| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thi Thu Ha Nguyen, Antoine Pariente, Jean-Louis Montastruc, Maryse Lapeyre-Mestre, Vanessa Rousseau, Olivier Rascol, Bernard Bégaud, François Montastru. An original pharmacoepidemiological-pharmacodynamic method: application to antipsychotic-induced movement disorders. British journal of clinical pharmacology. vol 83. issue 3. 2018-01-05. PMID:27687785. |
the aim of the present study was to combine pharmacovigilance and pharmacodynamic data to investigate the association between dopamine d2, serotonin 5ht2a, and muscarinic m1 receptor occupancy and the risks of antipsychotic drug (ap)-induced movement disorders. |
2018-01-05 |
2023-08-13 |
Not clear |
| Tatsuya Ishii, Yasuyuki Kimura, Masanori Ichise, Keisuke Takahata, Soichiro Kitamura, Sho Moriguchi, Manabu Kubota, Ming-Rong Zhang, Makiko Yamada, Makoto Higuchi, Yoshiro Okubo, Tetsuya Suhar. Anatomical relationships between serotonin 5-HT2A and dopamine D2 receptors in living human brain. PloS one. vol 12. issue 12. 2018-01-04. PMID:29220382. |
anatomical relationships between serotonin 5-ht2a and dopamine d2 receptors in living human brain. |
2018-01-04 |
2023-08-13 |
human |
| R Forcén, E Latorre, J Pardo, A I Alcalde, M D Murillo, L Gras. Toll-like receptors 2 and 4 exert opposite effects on the contractile response induced by serotonin in mouse colon: role of serotonin receptors. Experimental physiology. vol 101. issue 8. 2018-01-01. PMID:27282784. |
alterations in 5-ht2a and 5-ht2c receptors explain the increase of the response to serotonin in tlr2(-/-) mice. |
2018-01-01 |
2023-08-13 |
mouse |
| Ayaka Hori, Takashi Nishida, Shogo Takashiba, Satoshi Kubota, Masaharu Takigaw. Regulatory mechanism of CCN2 production by serotonin (5-HT) via 5-HT2A and 5-HT2B receptors in chondrocytes. PloS one. vol 12. issue 11. 2017-12-26. PMID:29145495. |
regulatory mechanism of ccn2 production by serotonin (5-ht) via 5-ht2a and 5-ht2b receptors in chondrocytes. |
2017-12-26 |
2023-08-13 |
human |
| Marc Fakhour. Revisiting the Serotonin Hypothesis: Implications for Major Depressive Disorders. Molecular neurobiology. vol 53. issue 5. 2017-12-22. PMID:25823514. |
the overarching goal of this review is to present recent findings from studies examining the serotonergic pathway in mdd, with a focus on sert and the serotonin 1a (5-ht1a), serotonin 1b (5-ht1b), and serotonin 2a (5-ht2a) receptors. |
2017-12-22 |
2023-08-13 |
mouse |
| Dhwanil A Dalwadi, Seongcheol Kim, Shahnawaz M Amdani, Zhenglan Chen, Ren-Qi Huang, John A Schet. Molecular mechanisms of serotonergic action of the HIV-1 antiretroviral efavirenz. Pharmacological research. vol 110. 2017-12-21. PMID:27157251. |
prolonged exposure to efavirenz reduces 5-ht2a receptor density and responsiveness to 5-ht. |
2017-12-21 |
2023-08-13 |
Not clear |
| Chris M Panzini, Daniel G Ehlinger, Adele M Alchahin, Yueping Guo, Kathryn G Common. 16p11.2 deletion syndrome mice perseverate with active coping response to acute stress - rescue by blocking 5-HT2A receptors. Journal of neurochemistry. vol 143. issue 6. 2017-12-20. PMID:28948999. |
taken together, these observations indicate notable changes in endogenous serotonin signaling in 16p11.2 deletion mice and support the therapeutic utility of 5-ht2a receptor antagonists. |
2017-12-20 |
2023-08-13 |
mouse |
