| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Laporta, L L Hernande. Serotonin receptor expression is dynamic in the liver during the transition period in Holstein dairy cows. Domestic animal endocrinology. vol 51. 2015-11-24. PMID:25528206. |
here, we explore circulating patterns of 5-ht and characterize the hepatic 5-ht receptor and glucose transporter profiles around calving in multiparous holstein dairy cows (n = 6, average lactation = 4 ± 1.9). |
2015-11-24 |
2023-08-13 |
cattle |
| M Gertrude Gutierrez, Noah Malmstad. Human serotonin receptor 5-HT(1A) preferentially segregates to the liquid disordered phase in synthetic lipid bilayers. Journal of the American Chemical Society. vol 136. issue 39. 2015-10-28. PMID:25211019. |
human serotonin receptor 5-ht(1a) preferentially segregates to the liquid disordered phase in synthetic lipid bilayers. |
2015-10-28 |
2023-08-13 |
human |
| Michael Aschermann, Pavel Jans. [Drug therapy of pulmonary arterial hypertension in 2014]. Vnitrni lekarstvi. vol 60. issue 4. 2015-10-26. PMID:24985985. |
anti-inflammatory agents: inhibitor of elastase, antagonist of b cells, immunosuppressive agents, inhibitor of hdac1; 3. agents affecting metabolism: nitrites, ppar antagonists, antioxidants, serotonin receptor antagonist and serotonin transporter blockers, statins, inhibitors of rho-kinase; 4. apoptosis inductors of smooth muscle cells: tyrosine-kinase inhibitors, elastase inhibitors; 5. agents influencing vascular regeneration: apelin, treatment targeted to endothelial cells, replacement of bmpr2. |
2015-10-26 |
2023-08-13 |
Not clear |
| Y Yu, D-Q Cao, H-Y Xu, M Sun, Z-L Huang, W-H Yung, N Lu, Y Huan. 5-HT3A receptors are required in long-term depression and AMPA receptor internalization. Neuroscience. vol 278. 2015-10-20. PMID:25130560. |
5-hydroxytrytamine (serotonin) type 3a receptors (5-ht3ars), as the only ligand-gated ion channels in the serotonin receptor family, are known to regulate neuronal excitation and release of gaba in hippocampal interneurons. |
2015-10-20 |
2023-08-13 |
mouse |
| Vaibhav P Pai, Laura L Hernandez, Malinda A Stull, Nelson D Horsema. The type 7 serotonin receptor, 5-HT 7 , is essential in the mammary gland for regulation of mammary epithelial structure and function. BioMed research international. vol 2015. 2015-10-12. PMID:25664318. |
the type 7 serotonin receptor, 5-ht 7 , is essential in the mammary gland for regulation of mammary epithelial structure and function. |
2015-10-12 |
2023-08-13 |
mouse |
| Natascha Nebel, Simone Maschauer, Amelie L Bartuschat, Stefanie K Fehler, Harald Hübner, Peter Gmeiner, Torsten Kuwert, Markus R Heinrich, Olaf Prante, Carsten Hock. Synthesis and evaluation of fluoro substituted pyridinylcarboxamides and their phenylazo analogues for potential dopamine D3 receptor PET imaging. Bioorganic & medicinal chemistry letters. vol 24. issue 23. 2015-10-06. PMID:25453796. |
they also exhibit considerable selectivity over the other dopamine receptor subtypes and noteworthy selectivity over the structurally related serotonin receptor subtypes 5-ht(1a) and 5-ht₂, offering potential radiotracers for positron emission tomography. |
2015-10-06 |
2023-08-13 |
Not clear |
| Sahar Mohammadi, Habibolah Khazaie, Ziba Rahimi, Asad Vaisi-Raygani, Newsha Zargooshi, Zohreh Rahim. The serotonin transporter (5-HTTLPR) but not serotonin receptor (5-HT2C Cys23Ser) variant is associated with bipolar I disorder in Kurdish population from Western Iran. Neuroscience letters. vol 590. 2015-09-14. PMID:25596490. |
