| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ilona Har-Paz, Nicole Roisman, Daniel M Michaelson, Anan Mora. Extra-Hippocampal Learning Deficits in Young Apolipoprotein E4 Mice and Their Synaptic Underpinning. Journal of Alzheimer's disease : JAD. vol 72. issue 1. 2020-11-05. PMID:31561365. |
while current research regards the hippocampus as the initial and primary effected locus by apoe4, we presently investigate the possibility that apoe4 innately impairs any brain area that requires synaptic plasticity. |
2020-11-05 |
2023-08-13 |
mouse |
| Irene Sánchez-Rodríguez, Souhail Djebari, Sara Temprano-Carazo, David Vega-Avelaira, Raquel Jiménez-Herrera, Guillermo Iborra-Lázaro, Javier Yajeya, Lydia Jiménez-Díaz, Juan D Navarro-Lópe. Hippocampal long-term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing G-protein-gated inwardly rectifying potassium channel activity. Journal of neurochemistry. vol 153. issue 3. 2020-11-04. PMID:31875959. |
hippocampal synaptic plasticity disruption by amyloid-β (aβ) peptides + thought to be responsible for learning and memory impairments in alzheimer's disease (ad) early stage. |
2020-11-04 |
2023-08-13 |
mouse |
| Irene Sánchez-Rodríguez, Souhail Djebari, Sara Temprano-Carazo, David Vega-Avelaira, Raquel Jiménez-Herrera, Guillermo Iborra-Lázaro, Javier Yajeya, Lydia Jiménez-Díaz, Juan D Navarro-Lópe. Hippocampal long-term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing G-protein-gated inwardly rectifying potassium channel activity. Journal of neurochemistry. vol 153. issue 3. 2020-11-04. PMID:31875959. |
here, in early in vitro and in vivo amyloidosis mouse models, we study whether girk channels take part of the hippocampal synaptic plasticity impairments generated by aβ |
2020-11-04 |
2023-08-13 |
mouse |
| Stefania Forner, Alessandra C Martini, G Aleph Prieto, Cindy T Dang, Carlos J Rodriguez-Ortiz, Jorge Mauricio Reyes-Ruiz, Laura Trujillo-Estrada, Celia da Cunha, Elizabeth J Andrews, Jimmy Phan, Jordan Vu Ha, Allissa V Z D Chang, Yona Levites, Pedro E Cruz, Rahasson Ager, Rodrigo Medeiros, Masashi Kitazawa, Charles G Glabe, Carl W Cotman, Todd Golde, David Baglietto-Vargas, Frank M LaFerl. Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus. Scientific reports. vol 9. issue 1. 2020-11-03. PMID:31685865. |
intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus. |
2020-11-03 |
2023-08-13 |
Not clear |
| Ming Wang, Jihoon Jo, Juhyun Son. Adiponectin improves long-term potentiation in the 5XFAD mouse brain. Scientific reports. vol 9. issue 1. 2020-11-02. PMID:31222110. |
thus, adiponectin exhibits beneficial effect on hippocampal synaptic plasticity in alzheimer's disease mouse model. |
2020-11-02 |
2023-08-13 |
mouse |
| Guan-Ling Lu, Ming Tatt Lee, Lih-Chu Chio. Orexin-mediated restoration of hippocampal synaptic potentiation in mice with established cocaine-conditioned place preference. Addiction biology. vol 24. issue 6. 2020-10-28. PMID:30276922. |
orexins (also called hypocretins) are implicated in reward and addiction, but little is known about their role(s) in the association between hippocampal synaptic plasticity and drug preference. |
2020-10-28 |
2023-08-13 |
mouse |
| Saatheeyavaane Bhuvanendran, Siti Najmi Syuhadaa Bakar, Yatinesh Kumari, Iekhsan Othman, Mohd Farooq Shaikh, Zurina Hassa. Embelin Improves the Spatial Memory and Hippocampal Long-Term Potentiation in a Rat Model of Chronic Cerebral Hypoperfusion. Scientific reports. vol 9. issue 1. 2020-10-27. PMID:31601902. |
embelin treatment has significantly protected synaptic plasticity impairment as assessed by hippocampal long-term potentiation (ltp) test. |
2020-10-27 |
2023-08-13 |
rat |
| Guillermo González-H, Itzel Jatziri Contreras-García, Karla Sánchez-Huerta, Claudio M T Queiroz, Luis Ricardo Gallardo Gudiño, Julieta G Mendoza-Torreblanca, Sergio R Zamudi. Levetiracetam Reduced the Basal Excitability of the Dentate Gyrus without Restoring Impaired Synaptic Plasticity in Rats with Temporal Lobe Epilepsy. Brain sciences. vol 10. issue 9. 2020-10-27. PMID:32933015. |
therefore, through the measurement of evoked field potentials, this study aimed to comprehensively identify the alterations in the excitability and the short-term (depression/facilitation) and long-term synaptic plasticity (long-term potentiation, ltp) of the dentate gyrus of the hippocampus in a lithium-pilocarpine rat model of tle, as well as their possible restoration by lev (1 week; 300 mg/kg/day). |
2020-10-27 |
2023-08-13 |
rat |
| Antonio de Iure, Petra Mazzocchetti, Guendalina Bastioli, Barbara Picconi, Cinzia Costa, Ivan Marchionni, Giorgio Casari, Alessandro Tozzi, Daniela Pietrobon, Paolo Calabres. Differential effect of FHM2 mutation on synaptic plasticity in distinct hippocampal regions. Cephalalgia : an international journal of headache. vol 39. issue 10. 2020-10-26. PMID:30922082. |
differential effect of fhm2 mutation on synaptic plasticity in distinct hippocampal regions. |
2020-10-26 |
2023-08-13 |
Not clear |
