| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyungdeok Kim, Wangyong Shin, Muwon Kang, Suho Lee, Doyoun Kim, Ryeonghwa Kang, Yewon Jung, Yisul Cho, Esther Yang, Hyun Kim, Yong Chul Bae, Eunjoon Ki. Presynaptic PTPσ regulates postsynaptic NMDA receptor function through direct adhesion-independent mechanisms. eLife. vol 9. 2021-05-04. PMID:32142410. |
here we report that presynaptic ptpσ, a lar-rptp, enhances postsynaptic nmda receptor (nmdar) currents and nmdar-dependent synaptic plasticity in the hippocampus. |
2021-05-04 |
2023-08-13 |
mouse |
| Ye Wang, Wing-Yu Fu, Kit Cheung, Kwok-Wang Hung, Congping Chen, Hongyan Geng, Wing-Ho Yung, Jianan Y Qu, Amy K Y Fu, Nancy Y I. Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 1. 2021-04-30. PMID:33443211. |
astrocyte-secreted il-33 mediates homeostatic synaptic plasticity in the adult hippocampus. |
2021-04-30 |
2023-08-13 |
mouse |
| Ye Wang, Wing-Yu Fu, Kit Cheung, Kwok-Wang Hung, Congping Chen, Hongyan Geng, Wing-Ho Yung, Jianan Y Qu, Amy K Y Fu, Nancy Y I. Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 1. 2021-04-30. PMID:33443211. |
hippocampal synaptic plasticity is important for learning and memory formation. |
2021-04-30 |
2023-08-13 |
mouse |
| Ye Wang, Wing-Yu Fu, Kit Cheung, Kwok-Wang Hung, Congping Chen, Hongyan Geng, Wing-Ho Yung, Jianan Y Qu, Amy K Y Fu, Nancy Y I. Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 1. 2021-04-30. PMID:33443211. |
these results collectively reveal an important role of astrocytic il-33 in mediating the negative-feedback signaling mechanism in homeostatic synaptic plasticity, providing insights into how astrocytes maintain hippocampal network homeostasis. |
2021-04-30 |
2023-08-13 |
mouse |
| Seyed Asaad Karimi, Somayeh Komaki, Masoumeh Taheri, Ghazaleh Omidi, Masoumeh Kourosh-Arami, Iraj Salehi, Alireza Komak. Effects of the hydroalcoholic extract of Rosa damascena on hippocampal long-term potentiation in rats fed high-fat diet. The journal of physiological sciences : JPS. vol 71. issue 1. 2021-04-30. PMID:33926383. |
consumption of hfd is associated with reduction in hippocampal synaptic plasticity. |
2021-04-30 |
2023-08-13 |
rat |
| Seyed Asaad Karimi, Somayeh Komaki, Masoumeh Taheri, Ghazaleh Omidi, Masoumeh Kourosh-Arami, Iraj Salehi, Alireza Komak. Effects of the hydroalcoholic extract of Rosa damascena on hippocampal long-term potentiation in rats fed high-fat diet. The journal of physiological sciences : JPS. vol 71. issue 1. 2021-04-30. PMID:33926383. |
this study was carried out to determine the beneficial effect of hydroalcoholic extract of r. damascena on in vivo hippocampal synaptic plasticity (long-term potentiation, ltp) in the perforant pathway (pp)-dentate gyrus (dg) pathway in rats fed with an hfd. |
2021-04-30 |
2023-08-13 |
rat |
| Jun-Jie Tang, Shuang Feng, Xing-Dong Chen, Hua Huang, Min Mao, Hai-Yan Wang, Sen Li, Xiu-Min Lu, Yong-Tang Wan. The Effects of P75NTR on Learning Memory Mediated by Hippocampal Apoptosis and Synaptic Plasticity. Current pharmaceutical design. vol 27. issue 4. 2021-04-26. PMID:32938344. |
the effects of p75ntr on learning memory mediated by hippocampal apoptosis and synaptic plasticity. |
2021-04-26 |
2023-08-13 |
Not clear |
