| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vincenzo Rispoli, Domenicantonio Rotiroti, Vincenzo Carelli, Felice Liberatore, Luigi Scipione, Rosario Marra, Silvano Tortorella, Barbara Di Rienz. Electroencephalographic effects induced by choline pivaloyl esters in scopolamine-treated or nucleus basalis magnocellularis lesioned rats. Pharmacology, biochemistry, and behavior. vol 78. issue 4. 2005-03-04. PMID:15301920. |
the results of the present work allow us to put forward the hypothesis that the eeg effects observed are most likely mediated through the stimulation of the cholinergic neurotransmission ensuing from enhanced cerebral levels of acetylcholine (ach) consequent upon acetylcholinesterase (ache) inhibition by choline pivaloyl esters. |
2005-03-04 |
2023-08-12 |
rat |
| C Angelini, B Baccetti, P Piomboni, S Trombino, M G Aluigi, S Stringara, L Gallus, C Falug. Acetylcholine synthesis and possible functions during sea urchin development. European journal of histochemistry : EJH. vol 48. issue 3. 2005-03-02. PMID:15590413. |
acetylcholinesterase (ache, the lytic enzyme of acetylcholine) was also found in ovarian eggs, with a similar distribution; however, it disappeared after fertilisation. |
2005-03-02 |
2023-08-12 |
Not clear |
| Hervé Allain, Danièle Bentué-Ferrer, Lucette Lacomble. [Biology of motivation]. Psychologie & neuropsychiatrie du vieillissement. vol 2. issue 3. 2005-03-01. PMID:15689330. |
acetylcholine and dopamine, at the present time, are considered as the main neurotransmitters involved in such anatomical circuits explaining that pharmacology focuses its interest on acetylcholinesterase inhibitors and dopamine agonists. |
2005-03-01 |
2023-08-12 |
Not clear |
| Filomena A Carvalho, Rui Mesquita, João Martins-Silva, Carlota Saldanh. Acetylcholine and choline effects on erythrocyte nitrite and nitrate levels. Journal of applied toxicology : JAT. vol 24. issue 6. 2005-02-15. PMID:15551380. |
acetylcholine receptors and acetylcholinesterase are present in erythrocyte membranes. |
2005-02-15 |
2023-08-12 |
human |
| Filomena A Carvalho, Rui Mesquita, João Martins-Silva, Carlota Saldanh. Acetylcholine and choline effects on erythrocyte nitrite and nitrate levels. Journal of applied toxicology : JAT. vol 24. issue 6. 2005-02-15. PMID:15551380. |
we tested the acetylcholine and choline effects on nitric oxide metabolites (nox), namely nitrites and nitrates, and observed if they are dependent on interactions with muscarinic receptors and acetylcholinesterase. |
2005-02-15 |
2023-08-12 |
human |
| Filomena A Carvalho, Rui Mesquita, João Martins-Silva, Carlota Saldanh. Acetylcholine and choline effects on erythrocyte nitrite and nitrate levels. Journal of applied toxicology : JAT. vol 24. issue 6. 2005-02-15. PMID:15551380. |
these results demonstrated that acetylcholine and choline modulate nitric oxide metabolites on erythrocytes and this effect is mediated by interactions with erythrocyte membrane muscarinic receptors and membrane enzyme acetylcholinesterase. |
2005-02-15 |
2023-08-12 |
human |
| Martine Simard, Robert van Reeku. The acetylcholinesterase inhibitors for treatment of cognitive and behavioral symptoms in dementia with Lewy bodies. The Journal of neuropsychiatry and clinical neurosciences. vol 16. issue 4. 2005-01-26. PMID:15616167. |
changes in the acetylcholine system have been reported in brains of patients with dlb, which provides a rationale for trials of acetylcholinesterase inhibitors in dlb. |