the serotonin transporter (5-httlpr) but not serotonin receptor (5-ht2c cys23ser) variant is associated with bipolar i disorder in kurdish population from western iran. |
2015-09-14 |
2023-08-13 |
Not clear |
| Francisco García-Oscos, Oswaldo Torres-Ramírez, Lu Dinh, Luis Galindo-Charles, Elsy Arlene Pérez Padilla, Juan Carlos Pineda, Marco Atzori, Humberto Salgad. Activation of 5-HT receptors inhibits GABAergic transmission by pre-and post-synaptic mechanisms in layer II/III of the juvenile rat auditory cortex. Synapse (New York, N.Y.). vol 69. issue 3. 2015-09-10. PMID:25482075. |
to determine which the serotonin receptors were involved in this effect, we studied the influence of specific 5-ht receptor agonists and antagonists on ɣ-aminobutyric acid (gaba)ergic synaptic transmission. |
2015-09-10 |
2023-08-13 |
rat |
| Elizabeth P Baue. Serotonin in fear conditioning processes. Behavioural brain research. vol 277. 2015-09-08. PMID:25078294. |
the serotonergic system can be manipulated by administering serotonin receptor agonists and antagonists, as well as selective serotonin reuptake inhibitors (ssris), and these can have significant effects on emotional learning and memory. |
2015-09-08 |
2023-08-13 |
Not clear |
| Ashish Dhir, Jayrajsinh Sarvaiy. The efficacy of vortioxetine for the treatment of major depressive disorder. Expert review of neurotherapeutics. vol 14. issue 12. 2015-09-01. PMID:25418918. |
these mechanisms include property to inhibit serotonin reuptake via inhibiting serotonin transporters and acting on multiple serotonin receptor subtypes. |
2015-09-01 |
2023-08-13 |
Not clear |
| Rhonda P Patrick, Bruce N Ame. Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 29. issue 6. 2015-08-24. PMID:25713056. |
we propose mechanisms by which epa increases serotonin release from presynaptic neurons by reducing e2 series prostaglandins and dha influences serotonin receptor action by increasing cell membrane fluidity in postsynaptic neurons. |
2015-08-24 |
2023-08-13 |
Not clear |
| Mousumi Ghosh, Damien D Pears. The role of the serotonergic system in locomotor recovery after spinal cord injury. Frontiers in neural circuits. vol 8. 2015-07-30. PMID:25709569. |
these strategies have included pharmacological modulation of serotonergic receptors, through the administration of specific 5-ht receptor agonists, or by elevating the 5-ht precursor 5-hydroxytryptophan, which produces a global activation of all classes of 5-ht receptors. |
2015-07-30 |
2023-08-13 |
Not clear |
| David Matuskey, Zubin Bhagwagar, Beata Planeta, Brian Pittman, Jean-Dominique Gallezot, Jason Chen, Jane Wanyiri, Soheila Najafzadeh, Jim Ropchan, Paul Geha, Yiyun Huang, Marc N Potenza, Alexander Neumeister, Richard E Carson, Robert T Maliso. Reductions in brain 5-HT1B receptor availability in primarily cocaine-dependent humans. Biological psychiatry. vol 76. issue 10. 2015-07-27. PMID:24433854. |
preclinical evidence implicates the serotonin receptor 5-hydroxytryptamine 1b (5-ht1b) in the effects of cocaine. |
2015-07-27 |
2023-08-12 |
human |
| Mônica Lopes-Ferreira, Eduardo Martins Gomes, Fernanda Miriani Bruni, Marcio Jose Ferreira, Patrícia Charvet, Carla Lim. First report of interruption of mast cell degranulation and endothelial cells activation by anti-inflammatory drugs controlling the acute response provoked by Pseudoplatystoma fasciatum fish venom. Toxicon : official journal of the International Society on Toxinology. vol 90. 2015-06-25. PMID:25152168. |
