| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xusheng Dong, Chen Liu, Jialin Miao, Xueyan Lin, Yun Wang, Zhonghua Wang, Qiuling Ho. Effect of serotonin on the cell viability of the bovine mammary alveolar cell-T (MAC-T) cell line. Journal of animal science and technology. vol 64. issue 5. 2022-10-26. PMID:36287778. |
the results suggested that 20 μm 5-ht treatment for 12 or 24 h promote cell viability, which was mainly induced by the activation of 5-ht receptor (5-htr) 1b and 4, because the increase caused by 5-ht vanished when 5-htr 1b and 4 was blocked by sb224289 and sb204070. |
2022-10-26 |
2023-08-14 |
cattle |
| Ria Gupta, Sidharth Mehan, Swesha Chhabra, Aditi Giri, Kajal Sherawa. Role of Sonic Hedgehog Signaling Activation in the Prevention of Neurological Abnormalities Associated with Obsessive-Compulsive Disorder. Neurotoxicity research. 2022-10-22. PMID:36272053. |
the shh ligand activates two main transcriptional factors known as foxa2 and nkx2.2, which again activates another transcriptional factor, gata (gata2 and gata3), in post mitotic precursor cells of serotonergic neurons-following increased expression of pet-1 and lmx1b after gata regulates the expression of many serotonergic enzymes such as tph2, sert, vmat, slc6a4, htr1a, htr1b (serotonin receptor enzymes), and mao that regulate and control the release of serotonin and maintain their neuronal identity after their maturation. |
2022-10-22 |
2023-08-14 |
Not clear |
| Bo Qiu, Lian Zhu, Shuobo Zhang, Shengyi Han, Yiqiu Fei, Furong Ba, Björn Berglund, Lanjuan Li, Mingfei Ya. Prevention of Loperamide-Induced Constipation in Mice and Alteration of 5-Hydroxytryotamine Signaling by Nutrients. vol 14. issue 19. 2022-10-17. PMID:36235735. |
li01 also promoted the expression of 5-ht receptor 3 and 4, indicating that the 5-ht signaling pathway may play a critical role in the mechanism by which li01 alleviate constipation symptoms. |
2022-10-17 |
2023-08-16 |
mouse |
| Bernardo Lopez-Torres, Irma Ares, Marta Martínez, Jorge-Enrique Maximiliano, María-Rosa Martínez-Larrañaga, Arturo Anadón, María-Aránzazu Martíne. Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022-09-20. PMID:36126889. |
this research study also showed in hippocampus and prefrontal cortex, that lambda-cyhalothrin modified the mrna levels of da transporter gene (dat1 up-regulation), 5-ht transporter gene (sert down-regulation), da receptor genes (drd1and drd2 down-regulation), 5-ht receptor genes (5-ht1a and 5-ht2a down-regulation/up-regulation), da synthesis gene (th down-regulation), 5-ht synthesis gene (tph2 down-regulation), da and 5-ht degradation genes (maoa and maob up-regulation). |
2022-09-20 |
2023-08-14 |
rat |
| Doo Ri Park, Chang Hwan Yeo, Jee Eun Yoon, Eun Young Hong, Bo Ram Choi, Yoon Jae Lee, In-Hyuk H. Polygonatum sibiricum improves menopause symptoms by regulating hormone receptor balance in an ovariectomized mouse model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 153. 2022-09-09. PMID:36076523. |
ps restored vaginal epithelium thickness, by increasing the expression of estrogen receptors erα (esr1) and erβ (esr2), and increased serotonin concentration by reducing serotonin receptor 1 a (5-ht1a) and glucocorticoid receptor (gr) expression. |
2022-09-09 |
2023-08-14 |
mouse |
| Shu-Hsien Sheu, Srigokul Upadhyayula, Vincent Dupuy, Song Pang, Fei Deng, Jinxia Wan, Deepika Walpita, H Amalia Pasolli, Justin Houser, Silvia Sanchez-Martinez, Sebastian E Brauchi, Sambashiva Banala, Melanie Freeman, C Shan Xu, Tom Kirchhausen, Harald F Hess, Luke Lavis, Yulong Li, Séverine Chaumont-Dubel, David E Clapha. A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility. Cell. vol 185. issue 18. 2022-09-02. PMID:36055200. |
functionally, these cilia are enriched in a ciliary-restricted serotonin receptor, the 5-hydroxytryptamine receptor 6 (5-htr6). |
2022-09-02 |
2023-08-14 |
Not clear |
