| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Komorowski, G M James, C Philippe, G Gryglewski, A Bauer, M Hienert, M Spies, A Kautzky, T Vanicek, A Hahn, T Traub-Weidinger, D Winkler, W Wadsak, M Mitterhauser, M Hacker, S Kasper, R Lanzenberge. Association of Protein Distribution and Gene Expression Revealed by PET and Post-Mortem Quantification in the Serotonergic System of the Human Brain. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 1. 2018-01-15. PMID:27909009. |
pet binding values and gene expression intensities were correlated for the main inhibitory (5-ht1a) and excitatory (5-ht2a) serotonin receptor, the serotonin transporter (sert) as well as monoamine oxidase-a (mao-a), using spearman's correlation coefficients (rs) in a voxel-wise and region-wise analysis. |
2018-01-15 |
2023-08-13 |
human |
| Junfeng Yao, Xiaoliang Wang, Huangxiang Yan, Xia Cai, Min Wang, Yingying Tu, Changsuo Yan. Enhanced Expression of Serotonin Receptor 5-Hydroxytryptamine 2C is Associated with Increased Feather Damage in Dongxiang Blue-Shelled Layers. Behavior genetics. vol 47. issue 3. 2018-01-02. PMID:28275879. |
enhanced expression of serotonin receptor 5-hydroxytryptamine 2c is associated with increased feather damage in dongxiang blue-shelled layers. |
2018-01-02 |
2023-08-13 |
chicken |
| Estelle Louiset, Céline Duparc, Sébastien Lenglet, Celso E Gomez-Sanchez, Hervé Lefebvr. Role of cAMP/PKA pathway and T-type calcium channels in the mechanism of action of serotonin in human adrenocortical cells. Molecular and cellular endocrinology. vol 441. 2017-11-21. PMID:27743992. |
in human adrenal, serotonin (5-ht), produced by mast cells located in zona glomerulosa, stimulates production of corticosteroids through a paracrine mechanism involving the 5-ht receptor type 4 (5-ht |
2017-11-21 |
2023-08-13 |
human |
| Filip Tylš, Tomáš Páleníček, Lukáš Kadeřábek, Michaela Lipski, Anna Kubešová, Jiří Horáče. Sex differences and serotonergic mechanisms in the behavioural effects of psilocin. Behavioural pharmacology. vol 27. issue 4. 2017-11-20. PMID:26461483. |
the contribution of serotonin receptors in the behavioural action was tested in male rats with selective serotonin receptor antagonists: 5-ht1a receptor antagonist (way100635 1 mg/kg), 5-ht2a receptor antagonist (mdl100907 0.5 mg/kg), 5-ht2b receptor antagonist (sb215505 1 mg/kg) and 5-ht2c receptor antagonist (sb242084 1 mg/kg). |
2017-11-20 |
2023-08-13 |
rat |
| Matthias M Herth, Ida Nymann Petersen, Hanne Demant Hansen, Martin Hansen, Anders Ettrup, Anders A Jensen, Szabolcs Lehel, Agnete Dyssegaard, Nic Gillings, Gitte M Knudsen, Jesper L Kristense. Synthesis and evaluation of (18)F-labeled 5-HT2A receptor agonists as PET ligands. Nuclear medicine and biology. vol 43. issue 8. 2017-11-20. PMID:27209485. |
the serotonin 2a receptor (5-ht2ar) is the most abundant excitatory 5-ht receptor in the human brain and implicated in various brain disorders such as schizophrenia, depression, and alzheimer's disease. |
2017-11-20 |
2023-08-13 |
human |
| Kangjian Xiang, Xuefei Zhao, Youjun Li, Liang Zheng, Jue Wang, Yan-Hai L. Selective 5-HT7 Receptor Activation May Enhance Synaptic Plasticity Through N-methyl-D-aspartate (NMDA) Receptor Activity in the Visual Cortex. Current neurovascular research. vol 13. issue 4. 2017-10-19. PMID:27558200. |
serotonin (5-hydroxytryptamine, 5-ht) is an important neurotransmitter that modulates n-methyl-d-aspartate (nmda) receptor activity by binding to several different 5-ht receptor subtypes. |
