| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ivani Credidio Trombetta, José Roberto DeMoura, Cleber Rene Alves, Renato Carbonari-Brito, Felipe Xerez Cepeda, José Ribeiro Lemo. Serum Levels of BDNF in Cardiovascular Protection and in Response to Exercise. Arquivos brasileiros de cardiologia. vol 115. issue 2. 2020-12-04. PMID:32876194. |
bdnf is a neurotrophin found at high concentrations in the hippocampus and cerebral cortex and is considered a key molecule for the maintenance of synaptic plasticity and survival of neuronal cells. |
2020-12-04 |
2023-08-13 |
Not clear |
| E Segabinazi, N F Gasperini, A M Faustino, R Centeno, A S Dos Santos, W de Almeida, L P Bronauth, S Marcuzzo, L O Pereir. Comparative overview of the effects of aerobic and resistance exercise on anxiety-like behavior, cognitive flexibility, and hippocampal synaptic plasticity parameters in healthy rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 11. 2020-12-01. PMID:33053097. |
comparative overview of the effects of aerobic and resistance exercise on anxiety-like behavior, cognitive flexibility, and hippocampal synaptic plasticity parameters in healthy rats. |
2020-12-01 |
2023-08-13 |
rat |
| Javed Iqbal, Zhi-Nei Tan, Min-Xing Li, Hui-Bin Chen, Boyu Ma, Xin Zhou, Xin-Ming M. Estradiol Alters Hippocampal Gene Expression during the Estrous Cycle. Endocrine research. vol 45. issue 2. 2020-11-25. PMID:31608702. |
estrogen (e2) modulates a wide range of neural functions such as spine formation, synaptic plasticity, and neurotransmission in the hippocampus. |
2020-11-25 |
2023-08-13 |
rat |
| Shan Shi, Ke Ma, Na-Ryum Bin, Hidekiyo Harada, Xiaoyu Xie, Mengjia Huang, Haiyu Liu, Soomin Lee, Xue Fan Wang, Roberto Adachi, Philippe P Monnier, Liang Zhang, Shuzo Sugit. Syntaxin-3 is dispensable for basal neurotransmission and synaptic plasticity in postsynaptic hippocampal CA1 neurons. Scientific reports. vol 10. issue 1. 2020-11-25. PMID:31959797. |
together, our data suggest that syntaxin-3 is dispensable for hippocampal basal neurotransmission and synaptic plasticity, and further supports the notion that syntaxin-4 is the major isoform mediating these processes. |
2020-11-25 |
2023-08-13 |
mouse |
| Cleiton Lopes-Aguiar, Rafael N Ruggiero, Matheus T Rossignoli, Ingrid de Miranda Esteves, José Eduardo Peixoto-Santos, Rodrigo N Romcy-Pereira, João P Leit. Long-term potentiation prevents ketamine-induced aberrant neurophysiological dynamics in the hippocampus-prefrontal cortex pathway in vivo. Scientific reports. vol 10. issue 1. 2020-11-25. PMID:32346044. |
nmdar hypofunction affects normal oscillatory dynamics and synaptic plasticity in key brain regions related to schizophrenia, particularly in the hippocampus and the prefrontal cortex. |
2020-11-25 |
2023-08-13 |
rat |
| b' Marta Rolland, Rebecca Powell, Muriel Jacquier-Sarlin, Sylvie Boisseau, Robin Reynaud-Dulaurier, Jose Martinez-Hernandez, Louise Andr\\xc3\\xa9, Eve Borel, Alain Buisson, Fabien Lant\\xc3\\xa. Effect of A\\xce\\xb2 Oligomers on Neuronal APP Triggers a Vicious Cycle Leading to the Propagation of Synaptic Plasticity Alterations to Healthy Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 27. 2020-11-23. PMID:32444385.' |
we used complementary techniques ranging from electrophysiological recordings and molecular biology to confocal microscopy in primary cortical cultures, and from acute hippocampal and cortical slices from male wild-type and amyloid precursor protein (app) knock-out (ko) mice to assess the effects of aβos on glutamatergic transmission, synaptic plasticity, and dendritic spine structure. |
2020-11-23 |
2023-08-13 |
mouse |