| Isadora Braga Contreiras Carneiro, Ana Elisa Toscano, Marcela de Sá Barreto da Cunha, Diego Cabral Lacerda, Paula Brielle Pontes, Raul Manhães de Castro, Tereza Cristina Bonfim de Jesus Deiró, Jairza Maria Barreto Medeiro. Serotonergic mechanisms associated with experimental models of hypoxia: a systematic review. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-08-23. PMID:35996828. |
the aim of this systematic review was to explore and discuss the literature concerning the effects of hypoxia or anoxia during the perinatal period on the serotoninergic network in rodents, through mechanisms that lead to changes in serotonergic neurons, serotonin(5-ht) and 5-hydroxyindole amino acid (5-hiaa) levels, segments of central nervous system affected, 5-ht transporter and 5-ht receptor. |
2022-08-23 |
2023-08-14 |
Not clear |
| Tatiana Ilchibaeva, Anton Tsybko, Andre Zeug, Franziska E Müller, Daria Guseva, Stephan Bischoff, Evgeni Ponimaskin, Vladimir Naumenk. Serotonin Receptor 5-HT Cells. vol 11. issue 15. 2022-08-12. PMID:35954229. |
serotonin receptor 5-ht serotonin receptor 5-ht |
2022-08-12 |
2023-08-14 |
Not clear |
| Anna Szurpnicka, Anna Katarzyna Wrońska, Katarzyna Bus, Aleksandra Kozińska, Renata Jabłczyńska, Arkadiusz Szterk, Katarzyna Lubelsk. Phytochemical screening and effect of Viscum album L. on monoamine oxidase A and B activity and serotonin, dopamine and serotonin receptor 5-HTR1A levels in Galleria mellonealla (Lepidoptera). Journal of ethnopharmacology. 2022-08-09. PMID:35944736. |
phytochemical screening and effect of viscum album l. on monoamine oxidase a and b activity and serotonin, dopamine and serotonin receptor 5-htr1a levels in galleria mellonealla (lepidoptera). |
2022-08-09 |
2023-08-14 |
Not clear |
| Natosha M Mercado, Guanglin Zhang, Zhe Ying, Fernando Gómez-Pinill. Traumatic brain injury alters the gut-derived serotonergic system and associated peripheral organs. Biochimica et biophysica acta. Molecular basis of disease. 2022-07-28. PMID:35902006. |
there also was a decrease in serotonin fluorescence intensity in the colonic mucosa and reduced circulating blood serotonin levels, with concurrent alterations in serotonin-associated gene expression in downstream tissues after tbi (i.e., upregulation of serotonin receptor htr2a and dysregulation of genes associated with lipid metabolism in liver and adipose). |
2022-07-28 |
2023-08-14 |
mouse |
| Reza Rajabalizadeh, Mahboobeh Ghasemzadeh Rahbardar, Hossein Hosseinzade. Medicinal herbs in treating chemotherapy-induced nausea and vomiting: A review. Phytotherapy research : PTR. 2022-07-16. PMID:35841194. |
in this manuscript, the antiemetic mechanisms of several herbal medicines and their preparations such as zingiber officinale (5-ht, nk-1 receptor and muscarinic antagonist activity), mentha spicata (5-ht antagonist activity), scutellaria baicalensis (antioxidant activity), persumac (useful in delayed phase through antioxidant, anti-inflammatory, and anti-contractile properties) and rikkunshito (supportive in acute and delayed phase through 5-ht receptor antagonist activity) have been reviewed to show their potential effects on decreasing cinv and attract scientists attention to formulate more herbal medicine to alleviate cinv in cancer patients. |
2022-07-16 |
2023-08-14 |
Not clear |
| Keaton A Unroe, Jessica L Maltman, Elizabeth A Shupe, Sarah M Clinto. Disrupted serotonin system development via early life antidepressant exposure impairs maternal care and increases serotonin receptor expression in adult female offspring. Developmental psychobiology. vol 64. issue 6. 2022-06-24. PMID:35748633. |
these results demonstrate that early alterations to 5-ht signaling through ssri exposure may disrupt nurturing parental behaviors and 5-ht receptor expression in affected female rat offspring. |
2022-06-24 |
2023-08-14 |
rat |