2017-10-19 |
2023-08-13 |
rat |
| Susan Schenk, Dane Aronse. Contribution of Impulsivity and Serotonin Receptor Neuroadaptations to the Development of an MDMA ('Ecstasy') Substance Use Disorder. Current topics in behavioral neurosciences. vol 34. 2017-10-17. PMID:26718587. |
data from both the human and laboratory animal literature are synthesized to support the idea that (1) mdma becomes a less efficacious serotonin releaser and a more efficacious dopamine releaser with the development of behaviour consistent with an sud and (2) that upregulated serotonin receptor mechanisms contribute to the development of the mdma sud via dysregulated inhibitory control associated with the trait of impulsivity. |
2017-10-17 |
2023-08-13 |
human |
| Dina Ripken, Nikkie van der Wielen, Heleen M Wortelboer, Jocelijn Meijerink, Renger F Witkamp, Henk F J Hendrik. Nutrient-induced glucagon like peptide-1 release is modulated by serotonin. The Journal of nutritional biochemistry. vol 32. 2017-10-09. PMID:27142747. |
the central hypothesis for the current study was that nutrient-induced glp-1 release from eecs is modulated by serotonin through a process involving serotonin receptor interaction. |
2017-10-09 |
2023-08-13 |
Not clear |
| D J David, A M Gardie. [The pharmacological basis of the serotonin system: Application to antidepressant response]. L'Encephale. vol 42. issue 3. 2017-09-20. PMID:27112704. |
however, antidepressant activity of sert inhibitors is not directly mediated by the sert inhibition, but a consequence of postsynaptic 5-ht receptor activation following the increase in 5-ht levels in the synaptic cleft. |
2017-09-20 |
2023-08-13 |
Not clear |
| Thomas E Finger, Dianna L Bartel, Nicole Shultz, Noah B Goodson, Charles A Gree. 5HTR3A-driven GFP labels immature olfactory sensory neurons. The Journal of comparative neurology. vol 525. issue 7. 2017-09-15. PMID:28152579. |
the ionotropic serotonin receptor, 5-ht |
2017-09-15 |
2023-08-13 |
Not clear |
| Jin Ri Hong, Hyunah Choo, Ghilsoo Na. Neuropathic pain-alleviating effects of pyrazole-conjugated arylsulfonamides as 5-HT Bioorganic & medicinal chemistry letters. vol 27. issue 17. 2017-09-13. PMID:28729057. |
neuropathic pain-alleviating effects of pyrazole-conjugated arylsulfonamides as 5-ht a novel series of arylsulfonylaminomethyl-3-(1-phenyl-5-isopropyl)pyrazoles was evaluated for serotonin receptor subtype 6 (5-ht |
2017-09-13 |
2023-08-13 |
Not clear |
| Guangchen Ji, Wei Zhang, Lenin Mahimainathan, Madhusudhanan Narasimhan, Takaki Kiritoshi, Xiuzhen Fan, Jigong Wang, Thomas A Green, Volker Neugebaue. 5-HT The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 6. 2017-07-27. PMID:28011743. |
the cea receives excitatory and inhibitory inputs from the basolateral nucleus (bla) and serotonin receptor subtype 5-ht |
2017-07-27 |
2023-08-13 |
Not clear |
| Jemma L Trick, Sivapalan Chelvaniththilan, Gianni Klesse, Prafulla Aryal, E Jayne Wallace, Stephen J Tucker, Mark S P Sanso. Functional Annotation of Ion Channel Structures by Molecular Simulation. Structure (London, England : 1993). vol 24. issue 12. 2017-06-28. PMID:27866853. |
using the serotonin receptor (5-ht |
2017-06-28 |
2023-08-13 |
Not clear |
| Nick J Spencer, Damien J Keatin. Is There a Role for Endogenous 5-HT in Gastrointestinal Motility? How Recent Studies Have Changed Our Understanding. Advances in experimental medicine and biology. vol 891. 2017-06-20. PMID:27379639. |
