| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Zaccon. Histochemical studies of epithelial mucosubstances, respiratory and pentose shunt enzymes in the skin epidermis of the air-breathing fish Mastacembelus erythrotaenia (Mastacembelidae, Pisces). Gegenbaurs morphologisches Jahrbuch. vol 128. issue 6. 1983-04-15. PMID:6219037. |
the sacciform cells produce a tryptophan rich protein and serotonin, the latter presumably acting in the control of mucus release since the n-acetylneuraminic acid is known to be an integral part of the serotonin receptor (gottschalk 1972). |
1983-04-15 |
2023-08-12 |
Not clear |
| J S Stollak, R F Furchgot. Use of selective antagonists for determining the types of receptors mediating the actions of 5-hydroxytryptamine and tryptamine in the isolated rabbit aorta. The Journal of pharmacology and experimental therapeutics. vol 224. issue 1. 1983-02-14. PMID:6129317. |
it is concluded that in this preparation trp directly activates both alpha adrenergic and 5-ht receptors and the 5-ht response is mediated by the 5-ht receptor with no involvement of alpha receptors. |
1983-02-14 |
2023-08-12 |
rabbit |
| R J Hernánde. A serotonin agonist-antagonist reversible effect on Na+-K+-ATPase activity in the developing rat brain. Developmental neuroscience. vol 5. issue 4. 1983-01-19. PMID:6291893. |
also in a state of 5-ht receptor hypersensitivity (rats treated early with 5,6-dihydroxytryptamine), the response of na+-k+-atpase to the 5-ht agonist was higher than without neurotoxic lesion of 5-ht paths. |
1983-01-19 |
2023-08-12 |
rat |
| C Ennis, B Co. The effect of tryptamine on serotonin release from hypothalamic slices is mediated by a cholinergic interneurone. Psychopharmacology. vol 78. issue 1. 1983-01-19. PMID:6815702. |
this effect of tryptamine was blocked by a series of serotonin antagonists with a relative order of potency which suggested that tryptamine was acting on a post-junctional serotonin receptor. |
1983-01-19 |
2023-08-12 |
rat |
| C A Marsden, G W Bennett, J Irons, R F Gilbert, P C Emso. Localization and release of 5-hydroxytryptamine thyrotrophin releasing hormone and substance P in rat ventral spinal cord. Comparative biochemistry and physiology. C: Comparative pharmacology. vol 72. issue 2. 1983-01-07. PMID:6183051. |
the effect of p-chloroamphetamine on trh release was not dependent on either the presence of 5-ht or 5-ht receptor activity. |
1983-01-07 |
2023-08-12 |
rat |
| I Lucki, A Fraze. Prevention of the serotonin syndrome in rats by repeated administration of monoamine oxidase inhibitors but not tricyclic antidepressants. Psychopharmacology. vol 77. issue 3. 1982-12-03. PMID:6812141. |
the serotonin syndrome was produced by the direct-acting serotonin receptor agonists 5-methoxy-n,n-dimethyltryptamine (5-medmt) or d-lysergic acid diethylamide (lsd). |
1982-12-03 |
2023-08-12 |
rat |
| S R Carr, J R Fozar. Inhibition of 5-hydroxytryptamine-evoked autonomic transmitter release by apomorphine. European journal of pharmacology. vol 81. issue 3. 1982-12-02. PMID:6126375. |
modification of 5-ht receptor function is the most likely explanation for the action of apomorphine with the differential effect on 5-ht in the heart and ileum reflecting differences in the receptors and/or post receptorial events at the two sites. |
1982-12-02 |
2023-08-12 |
rabbit |
| B Cox, C Enni. Characterization of 5-hydroxytryptaminergic autoreceptors in the rat hypothalamus. The Journal of pharmacy and pharmacology. vol 34. issue 7. 1982-12-02. PMID:6126540. |
thus we have characterized the 5-ht autoreceptor in the rat hypothalamus using a classical pharmacological approach and found that it has more in common with the autoreceptor which we have previously identified in the raphe nuclei of the rat than it has with the 5-ht receptor located on dopamine neuroterminals in the striatum. |
1982-12-02 |
2023-08-12 |
rat |
| A Biegon, T C Rainbow, B S McEwe. Quantitative autoradiography of serotonin receptors in the rat brain. Brain research. vol 242. issue 2. 1982-12-02. PMID:7116135. |
serotonin receptor distribution is found to correlate with 5-ht levels, corticosteroid and estrogen receptors in some but not all brain regions. |
1982-12-02 |
2023-08-12 |
rat |
| R F Walke. Melatonin:serotonin interaction during termination of the LH surge in rats. Progress in clinical and biological research. vol 92. 1982-10-21. PMID:7202213. |
since the effect was blocked by pretreatment with quipazine, a serotonin receptor agonist, melatonin may help terminate the lh surge by blocking serotonin neurotransmission. |
1982-10-21 |
2023-08-12 |
rat |
