| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takashi Shiroyama, Kouji Fukuyama, Motohiro Okad. Distinct Effects of Escitalopram and Vortioxetine on Astroglial L-Glutamate Release Associated with Connexin43. International journal of molecular sciences. vol 22. issue 18. 2021-11-01. PMID:34576176. |
therefore, to explore the effects of antidepressants on transmission associated with astrocytes, the present study determined the effects of the selective 5-ht transporter inhibitor, escitalopram, and the 5-ht partial agonist reuptake inhibitor, vortioxetine, on astroglial l-glutamate release through activated hemichannels, and the expression of connexin43 (cx43), type 1a (5-ht1ar) and type 7 (5-ht7r) 5-ht receptor subtypes, and extracellular signal-regulated kinase (erk) in astrocytes using primary cultured rat cortical astrocytes in a 5-ht-free environment. |
2021-11-01 |
2023-08-13 |
rat |
| Luisa Ugedo, Philippe De Deurwaerdèr. Serotonergic control of the glutamatergic neurons of the subthalamic nucleus. Progress in brain research. vol 261. 2021-10-22. PMID:33785138. |
the effect of 5-ht on stn neuronal activity involves several 5-ht receptor subtypes, including 5-ht |
2021-10-22 |
2023-08-13 |
Not clear |
| Emiri Tarbit, Indu Singh, Jason Nigel Peart, Svetlana Bivol, Roselyn Barbara Rose'Meye. Increased release of serotonin from rat primary isolated adult cardiac myofibroblasts. Scientific reports. vol 11. issue 1. 2021-10-22. PMID:34645867. |
this is one of the first studies that has investigated serotonin receptors and other proteins involved in the serotonin receptor system in rat cardiac fibroblast and myofibroblast cells. |
2021-10-22 |
2023-08-13 |
rat |
| Keita Koizumi, Hideo Nakajim. Serotonin induces the migration of PC12 cells via the serotonin receptor 6/cAMP/ERK pathway. Biomedical reports. vol 2. issue 1. 2021-10-21. PMID:24649064. |
serotonin induces the migration of pc12 cells via the serotonin receptor 6/camp/erk pathway. |
2021-10-21 |
2023-08-12 |
Not clear |
| Keita Koizumi, Hideo Nakajim. Serotonin induces the migration of PC12 cells via the serotonin receptor 6/cAMP/ERK pathway. Biomedical reports. vol 2. issue 1. 2021-10-21. PMID:24649064. |
additionally, 5-ht receptor antagonists suggest that 5-ht-induced migration was mediated by serotonin receptor 6 (5-ht |
2021-10-21 |
2023-08-12 |
Not clear |
| Mark C Lloyd, Nancy Burke, Fatemeh Kalantarpour, Melissa I Niesen, Aaron Hall, Keith Pennypacker, Bruce Citron, Chaim G Pick, Vernard Adams, Mahasweta Das, Shyam Mohapatra, Hernani Cualing, George Blanc. QUANTITATIVE MORPHOLOGICAL AND MOLECULAR PATHOLOGY OF THE HUMAN THYMUS CORRELATE WITH INFANT CAUSE OF DEATH. Technology and innovation. vol 16. issue 1. 2021-10-21. PMID:25309682. |
finally, we determined that thymus expression of the human serotonin receptor, and the serotonin transporter, occur almost exclusively in the thymic medulla. |
2021-10-21 |
2023-08-13 |
mouse |
| Nimish Vakil, Farid Kianifard, Ivan Bottol. Exploratory Study of Tegaserod for Dyspepsia in Women Receiving PPIs for Heartburn. Archives of drug information. vol 1. issue 3. 2021-10-20. PMID:19639028. |
background and aims: tegaserod is a selective serotonin receptor (5-ht(4)) agonist that relieves dysmotility symptoms associated with constipation. |
2021-10-20 |
2023-08-12 |
Not clear |
| Genisson R Santos, Laise P A Chiari, Aldineia P da Silva, Célio F Lipinski, Aline A Oliveira, Kathia M Honorio, Alexsandro Gama de Sousa, Albérico B F da Silv. A partial least squares and artificial neural network study for a series of arylpiperazines as antidepressant agents. Journal of molecular modeling. vol 27. issue 10. 2021-10-12. PMID:34558019. |
5-ht receptor, known as serotonin, is considered the key in depression treatment. |
2021-10-12 |
2023-08-13 |
Not clear |
| Yéssica P López-Echeverri, Kelly J Cardona-Londoño, Jhonny F Garcia-Aguirre, Mary Orrego-Cardoz. Effects of Serotonin Transporter and Receptor Polymorphisms on Depression. Revista Colombiana de psiquiatria (English ed.). 2021-10-07. PMID:34493397. |
serotonin is highly implicated in the regulation of emotional state and the execution of cognitive tasks, so much so that the serotonin transporter genes (5-htt, slc6a4) and the serotonin receptor genes (htr1a, htr1b, htr2a) have become the perfect candidates when studying the effects that these genes and their polymorphic variations have on depression characteristics. |
2021-10-07 |
2023-08-13 |
Not clear |
| Sijie Huang, Peiyu Xu, Yangxia Tan, Chongzhao You, Yumu Zhang, Yi Jiang, H Eric X. Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT Cell research. vol 31. issue 9. 2021-10-02. PMID:34239069. |
structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-ht |
2021-10-02 |
2023-08-13 |
Not clear |
| Amber N Edinoff, Juliana M Fort, Joshua J Woo, Christopher D Causey, Caroline R Burroughs, Elyse M Cornett, Adam M Kaye, Alan D Kay. Selective Serotonin Reuptake Inhibitors and Clozapine: Clinically Relevant Interactions and Considerations. Neurology international. vol 13. issue 3. 2021-10-02. PMID:34564289. |
