| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tin-Tin Win-Shwe, Chaw Kyi-Tha-Thu, Yuji Fujitani, Shinji Tsukahara, Seishiro Hiran. Perinatal Exposure to Diesel Exhaust-Origin Secondary Organic Aerosol Induces Autism-Like Behavior in Rats. International journal of molecular sciences. vol 22. issue 2. 2021-03-30. PMID:33430368. |
serotonin receptor (5-ht(5b)) and brain-derived neurotrophic factor (bdnf) mrnas were downregulated whereas interleukin 1 β (il-β) and heme oxygenase 1 (ho-1) mrnas were upregulated in the prefrontal cortex of male and female rats exposed to de-soa. |
2021-03-30 |
2023-08-13 |
rat |
| Zhuo Wang, Chen Li, Jiuyang Ding, Yanning Li, Zhihua Zhou, Yanjun Huang, Xiaohan Wang, Haoliang Fan, Jian Huang, Yitong He, Jianwei Li, Jun Chen, Pingming Qi. Basolateral Amygdala Serotonin 2C Receptor Regulates Emotional Disorder-Related Symptoms Induced by Chronic Methamphetamine Administration. Frontiers in pharmacology. vol 12. 2021-02-26. PMID:33628192. |
alterations in both 5-ht and 5-ht receptor levels occurred simultaneously in bla; quantitative polymerase chain reaction, western blotting, and fluorescence analysis revealed that the expression of the 5-ht2c receptor (5-ht |
2021-02-26 |
2023-08-13 |
mouse |
| Aida Iraji, Mahsima Khoshneviszadeh, Omidreza Firuzi, Mehdi Khoshneviszadeh, Najmeh Edrak. Novel small molecule therapeutic agents for Alzheimer disease: Focusing on BACE1 and multi-target directed ligands. Bioorganic chemistry. vol 97. 2021-02-22. PMID:32101780. |
this article also highlights descriptions on the regulator of serotonin receptor (5-ht), metal chelators, anti-aggregants, antioxidants and neuroprotective agents targeting ad. |
2021-02-22 |
2023-08-13 |
Not clear |
| Kazuhiro Mio, Masaki Ishihara, Shoko Fujimura, Daisuke Sasaki, Shunsuke Nozawa, Kohei Ichiyanagi, Ryo Fukaya, Shin-Ichi Adachi, Masahiro Kuramochi, Hiroshi Sekiguchi, Tai Kubo, Yuji C Sasak. X-ray-based living-cell motion analysis of individual serotonin receptors. Biochemical and biophysical research communications. vol 529. issue 2. 2021-02-12. PMID:32703428. |
serotonin receptor subtype 2a (5-ht |
2021-02-12 |
2023-08-13 |
Not clear |
| Sophia Khom, Sarah A Wolfe, Reesha R Patel, Dean Kirson, David M Hedges, Florence P Varodayan, Michal Bajo, Marisa Robert. Alcohol Dependence and Withdrawal Impair Serotonergic Regulation of GABA Transmission in the Rat Central Nucleus of the Amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 36. 2021-01-01. PMID:32769108. |
the cea receives dense innervation from the dorsal raphe nucleus, the major source of 5-ht, and expresses 5-ht receptor subtypes (e.g., 5-ht2c and 5-ht1a) critically linked to alcohol use disorder. |
2021-01-01 |
2023-08-13 |
rat |
| Jitka Hromádková, Yutaka Suzuki, Sarah Pletts, Jade Pyo, Tao Ma, Yanhong Chen, Michael A Steele, Le Luo Gua. Effect of colostrum feeding strategies on the expression of neuroendocrine genes and active gut mucosa-attached bacterial populations in neonatal calves. Journal of dairy science. vol 103. issue 9. 2020-12-30. PMID:32622610. |
in addition, cf upregulated the expression of htr4 (serotonin receptor) and slc4a4 (serotonin transporter) genes in the ileum and increased the abundance of active lactobacillus spp. |
2020-12-30 |
2023-08-13 |
Not clear |
| Ryota Sakai, Kyoko Komai, Mana Iizuka-Koga, Akihiko Yoshimura, Minako It. Regulatory T Cells: Pathophysiological Roles and Clinical Applications. The Keio journal of medicine. vol 69. issue 1. 2020-12-29. PMID:31353330. |