then, perhaps one of the most startling of all observations was the discovery that selective 5-ht receptor antagonists actually have the same inhibitory effects on peristalsis and the migrating complex in segments of intestine that had been depleted of all endogenous 5-ht. |
2017-06-20 |
2023-08-13 |
Not clear |
| Fayrouz El Maddah, Stefan Kehraus, Mamona Nazir, Celso Almeida, Gabriele M Köni. Insights into the Biosynthetic Origin of 3-(3-Furyl)alanine in Stachylidium sp. 293 K04 Tetrapeptides. Journal of natural products. vol 79. issue 11. 2017-06-09. PMID:27786475. |
293 k04 produces the n-methylated peptides endolide a (1) and endolide b (2), showing affinity for the vasopressin receptor 1a and serotonin receptor 5ht |
2017-06-09 |
2023-08-13 |
Not clear |
| Daniel Wacker, Sheng Wang, John D McCorvy, Robin M Betz, A J Venkatakrishnan, Anat Levit, Katherine Lansu, Zachary L Schools, Tao Che, David E Nichols, Brian K Shoichet, Ron O Dror, Bryan L Rot. Crystal Structure of an LSD-Bound Human Serotonin Receptor. Cell. vol 168. issue 3. 2017-05-29. PMID:28129538. |
the prototypical hallucinogen lsd acts via serotonin receptors, and here we describe the crystal structure of lsd in complex with the human serotonin receptor 5-ht |
2017-05-29 |
2023-08-13 |
human |
| M Wierucka-Rybak, M Wolak, M Juszczak, J Drobnik, E Bojanowsk. The inhibitory effect of combination treatment with leptin and cannabinoid CB1 receptor agonist on food intake and body weight gain is mediated by serotonin 1B and 2C receptors. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 67. issue 3. 2017-05-09. PMID:27512006. |
to investigate whether serotonin interacts with leptin and endocannabinoids to affect food intake and body weight, we administered 5-hydroxytryptamine(ht)1b and 5-hydroxytryptamine(ht)2c serotonin receptor antagonists (3 mg/kg gr 127935 and 0.5 mg/kg sb 242084, respectively) to male wistar rats treated simultaneously with leptin (100 μg/kg) and the cb1 receptor inverse agonist am 251 (1 mg/kg) for 3 days. |
2017-05-09 |
2023-08-13 |
rat |
| Takeshi Tsuruta, Shinichi Saito, Yosuke Osaki, Akihiro Hamada, Ayako Aoki-Yoshida, Kei Sonoyam. Organoids as an ex vivo model for studying the serotonin system in the murine small intestine and colon epithelium. Biochemical and biophysical research communications. vol 474. issue 1. 2017-05-08. PMID:27105910. |
reverse transcription-polymerase chain reaction (rt-pcr) analysis showed that small intestinal and colonic organoids express mrnas encoding tryptophan hydroxylase-1 (tph1) (the rate-limiting enzyme of 5-ht synthesis), serotonin reuptake transporter (sert), 5-ht receptor (htr)2a, htr2b, and htr4. |
2017-05-08 |
2023-08-13 |
Not clear |
| Imane Moutkine, Emily Quentin, Bruno P Guiard, Luc Maroteaux, Stephane Dol. Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT The Journal of biological chemistry. vol 292. issue 15. 2017-04-28. PMID:28258217. |
heterodimers of serotonin receptor subtypes 2 are driven by 5-ht the serotonin receptor subtypes 2 comprise 5-ht |
2017-04-28 |
2023-08-13 |
Not clear |
| Nilgun Gurbuz, Mehmet Resit Asoglu, Ahmed A Ashour, Salama Salama, Gokhan S Kilic, Bulent Ozpola. A selective serotonin 5-HT European journal of obstetrics, gynecology, and reproductive biology. vol 206. 2017-04-20. PMID:27669395. |
in this study, we investigated the impact of serotonin receptor 5-ht |
2017-04-20 |
2023-08-13 |
Not clear |