| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xin Wen, Xue Yu, Rong Huo, Qiu-Xin Yan, Di Wu, Yan Feng, Ying Li, Xun Sun, Xin-Yu Li, Jie Sun, Ke-Xin Li, Qing-Yuan Li, Li-Min Han, Xiao-Long Lu, Yang Liu, Weinian Shou, Bai-Yan L. Serotonin-Mediated Cardiac Analgesia via Ah-Type Baroreceptor Activation Contributes to Silent Angina and Asymptomatic Infarction. Neuroscience. vol 411. 2020-02-04. PMID:31153963. |
5-ht or a 5-ht receptor agonist was microinjected into the nodose ganglion to confirm the involvement of the afferent pathway of the baroreflex arc. |
2020-02-04 |
2023-08-13 |
rat |
| Guangchen Ji, Volker Neugebaue. Contribution of Corticotropin-Releasing Factor Receptor 1 (CRF1) to Serotonin Receptor 5-HT International journal of molecular sciences. vol 20. issue 18. 2020-02-04. PMID:31489921. |
contribution of corticotropin-releasing factor receptor 1 (crf1) to serotonin receptor 5-ht the amygdala plays a key role in emotional-affective aspects of pain and in pain modulation. |
2020-02-04 |
2023-08-13 |
Not clear |
| Nicky Staes, Chet C Sherwood, Hani Freeman, Sarah F Brosnan, Steven J Schapiro, William D Hopkins, Brenda J Bradle. Serotonin Receptor 1A Variation Is Associated with Anxiety and Agonistic Behavior in Chimpanzees. Molecular biology and evolution. vol 36. issue 7. 2020-01-30. PMID:31045220. |
polymorphisms in genes coding for the serotonin receptor subtype 1a (htr1a), the serotonin transporter (slc6a4), and the serotonin degrading enzyme monoamine oxidase a (maoa) are associated with anxiety, impulsivity, and neurotic personality in humans. |
2020-01-30 |
2023-08-13 |
Not clear |
| Muhammad Adnan Bashir, Arif-Ullah Khan, Haroon Badshah, Edson Rodrigues-Filho, Zia Ud Din, Aslam Kha. Synthesis, characterization, molecular docking evaluation, antidepressant, and anti-Alzheimer effects of dibenzylidene ketone derivatives. Drug development research. vol 80. issue 5. 2020-01-27. PMID:30964563. |
both a1k1 and a2k2 showed high binding affinities against various proteins involved in depression and alzheimer's mechanisms like monoamine oxidase b, acetylcholinesterase, norepinephrine transporter 2, serotonin transporter, dopamine receptor, serotonin receptor modulator, and beta-amyloid targets. |
2020-01-27 |
2023-08-13 |
mouse |
| Myrina Boulais, Marina Demoy-Schneider, Sayyed Mohammad Hadi Alavi, Jacky Cosso. Spermatozoa motility in bivalves: Signaling, flagellar beating behavior, and energetics. Theriogenology. vol 136. 2020-01-20. PMID:31234053. |
serotonin (5-ht) induces hyper-motility in spermatozoa via a 5-ht receptor, suggesting a serotoninergic system in the male reproductive tract that might regulate sperm physiology. |
2020-01-20 |
2023-08-13 |
Not clear |
| Kevin Sean Murnan. Serotonin 2A receptors are a stress response system: implications for post-traumatic stress disorder. Behavioural pharmacology. vol 30. issue 2 and 3-Spec Issue. 2020-01-06. PMID:30632995. |
the 2a subtype of serotonin receptors (5-ht2a receptor) is the major excitatory serotonin receptor in the brain and has been linked to the effects of drugs that produce profound sensory and cognitive changes. |
2020-01-06 |
2023-08-13 |
Not clear |
| Sandip Basak, Yvonne Gicheru, Abhijeet Kapoor, Megan L Mayer, Marta Filizola, Sudha Chakrapan. Molecular mechanism of setron-mediated inhibition of full-length 5-HT Nature communications. vol 10. issue 1. 2019-12-11. PMID:31324772. |
molecular mechanism of setron-mediated inhibition of full-length 5-ht serotonin receptor (5-ht |
2019-12-11 |
2023-08-13 |
Not clear |
| Ling-Ling Teng, Guan-Ling Lu, Lih-Chu Chiou, Wei-Sheng Lin, Ya-Yun Cheng, Tai-En Hsueh, Yi-Ching Huang, Nai-Hsuan Hwang, Jin-Wei Yeh, Ruey-Ming Liao, Shou-Zen Fan, Jui-Hung Yen, Tsai-Feng Fu, Ting-Fen Tsai, Ming-Shiang Wu, Pei-Yu Wan. Serotonin receptor HTR6-mediated mTORC1 signaling regulates dietary restriction-induced memory enhancement. PLoS biology. vol 17. issue 3. 2019-11-25. PMID:30883547. |
we have explored the molecular mechanism of dr-induced memory enhancement and demonstrate that dietary tryptophan-a precursor amino acid for serotonin biosynthesis in the brain-and serotonin receptor 5-hydroxytryptamine receptor 6 (htr6) are crucial in mediating this process. |
2019-11-25 |
2023-08-13 |
Not clear |
| Winberg, Nilsso. Multiple high-affinity binding sites for The Journal of experimental biology. vol 199. issue Pt 11. 2019-11-20. PMID:9320352. |
the ability of a number of synthetic 5-ht receptor ligands to displace [3h]5-ht was studied. |
2019-11-20 |
2023-08-12 |
Not clear |
| Versen, Gokorsch, Fiedler, Schip. Monoamines and the isolated auricle of sepia officinalis: are there &bgr;-like receptors in the heart of a cephalopod? The Journal of experimental biology. vol 202 (Pt 9). 2019-11-20. PMID:10101106. |