| Md Sahab Uddin, Sharifa Hasana, Jamil Ahmad, Md Farhad Hossain, Md Mosiqur Rahman, Tapan Behl, Abdur Rauf, Ausaf Ahmad, Abdul Hafeez, Asma Perveen, Ghulam Md Ashra. Anti-Neuroinflammatory Potential of Polyphenols by Inhibiting NF-κB to Halt Alzheimer's Disease. Current pharmaceutical design. vol 27. issue 3. 2021-04-26. PMID:33213314. |
aβ can induce apoptosis, trigger an inflammatory response, and inhibit the synaptic plasticity of the hippocampus, which ultimately contributes to reducing cognitive functions and memory impairment. |
2021-04-26 |
2023-08-13 |
Not clear |
| Anna Pensalfini, Seonil Kim, Shivakumar Subbanna, Cynthia Bleiwas, Chris N Goulbourne, Philip H Stavrides, Ying Jiang, Ju-Hyun Lee, Sandipkumar Darji, Monika Pawlik, Chunfeng Huo, James Peddy, Martin J Berg, John F Smiley, Balapal S Basavarajappa, Ralph A Nixo. Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease. Cell reports. vol 33. issue 8. 2021-04-26. PMID:33238112. |
modest neuron-specific transgenic rab5 expression inducing hyperactivation of rab5 comparable to that in ad brain reproduces ad-related rab5-endosomal enlargement and mistrafficking, hippocampal synaptic plasticity deficits via accelerated ampar endocytosis and dendritic spine loss, and tau hyperphosphorylation via activated glycogen synthase kinase-3β. |
2021-04-26 |
2023-08-13 |
mouse |
| Leila Khatami, Vajihe Safari, Fereshteh Motamed. Temporary inactivation of interpeduncular nucleus impairs long but not short term plasticity in the perforant-path dentate gyrus synapses in rats. Behavioural brain research. vol 377. 2021-04-23. PMID:31505188. |
all together our study suggests the contribution of ipn in the ppdg synaptic plasticity and excitability of dg granule cells which could be through direct and/or indirect pathways from ipn to the hippocampus. |
2021-04-23 |
2023-08-13 |
rat |
| Bingrui Xiong, Wen Zhang, Longqing Zhang, Xian Huang, Wenchang Zhou, Qian Zou, Anne Manyande, Jie Wang, Yuke Tian, Xuebi Tia. Hippocampal glutamatergic synapses impairment mediated novel-object recognition dysfunction in rats with neuropathic pain. Pain. vol 161. issue 8. 2021-04-21. PMID:32701842. |
ultra-high-performance liquid chromatography revealed lower levels of d-serine in the hippocampus of the spared nerve injury rats and that d-serine treatment could restore synaptic plasticity and cognitive dysfunction. |
2021-04-21 |
2023-08-13 |
rat |
| Qian Yang, Yusen Zhang, Luping Zhang, Xuemin Li, Ruirui Dong, Chenmeng Song, Le Cheng, Mengqian Shi, Haifeng Zha. Combination of tea polyphenols and proanthocyanidins prevents menopause-related memory decline in rats via increased hippocampal synaptic plasticity by inhibiting p38 MAPK and TNF-α pathway. Nutritional neuroscience. 2021-04-19. PMID:33871312. |
combination of tea polyphenols and proanthocyanidins prevents menopause-related memory decline in rats via increased hippocampal synaptic plasticity by inhibiting p38 mapk and tnf-α pathway. |
2021-04-19 |
2023-08-13 |
rat |
| Alexander Popov, Pavel Denisov, Maxim Bychkov, Alexey Brazhe, Ekaterina Lyukmanova, Zakhar Shenkarev, Natalia Lazareva, Alexei Verkhratsky, Alexey Semyano. Caloric restriction triggers morphofunctional remodeling of astrocytes and enhances synaptic plasticity in the mouse hippocampus. Cell death & disease. vol 11. issue 3. 2021-04-13. PMID:32231202. |
caloric restriction triggers morphofunctional remodeling of astrocytes and enhances synaptic plasticity in the mouse hippocampus. |
