| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Muslum Gok, Cigdem Cicek, Ebru Bodu. Butyrylcholinesterase in lipid metabolism: A new outlook. Journal of neurochemistry. 2023-05-02. PMID:37129444. |
cholinesterase enzymes acetylcholinesterase (ache) and butyrylcholinesterase (bche) are traditionally associated with the termination of acetylcholine mediated neural signaling. |
2023-05-02 |
2023-08-14 |
Not clear |
| Sanghyeon Kim, Keon Mook Seong, Si Hyeock Le. Acetylcholine titre regulation by non-neuronal acetylcholinesterase 1 and its putative roles in honey bee physiology. Insect molecular biology. 2023-05-02. PMID:37130064. |
acetylcholine titre regulation by non-neuronal acetylcholinesterase 1 and its putative roles in honey bee physiology. |
2023-05-02 |
2023-08-14 |
bee |
| Yuting Xue, Haotian Zhong, Bin Liu, Shuo Qin, Zhengbo Chen, Kai Li, Lirong Zheng, Xia Zu. Colorimetric identification of multiple terpenoids based on bimetallic FeCu/NPCs nanozymes. Analytical biochemistry. 2023-04-27. PMID:37105389. |
terpenoids act as inhibitors of acetylcholinesterase (ache) and reduce the hydrolysis of acetylcholine (atch), providing insight into establishing a simple and distinct assay for terpenoids. |
2023-04-27 |
2023-08-14 |
Not clear |
| Patricia G Izquierdo, Claude L Charvet, Cedric Neveu, A Christopher Green, John E H Tattersall, Lindy Holden-Dye, Vincent O'Conno. Modelling organophosphate intoxication in C. elegans highlights nicotinic acetylcholine receptor determinants that mitigate poisoning. PloS one. vol 18. issue 4. 2023-04-21. PMID:37083685. |
organophosphate intoxication via acetylcholinesterase inhibition executes neurotoxicity via hyper stimulation of acetylcholine receptors. |
2023-04-21 |
2023-08-14 |
caenorhabditis_elegans |
| Hongxin Zhang, Xuegang Li, Xue Zhou, Pengqi Gong, Yong Zha. U-fiber-based biosensor for temperature-compensated acetylcholine-specific measurement. Optics letters. vol 48. issue 8. 2023-04-14. PMID:37058661. |
label-free detection of acetylcholine (ach) was achieved by immobilizing acetylcholinesterase (ache) on optical fibers. |
2023-04-14 |
2023-08-14 |
Not clear |
| Giuliano Pasquale Ramador. Organophosphorus Poisoning: Acute Respiratory Distress Syndrome (ARDS) and Cardiac Failure as Cause of Death in Hospitalized Patients. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047631. |
as the excess of acetylcholine at the neuronal level can persist for weeks until enough newly, locally synthesized acetylcholinesterase becomes available (the value of oximes in reducing this time is still under debate), after atropine administration, intravenous albumin and fluid infusion should be the first therapeutic interventions to reestablish normal blood volume and normal tissue oxygenation, avoiding death by cardiac arrest. |
2023-04-13 |
2023-08-14 |
Not clear |
| Vahulabaranan Rajagopalan, Swethaa Venkataraman, Devi Sri Rajendran, Vaidyanathan Vinoth Kumar, Vaithyanathan Vasanth Kumar, Gayathri Rangasam. Acetylcholinesterase biosensors for electrochemical detection of neurotoxic pesticides and acetylcholine neurotransmitter: A literature review. Environmental research. 2023-03-22. PMID:36948285. |
acetylcholinesterase biosensors for electrochemical detection of neurotoxic pesticides and acetylcholine neurotransmitter: a literature review. |
2023-03-22 |
2023-08-14 |
human |