brain tregs resemble other tissue tregs, but are unique in expressing neural cell-specific genes such as the serotonin receptor (htr7); consequently, brain tregs respond to serotonin. |
2020-12-29 |
2023-08-13 |
Not clear |
| Christian M Gallardo, Camille S Martin, Andrew D Steel. Food Anticipatory Activity on Circadian Time Scales Is Not Dependent on Central Serotonin: Evidence From Tryptophan Hydroxylase-2 and Serotonin Transporter Knockout Mice. Frontiers in molecular neuroscience. vol 13. 2020-12-15. PMID:33041772. |
several studies have implicated serotonin as a negative regulator of faa: (1) aged rats treated with serotonin 5-ht2 and 3 receptor antagonists showed enhanced faa, (2) mice lacking for the 2c serotonin receptor demonstrate enhanced faa, and (3) pharmacologically increased serotonin levels suppressed faa while decreased serotonin levels enhanced faa in mice. |
2020-12-15 |
2023-08-13 |
mouse |
| Manfred Göthert, Heinz Bönisch, Barbara Malinowska, Eberhard Schlicke. Serotonin discovery and stepwise disclosure of 5-HT receptor complexity over four decades. Part II. Some contributions of Manfred Göthert. Pharmacological reports : PR. vol 72. issue 2. 2020-11-27. PMID:32048263. |
serotonin discovery and stepwise disclosure of 5-ht receptor complexity over four decades. |
2020-11-27 |
2023-08-13 |
Not clear |
| Manfred Göthert, Heinz Bönisch, Barbara Malinowska, Eberhard Schlicke. Serotonin discovery and stepwise disclosure of 5-HT receptor complexity over four decades. Part II. Some contributions of Manfred Göthert. Pharmacological reports : PR. vol 72. issue 2. 2020-11-27. PMID:32048263. |
he was not only the witness of the gradual definition of the fourteen 5-ht receptor subtypes but also was involved directly by identifying 5-ht |
2020-11-27 |
2023-08-13 |
Not clear |
| Fernando E Padovan-Neto, Santanna Patterson, Nivea M F Voelkner, Feras Altwal, Joel A Beverley, Anthony R West, Heinz Steine. Selective Regulation of 5-HT1B Serotonin Receptor Expression in the Striatum by Dopamine Depletion and Repeated L-DOPA Treatment: Relationship to L-DOPA-Induced Dyskinesias. Molecular neurobiology. vol 57. issue 2. 2020-11-05. PMID:31468338. |
to further investigate the effects of dopamine and agonists on 5-ht receptors, we assessed the expression of 5-ht1b and other serotonin receptor subtypes in the striatum after unilateral dopamine depletion by 6-ohda and subsequent treatment with l-dopa (5 mg/kg; 4 weeks). |
2020-11-05 |
2023-08-13 |
Not clear |
| He-Fei Li, Jun-Feng Liu, Ke Zhang, Yong Fen. Expression of serotonin receptors in human lower esophageal sphincter. Experimental and therapeutic medicine. vol 9. issue 1. 2020-10-01. PMID:25452775. |
the aim of this study was to explore the expression of multiple types of 5-ht receptor (5-ht |
2020-10-01 |
2023-08-13 |
human |
| Nadine Herr, Christoph Bode, Daniel Duerschmie. The Effects of Serotonin in Immune Cells. Frontiers in cardiovascular medicine. vol 4. 2020-10-01. PMID:28775986. |
the functions of serotonin are mediated by members of the 7 known mammalian serotonin receptor subtype classes (15 known subtypes), the serotonin transporter (sert), and by covalent binding of serotonin to different effector proteins. |
2020-10-01 |
2023-08-13 |
Not clear |