2005-01-26 |
2023-08-12 |
Not clear |
| Peter J Houghton, Joseph M Agbedahunsi, Aderonke Adegbulugb. Choline esterase inhibitory properties of alkaloids from two Nigerian Crinum species. Phytochemistry. vol 65. issue 21. 2005-01-14. PMID:15501257. |
alkaloidal extracts of bulbs from each species showed inhibition of acetylcholinesterase, an activity exploited therapeutically to raise the depressed levels of acetylcholine in the brain associated with alzheimer's disease. |
2005-01-14 |
2023-08-12 |
Not clear |
| Samuel P Fletcher, Brian C Geyer, Amy Smith, Tama Evron, Lokesh Joshi, Hermona Soreq, Tsafrir S Mo. Tissue distribution of cholinesterases and anticholinesterases in native and transgenic tomato plants. Plant molecular biology. vol 55. issue 1. 2005-01-13. PMID:15604663. |
acetylcholinesterase, a major component of the central and peripheral nervous systems, is ubiquitous among multicellular animals, where its main function is to terminate synaptic transmission by hydrolyzing the neurotransmitter, acetylcholine. |
2005-01-13 |
2023-08-12 |
human |
| Tsuneyoshi Ota, Hitoshi Shinotoh, Kiyoshi Fukushi, Shin-ichiro Nagatsuka, Hiroki Namba, Masaomi Iyo, Akiyo Aotsuka, Noriko Tanaka, Koichi Sato, Tetsuya Shiraishi, Shuji Tanada, Heii Arai, Toshiaki Iri. A simple method for the detection of abnormal brain regions in Alzheimer's disease patients using [11C]MP4A: comparison with [123I]IMP SPECT. Annals of nuclear medicine. vol 18. issue 3. 2004-12-21. PMID:15233279. |
we have developed a radiolabeled lipophilic acetylcholine analogue, n-[11c]methylpiperidin-4-yl acetate ([11c]mp4a) to measure brain acetylcholinesterase (ache) activity by positron emission tomography (pet) in vivo. |
2004-12-21 |
2023-08-12 |
Not clear |
| Mark J Millan, Alain Gobert, Sylvain Roux, Roger Porsolt, Alfredo Meneses, Mirjana Carli, Benjamin Di Cara, Robert Jaffard, Jean-Michel Rivet, Pierre Lestage, Elisabeth Mocaer, Jean-Louis Peglion, Anne Dekeyn. The serotonin1A receptor partial agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] enhances cholinergic transmission and cognitive function in rodents: a combined neurochemical and behavioral analysis. The Journal of pharmacology and experimental therapeutics. vol 311. issue 1. 2004-12-15. PMID:15146031. |
in the absence of acetylcholinesterase inhibitors, s15535 dose-dependently (0.04-5.0 mg/kg s.c.) elevated dialysis levels of acetylcholine in the frontal cortex and dorsal hippocampus of freely moving rats. |
2004-12-15 |
2023-08-12 |
mouse |
| Marjorie Pick, Cesar Flores-Flores, Dan Grisaru, Susana Shochat, Varda Deutsch, Hermona Sore. Blood-cell-specific acetylcholinesterase splice variations under changing stimuli. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 22. issue 7. 2004-12-15. PMID:15465282. |
peripheral stimuli-induced modulations in acetylcholine regulation may hence reflect blood cell lineage-dependent acetylcholinesterase splice variations. |
2004-12-15 |
2023-08-12 |
Not clear |
| S Sen, A Gülce, H Gülc. Polyvinylferrocenium modified Pt electrode for the design of amperometric choline and acetylcholine enzyme electrodes. Biosensors & bioelectronics. vol 19. issue 10. 2004-11-26. PMID:15046758. |
choline and acetylcholine enzyme electrodes were developed by co-immobilizing choline oxidase and acetylcholinesterase in polyvinylferrocenium perchlorate matrix coated on a pt electrode surface. |
2004-11-26 |
2023-08-12 |
Not clear |