2021-04-13 |
2023-08-13 |
mouse |
| Soomaayeh Heysieattalab, Ka-Hung Lee, Yan Liu, Yubin Wang, Michael R Foy, Xiaoning Bi, Michel Baudr. Impaired cerebellar plasticity and eye-blink conditioning in calpain-1 knock-out mice. Neurobiology of learning and memory. vol 170. 2021-04-12. PMID:30735788. |
our recent studies indicate that calpain-1 is required for hippocampal synaptic plasticity, including long-term depression (ltd) and long-term potentiation (ltp) in field ca1. |
2021-04-12 |
2023-08-13 |
mouse |
| Soomaayeh Heysieattalab, Ka-Hung Lee, Yan Liu, Yubin Wang, Michael R Foy, Xiaoning Bi, Michel Baudr. Impaired cerebellar plasticity and eye-blink conditioning in calpain-1 knock-out mice. Neurobiology of learning and memory. vol 170. 2021-04-12. PMID:30735788. |
our results indicate that calpain-1 plays critical roles in multiple forms of synaptic plasticity and associative learning in both hippocampus and cerebellum. |
2021-04-12 |
2023-08-13 |
mouse |
| Fahime Zavvari, Arezo Nahavandi, Ali Shahbaz. Neuroprotective effects of cerium oxide nanoparticles on experimental stress-induced depression in male rats. Journal of chemical neuroanatomy. vol 106. 2021-04-06. PMID:32371049. |
inflammation and oxidative/nitrative stress induced by chronic psychosocial or physical stress play fundamental roles in the pathogenesis of depression, and lead to the loss of neurotrophic support, decreased neurogenesis and synaptic plasticity in the hippocampus. |
2021-04-06 |
2023-08-13 |
rat |
| Hong-Qing Zhao, Jian Liu, Pan Meng, Hui Yang, Xiao-Yuan Lin, Hong-Ping Long, Xi-Ming Yu, Yu-Hong Wan. [Effect of Baihe Dihuang Decoction on synaptic plasticity of hippocampus in rats with anxious depression]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 5. 2021-04-02. PMID:33787116. |
[effect of baihe dihuang decoction on synaptic plasticity of hippocampus in rats with anxious depression]. |
2021-04-02 |
2023-08-13 |
rat |
| Hong-Qing Zhao, Jian Liu, Pan Meng, Hui Yang, Xiao-Yuan Lin, Hong-Ping Long, Xi-Ming Yu, Yu-Hong Wan. [Effect of Baihe Dihuang Decoction on synaptic plasticity of hippocampus in rats with anxious depression]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 5. 2021-04-02. PMID:33787116. |
to explore the effect of baihe dihuang decoction on the synaptic plasticity of hippocampal neurons in rats with anxious depression. |
2021-04-02 |
2023-08-13 |
rat |
| Hong-Qing Zhao, Jian Liu, Pan Meng, Hui Yang, Xiao-Yuan Lin, Hong-Ping Long, Xi-Ming Yu, Yu-Hong Wan. [Effect of Baihe Dihuang Decoction on synaptic plasticity of hippocampus in rats with anxious depression]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 5. 2021-04-02. PMID:33787116. |
immunofluorescence was used to detect the expression of hippocampal synaptic plasticity protein synapsin-1 and postsynaptic density protein 95(psd-95). |
2021-04-02 |
2023-08-13 |
rat |
| Hong-Qing Zhao, Jian Liu, Pan Meng, Hui Yang, Xiao-Yuan Lin, Hong-Ping Long, Xi-Ming Yu, Yu-Hong Wan. [Effect of Baihe Dihuang Decoction on synaptic plasticity of hippocampus in rats with anxious depression]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 5. 2021-04-02. PMID:33787116. |
therefore, we believe that baihe dihuang decoction can improve anxiety and depression behaviors by regulating the synaptic plasticity of hippocampal neurons. |
2021-04-02 |
2023-08-13 |
rat |