| R F Walke. Melatonin:serotonin interaction during termination of the LH surge in rats. Progress in clinical and biological research. vol 92. 1982-10-21. PMID:7202213. |
furthermore, the effects of melatonin and methiothepin, a serotonin receptor antagonist, on hypothalamic serotonin metabolism were comparable, and opposite from quipazine. |
1982-10-21 |
2023-08-12 |
rat |
| C Fornal, M Radulovack. Methysergide blocks the sleep suppressant action of quipazine in rats. Psychopharmacology. vol 76. issue 3. 1982-09-24. PMID:6808546. |
the aim of the present study was to examine the effect of methysergide, a 5-hydroxytryptamine (5-ht) receptor antagonist, on the sleep suppression produced by the 5-ht receptor agonist, quipazine. |
1982-09-24 |
2023-08-12 |
rat |
| J A Russell, M L Gilberstadt, M S Rohrbac. Constrictor effect of cotton bract extract on isolated canine airways. The American review of respiratory disease. vol 125. issue 6. 1982-08-07. PMID:7091879. |
we conclude that cotton bracts contain a potent 5-ht receptor agonist that appears to be distinct from 5-ht. |
1982-08-07 |
2023-08-12 |
Not clear |
| R J Barrett, M A Blackshear, E Sanders-Bus. Discriminative stimulus properties of L-5-hydroxytryptophan: behavioral evidence for multiple serotonin receptors. Psychopharmacology. vol 76. issue 1. 1982-07-19. PMID:6805004. |
further evidence for the involvement of 5-ht receptor stimulation in mediating the discrimination was that pretreatment with fluoxetine, a highly specific 5-ht uptake inhibitor, markedly potentiated the cue. |
1982-07-19 |
2023-08-12 |
rat |
| E Chung Hwang, M H Van Woer. p,p'-DDT-induced alterations in brain serotonin metabolism. Neurotoxicology. vol 2. issue 4. 1982-07-08. PMID:6176920. |
p,p'-ddt had no effect on the transport of 5-hydroxyindoleacetic acid out of the central nervous system, serotonin uptake and release from nerve terminals, or serotonin receptor binding in the brain. |
1982-07-08 |
2023-08-12 |
rat |
| A Biegon, B S McEwe. Modulation by estradiol of serotonin receptors in brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 2. 1982-05-21. PMID:7199565. |
estrogens were found to exert a biphasic effect on the density of serotonin receptors in the female rat brain: an acute reduction in serotonin receptor density throughout the brain is followed 48 to 72 hr later by a selective increase in those brain regions known to contain estrogen receptors--hypothalamus, preoptic area, and amygdala. |
1982-05-21 |
2023-08-12 |
rat |
| R Takahashi, T Tateishi, H Yoshida, H Nagayama, K H Tachik. Serotonin metabolism of animal model of depression. Advances in experimental medicine and biology. vol 133. 1982-02-12. PMID:6172020. |
all results presented here would indicate that serotonin plays an important role in animal behavior such as locomotor depression and that, taking into consideration the effects of antidepressants on 5-ht receptor activity as well as recent biochemical findings of human depression, some forms of human depression could be induced by a cerebral serotonergic receptor hyperactivity contrary to a conventional theory of serotonin deficiency in the synaptic cleft in the brain. |
1982-02-12 |
2023-08-12 |
human |
| S R Coughlin, M A Moskowitz, H N Antoniades, L Levin. Serotonin receptor-mediated stimulation of bovine smooth muscle cell prostacyclin synthesis and its modulation by platelet-derived growth factor. Proceedings of the National Academy of Sciences of the United States of America. vol 78. issue 11. 1982-02-12. PMID:7031670. |
an increase in prostacyclin synthesis was elicited by the addition of a serotonin agonist, quipazine (1 microm and above), and antagonized by the serotonin receptor blockers cyproheptadine, methysergide, or methiothepin but not by other aminergic receptor-blocking drugs (e.g., phentolamine or propranolol). |
1982-02-12 |
2023-08-12 |
cattle |
| C De Montign. Enhancement of the 5-HT neurotransmission by antidepressant treatments. Journal de physiologie. vol 77. issue 2-3. 1981-12-22. PMID:6270317. |
however, chronic administration of a new antidepressant drug, zimelidine, a potent and long-lasting 5-ht uptake blocker, fails to modify 5-ht receptor sensitivity. |
1981-12-22 |
2023-08-12 |
human |
| R D Myer. Serotonin and thermoregulation: old and new views. Journal de physiologie. vol 77. issue 2-3. 1981-12-22. PMID:6793718. |
new observations are described which show that 5-ht may elicit a fall in temperature as a result of the: (1) overloading of 5-ht receptor sites in the anterior hypothalamus; and/or (2) occupation by 5-ht of either noradrenergic or dopaminergic receptors, or both classes of catecholamine receptors which are believed to mediate the hypothalamic pathways for heat loss. |
1981-12-22 |
2023-08-12 |
rat |