| Vahulabaranan Rajagopalan, Swethaa Venkataraman, Devi Sri Rajendran, Vaidyanathan Vinoth Kumar, Vaithyanathan Vasanth Kumar, Gayathri Rangasam. Acetylcholinesterase biosensors for electrochemical detection of neurotoxic pesticides and acetylcholine neurotransmitter: A literature review. Environmental research. 2023-03-22. PMID:36948285. |
over the past few decades, acetylcholinesterase (ache) biosensors have emerged as a sensitive and reliable tool for the electrochemical detection of neurotoxic pesticides and acetylcholine. |
2023-03-22 |
2023-08-14 |
human |
| b' Rudolf Vrabec, Gerald Blunden, Lucie Cahl\\xc3\\xadkov\\xc3\\xa. Natural Alkaloids as Multi-Target Compounds towards Factors Implicated in Alzheimer\'s Disease. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36901826.' |
the current treatment, based on the cholinergic hypothesis, is only symptomatic and mainly involves the restoration of acetylcholine (ach) levels through the inhibition of acetylcholinesterase (ache). |
2023-03-11 |
2023-08-14 |
Not clear |
| Abdussamat Güze. Relationship Between Phenolic Content Determined by LC-MS/MS and Antioxidant Capacity and Enzyme Inhibition of Cyclotrichium Niveum L. Chemistry & biodiversity. 2023-03-09. PMID:36891984. |
the phytochemical composition of the plant, inhibition of acetylcholinesterase (ache) (which hydrolyzes the neurotransmitter acetylcholine), inhibition of paraoxonase for antiatherosclerotic activity (hpon 1) (which detoxifies organophosphates), and antioxidant capacity of this plant. |
2023-03-09 |
2023-08-14 |
Not clear |
| Sanjay Yadav, Punita Aggarwal, Faiz Khan, Gopal Khodve, Dibyasundar Padhy, Poonam Yadav, Sugato Banerje. β-sitosterol protects against Aluminium chloride-mediated neurotoxicity. Current Alzheimer research. 2023-03-09. PMID:36892031. |
the corticohippocampal region of the brain was isolated for acetylcholinesterase (ache), acetylcholine (ach), and gsh estimation. |
2023-03-09 |
2023-08-14 |
mouse |
| Long Sun, Xian Li, Chenjing Ma, Zhao He, Xin Zhang, Chengye Wang, Min Zhao, Jin Gan, Ying Fen. Improving Effect of the Policosanol from Foods (Basel, Switzerland). vol 11. issue 14. 2023-03-08. PMID:35885338. |
after mwm testing, the levels of acetylcholine (ach), acetylcholinesterase (ache), superoxide dismutase (sod), malondialdehyde (mda), and glutathione (gsh) that were present in brain tissue were determined using assay kits. |
2023-03-08 |
2023-08-16 |
mouse |
| Marlene Valentino, Anna Imbriano, Angelo Tricase, Flavio Della Pelle, Dario Compagnone, Eleonora Macchia, Luisa Torsi, Paolo Bollella, Nicoletta Ditarant. Electropolymerized molecularly imprinted polypyrrole film for dimethoate sensing: investigation on template removal after the imprinting process. Analytical methods : advancing methods and applications. 2023-03-02. PMID:36861684. |
dmt is an inhibitor of acetylcholinesterase (ache), which can lead to the accumulation of acetylcholine and result in symptoms related to the autonomous and central nervous systems. |
2023-03-02 |
2023-08-14 |
Not clear |
| Aleksandar R Zivkovic, Georgina M Paul, Stefan Hofer, Karsten Schmidt, Thorsten Brenner, Markus A Weigand, Sebastian O Decke. Increased Enzymatic Activity of Acetylcholinesterase Indicates the Severity of the Sterile Inflammation and Predicts Patient Outcome following Traumatic Injury. Biomolecules. vol 13. issue 2. 2023-02-25. PMID:36830636. |
acetylcholinesterase (ache), an enzyme responsible for the hydrolysis of acetylcholine, plays an essential role in controlling cholinergic activity. |
