| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shaoyuan Li, Chunli Sun, Peijing Rong, Xu Zhai, Jinling Zhang, Max Baker, Shuxing Wan. Auricular vagus nerve stimulation enhances central serotonergic function and inhibits diabetic neuropathy development in Zucker fatty rats. Molecular pain. vol 14. 2018-12-11. PMID:29921169. |
we also demonstrated that this beneficial effect in nociceptive behavior is related to an elevated serotonin (5-ht) plasma concentration and an upregulated expression of 5-ht receptor type 1a (5-ht1ar) in hypothalamus. |
2018-12-11 |
2023-08-13 |
rat |
| Dhana Wolf, Martin Klasen, Patrick Eisner, Florian D Zepf, Mikhail Zvyagintsev, Nicola Palomero-Gallagher, René Weber, Albrecht Eisert, Klaus Mathia. Central serotonin modulates neural responses to virtual violent actions in emotion regulation networks. Brain structure & function. vol 223. issue 7. 2018-12-11. PMID:29948188. |
available 5-ht receptor density data suggest that this ssri effect is only observable when inhibitory and excitatory 5-ht receptors are balanced. |
2018-12-11 |
2023-08-13 |
human |
| Justyna Kalinowska-Tłuścik, Agata Piaskowska, Marcin Kołaczkowsk. Multifunctional arylsulfonamide derivatives with 5-HT Acta crystallographica. Section C, Structural chemistry. vol 74. issue Pt 11. 2018-11-21. PMID:30398204. |
multifunctional arylsulfonamide derivatives with 5-ht nowadays, a search for antagonists co-acting on serotonin receptor subtypes 6 and 7 (5-ht |
2018-11-21 |
2023-08-13 |
Not clear |
| B J Dougherty, J Terada, S R Springborn, S Vinit, P M MacFarlane, G S Mitchel. Daily acute intermittent hypoxia improves breathing function with acute and chronic spinal injury via distinct mechanisms. Respiratory physiology & neurobiology. vol 256. 2018-11-01. PMID:28549897. |
rats were pre-treated with intra-peritoneal vehicle or methysergide, a broad-spectrum serotonin receptor antagonist, to determine the role of serotonin signaling in daih-induced functional recovery. |
2018-11-01 |
2023-08-13 |
rat |
| Lauritz R Meyer, Benjamin Dexter, Cecilia Lo, Elizabeth Kenkel, Takahito Hirai, Robert D Roghair, Sarah E Haskel. Perinatal SSRI exposure permanently alters cerebral serotonin receptor mRNA in mice but does not impact adult behaviors. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. vol 31. issue 11. 2018-09-14. PMID:28385052. |
given the important role serotonin plays in behavior, we hypothesized ssri exposure in the perinatal period would alter central serotonin receptor expression and program adult behaviors in mice. |
2018-09-14 |
2023-08-13 |
mouse |
| Alex Morris, Michael Green, Hayley Martin, Katie Crossland, William T Swaney, Sally M Williamson, Robbie Ra. A nematode that can manipulate the behaviour of slugs. Behavioural processes. vol 151. 2018-09-10. PMID:29499346. |
to investigate how p. hermaphrodita changes slug behaviour we exposed slugs to fluoxetine (a selective serotonin reuptake inhibitor) and cyproheptadine (a serotonin receptor antagonist). |
2018-09-10 |
2023-08-13 |
Not clear |
| Dana Bartlet. Drug-Induced Serotonin Syndrome. Critical care nurse. vol 37. issue 1. 2018-08-06. PMID:28148614. |
serotonin syndrome is a potentially fatal condition caused by drugs that affect serotonin metabolism or act as serotonin receptor agonists. |
2018-08-06 |
2023-08-13 |
Not clear |
| Anastasia Diamantopoulou, Theodora Kalpachidou, Georgios Aspiotis, Ioannis Gampierakis, Fotini Stylianopoulou, Antonios Stamataki. An early experience of mild adversity involving temporary denial of maternal contact affects the serotonergic system of adult male rats and leads to a depressive-like phenotype and inability to adapt to a chronic social stress. Physiology & behavior. vol 184. 2018-08-01. PMID:29127070. |
the depressive-like and anxious phenotype of the der males was accompanied by changes in the serotonergic system, such as lower serotonin levels, higher serotonin turnover and higher levels of the type 1 serotonin receptor in the hippocampus. |
2018-08-01 |
2023-08-13 |
rat |
| Iris Lim, Russ Chess-Williams, Donna Seller. 5-HT2A receptor is the predominant receptor mediating contraction of the isolated porcine distal ureter to 5-HT in young and old animals. European journal of pharmacology. vol 818. 2018-07-27. PMID:29104045. |
responses to 5-ht were examined in the absence and presence of selective 5-ht receptor subtype antagonists. |
2018-07-27 |
2023-08-13 |
Not clear |
| Xinxiu Ren, Lei Liu, Yaser Gamallat, Bingqiang Zhang, Yi Xi. Enteromorpha and polysaccharides from enteromorpha ameliorate loperamide-induced constipation in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 96. 2018-07-27. PMID:29198923. |
in addition, serum nitric oxide (no) content and vasoactive intestinal peptide receptor1 (vipr1) as well as serotonin receptor (5-ht |
2018-07-27 |
2023-08-13 |
mouse |
