhibition of chicken acetylcholinesterase is somewhat weaker than that of the torpedo enzyme. |
1994-03-31 |
2023-08-12 |
chicken |
| Z Huang, R Villarta-Snow, G J Lubrano, G G Guilbaul. Development of choline and acetylcholine Pt microelectrodes. Analytical biochemistry. vol 215. issue 1. 1994-02-28. PMID:8297012. |
choline (ch) and acetylcholine (ach) microenzyme sensors were developed based on the immobilization of choline oxidase (cho) and acetylcholinesterase (ache) at the tip of a 25-micron pt wire sealed in glass. |
1994-02-28 |
2023-08-12 |
Not clear |
| J G Clemen. Chromodacryorrhea in rats: absence following soman poisoning. Toxicology and applied pharmacology. vol 124. issue 1. 1994-02-18. PMID:8291061. |
soman (pinacolyl methylphosphonofluoridate), a potent irreversible inhibitor of acetylcholinesterase which increases the synaptic concentration of the neurotransmitter acetylcholine, did not induce chromodacryorrhea in rats. |
1994-02-18 |
2023-08-12 |
rat |
| J G Clemen. Chromodacryorrhea in rats: absence following soman poisoning. Toxicology and applied pharmacology. vol 124. issue 1. 1994-02-18. PMID:8291061. |
the lack of the following, inhibition of harderian gland acetylcholinesterase and elevation of the synaptic concentration of acetylcholine, could explain the absence of chromodacryorrhea following soman poisoning. |
1994-02-18 |
2023-08-12 |
rat |
| A D Wolfe, P K Chiang, B P Doctor, N Fryar, J P Rhee, M Saee. Monoclonal antibody AE-2 modulates carbamate and organophosphate inhibition of fetal bovine serum acetylcholinesterase. Molecular pharmacology. vol 44. issue 6. 1994-01-26. PMID:8264551. |
the monoclonal antibody ae-2, raised against the human erythrocyte acetylcholinesterase (ache) dimer (acetylcholine acetylhydrolase, ec 3.1.1.7), binds to other mammalian aches, including the tetramer that occurs in fetal bovine serum (fbs). |
1994-01-26 |
2023-08-12 |
human |
| S Bursztajn, Y J Jong, S A Berma. Differential distribution of vesicular carriers during differentiation and synapse formation. Journal of cellular biochemistry. vol 53. issue 3. 1994-01-25. PMID:8263042. |
both acetylcholine receptors (achr) and acetylcholinesterase (ache) are transported via coated vesicles, some of which accumulate beneath the neuromuscular synapse where achrs cluster. |
1994-01-25 |
2023-08-12 |
mouse |
| K Tanaka, N Ogawa, M Asanuma, H Hirata, Y Kondo, N Nakayama, A Mor. Effects of the acetylcholinesterase inhibitor ENA-713 on ischemia-induced changes in acetylcholine and aromatic amine levels in the gerbil brain. Archives internationales de pharmacodynamie et de therapie. vol 323. 1993-12-30. PMID:8250645. |
effects of the acetylcholinesterase inhibitor ena-713 on ischemia-induced changes in acetylcholine and aromatic amine levels in the gerbil brain. |
1993-12-30 |
2023-08-12 |
Not clear |
| K Tanaka, N Ogawa, M Asanuma, H Hirata, Y Kondo, N Nakayama, A Mor. Effects of the acetylcholinesterase inhibitor ENA-713 on ischemia-induced changes in acetylcholine and aromatic amine levels in the gerbil brain. Archives internationales de pharmacodynamie et de therapie. vol 323. 1993-12-30. PMID:8250645. |
the effects of a new acetylcholinesterase inhibitor, ena-713, on ischemia-induced changes in acetylcholine, monoamines, and their metabolites, were studied in the gerbil. |
1993-12-30 |
2023-08-12 |
Not clear |
| S P Hardy, P M Smith, R Bayston, L Spit. Electrogenic colonic ion transport in Hirschsprung's disease: reduced secretion to the neural secretagogues acetylcholine and iloprost. Gut. vol 34. issue 10. 1993-12-23. PMID:7694888. |
the ganglionic colon proximal to the aganglionic colon also had a reduced response to acetylcholine despite a normal acetylcholinesterase staining pattern. |
1993-12-23 |
2023-08-12 |
Not clear |
