| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Funayama, M Shinkai, S Ebisawa, T Abe, I Takayanag. Effects of ageing on regional differences in the contractile responses to acetylcholine and neurokinin A in rabbit airway. General pharmacology. vol 25. issue 4. 1994-12-08. PMID:7958729. |
the pd2 value of acetylcholine changed with age in three different regions while that of carbamylcholine, which is resistant to acetylcholinesterase, did not. |
1994-12-08 |
2023-08-12 |
rabbit |
| R J Rodriguez, I A Dreshaj, G Kumar, M J Miller, R J Marti. Maturation of the cholinergic response of tracheal smooth muscle in the piglet. Pediatric pulmonology. vol 18. issue 1. 1994-12-08. PMID:7970904. |
therefore, we studied isometric contraction of tracheal smooth muscle (tsm) to evaluate the effects of maturation on 1) the response of tsm to the muscarinic agonist acetylcholine (ach); and 2) the regulatory activity of acetylcholinesterase (ache) during the early postnatal period in the piglet. |
1994-12-08 |
2023-08-12 |
Not clear |
| P E Lloyd, P J Churc. Cholinergic neuromuscular synapses in Aplysia have low endogenous acetylcholinesterase activity and a high-affinity uptake system for acetylcholine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 11 Pt 1. 1994-12-06. PMID:7965073. |
cholinergic neuromuscular synapses in aplysia have low endogenous acetylcholinesterase activity and a high-affinity uptake system for acetylcholine. |
1994-12-06 |
2023-08-12 |
aplysia |
| K Bulloch, T Damavandy, M Badamchia. Characterization of choline O-acetyltransferase (ChAT) in the BALB/C mouse spleen. The International journal of neuroscience. vol 76. issue 1-2. 1994-12-05. PMID:7960463. |
the synthesizing enzyme, choline-o-acetyl transferase (chat) (ec 2.3.1.6) and the degradation enzyme, acetylcholinesterase (ec 3.1.1.7) for the neurotransmitter acetylcholine, have been anatomically and biochemically characterized in the thymus of the balb/c mouse. |
1994-12-05 |
2023-08-12 |
mouse |
| Z Luo, M E Fuentes, P Taylo. Regulation of acetylcholinesterase mRNA stability by calcium during differentiation from myoblasts to myotubes. The Journal of biological chemistry. vol 269. issue 44. 1994-11-29. PMID:7961631. |
the expression of acetylcholinesterase (ache), nicotinic acetylcholine receptors (nachr), and their corresponding mrnas increases dramatically during the conversion of myoblasts to myotubes in c2-c12 cells. |
1994-11-29 |
2023-08-12 |
Not clear |
| F Amenta, E Bronzetti, M Mancini, J A Vega, D Zacche. Choline acetyltransferase and acetylcholinesterase in the hippocampus of aged rats: sensitivity to choline alphoscerate treatment. Mechanisms of ageing and development. vol 74. issue 1-2. 1994-11-10. PMID:7934207. |
the influence of aging on the acetylcholine synthesising and the degrading enzymes choline acetyltransferase (chat) and acetylcholinesterase (ache) was studied in the hippocampus of male wstar rats at 2 months (young), 12 months (adult) and 27 months (old) of age using biochemical, immunocytochemical and histochemical techniques. |
1994-11-10 |
2023-08-12 |
rat |
| C S Venugopalan, E P Holmes, H H Jarboe, K M Kleino. Non-adrenergic non-cholinergic (NANC) excitatory response of the channel catfish intestine. Journal of autonomic pharmacology. vol 14. issue 3. 1994-11-02. PMID:7929475. |
the contractile cholinergic responses of the tissues to carbachol and acetylcholine (ach) were blocked by atropine on an equimolar concentration, whereas, these responses were enhanced in the presence of neostigmine, and acetylcholinesterase inhibitor. |