| Tala Khazen, Ossama A Hatoum, Guillaume Ferreira, Mouna Marou. Acute exposure to a high-fat diet in juvenile male rats disrupts hippocampal-dependent memory and plasticity through glucocorticoids. Scientific reports. vol 9. issue 1. 2020-10-20. PMID:31439894. |
juvenile hfd abolished both hippocampal synaptic plasticity, assessed through in vivo long-term potentiation (ltp) in ca1, and long-term hippocampal-dependent memory, using object location memory (olm). |
2020-10-20 |
2023-08-13 |
rat |
| Xialin Sun, Tingwen Zhang, Yan Zhao, Enbo Cai, Hongyan Zhu, Shuangli Li. Panaxynol attenuates CUMS-induced anxiety and depressive-like behaviors via regulating neurotransmitters, synapses and the HPA axis in mice. Food & function. vol 11. issue 2. 2020-10-19. PMID:32048672. |
meanwhile, pal promotes the release of 5-ht and da in the hippocampus and improves synaptic plasticity in the hippocampus, allowing neurotransmitters to function more effectively. |
2020-10-19 |
2023-08-13 |
mouse |
| Yingrak Boondam, Phanit Songvut, Mayuree H Tantisira, Sompol Tapechum, Kanokwan Tilokskulchai, Narawut Pakapro. Inverted U-shaped response of a standardized extract of Centella asiatica (ECa 233) on memory enhancement. Scientific reports. vol 9. issue 1. 2020-10-14. PMID:31182820. |
we used the morris water maze to test spatial learning and performed acute brain slice recording to measure changes of synaptic plasticity in the hippocampus, a core brain region for memory formation. |
2020-10-14 |
2023-08-13 |
rat |
| Yingrak Boondam, Phanit Songvut, Mayuree H Tantisira, Sompol Tapechum, Kanokwan Tilokskulchai, Narawut Pakapro. Inverted U-shaped response of a standardized extract of Centella asiatica (ECa 233) on memory enhancement. Scientific reports. vol 9. issue 1. 2020-10-14. PMID:31182820. |
there was an inverted u-shaped response of eca 233 on memory enhancement; 30 mg/kg maximally enhanced memory retention with an increase of synaptic plasticity and plasticity-related proteins in hippocampus. |
2020-10-14 |
2023-08-13 |
rat |
| Yao Wang, Yu-Zhang Liu, Lidan Wang, Wei Tang, Zhiru Wan. Silent Synapse Unsilencing in Hippocampal CA1 Neurons for Associative Fear Memory Storage. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30462151. |
clarifying learning-induced synaptic plasticity in hippocampal circuits is critical for understanding hippocampal mechanisms of memory acquisition and storage. |
2020-10-13 |
2023-08-13 |
mouse |
| Yao Wang, Yu-Zhang Liu, Lidan Wang, Wei Tang, Zhiru Wan. Silent Synapse Unsilencing in Hippocampal CA1 Neurons for Associative Fear Memory Storage. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30462151. |
however, as a neural basis of memory encoding, the nature of synaptic plasticity underlying hippocampal neuronal responses to memorized stimulation remains elusive. |
2020-10-13 |
2023-08-13 |
mouse |
| Emilce Artur de la Villarmois, Laura A Gabach, Santiago Bianconi, Maria Belen Poretti, Victoria Occhieppo, Helgi B Schiöth, Valeria P Carlini, Mariela Fernanda Pére. Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31378002. |
particularly, cocaine sensitization in rats enhanced synaptic plasticity within the hippocampus, an important brain region for the associative learning processes underlying drug addiction. |
2020-10-07 |
2023-08-13 |
rat |
| Emilce Artur de la Villarmois, Laura A Gabach, Santiago Bianconi, Maria Belen Poretti, Victoria Occhieppo, Helgi B Schiöth, Valeria P Carlini, Mariela Fernanda Pére. Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31378002. |
nitric oxide (no) is a neurotransmitter involved in both, hippocampal synaptic plasticity and cocaine sensitization. |
2020-10-07 |
2023-08-13 |
rat |
| Emilce Artur de la Villarmois, Laura A Gabach, Santiago Bianconi, Maria Belen Poretti, Victoria Occhieppo, Helgi B Schiöth, Valeria P Carlini, Mariela Fernanda Pére. Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31378002. |
it has been previously demonstrated a key role of nos-1/no/sgc/cgmp signaling pathway in the development of cocaine sensitization and in the associated enhancement of hippocampal synaptic plasticity. |
2020-10-07 |
2023-08-13 |
rat |
| Emilce Artur de la Villarmois, Laura A Gabach, Santiago Bianconi, Maria Belen Poretti, Victoria Occhieppo, Helgi B Schiöth, Valeria P Carlini, Mariela Fernanda Pére. Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31378002. |
nos-1 inhibition after sensitization reversed behavioral expression and the highest level of hippocampal synaptic plasticity. |
2020-10-07 |
2023-08-13 |
rat |
| Jessica L Huebschman, Kitzia S Corona, Yuhong Guo, Laura N Smit. The Fragile X Mental Retardation Protein Regulates Striatal Medium Spiny Neuron Synapse Density and Dendritic Spine Morphology. Frontiers in molecular neuroscience. vol 13. 2020-10-06. PMID:33013316. |
loss of fmrp, as in fragile x syndrome (fxs), is a leading monogenic cause of autism and results in altered structural and functional synaptic plasticity, widely described in the hippocampus and cortex. |
2020-10-06 |
2023-08-13 |
Not clear |