| Minhee Kim, Wonil Choi, Jihyeon Yoon, Byung-Kwan Jeong, Suvarna H Pagire, Haushabhau S Pagire, Jungsun Park, Jung Eun Nam, Chang Joo Oh, Jae-Han Jeon, Seong Soon Kim, Byung Hoi Lee, Jin Sook Song, Myung Ae Bae, In-Kyu Lee, Hail Kim, Jin Hee Ah. Synthesis and biological evaluation of tyrosine derivatives as peripheral 5HT European journal of medicinal chemistry. vol 239. 2022-06-22. PMID:35732081. |
among serotonin receptor subtypes, 5ht |
2022-06-22 |
2023-08-14 |
Not clear |
| Amber N Edinoff, Juliana M Fort, Christina Singh, Sarah E Wagner, Jessica R Rodriguez, Catherine A Johnson, Elyse M Cornett, Kevin S Murnane, Adam M Kaye, Alan D Kay. Alternative Options for Complex, Recurrent Pain States Using Cannabinoids, Psilocybin, and Ketamine: A Narrative Review of Clinical Evidence. Neurology international. vol 14. issue 2. 2022-06-01. PMID:35645354. |
psilocybin, commonly known as "magic mushrooms", works at the serotonin receptor, 5-ht |
2022-06-01 |
2023-08-13 |
Not clear |
| Emanuela Dyrmishi, Marco De Pieri, Marco Ferrari, Rafael Traber, Matteo Preve, Luca De Peri, Emilio Boll. Case Report: Long-Acting Oral Cariprazine. Frontiers in psychiatry. vol 13. 2022-05-16. PMID:35573352. |
cariprazine is a partial agonist at dopamine receptors d2 and d3 and serotonin receptor 5ht1a and an antagonist at serotonin receptors 5ht2b and 5ht2a. |
2022-05-16 |
2023-08-13 |
Not clear |
| Nina M Beltran, Jeremiah Ramos, Antonio Landavazo, Bruce Blough, Katherine M Serafin. Eating a High Fat Diet Enhances Sensitivity of Rats to 5-HT FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555947. |
to test the hypothesis that eating a high fat diet enhances sensitivity of rats to 5-ht syndrome, male (n=16) and female (n=16) rats eating high fat (60% kcal from fat) or standard (17% kcal from fat) laboratory chow were tested once weekly with cumulative doses of 5-ht receptor agonists, including 8-oh-dpat (0.01-1.0 mg/kg, s.c.), lorcaserin (1.0-32.0 mg/kg, i.p.) |
2022-05-13 |
2023-08-13 |
rat |
| Vinay K Sharma, Xuyu Yang, Soo-Kyung Kim, Amirhossain Maafi, Lan Xiao, Aska Inoue, William A Goddard, Y P Lo. 5HTR1E receptor interacts with Neurotrophic factor-α1 and serotonin to activate two distinct signaling pathways. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35557446. |
we have identified 5-hydroxytryptamine receptor 1e (5htr1e), a gi coupled serotonin receptor, as an extracellular binding partner of nfα1/cpe. |
2022-05-13 |
2023-08-13 |
Not clear |
| Elizabeth A Bartlett, Francesca Zanderigo, Denise Shieh, Jeffrey Miller, Patrick Hurley, Harry Rubin-Falcone, Maria A Oquendo, M Elizabeth Sublette, R Todd Ogden, J John Man. Serotonin transporter binding in major depressive disorder: impact of serotonin system anatomy. Molecular psychiatry. 2022-04-29. PMID:35487966. |
we now investigate 5-htt binding in mdd in two novel ways: (1) use of a 5-htt tract-based analysis examining binding along serotonergic axons; and (2) using the copenhagen university hospital neurobiology research unit (nru) 5-ht atlas, based on brain-wide binding patterns of multiple serotonin receptor types. |
2022-04-29 |
2023-08-13 |
Not clear |
| Ann Jane Tierney, Madelyn Haller, Leah Grossman, Hannah Grote, Natalie Marcus-Baue. Serotonergic modulation of appetitive and ingestive behavior in crayfish. Behavioral neuroscience. 2022-03-31. PMID:35357863. |
we examined the modulation of feeding behavior in crayfish by administering serotonin and two serotonin receptor ligands, mianserin and 5-carboxamidotryptamine. |
2022-03-31 |
2023-08-13 |
Not clear |
| Georg A Petroian. Hyperthermia and Serotonin: The Quest for a "Better Cyproheptadine". International journal of molecular sciences. vol 23. issue 6. 2022-03-25. PMID:35328784. |
based on the theoretical model presented the "ideal" antidote against serotonin syndrome hyperthermia appears to be an antagonist at the 5-ht receptor subtypes 2, 4 and 6 and an agonist at the receptor subtypes 1, 3 and 7. |
2022-03-25 |
2023-08-13 |
Not clear |