we found that serotonin, leukotrine and prostaglandin are involved in edematogenic and nociceptive responses, since a selective cox-2 inhibitor, a non-specific inhibitor for cytokines and cox-2, and a non-selective 5-ht receptor antagonist were able to reduce both symptoms. |
2015-06-25 |
2023-08-13 |
mouse |
| Hong-Yan Qin, Chung-Wah Cheng, Xu-Dong Tang, Zhao-Xiang Bia. Impact of psychological stress on irritable bowel syndrome. World journal of gastroenterology. vol 20. issue 39. 2015-06-24. PMID:25339801. |
now, non-pharmacological approaches and pharmacological strategies that target on stress-related alterations, such as antidepressants, antipsychotics, miscellaneous agents, 5-ht synthesis inhibitors, selective 5-ht reuptake inhibitors, and specific 5-ht receptor antagonists or agonists have shown a critical role in ibs management. |
2015-06-24 |
2023-08-13 |
Not clear |
| B N Manukhin, L A Nesterov. [Allosteric effect of serotonin and mianserin on the kinetics of specific [3H]-ligand binding to adrenergic and muscarinic receptors in the rat cerebral cortex membranes]. Izvestiia Akademii nauk. Seriia biologicheskaia. issue 2. 2015-06-24. PMID:26021159. |
the effects of serotonin receptor activation (by serotonin) and inhibition (by mianserin) on the properties of the α1-, α2-adrenoreceptors, and muscarinic cholinergic receptors in subcellular membrane fractions from the rat cerebral cortex were studied. |
2015-06-24 |
2023-08-13 |
rat |
| Christopher S Reigstad, Charles E Salmonson, John F Rainey, Joseph H Szurszewski, David R Linden, Justin L Sonnenburg, Gianrico Farrugia, Purna C Kashya. Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 29. issue 4. 2015-06-22. PMID:25550456. |
microbiota from hm and conventionally raised (cr) mice significantly increased colonic mrnas tph1 [(tryptophan hydroxylase) 1, rate limiting for mucosal 5-ht synthesis; p < 0.01] and chromogranin a (neuroendocrine secretion; p < 0.01), with no effect on monoamine oxidase a (serotonin catabolism), serotonin receptor 5-ht4, or mouse serotonin transporter. |
2015-06-22 |
2023-08-13 |
mouse |
| Leonard L Howell, Kathryn A Cunningha. Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder. Pharmacological reviews. vol 67. issue 1. 2015-06-15. PMID:25505168. |
5-ht receptors are widely expressed throughout the brain, and several different 5-ht receptor subtypes have been implicated in mediating the effects of endogenous 5-ht on da. |
2015-06-15 |
2023-08-13 |
Not clear |
| Zheng-Quan Tang, Laurence O Trussel. Serotonergic regulation of excitability of principal cells of the dorsal cochlear nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 11. 2015-06-15. PMID:25788672. |
using a combination of in vitro electrophysiology and optogenetics in mouse brain slices, we found that 5-ht directly enhances the excitability of fusiform principal cells via activation of two distinct 5-ht receptor subfamilies, 5-ht2a/2cr (5-ht2a/2c receptor) and 5-ht7r (5-ht7 receptor). |
2015-06-15 |
2023-08-13 |
mouse |
| Robin L Davisson, James N Bates, Alan Kim Johnson, Stephen J Lewi. Effects of intracerebroventricular injections of 5-HT on systemic vascular resistances of conscious rats. Microvascular research. vol 95. 2015-06-11. PMID:25128748. |
injections of 5-hydroxytryptamine (5-ht, 10μg) on mean arterial blood pressure (map), heart rate (hr) and mesenteric (mr), renal (rr) and hindquarter (hqr) vascular resistances of conscious rats, (ii) the central 5-ht receptor subtype which mediates these effects, and (iii) the role of nitric oxide (no) in the expression of these responses. |
2015-06-11 |
2023-08-13 |
rat |