| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E E Tyrala, S V Mathews, G S Ra. Effect of intrauterine exposure to cocaine on acetylcholinesterase in primary cultures of fetal mouse brain cells. Neurotoxicology and teratology. vol 14. issue 4. 1992-10-15. PMID:1522827. |
the effect of in utero exposure to cocaine on the developmental pattern of acetylcholinesterase (ache), a major regulator of the central nervous system neurotransmitter acetylcholine, was studied in fetal brain cell cultures collected from mice on gestational day 15 after maternal exposure to cocaine from gestational days 6-14. |
1992-10-15 |
2023-08-11 |
mouse |
| S K Dutta, K Das, B Ghosh, C F Blackma. Dose dependence of acetylcholinesterase activity in neuroblastoma cells exposed to modulated radio-frequency electromagnetic radiation. Bioelectromagnetics. vol 13. issue 4. 1992-09-24. PMID:1510740. |
to explore the physiological importance of these findings, we have examined the impact of rfr exposure on a membrane-bound enzyme, acetylcholinesterase (ache), which is intimately involved with the acetylcholine (ach) neurotransmitter system. |
1992-09-24 |
2023-08-11 |
Not clear |
| G Ehrlich, E Viegas-Pequignot, D Ginzberg, L Sindel, H Soreq, H Zaku. Mapping the human acetylcholinesterase gene to chromosome 7q22 by fluorescent in situ hybridization coupled with selective PCR amplification from a somatic hybrid cell panel and chromosome-sorted DNA libraries. Genomics. vol 13. issue 4. 1992-09-22. PMID:1380483. |
to establish the chromosomal location of the human ache gene encoding the acetylcholine hydrolyzing enzyme acetylcholinesterase (ache, acetylcholine acetylhydrolase, e.c. |
1992-09-22 |
2023-08-11 |
human |
| R W Mitchell, T M Murphy, A R Lef. Physiological mechanisms mediating enhanced force generation during development and immune sensitization. Canadian journal of physiology and pharmacology. vol 70. issue 4. 1992-09-17. PMID:1498727. |
we examined the development of acetylcholinesterase (achase) activity and tracheal smooth muscle (tsm) contraction elicited by acetylcholine (ach) in a swine model of maturation and a dog model of allergic bronchospasm. |
1992-09-17 |
2023-08-11 |
dog |
| G M Shutske, J D Tomer, K J Kapples, N J Hrib, J G Jurcak, G M Bores, F P Huger, W Petko, C P Smit. Aminopyridine carbamic acid esters: synthesis and potential as acetylcholinesterase inhibitors and acetylcholine releasers. Journal of pharmaceutical sciences. vol 81. issue 4. 1992-09-17. PMID:1501077. |
aminopyridine carbamic acid esters: synthesis and potential as acetylcholinesterase inhibitors and acetylcholine releasers. |
1992-09-17 |
2023-08-11 |
rat |
| G M Shutske, J D Tomer, K J Kapples, N J Hrib, J G Jurcak, G M Bores, F P Huger, W Petko, C P Smit. Aminopyridine carbamic acid esters: synthesis and potential as acetylcholinesterase inhibitors and acetylcholine releasers. Journal of pharmaceutical sciences. vol 81. issue 4. 1992-09-17. PMID:1501077. |
4-amino-3-pyridyl carbamates (2a-c) were synthesized as potential acetylcholinesterase inhibitors and acetylcholine releasers on the basis of the reported activity of the analogous n-(4-amino-3-pyridyl)-n',n'-dimethylurea (1). |
1992-09-17 |
2023-08-11 |
rat |
| L C Streichert, P B Sargen. The role of acetylcholinesterase in denervation supersensitivity in the frog cardiac ganglion. The Journal of physiology. vol 445. 1992-09-17. PMID:1501134. |
acetylcholine and carbachol bind to the same acetylcholine receptors, but, unlike acetylcholine, carbachol is resistant to hydrolysis by acetylcholinesterase. |
1992-09-17 |
2023-08-11 |
Not clear |
| L C Streichert, P B Sargen. The role of acetylcholinesterase in denervation supersensitivity in the frog cardiac ganglion. The Journal of physiology. vol 445. 1992-09-17. PMID:1501134. |
the acetylcholine sensitivity of normal cardiac ganglion cells was increased by inhibiting extracellular acetylcholinesterase with echothiophate. |
1992-09-17 |
2023-08-11 |
Not clear |
| L C Streichert, P B Sargen. The role of acetylcholinesterase in denervation supersensitivity in the frog cardiac ganglion. The Journal of physiology. vol 445. 1992-09-17. PMID:1501134. |
following the inhibition of extracellular acetylcholinesterase with echothiophate, sensitivity to acetylcholine was similar in normal and in denervated ganglion cells. |
1992-09-17 |
2023-08-11 |
Not clear |
| L C Streichert, P B Sargen. The role of acetylcholinesterase in denervation supersensitivity in the frog cardiac ganglion. The Journal of physiology. vol 445. 1992-09-17. PMID:1501134. |
the increased sensitivity to acetylcholine of cardiac ganglion cells following denervation is caused by a reduction in the hydrolysis of the transmitter by acetylcholinesterase rather than by changes in the number and/or properties of acetylcholine receptors. |