| Katarzyna Kaczanowska, Gisela Andrea Camacho Hernandez, Larissa Bendiks, Larissa Kohs, Jose Manuel Cornejo-Bravo, Michal Harel, M G Finn, Palmer Taylo. Substituted 2-Aminopyrimidines Selective for α7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins. Journal of the American Chemical Society. vol 139. issue 10. 2018-06-04. PMID:28221788. |
to examine receptor interactions of this structural family on ligand-gated ion channels, we employed hek cells transfected with cdnas encoding three requisite receptor subtypes: α7-nachr, α4β2-nachr, and a serotonin receptor (5-ht |
2018-06-04 |
2023-08-13 |
Not clear |
| Felicia Russ. [Full functional recovery in depression treatment. Clinical cases treated with vortioxetina]. Rivista di psichiatria. vol 52. issue 3. 2018-05-30. PMID:28692076. |
a novel antidepressant, with a multimodal mechanism of action that combines the classical inhibition of serotonin transporter (sert) with the modulation of serotonin receptor activity, is vortioxetine. |
2018-05-30 |
2023-08-13 |
Not clear |
| D Sarrouilhe, C Dejea. [Autism spectrum disorders and bisphenol A: Is serotonin the lacking link in the chain?] L'Encephale. vol 43. issue 4. 2018-05-23. PMID:27623126. |
finally, decreased serotonin transporter and serotonin receptor binding have been reported in both children and adults with autism. |
2018-05-23 |
2023-08-13 |
mouse |
| Bin Tian, Xue-Long Wang, Ya Huang, Li-Hua Chen, Ruo-Xiao Cheng, Feng-Ming Zhou, Ran Guo, Jun-Cheng Li, Tong Li. Peripheral and spinal 5-HT receptors participate in cholestatic itch and antinociception induced by bile duct ligation in rats. Scientific reports. vol 6. 2018-05-08. PMID:27824106. |
although 5-ht has been implicated in cholestatic itch and antinociception, two common phenomena in patients with cholestatic disease, the roles of 5-ht receptor subtypes are unclear. |
2018-05-08 |
2023-08-13 |
rat |
| Yan-Hai Li, Lei Han, Kenneth Lap Kei Wu, Ying-Shing Cha. Activation of 5-HT Neuropharmacology. vol 123. 2018-04-17. PMID:28483393. |
we therefore aim to determine the action of 5-ht on the ltd of type b mvn neurons and elucidate the relevant 5-ht receptor subtypes responsible for its action. |
2018-04-17 |
2023-08-13 |
Not clear |
| Guoxun Zheng, Weiwei Xue, Fengyuan Yang, Yang Zhang, Yuzong Chen, Xiaojun Yao, Feng Zh. Revealing vilazodone's binding mechanism underlying its partial agonism to the 5-HT Physical chemistry chemical physics : PCCP. vol 19. issue 42. 2018-02-09. PMID:29057413. |
various types of drugs, including selective serotonin reuptake inhibitors (ssris), serotonin-norepinephrine reuptake inhibitors (snris), and serotonin receptor partial agonist/reuptake inhibitors (sparis), have been approved and become the primary or first-line medications prescribed for mdd. |
2018-02-09 |
2023-08-13 |
Not clear |
| Daniel Hoye. 5-HT Receptor Nomenclature: Naming Names, Does It Matter? A Tribute to Maurice Rapport. ACS chemical neuroscience. vol 8. issue 5. 2018-02-07. PMID:28269984. |
this is a short personal history on how advances in biochemistry, molecular biology, biophysics, imaging and medicinal chemistry, some lateral thinking, and a decent amount of collaborative spirit within the 5-ht receptor nomenclature committee and the 5-ht community at large have helped to better define the pharmacology of the 5-ht receptor family. |
2018-02-07 |
2023-08-13 |
human |
| T Shiina, K Naitou, H Nakamori, Y Suzuki, K Horii, Y Sano, H Shimaoka, Y Shimiz. Serotonin-induced contractile responses of esophageal smooth muscle in the house musk shrew (Suncus murinus). Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 28. issue 11. 2018-02-05. PMID:27194102. |
therefore, the aims of this study were to determine characteristics of contractile responses induced by serotonin and to identify 5-ht receptor subtypes responsible for regulating motility in the suncus esophagus. |
2018-02-05 |
2023-08-13 |
Not clear |
| K Bannister, S Lockwood, L Goncalves, R Patel, A H Dickenso. An investigation into the inhibitory function of serotonin in diffuse noxious inhibitory controls in the neuropathic rat. European journal of pain (London, England). vol 21. issue 4. 2018-01-31. PMID:27891703. |
here, we manipulate spinal 5-ht content in spinal nerve ligated (snl) animals and investigate which 5-ht receptor mediated actions predominate. |
2018-01-31 |
2023-08-13 |
rat |
| Katherine M Serafine, Kenner C Rice, Charles P Franc. Characterization of the discriminative stimulus effects of lorcaserin in rats. Journal of the experimental analysis of behavior. vol 106. issue 2. 2018-01-29. PMID:27640338. |
lorcaserin is approved by the food and drug administration for treating obesity and is under consideration for treating substance use disorders; it has agonist properties at serotonin (5-ht)2c receptors and might also have agonist properties at other 5-ht receptor subtypes. |
2018-01-29 |
2023-08-13 |
rat |