it is assumed that the auricular serotonin (5-ht) receptor represents a 5-ht1-like subtype and is not identical to the ventricular 5-ht receptor. |
2019-11-20 |
2023-08-12 |
Not clear |
| B. Rocha, G. Di Scala, F. Jenck, J.-L. Moreau, G. Sandne. Conditioned place aversion induced by 5-HT(1C) receptor antagonists. Behavioural pharmacology. vol 4. issue 2. 2019-11-20. PMID:11224176. |
a place-conditioning procedure was used to investigate the affective properties in rats of non-selective serotonin receptor antagonists (mianserin, eltoprazine and ketanserin) differing from each other by their affinity for 5-ht(1c) and 5-ht(2) receptors among others. |
2019-11-20 |
2023-08-12 |
rat |
| A.K. Cadogan, D.A. Kendall, H. Fink, C.A. Marsde. Social interaction increases 5-HT release and cAMP efflux in the rat ventral hippocampus in vivo. Behavioural pharmacology. vol 5. issue 3. 2019-11-20. PMID:11224279. |
the results suggest that social interaction results in activation of a post-synaptic 5-ht receptor (5-ht(1a) or 5-ht(6)/5-ht(7)) coupled to adenylate cyclase but that this receptor is not responsible for the aversion-induced behaviour. |
2019-11-20 |
2023-08-12 |
rat |
| B. Bjorvatn, D. Neckelmann, A.A. Bjørkum, R. Ursi. Hypothermia and the 5-HT syndrome induced by CGS 12066B independently of 5-HT(1B) receptor activation. Behavioural pharmacology. vol 7. issue 5. 2019-11-20. PMID:11224442. |
the cgs 12066b-induced changes were not antagonized by 5-ht(1b) receptor antagonists, or antagonists at other 5-ht receptor. |
2019-11-20 |
2023-08-12 |
rat |
| C. Sánche. 5-HT(1A) receptors play an important role in modulation of behavior of rats in a two-compartment black and white box. Behavioural pharmacology. vol 7. issue 8. 2019-11-20. PMID:11224473. |
it is suggested that 5-ht(1a) and 5-ht(2c) receptors are involved in mediation of exploratory behavior in rats, and that the 5-ht receptor subtype mediated effects may modulate one another. |
2019-11-20 |
2023-08-12 |
rat |
| Kimberly L. Stark, René He. Knockout Corner. The international journal of neuropsychopharmacology. vol 2. issue 2. 2019-11-20. PMID:11281982. |
to date, there are 14 known serotonin receptor subtypes through which serotonin exerts its multiple actions. |
2019-11-20 |
2023-08-12 |
mouse |
| Klaus Peter Lesch, Armin Heil. Serotonergic gene transcriptional control regions: targets for antidepressant drug development? The international journal of neuropsychopharmacology. vol 3. issue 1. 2019-11-20. PMID:11343581. |
the formation and integration of neural networks is dependent on the actions of the master control neurotransmitter serotonin (5-ht) acting through multiple 5-ht receptor subtypes. |
2019-11-20 |
2023-08-12 |
Not clear |
| Caroline Flora Samer, Jules Alexandre Desmeules, Pierre Daye. Individualizing analgesic prescription Part I: pharmacogenetics of opioid analgesics. Personalized medicine. vol 3. issue 3. 2019-11-20. PMID:29788657. |
this two-part review summarizes the available data on the pharmacokinetic-pharmacodynamic consequences of known polymorphisms of drug-metabolizing enzymes (cyp and uridine diphosphate glucuronosyltransferase), drug transporters (multidrug resistance proteins, multidrug resistance-associated proteins, organic anion-transporting polypeptides, and serotonin transporters), relevant drug targets (such as µ-opioid receptor, serotonin receptor and cyclooxygenases) and other nonopioid biological systems, on currently prescribed central and peripheral analgesics. |
2019-11-20 |
2023-08-13 |
Not clear |
| Stefania Porcu, Stefania Demuro, Alberto Luridiana, Andrea Cocco, Angelo Frongia, David J Aitken, Florence Charnay-Pouget, Regis Guillot, Giorgia Sarais, Francesco Secc. Brønsted Acid Mediated Cascade Reaction To Access 3-(2-Bromoethyl)benzofurans. Organic letters. vol 20. issue 23. 2019-11-20. PMID:30422665. |
this mild and facile strategy was applied for the synthesis of a series of 5-ht serotonin receptor agonists, underlining its potential for the syntheses of bioactive compounds and natural products. |
2019-11-20 |
2023-08-13 |
Not clear |
| Yu-Jin Kwon, Kyung-Won Hong, Byung Jin Park, Dong-Hyuk Jun. Serotonin receptor 3B polymorphisms are associated with type 2 diabetes: The Korean Genome and Epidemiology Study. Diabetes research and clinical practice. vol 153. 2019-11-12. PMID:31152805. |
serotonin, or 5-hydroxytryptamine (5-ht), and serotonin receptor (htr) subtypes contribute to controlling energy homeostasis. |
2019-11-12 |
2023-08-13 |
Not clear |
| Meysam Amidfar, Yong-Ku Ki. Recent Developments on Future Antidepressant-related Serotonin Receptors. Current pharmaceutical design. vol 24. issue 22. 2019-11-06. PMID:30073919. |
however, paradoxical antidepressant-like effects of both agonists and antagonists at particular 5-ht receptors suggest the need to consider the neurochemical mechanisms of each 5-ht receptor subtype. |
2019-11-06 |
2023-08-13 |
Not clear |