| Dasiel O Borroto-Escuela, Xiang Li, Alexander O Tarakanov, David Savelli, Manuel Narváez, Kirill Shumilov, Yuniesky Andrade-Talavera, Antonio Jimenez-Beristain, Bartosz Pomierny, Zaida Díaz-Cabiale, Riccardo Cuppini, Patrizia Ambrogini, Maria Lindskog, Kjell Fux. Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition. ACS omega. vol 2. issue 8. 2020-10-01. PMID:28920103. |
studies on serotonin-selective reuptake inhibitors have established that disturbances in the ascending 5-ht neuron systems and their 5-ht receptor subtypes and collateral networks to the forebrain contribute to the etiology of major depression and are targets for treatment. |
2020-10-01 |
2023-08-13 |
Not clear |
| Steffen Vogelgesang, Marcus Niebert, Anne M Bischoff, Swen Hülsmann, Till Manzk. Persistent Expression of Serotonin Receptor 5b Alters Breathing Behavior in Male MeCP2 Knockout Mice. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:29515365. |
mecp2-deficient mice, which recapitulate this breathing phenotype, show a dysregulated, persistent expression of g-protein-coupled serotonin receptor 5-ht |
2020-10-01 |
2023-08-13 |
mouse |
| Wanchao Yin, X Edward Zhou, Dehua Yang, Parker W de Waal, Meitian Wang, Antao Dai, Xiaoqing Cai, Chia-Ying Huang, Ping Liu, Xiaoxi Wang, Yanting Yin, Bo Liu, Yu Zhou, Jiang Wang, Hong Liu, Martin Caffrey, Karsten Melcher, Yechun Xu, Ming-Wei Wang, H Eric Xu, Yi Jian. Crystal structure of the human 5-HT Cell discovery. vol 4. 2020-10-01. PMID:29560272. |
crystal structure of the human 5-ht 5-hydroxytryptamine (5-ht, also known as serotonin) regulates many physiological processes through the 5-ht receptor family. |
2020-10-01 |
2023-08-13 |
human |
| Man Jin, Yali Mo, Kaisheng Ye, Mingxian Chen, Yi Liu, Cao H. Efficacy of serotonin receptor agonists in the treatment of functional dyspepsia: a meta-analysis. Archives of medical science : AMS. vol 15. issue 1. 2020-10-01. PMID:30697251. |
functional dyspepsia (fd) is typically treated with serotonin receptor (5-ht) agonists such as cisapride, mosapride, tegaserod and tandospirone citrate. |
2020-10-01 |
2023-08-13 |
Not clear |
| William J Scotton, Lisa J Hill, Adrian C Williams, Nicholas M Barne. Serotonin Syndrome: Pathophysiology, Clinical Features, Management, and Potential Future Directions. International journal of tryptophan research : IJTR. vol 12. 2020-10-01. PMID:31523132. |
it is characterised by a dose-relevant spectrum of clinical findings related to the level of free serotonin (5-hydroxytryptamine [5-ht]), or 5-ht receptor activation (predominantly the 5-ht |
2020-10-01 |
2023-08-13 |
Not clear |
| Andreas Walther, Christoph Peter, Nevin Yilmaz, Werner Schmidt, Eike Martin, Heinfried Schmid. Influence of serotonin-receptor antagonism on mast cell activation during endotoxemia. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 8. issue 3. 2020-09-30. PMID:12039647. |
conclusions: serotonin receptor antagonism using the 5-ht(1/2/7)-receptor antagonist methysergide or the 5-ht(2a)-receptor antagonist ketanserin reduces endotoxin-induced mast cell activation in-vivo, most probably via the 5-ht(2a)-receptor subtype. |
2020-09-30 |
2023-08-12 |
rat |
| A Ganesh Kumar, K Balamurugan, R Vijaya Raghavan, G Dharani, R Kirubagara. Studies on the antifungal and serotonin receptor agonist activities of the secondary metabolites from piezotolerant deep-sea fungus Mycology. vol 10. issue 2. 2020-09-30. PMID:31069123. |
studies on the antifungal and serotonin receptor agonist activities of the secondary metabolites from piezotolerant deep-sea fungus the potent antifungal agent sesquiterpenes and serotonin 5-ht |
2020-09-30 |
2023-08-13 |
Not clear |