| Chuan-Chia Chang, Wen-Hui Fang, Hsin-An Chang, Tieh-Ching Chang, Jia-Fwa Shyu, San-Yuan Huan. Serotonin 2A receptor (5-HT2A) gene promoter variant interacts with chronic perceived stress to modulate resting parasympathetic activity in humans. Psychoneuroendocrinology. vol 76. 2017-12-12. PMID:27912162. |
serotonin 2a receptor (5-ht2a) gene promoter variant interacts with chronic perceived stress to modulate resting parasympathetic activity in humans. |
2017-12-12 |
2023-08-13 |
human |
| Chuan-Chia Chang, Wen-Hui Fang, Hsin-An Chang, Tieh-Ching Chang, Jia-Fwa Shyu, San-Yuan Huan. Serotonin 2A receptor (5-HT2A) gene promoter variant interacts with chronic perceived stress to modulate resting parasympathetic activity in humans. Psychoneuroendocrinology. vol 76. 2017-12-12. PMID:27912162. |
chronic stress elevates the expression of serotonin 2a receptors (5-ht2a), while activation of 5-ht2a leads to inhibition of parasympathetic synaptic transmission. |
2017-12-12 |
2023-08-13 |
human |
| Robert T Franke, Emilia Tarland, Heidrun Fink, Heinz H Pertz, Jan Brosd. 2-Bromoterguride-a potential atypical antipsychotic drug without metabolic effects in rats. Psychopharmacology. vol 233. issue 15-16. 2017-12-11. PMID:27317020. |
recently, we showed that 2-bromoterguride acted as a dopamine d2 receptor partial agonist, a serotonin 5-ht2a and α2c-adrenergic receptor antagonist, and exhibited antidopaminergic efficacy in amphetamine-induced locomotion (ail) in rats without inducing catalepsy. |
2017-12-11 |
2023-08-13 |
rat |
| Yurie Hoashi, Satoshi Okamoto, Yuka Abe, Takashi Matsumoto, Junichi Tanaka, Yuya Yoshida, Kent Imaizumi, Kenji Mishima, Wado Akamatsu, Hideyuki Okano, Kazuyoshi Bab. Generation of neural cells using iPSCs from sleep bruxism patients with 5-HT2A polymorphism. Journal of prosthodontic research. vol 61. issue 3. 2017-11-28. PMID:27916472. |
our previous study identified a genomic association of the serotonin 2a receptor (5-ht2a) single nucleotide polymorphism (snp), rs6313 c>t, with sb, where the c allele carrier is associated with a 4.25-fold increased risk of sb. |
2017-11-28 |
2023-08-13 |
Not clear |
| Filip Tylš, Tomáš Páleníček, Lukáš Kadeřábek, Michaela Lipski, Anna Kubešová, Jiří Horáče. Sex differences and serotonergic mechanisms in the behavioural effects of psilocin. Behavioural pharmacology. vol 27. issue 4. 2017-11-20. PMID:26461483. |
the contribution of serotonin receptors in the behavioural action was tested in male rats with selective serotonin receptor antagonists: 5-ht1a receptor antagonist (way100635 1 mg/kg), 5-ht2a receptor antagonist (mdl100907 0.5 mg/kg), 5-ht2b receptor antagonist (sb215505 1 mg/kg) and 5-ht2c receptor antagonist (sb242084 1 mg/kg). |
2017-11-20 |
2023-08-13 |
rat |
| Matthew L Bank. Effects of 7-day repeated treatment with the 5-HT2A inverse agonist/antagonist pimavanserin on methamphetamine vs. food choice in male rhesus monkeys. Drug and alcohol dependence. vol 165. 2017-10-03. PMID:27242287. |
emerging data suggest that serotonin (5-ht)2a receptors modulate mesolimbic dopamine function, such that 5-ht2a antagonists blunt the abuse-related neurochemical effects of monoamine transporter substrates, such as amphetamine or methamphetamine. |
2017-10-03 |
2023-08-13 |
monkey |