| Xiumin Zhang, Fang Zhao, Chenfang Wang, Jun Zhang, Yu Bai, Fang Zhou, Zhaojun Wang, Meina Wu, Wei Yang, Junhong Guo, Jinshun Q. AVP(4-8) Improves Cognitive Behaviors and Hippocampal Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer's Disease. Neuroscience bulletin. vol 36. issue 3. 2020-11-20. PMID:31605298. |
avp(4-8) improves cognitive behaviors and hippocampal synaptic plasticity in the app/ps1 mouse model of alzheimer's disease. |
2020-11-20 |
2023-08-13 |
mouse |
| Xiumin Zhang, Fang Zhao, Chenfang Wang, Jun Zhang, Yu Bai, Fang Zhou, Zhaojun Wang, Meina Wu, Wei Yang, Junhong Guo, Jinshun Q. AVP(4-8) Improves Cognitive Behaviors and Hippocampal Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer's Disease. Neuroscience bulletin. vol 36. issue 3. 2020-11-20. PMID:31605298. |
these results reveal the beneficial effects of avp(4-8) in app/ps1-ad mice, showing that the intranasal administration of avp(4-8) effectively improved the working memory and long-term spatial memory of app/ps1-ad mice, which may be associated with the elevation of psd95 and ngf levels in the brain and the maintenance of hippocampal synaptic plasticity. |
2020-11-20 |
2023-08-13 |
mouse |
| Sheng-Tzung Tsai, Shin-Yuan Chen, Shinn-Zong Lin, Guo-Fang Tsen. Rostral intralaminar thalamic deep brain stimulation ameliorates memory deficits and dendritic regression in β-amyloid-infused rats. Brain structure & function. vol 225. issue 2. 2020-11-20. PMID:32036422. |
spatial memory was tested in the morris water maze (mwm), while structural synaptic plasticity and glutamatergic transmission strength were estimated by measuring dendritic spine densities in dye-injected neurons and tissue expression levels of postsynaptic density protein 95 (psd-95) in medial prefrontal cortex (mpfc) and hippocampus. |
2020-11-20 |
2023-08-13 |
rat |
| Genevieve Saw, Kumar Krishna, Neelima Gupta, Tuck Wah Soong, Karthik Mallilankaraman, Sreedharan Sajikumar, S Thameem Dhee. Epigenetic regulation of microglial phosphatidylinositol 3-kinase pathway involved in long-term potentiation and synaptic plasticity in rats. Glia. vol 68. issue 3. 2020-11-19. PMID:31702864. |
however, ltp was rescued when the same hippocampal slices were treated with active pi3k or bdnf, indicating that microglial pi3k/akt signaling contributes to ltp and synaptic plasticity. |
2020-11-19 |
2023-08-13 |
rat |
| Katisha R Gopaul, Muhammad Irfan, Omid Miry, Linnea R Vose, Alexander Moghadam, Galadu Subah, Tomas Hökfelt, Christina Bark, Patric K Stanto. Developmental Time Course of SNAP-25 Isoforms Regulate Hippocampal Long-Term Synaptic Plasticity and Hippocampus-Dependent Learning. International journal of molecular sciences. vol 21. issue 4. 2020-11-19. PMID:32093363. |
developmental time course of snap-25 isoforms regulate hippocampal long-term synaptic plasticity and hippocampus-dependent learning. |
2020-11-19 |
2023-08-13 |
mouse |
| Wenchong Sun, Jian Wang, Dasheng Cai, Ling Pe. Neuroprotection of the Developing Brain by Dexmedetomidine Is Mediated by Attenuating Single Propofol-induced Hippocampal Apoptosis and Synaptic Plasticity Deficits. Experimental neurobiology. vol 29. issue 5. 2020-11-14. PMID:33154198. |
neuroprotection of the developing brain by dexmedetomidine is mediated by attenuating single propofol-induced hippocampal apoptosis and synaptic plasticity deficits. |
2020-11-14 |
2023-08-13 |
rat |
| Wenchong Sun, Jian Wang, Dasheng Cai, Ling Pe. Neuroprotection of the Developing Brain by Dexmedetomidine Is Mediated by Attenuating Single Propofol-induced Hippocampal Apoptosis and Synaptic Plasticity Deficits. Experimental neurobiology. vol 29. issue 5. 2020-11-14. PMID:33154198. |
after a single propofol exposure to p7 rats, dex pretreatment effectively rescued the profound apoptosis seen in hippocampal neurocytes, and strongly reversed the aberrant expression levels of bcl2-like 1 (bcl2l1), matrix metallopeptidase 9 (mmp-9) and cleaved caspase 3 (cc3), and sharply enhanced synaptic plasticity. |