| S P Hardy, P M Smith, R Bayston, L Spit. Electrogenic colonic ion transport in Hirschsprung's disease: reduced secretion to the neural secretagogues acetylcholine and iloprost. Gut. vol 34. issue 10. 1993-12-23. PMID:7694888. |
the hypertrophied acetylcholinesterase positive nerve fibres that infiltrate the aganglionic colon are likely to contribute to the reduced secretion to acetylcholine. |
1993-12-23 |
2023-08-12 |
Not clear |
| b' T D Djoki\\xc4\\x8. [The role of enkephalinase (neutral endopeptidase) in neurogenic inflammation of the respiratory tract]. Glas. Srpska akademija nauka i umetnosti. Odeljenje medicinskih nauka. issue 42. 1993-12-16. PMID:1340478.' |
we released that degradative mechanisms could play an important role in modulating tachykinin effects, just as acetylcholinesterase modulates effects of acetylcholine released from nerve terminals. |
1993-12-16 |
2023-08-11 |
Not clear |
| E Messamore, U Warpman, E Williams, E Giacobin. Muscarinic receptors mediate attenuation of extracellular acetylcholine levels in rat cerebral cortex after cholinesterase inhibition. Neuroscience letters. vol 158. issue 2. 1993-12-14. PMID:8233096. |
these observations suggest that the extracellular concentration of acetylcholine following moderate acetylcholinesterase inhibition is regulated through muscarinic receptors. |
1993-12-14 |
2023-08-12 |
rat |
| B L Schlaggar, J A De Carlos, D D O'Lear. Acetylcholinesterase as an early marker of the differentiation of dorsal thalamus in embryonic rats. Brain research. Developmental brain research. vol 75. issue 1. 1993-12-10. PMID:8222210. |
the enzyme acetylcholinesterase (ache) is transiently expressed in rats by neurons of the principal sensory thalamic nuclei, although these neurons do not use acetylcholine as a neurotransmitter. |
1993-12-10 |
2023-08-12 |
rat |
| F Amenta, F Franch, A Ricci, J A Veg. Cholinergic neurotransmission in the hippocampus of aged rats: influence of L-alpha-glycerylphosphorylcholine treatment. Annals of the New York Academy of Sciences. vol 695. 1993-12-10. PMID:8239302. |
the influence of aging and of l-alpha-glycerylphosphorylcholine (gfc) treatment on the acetylcholine synthesizing and degradating enzymes choline acetyltransferase (chat) and acetylcholinesterase (ache) and on cholinergic muscarinic m-1 and m-2 receptors were assessed in the hippocampus using immunocytochemical, histochemical and radioligand binding techniques, respectively. |
1993-12-10 |
2023-08-12 |
rat |
| P Shillito, A Vincent, J Newsom-Davi. Congenital myasthenic syndromes. Neuromuscular disorders : NMD. vol 3. issue 3. 1993-11-24. PMID:8400858. |
they include defects in acetylcholine release, absence of the endplate-specific form of acetylcholinesterase, and alterations in the number or function of postsynaptic acetylcholine receptors. |
1993-11-24 |
2023-08-12 |
Not clear |
| N Suneetha, R P Kuma. Ultrasound-induced enhancement of ACh, AChE and GABA in fetal brain tissue of mouse. Ultrasound in medicine & biology. vol 19. issue 5. 1993-09-23. PMID:8356785. |
the neurotransmitters, acetylcholine (ach) and gamma amino butyric acid (gaba), and the associated enzyme acetylcholinesterase (ache) levels, were estimated in the exposed fetal brains. |
1993-09-23 |
2023-08-12 |
mouse |
| A Maelicke, T Coban, A Schrattenholz, B Schröder, S Reinhardt-Maelicke, A Storch, J Godovac-Zimmermann, C Methfessel, E F Pereira, E X Albuquerqu. Physostigmine and neuromuscular transmission. Annals of the New York Academy of Sciences. vol 681. 1993-09-23. PMID:8395146. |
single channel studies carried out in cultured rat myoballs and cultured hippocampal neurons, and ion flux studies performed on torpedo electrocyte membrane vesicles, showed that physostigmine (phy), a well-established acetylcholinesterase inhibitor, interacts directly with nicotinic acetylcholine receptors (nachr). |
1993-09-23 |
2023-08-12 |
rat |