1994-11-02 |
2023-08-12 |
Not clear |
| G Blanchet, P Carpentier, G Lallement, H Sentenac-Roumano. [Prevention and treatment of status epilepticus induced by soman]. Annales pharmaceutiques francaises. vol 52. issue 1. 1994-10-13. PMID:8085742. |
it is generally accepted that inhibition of acetylcholinesterase results in an accumulation of acetylcholine (ach) which may be responsible for the acute toxic effects of nerve agents. |
1994-10-13 |
2023-08-12 |
rat |
| P A Lapchak, D M Araujo, F Heft. Effects of chronic nerve growth factor treatment on hippocampal [3H]cytisine/nicotinic binding sites and presynaptic nicotinic receptor function following fimbrial transections. Neuroscience. vol 60. issue 2. 1994-09-23. PMID:8072684. |
thus, in studies that used partial fimbriectomies to parallel the cholinergic neurodegeneration that occurs in ad, intraventricularly administered nerve growth factor prevented the loss of choline acetyltransferase (chat) and acetylcholinesterase immunoreactivity in the septum and increased a variety of presynaptic cholinergic markers involved in the synthesis, storage and release of the neurotransmitter acetylcholine (for reviews see refs 7, 17, 19). |
1994-09-23 |
2023-08-12 |
Not clear |
| F A Abdulla, M R Calaminici, V V Raevsky, J D Sinden, J A Gray, J D Stephenso. An iontophoretic study of the effects of alpha-amino-hydroxy-5-methyl-4-isoxazole propionic acid lesions of the nucleus basalis magnocellularis on cholinergic and GABAergic influences on frontal cortex neurones of rats. Experimental brain research. vol 98. issue 3. 1994-09-15. PMID:7914493. |
the similarity of these effects to those of acetylcholine in lesioned animals suggests that the increased sensitivity to acetylcholine in the latter was due to loss of acetylcholinesterase, enabling diffusion of acetylcholine to more distant neurones. |
1994-09-15 |
2023-08-12 |
rat |
| F A Abdulla, M R Calaminici, V V Raevsky, J D Sinden, J A Gray, J D Stephenso. An iontophoretic study of the effects of alpha-amino-hydroxy-5-methyl-4-isoxazole propionic acid lesions of the nucleus basalis magnocellularis on cholinergic and GABAergic influences on frontal cortex neurones of rats. Experimental brain research. vol 98. issue 3. 1994-09-15. PMID:7914493. |
however, acetylcholinesterase does not hydrolyse carbachol and therefore it is necessary to postulate a different post-synaptic mechanism to explain the lesion-induced increases in the sensitivities of individual neurones to carbachol and to acetylcholine; interpretation of experimental findings should take these two mechanisms into account. |
1994-09-15 |
2023-08-12 |
rat |
| Y Nakai, T Okasora, E Okamot. [Studies on cholinergic nerve function of the aganglionic colon in murin model]. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi. vol 30. issue 2. 1994-09-14. PMID:8054708. |
in the aganglionic colon, no contractions were evoked by acetylcholinesterase blocking agents, indicating that there is no spontaneous release of acetylcholine. |
1994-09-14 |
2023-08-12 |
mouse |
| S Harada, I Hori, H Yamamoto, R Hoson. Mutations in the unc-41 gene cause elevation of acetylcholine levels. Journal of neurochemistry. vol 63. issue 2. 1994-08-12. PMID:8035172. |
eight recessive alleles (cn252, e268, e399, e650, e1175, e1199, e1294, and e870) lead to phenotypes including uncoordinated locomotion, slow growth, a small mature body, and resistance to the acetylcholinesterase inhibitors as well as the elevation of acetylcholine content. |
1994-08-12 |
2023-08-12 |
caenorhabditis_elegans |