2020-11-14 |
2023-08-13 |
rat |
| Ilona Har-Paz, Nicole Roisman, Daniel M Michaelson, Anan Mora. Extra-Hippocampal Learning Deficits in Young Apolipoprotein E4 Mice and Their Synaptic Underpinning. Journal of Alzheimer's disease : JAD. vol 72. issue 1. 2020-11-05. PMID:31561365. |
while current research regards the hippocampus as the initial and primary effected locus by apoe4, we presently investigate the possibility that apoe4 innately impairs any brain area that requires synaptic plasticity. |
2020-11-05 |
2023-08-13 |
mouse |
| Irene Sánchez-Rodríguez, Souhail Djebari, Sara Temprano-Carazo, David Vega-Avelaira, Raquel Jiménez-Herrera, Guillermo Iborra-Lázaro, Javier Yajeya, Lydia Jiménez-Díaz, Juan D Navarro-Lópe. Hippocampal long-term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing G-protein-gated inwardly rectifying potassium channel activity. Journal of neurochemistry. vol 153. issue 3. 2020-11-04. PMID:31875959. |
hippocampal synaptic plasticity disruption by amyloid-β (aβ) peptides + thought to be responsible for learning and memory impairments in alzheimer's disease (ad) early stage. |
2020-11-04 |
2023-08-13 |
mouse |
| Irene Sánchez-Rodríguez, Souhail Djebari, Sara Temprano-Carazo, David Vega-Avelaira, Raquel Jiménez-Herrera, Guillermo Iborra-Lázaro, Javier Yajeya, Lydia Jiménez-Díaz, Juan D Navarro-Lópe. Hippocampal long-term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing G-protein-gated inwardly rectifying potassium channel activity. Journal of neurochemistry. vol 153. issue 3. 2020-11-04. PMID:31875959. |
here, in early in vitro and in vivo amyloidosis mouse models, we study whether girk channels take part of the hippocampal synaptic plasticity impairments generated by aβ |
2020-11-04 |
2023-08-13 |
mouse |
| Stefania Forner, Alessandra C Martini, G Aleph Prieto, Cindy T Dang, Carlos J Rodriguez-Ortiz, Jorge Mauricio Reyes-Ruiz, Laura Trujillo-Estrada, Celia da Cunha, Elizabeth J Andrews, Jimmy Phan, Jordan Vu Ha, Allissa V Z D Chang, Yona Levites, Pedro E Cruz, Rahasson Ager, Rodrigo Medeiros, Masashi Kitazawa, Charles G Glabe, Carl W Cotman, Todd Golde, David Baglietto-Vargas, Frank M LaFerl. Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus. Scientific reports. vol 9. issue 1. 2020-11-03. PMID:31685865. |
intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus. |
2020-11-03 |
2023-08-13 |
Not clear |
| Ming Wang, Jihoon Jo, Juhyun Son. Adiponectin improves long-term potentiation in the 5XFAD mouse brain. Scientific reports. vol 9. issue 1. 2020-11-02. PMID:31222110. |
thus, adiponectin exhibits beneficial effect on hippocampal synaptic plasticity in alzheimer's disease mouse model. |
2020-11-02 |
2023-08-13 |
mouse |
| Guan-Ling Lu, Ming Tatt Lee, Lih-Chu Chio. Orexin-mediated restoration of hippocampal synaptic potentiation in mice with established cocaine-conditioned place preference. Addiction biology. vol 24. issue 6. 2020-10-28. PMID:30276922. |
orexins (also called hypocretins) are implicated in reward and addiction, but little is known about their role(s) in the association between hippocampal synaptic plasticity and drug preference. |
2020-10-28 |
2023-08-13 |
mouse |
| Saatheeyavaane Bhuvanendran, Siti Najmi Syuhadaa Bakar, Yatinesh Kumari, Iekhsan Othman, Mohd Farooq Shaikh, Zurina Hassa. Embelin Improves the Spatial Memory and Hippocampal Long-Term Potentiation in a Rat Model of Chronic Cerebral Hypoperfusion. Scientific reports. vol 9. issue 1. 2020-10-27. PMID:31601902. |
embelin treatment has significantly protected synaptic plasticity impairment as assessed by hippocampal long-term potentiation (ltp) test. |
2020-10-27 |
2023-08-13 |
rat |