| C William Heise, Hannah Malashock, Daniel E Brook. A review of vilazodone exposures with focus on serotonin syndrome effects. Clinical toxicology (Philadelphia, Pa.). vol 55. issue 9. 2017-09-11. PMID:28594246. |
serotonin syndrome is believed to be due to excessive stimulation of 5-ht2a and 5-ht1a receptors, resulting in the clinical triad of altered mentation, autonomic instability and neuromuscular abnormalities. |
2017-09-11 |
2023-08-13 |
Not clear |
| Youngjae Ryu, Toru Ogata, Motoshi Nagao, Taku Kitamura, Kazuhito Morioka, Yoshinori Ichihara, Toru Doi, Yasuhiro Sawada, Masami Akai, Ryohei Nishimura, Naoki Fujit. The swimming test is effective for evaluating spasticity after contusive spinal cord injury. PloS one. vol 12. issue 2. 2017-08-28. PMID:28182676. |
subsequently, we recorded the hoffman reflex (h-reflex) and examined the immunoreactivity of serotonin (5-ht) and its receptor (5-ht2a) in the spinal tissues of the sci rats. |
2017-08-28 |
2023-08-13 |
rat |
| Mustafa Küçükköse, Bürge Kabukçu Başa. [Acute Dystonia due to Aripiprazole Use in Two Children with Autism Spectrum Disorder in the First Five Years of Life]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 28. issue 1. 2017-08-28. PMID:28291301. |
aripiprazole is a partial agonist for the dopamine d2, serotonin 5-ht1a receptors, and an antagonist for 5ht2a receptors. |
2017-08-28 |
2023-08-13 |
Not clear |
| Feipu Yang, Xiangrui Jiang, Jianfeng Li, Yu Wang, Yongjian Liu, Minghao Bi, Chunhui Wu, Qingjie Zhao, Weiming Chen, Jingjing Yin, Jian Zhang, Yuanchao Xie, Tianwen Hu, Mingshuo Xu, Shuang Guo, Zhen Wang, Yang He, Jingshan She. Synthesis, structure-activity relationships, and biological evaluation of a series of benzamides as potential multireceptor antipsychotics. Bioorganic & medicinal chemistry letters. vol 26. issue 13. 2017-07-18. PMID:27173799. |
in the present study, a series of benzamides, endowed with potent dopamine d2, serotonin 5-ht1a and 5-ht2a receptors properties, was synthesized and evaluated as potential antipsychotics. |
2017-07-18 |
2023-08-13 |
Not clear |
| Karolina Noworyta-Sokołowska, Katarzyna Kamińska, Grzegorz Kreiner, Zofia Rogóż, Krystyna Gołembiowsk. Neurotoxic Effects of 5-MeO-DIPT: A Psychoactive Tryptamine Derivative in Rats. Neurotoxicity research. vol 30. issue 4. 2017-07-18. PMID:27461536. |
in vitro data have shown that 5-meo-dipt acts as a potent serotonin transporter (sert) inhibitor and displays high affinity at serotonin 5-ht1a, 5-ht2a, and 5-ht2c receptors. |
2017-07-18 |
2023-08-13 |
rat |
| Bing Li, Xiumei Luo, Tao Li, Changyue Zheng, Shunmei Ji, Yuanyuan Ma, Shuangshuang Zhang, Xiaodong Zho. Effects of Constant Flickering Light on Refractive Status, 5-HT and 5-HT2A Receptor in Guinea Pigs. PloS one. vol 11. issue 12. 2017-06-29. PMID:27959948. |
effects of constant flickering light on refractive status, 5-ht and 5-ht2a receptor in guinea pigs. |
2017-06-29 |
2023-08-13 |
Not clear |
| Bing Li, Xiumei Luo, Tao Li, Changyue Zheng, Shunmei Ji, Yuanyuan Ma, Shuangshuang Zhang, Xiaodong Zho. Effects of Constant Flickering Light on Refractive Status, 5-HT and 5-HT2A Receptor in Guinea Pigs. PloS one. vol 11. issue 12. 2017-06-29. PMID:27959948. |
to investigate the effects of constant flickering light on refractive development, the role of serotonin (i.e.5-hydroxytryptamine, 5-ht)and 5-ht2a receptor in myopia induced by flickering light in guinea pigs. |
2017-06-29 |
2023-08-13 |
Not clear |