| F R Sidel. Clinical effects of organophosphorus cholinesterase inhibitors. Journal of applied toxicology : JAT. vol 14. issue 2. 1994-08-05. PMID:8027505. |
nerve agents, highly toxic organophosphorus cholinesterase inhibitors, inhibit acetylcholinesterase and cause an accumulation of acetylcholine. |
1994-08-05 |
2023-08-12 |
Not clear |
| D Prieto, U Simonsen, J Martín, M Hernández, L Rivera, L Lema, P García, A García-Sacristá. Histochemical and functional evidence for a cholinergic innervation of the equine ureter. Journal of the autonomic nervous system. vol 47. issue 3. 1994-07-25. PMID:7912246. |
the distribution of acetylcholinesterase (ache)-positive nerve fibers and cells, as well as the effects of acetylcholine (ach) on ureteral smooth muscle and small resistance arteries were investigated in the equine ureter by means of histochemical, classic organ baths and myograph techniques. |
1994-07-25 |
2023-08-12 |
Not clear |
| G Kaur, S K Aror. Acetylcholinesterase and Na+,K(+)-ATPase activities in different regions of rat brain during insulin-induced hypoglycemia. Molecular and chemical neuropathology. vol 21. issue 1. 1994-06-10. PMID:8179774. |
the activities of acetylcholinesterase (acetylcholine acetylhydrolase, ec 3.1.1.7), responsible for hydrolysis of acetylcholine and na+,k(+)-atpase (mg(2+)-dependent atp phosphohydrolase, ec 3.6.1.3), which plays a crucial role in neurotransmission, were determined in four brain regions after 1, 2, and 3 h of insulin administration. |
1994-06-10 |
2023-08-12 |
rat |
| R F Villa, R Arnaboldi, B Ghigini, A Gorin. Parkinson-like disease by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) toxicity in Macaca fascicularis: synaptosomal metabolism and action of dihydroergocriptine. Neurochemical research. vol 19. issue 3. 1994-06-06. PMID:8177363. |
the enzymes were chosen according to their regulatory role and as markers of the following metabolic pathways: (a) glycolysis ((hexokinase, phosphofructokinase, lactate dehydrogenase), (b) krebs' (tca) cycle (citrate synthase, malate dehydrogenase), (c) amino acid, glutamate metabolism (glutamate dehydrogenase, glutamate-pyruvate- and glutamate-oxaloacetate-transaminases), (d) acetylcholine catabolism (acetylcholinesterase) and (e) atpases, i.e. |
1994-06-06 |
2023-08-12 |
monkey |
| b' I V Kubasov, I I Krivo\\xc4\\xa. [The effect of acetylcholine on neuromuscular transmission in the fatigued rat diaphragm with blocked acetylcholinesterase]. Fiziologicheskii zhurnal imeni I.M. Sechenova. vol 79. issue 10. 1994-05-27. PMID:8167666.' |
[the effect of acetylcholine on neuromuscular transmission in the fatigued rat diaphragm with blocked acetylcholinesterase]. |
1994-05-27 |
2023-08-12 |
rat |
| A M Tata, M Plateroti, M Cibati, S Biagioni, G Augusti-Tocc. Cholinergic markers are expressed in developing and mature neurons of chick dorsal root ganglia. Journal of neuroscience research. vol 37. issue 2. 1994-05-11. PMID:8151732. |
the presence of acetylcholinesterase has been reported in chick dorsal root ganglia at early developmental stages although acetylcholine is not known to play a role in these ganglia. |
1994-05-11 |
2023-08-12 |
chicken |
| B K Taylor, D Holloway, M P Print. A unique central cholinergic deficit in the spontaneously hypertensive rat: physostigmine reveals a bradycardia associated with sensory stimulation. The Journal of pharmacology and experimental therapeutics. vol 268. issue 3. 1994-04-25. PMID:8138921. |
furthermore, enhancement of brain acetylcholine with acetylcholinesterase inhibition (physostigmine, 50 micrograms/kg i.c.v.) |
1994-04-25 |
2023-08-12 |
rat |