2023-02-25 |
2023-08-14 |
Not clear |
| Aravinda Babu, Mathew John, M J Liji, E Maria, S J Bhaskar, B K Binukmar, Ayyiliath M Sajith, Eeda Koti Reddy, K V Dileep, K Suni. Sub-pocket-focused designing of tacrine derivatives as potential acetylcholinesterase inhibitors. Computers in biology and medicine. vol 155. 2023-02-25. PMID:36841058. |
human acetylcholinesterase (hache) has a potential role in the management of acetylcholine, one of the neurotransmitters that modulate the overall activity of cholinergic system, ache inhibitors have a greater impact in the therapeutics. |
2023-02-25 |
2023-08-14 |
human |
| Christina Rabeler, TaiXi Gong, Danielle Ireland, Olivier Cochet-Escartin, Eva-Maria S Collin. Acetylcholinesterase Activity Staining in Freshwater Planarians. Current protocols. vol 3. issue 2. 2023-02-17. PMID:36799654. |
the serine hydrolase acetylcholinesterase (ache) is an important neuronal enzyme which catalyzes the hydrolysis of the neurotransmitter acetylcholine and other choline esters. |
2023-02-17 |
2023-08-14 |
Not clear |
| Stergiani-Chrysovalanti Peitzika, Eleni Pontik. A Review on Recent Approaches on Molecular Docking Studies of Novel Compounds Targeting Acetylcholinesterase in Alzheimer Disease. Molecules (Basel, Switzerland). vol 28. issue 3. 2023-02-11. PMID:36770750. |
low levels of acetylcholine and abnormal levels of beta-amyloid, t protein aggregation, inflammation, and oxidative stress, have been associated with ad, and therefore, research has been oriented towards the cholinergic system and primarily on acetylcholinesterase (ache) inhibitors. |
2023-02-11 |
2023-08-14 |
Not clear |
| Melvin Selim Atay, Suat Sari, Ebru Bodu. Molecular and Computational Analysis Identify Statins as Selective Inhibitors of Human Butyrylcholinesterase. The protein journal. 2023-01-17. PMID:36648628. |
cholinesterase enzyme family consists of acetylcholinesterase (ache, 3.1.1.7), the major enzyme responsible for hydrolysis of acetylcholine at cholinergic synapses, and butyrylcholinesterase (bche, 3.1.1.8) a detoxification enzyme of plasma. |
2023-01-17 |
2023-08-14 |
human |
| Sarah C Tryon, Iris M Sakamoto, Kris F Kaigler, Gabriella Gee, Jarrett Turner, Katherine Bartley, Jim R Fadel, Marlene A Wilso. ChAT::Cre transgenic rats show sex-dependent altered fear behaviors, ultrasonic vocalizations and cholinergic marker expression. Genes, brain, and behavior. 2023-01-13. PMID:36636833. |
corroborating previous studies, chat::cre+ transgenic rats overexpressed vesicular acetylcholine transporter immunolabeling in basal forebrain, striatum, basolateral amygdala, and hippocampus, but had similar levels of acetylcholinesterase and numbers of chat+ neurons as cre- rats. |
2023-01-13 |
2023-08-14 |
rat |
| Yichou Cao, Yunyi Zhang, Zehan Jia, Huining Jia, Yuanchen Sun, Hongxia Yuan, Yongle Bian, BingJie Xu, Jing Fu, Fenju Qi. Theaflavin-3,3'-digallate ameliorates learning and memory impairments in mice with premature brain aging induced by D-galactose. Physiology & behavior. 2023-01-13. PMID:36638877. |
model mice exhibited poor learning and memory in the novel object recognition and y-maze tests, reduced brain/body mass ratio, increased brain glutamate concentration and acetylcholinesterase activity, decreased brain acetylcholine concentration, and lower choline acetyltransferase, glutaminase, and glutamine synthetase activities. |
2023-01-13 |
2023-08-14 |
mouse |