the preferential targeting of serotonin receptor (sert) by selective serotonin reuptake inhibitors (ssris) has offered an opportunity to reduce the range of these side effects and improve patient adherence to pharmacotherapy. |
2021-10-02 |
2023-08-13 |
Not clear |
| Chen-Xin Li, Ying Zheng, Hong Zhu, Cheng-Wu Li, Zhang He, Cong Wang, Jian-Hua Ding, Gang Hu, Ming L. β-arrestin 2 is essential for fluoxetine-mediated promotion of hippocampal neurogenesis in a mouse model of depression. Acta pharmacologica Sinica. vol 42. issue 5. 2021-09-27. PMID:33526871. |
emerging evidence suggests that fluoxetine can directly combine with the 5-ht receptor, which is a member of the g protein-coupled receptor (gpcr) family, in addition to suppressing the serotonin transporter. |
2021-09-27 |
2023-08-13 |
mouse |
| Yang Yang, Lijing Zhang, Jiaojiao Yu, Zhaobin Ma, Moxiang Li, Jin Wang, Pengcheng Hu, Jia Zou, Xueying Liu, Ying Liu, Su An, Cheng Xiang, Xiaoxi Guo, Qian Hao, Tian-Rui X. A Novel 5-HT Frontiers in pharmacology. vol 12. 2021-09-25. PMID:34552493. |
a novel 5-ht the serotonin receptor 5-ht |
2021-09-25 |
2023-08-13 |
Not clear |
| April Contreras, Matthew Khumnark, Rochelle M Hines, Dustin J Hine. Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT Scientific reports. vol 11. issue 1. 2021-09-23. PMID:33479368. |
behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-ht perception, emotion, and mood are powerfully modulated by serotonin receptor (5-htr) agonists including hallucinogens. |
2021-09-23 |
2023-08-13 |
Not clear |
| Dan Domocos, Tudor Selescu, Laura Cristina Ceafalan, Mirela Iodi Carstens, Earl Carstens, Alexandru Babe. Role of 5-HT1A and 5-HT3 receptors in serotonergic activation of sensory neurons in relation to itch and pain behavior in the rat. Journal of neuroscience research. vol 98. issue 10. 2021-09-17. PMID:32537854. |
using a combination of in vitro (calcium and voltage imaging and patch-clamp) and in vivo behavioral methods, we used both male and female wistar rats to provide evidence for the involvement of two 5-ht receptor subtypes, 5-ht1a and 5-ht3, in mediating the sustained and transient effects, respectively, of 5-ht on rat primary afferent neurons involved in pain and itch processing. |
2021-09-17 |
2023-08-13 |
rat |
| Zahid Parvez Sukhan, Yusin Cho, Md Rajib Sharker, Shaharior Hossen, Sung-Ju Rha, Kang Hee Kh. Effective accumulative temperature affects gonadal maturation by controlling expression of GnRH, GnRH receptor, serotonin receptor and APGWamide gene in Pacific abalone, Haliotis discus hannai during broodstock conditioning in hatcheries. Journal of thermal biology. vol 100. 2021-09-10. PMID:34503784. |
to understand the molecular mechanism underlying the regulation of gonadal maturation and reproduction of haliotis discus hannai exposed to eat and induced spawning period, changes in expression of neuroendocrine genes encoding two gonadotropin releasing hormone (hdh-gnrh, gnrh-like peptide), gnrh receptor (hdhgnrh-r), serotonin receptor (5-ht |
2021-09-10 |
2023-08-13 |
Not clear |
| Caiyun Sun, Yang Qiu, Qin Ren, Xiao Zhang, Baolong Cao, Yi Zou, Juan Li, Jiannan Zhang, Yajun Wan. Molecular Cloning and Functional Characterization of Three 5-HT Receptor Genes ( Genes. vol 12. issue 6. 2021-08-27. PMID:34207786. |
molecular cloning and functional characterization of three 5-ht receptor genes ( the serotonin (5-hydroxytryptamine, 5-ht) signaling system is involved in a variety of physiological functions, including the control of cognition, reward, learning, memory, and vasoconstriction in vertebrates. |
2021-08-27 |
2023-08-13 |
Not clear |
| Marie Hagbom, Arash Hellysaz, Claudia Istrate, Johan Nordgren, Sumit Sharma, Felipe Meira de-Faria, Karl-Eric Magnusson, Lennart Svensso. The 5-HT Journal of virology. vol 95. issue 15. 2021-08-25. PMID:33980599. |
serotonin is released during rotavirus infection, and antagonists to the serotonin receptor subtype 3 (5-ht |
2021-08-25 |
2023-08-13 |
Not clear |
| Cory A Massey, Samantha J Thompson, Ryan W Ostrom, Janice Drabek, Olafur A Sveinsson, Torbjörn Tomson, Elisabeth A Haas, Othon J Mena, Alica M Goldman, Jeffrey L Noebel. X-linked serotonin 2C receptor is associated with a non-canonical pathway for sudden unexpected death in epilepsy. Brain communications. vol 3. issue 3. 2021-08-17. PMID:34396109. |
accordingly, the g protein-coupled, membrane serotonin receptor 5-ht |
2021-08-17 |
2023-08-13 |
mouse |
| Trevor Sharp, Nicholas M Barne. Central 5-HT receptors and their function; present and future. Neuropharmacology. vol 177. 2021-08-12. PMID:32522572. |
since our review of central 5-ht receptors and their function twenty years ago, no new 5-ht receptor has been discovered and there is little evidence that this situation will change in the near future. |
2021-08-12 |
2023-08-13 |
human |