| Laura E Paraoanu, Paul G Laye. Mouse acetylcholinesterase interacts in yeast with the extracellular matrix component laminin-1beta. FEBS letters. vol 576. issue 1-2. 2004-11-19. PMID:15474030. |
acetylcholinesterase (ache) is likely to have roles other than the hydrolysis of acetylcholine, e.g., related to developmental processes like neurite outgrowth, differentiation and adhesion. |
2004-11-19 |
2023-08-12 |
mouse |
| Hiroshi Nagabukuro, Satoshi Okanishi, Shigemitsu Imai, Yuji Ishichi, Yuji Ishihara, Takayuki Do. Effects of TAK-802, a novel acetylcholinesterase inhibitor, on distension-induced rhythmic bladder contractions in rats and guinea pigs. European journal of pharmacology. vol 485. issue 1-3. 2004-10-05. PMID:14757154. |
these results suggest that tak-802 and other acetylcholinesterase inhibitors can effectively increase reflex bladder contractions by increasing the efficacy of acetylcholine released by nerve impulses. |
2004-10-05 |
2023-08-12 |
rat |
| Simona Capsoni, Sabina Giannotta, Marco Stebel, Addys Ancheta Garcia, Roberta De Rosa, Gino Villetti, Bruno Pietro Imbimbo, Claudio Pietra, Antonino Cattane. Ganstigmine and donepezil improve neurodegeneration in AD11 antinerve growth factor transgenic mice. American journal of Alzheimer's disease and other dementias. vol 19. issue 3. 2004-10-05. PMID:15214201. |
ganstigmine (chf2819) is an acetylcholinesterase inhibitor that increases acetylcholine in rat hippocampus and ameliorates scopolamine-induced amnesia. |
2004-10-05 |
2023-08-12 |
mouse |
| Jiri Bajgar, Lucie Sevelová, Gabriela Krejcová, Josef Fusek, Josef Vachek, Jiri Kassa, Josef Herink, Leo P A de Jong, Hendrik P Benscho. Biochemical and behavioral effects of soman vapors in low concentrations. Inhalation toxicology. vol 16. issue 8. 2004-09-28. PMID:15204741. |
soman acts by inhibiting acetylcholinesterase (ache) both peripherally and centrally, with a subsequent accumulation of neuromediator acetylcholine and other metabolic changes. |
2004-09-28 |
2023-08-12 |
Not clear |
| Bing Ma, Philip S Sherman, James E Moskwa, Robert A Koeppe, Michael R Kilbour. Sensitivity of [11C]N-methylpyrrolidinyl benzilate ([11C]NMPYB) to endogenous acetylcholine: PET imaging vs tissue sampling methods. Nuclear medicine and biology. vol 31. issue 4. 2004-09-16. PMID:15093808. |
administration of phenserine, an acetylcholinesterase inhibitor, raises endogenous brain acetylcholine levels and has been previously shown to reduce in vivo binding of the muscarinic cholinergic receptor antagonist [(11)c]n-methylpyrrolidinyl benzilate ([(11)c]nmpyb) in the awake rat brain. |
2004-09-16 |
2023-08-12 |
human |
| Yan Qi Liang, Xi Can Tan. Comparative effects of huperzine A, donepezil and rivastigmine on cortical acetylcholine level and acetylcholinesterase activity in rats. Neuroscience letters. vol 361. issue 1-3. 2004-08-30. PMID:15135892. |
comparative effects of huperzine a, donepezil and rivastigmine on cortical acetylcholine level and acetylcholinesterase activity in rats. |
2004-08-30 |
2023-08-12 |
rat |
| Yan Qi Liang, Xi Can Tan. Comparative effects of huperzine A, donepezil and rivastigmine on cortical acetylcholine level and acetylcholinesterase activity in rats. Neuroscience letters. vol 361. issue 1-3. 2004-08-30. PMID:15135892. |
the cholinesterase inhibitors huperzine a, donepezil and rivastigmine were compared for their effects on extracellular acetylcholine concentration and acetylcholinesterase activity in the rat cortex. |
2004-08-30 |
2023-08-12 |
rat |