1992-09-17 |
2023-08-11 |
Not clear |
| J S Fedan, D G Fraze. Influence of epithelium on the reactivity of guinea pig isolated, perfused trachea to bronchoactive drugs. The Journal of pharmacology and experimental therapeutics. vol 262. issue 2. 1992-09-11. PMID:1501119. |
physostigmine (10(-7) m) increased the el and il potency of acetylcholine to that of carbachol (+/- epithelium), and elevated the il acetylcholine maximum response (+ epithelium); the relative role of epithelial acetylcholinesterase could not be defined. |
1992-09-11 |
2023-08-11 |
Not clear |
| J M de Gandarias, J Irazusta, E Echevarría, J Gil, L Casí. [Acetylcholinesterase activity during the cortical development of the cat brain]. Archivos de neurobiologia. vol 55. issue 3. 1992-09-08. PMID:1497415. |
acetylcholinesterase (ache) hydrolyses acetylcholine to choline and acetate, thereby inactivating the neurotransmitter. |
1992-09-08 |
2023-08-11 |
cat |
| P H Frémont, F Crossin, D Renaud, J Fontaine-Péru. In vitro regulation of the innervation pattern of quail muscle fibers by quail and mouse neurons. Differentiation; research in biological diversity. vol 49. issue 1. 1992-08-10. PMID:1624060. |
these fibres were innervated by neurons from either quail or mouse embryo spinal cord and their innervation pattern was examined by the visualization of acetylcholine receptors (ach-r) and of acetylcholinesterase (ach-e) activity at the neuromuscular contacts. |
1992-08-10 |
2023-08-11 |
mouse |
| H Soreq, Y Lapidot-Lifson, H Zaku. A role for cholinesterases in tumorigenesis? Cancer cells (Cold Spring Harbor, N.Y. : 1989). vol 3. issue 12. 1992-08-06. PMID:1820094. |
hydrolysis of the neurotransmitter acetylcholine by acetylcholinesterase (ache) and butyrylcholinesterase (bche) is the rate-limiting step in the termination of cholinergic signaling at neuromuscular junctions. |
1992-08-06 |
2023-08-11 |
human |
| G Sorrentino, I N Singh, A Hubsch, J N Kanfer, S Mykita, R Massarell. Muscarinic binding sites in a catecholaminergic human neuroblastoma cell line. Neurochemical research. vol 17. issue 3. 1992-08-05. PMID:1320213. |
acetylcholine (100 microm) plus eserine (50 microm) and bw284c55 (1 microm), an acetylcholinesterase inhibitor, reduced the binding of qnb by approximately 25%. |
1992-08-05 |
2023-08-11 |
human |
| P Ghosh, S Bhattachary. In vivo and in vitro acetylcholinesterase inhibition by metacid-50 and carbaryl in Channa punctatus under natural field condition. Biomedical and environmental sciences : BES. vol 5. issue 1. 1992-06-23. PMID:1586462. |
these insecticides effected significant inhibition of brain acetylcholinesterase (ache) activity accompanied by a concurrent increase in acetylcholine (ach). |
1992-06-23 |
2023-08-11 |
Not clear |
| D M Maxwell, R H Thomsen, S I Baski. Species differences in the negative inotropic effect of acetylcholine and soman in rat, guinea pig, and rabbit hearts. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 100. issue 3. 1992-06-18. PMID:1687557. |
there was no correlation between the species differences in the negative inotropic effect of acetylcholine in atria and the density or affinity of acetylcholinesterase or muscarinic receptors. |
1992-06-18 |
2023-08-11 |
rat |
| D M Maxwell, R H Thomsen, S I Baski. Species differences in the negative inotropic effect of acetylcholine and soman in rat, guinea pig, and rabbit hearts. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 100. issue 3. 1992-06-18. PMID:1687557. |
inhibition of atrial acetylcholinesterase with soman reduced the ec50 of acetylcholine three-fold in all species, but did not change the maximal inotropic effect of acetylcholine. |
1992-06-18 |
2023-08-11 |
rat |
| R N Khazipov, R A Giniatulli. [Effect of magnesium ions on the functional state of postsynaptic membrane by modulation of the level of non-quantal secretion of the mediator]. Neirofiziologiia = Neurophysiology. vol 24. issue 1. 1992-06-16. PMID:1584312. |
the role of non-quantal secretion (ns) of acetylcholine (ach) in shortening of miniature end-plate currents (mepc) after initial prolongation of mepc due to acetylcholinesterase (ache) inhibition was studied in the mouse diaphragm muscle under the voltage clamp conditions. |
1992-06-16 |
2023-08-11 |
mouse |
| H Zakut, Y Lapidot-Lifson, R Beeri, A Ballin, H Sore. In vivo gene amplification in non-cancerous cells: cholinesterase genes and oncogenes amplify in thrombocytopenia associated with lupus erythematosus. Mutation research. vol 276. issue 3. 1992-06-09. PMID:1374519. |
the ache and bche genes, encoding the acetylcholine hydrolysing enzymes acetylcholinesterase (ache) and butyrylcholinesterase (bche), co-amplify with several oncogenes in leukemic patients with platelet deficiency (thrombocytopenia). |
1992-06-09 |
2023-08-11 |
Not clear |