Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Julia C Bartsch, Monique von Cramon, David Gruber, Uwe Heinemann, Joachim Beh. Stress-Induced Enhanced Long-Term Potentiation and Reduced Threshold for N-Methyl-D-Aspartate Receptor- and β-Adrenergic Receptor-Mediated Synaptic Plasticity in Rodent Ventral Subiculum. Frontiers in molecular neuroscience. vol 14. 2021-05-13. PMID:33967694. |
stress is a biologically relevant signal and can modulate hippocampal synaptic plasticity. |
2021-05-13 |
2023-08-13 |
rat |
Yanyan Feng, Chaojun Duan, Zhaohui Luo, Wenbiao Xiao, Fafa Tia. Silencing miR-20a-5p inhibits axonal growth and neuronal branching and prevents epileptogenesis through RGMa-RhoA-mediated synaptic plasticity. Journal of cellular and molecular medicine. vol 24. issue 18. 2021-05-12. PMID:32779334. |
furthermore, in primary hippocampal neurons, the mir-20a-5p-rgma-rhoa pathway regulated axonal growth and neuronal branching; in the ptz-induced epilepsy model, silencing mir-20a-5p prevented epileptogenesis through rgma-rhoa-mediated synaptic plasticity but did not change mfs. |
2021-05-12 |
2023-08-13 |
Not clear |
Fatima Javed Mirza, Sanila Amber, Sumera, Deeba Hassan, Touqeer Ahmed, Saadia Zahi. Rosmarinic acid and ursolic acid alleviate deficits in cognition, synaptic regulation and adult hippocampal neurogenesis in an Aβ Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 83. 2021-05-11. PMID:33601255. |
recent findings correlate impaired adult neurogenesis, which is crucial for the maintenance of synaptic plasticity and hippocampal functioning, synaptic regulation with the pathological hallmarks of alzheimer's disease (ad). |
2021-05-11 |
2023-08-13 |
Not clear |
Ye Wang, Amy K Y Fu, Nancy Y I. Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms. The FEBS journal. 2021-05-11. PMID:33864430. |
instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms. |
2021-05-11 |
2023-08-13 |
mouse |
Ye Wang, Amy K Y Fu, Nancy Y I. Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms. The FEBS journal. 2021-05-11. PMID:33864430. |
in the adult hippocampus, synaptic plasticity is important for information processing, learning, and memory encoding. |
2021-05-11 |
2023-08-13 |
mouse |
Ye Wang, Amy K Y Fu, Nancy Y I. Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms. The FEBS journal. 2021-05-11. PMID:33864430. |
astrocytes, the most common glial cells, play a pivotal role in the regulation of hippocampal synaptic plasticity. |
2021-05-11 |
2023-08-13 |
mouse |
Ye Wang, Amy K Y Fu, Nancy Y I. Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms. The FEBS journal. 2021-05-11. PMID:33864430. |
while astrocytes were initially described as a homogenous cell population, emerging evidence indicates that in the adult hippocampus, astrocytes are highly heterogeneous and can differentially respond to changes in neuronal activity in a subregion-dependent manner to actively modulate synaptic plasticity. |
2021-05-11 |
2023-08-13 |
mouse |
Ye Wang, Amy K Y Fu, Nancy Y I. Instructive roles of astrocytes in hippocampal synaptic plasticity: neuronal activity-dependent regulatory mechanisms. The FEBS journal. 2021-05-11. PMID:33864430. |
such findings will clarify the roles of astrocytes in hippocampal synaptic plasticity and memory in health and disease. |
2021-05-11 |
2023-08-13 |
mouse |
Carlos J Rodriguez-Ortiz, Gilberto Aleph Prieto, Alessandra C Martini, Stefania Forner, Laura Trujillo-Estrada, Frank M LaFerla, David Baglietto-Vargas, Carl W Cotman, Masashi Kitazaw. miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease. Aging cell. vol 19. issue 3. 2021-05-10. PMID:32087004. |
mir-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of alzheimer's disease. |
2021-05-10 |
2023-08-13 |
mouse |
Vladimirs Pilipenko, Karīna Narbute, Jolanta Pupure, Ilva Kristiāna Langrate, Ruta Muceniece, Vija Kluš. Neuroprotective potential of antihyperglycemic drug metformin in streptozocin-induced rat model of sporadic Alzheimer's disease. European journal of pharmacology. vol 881. 2021-05-10. PMID:32580040. |
metformin also preserved hippocampal synaptic plasticity and normalized acetylcholine cleavage in the cortical and hippocampal tissues, as well as inhibited acetylcholine esterase activity in vitro. |
2021-05-10 |
2023-08-13 |
rat |
Guang Chen, Gang Yu, Zheng Yong, Hui Yan, Ruibin Su, Huijun Wan. A large dose of methamphetamine inhibits drug‑evoked synaptic plasticity via ER stress in the hippocampus. Molecular medicine reports. vol 23. issue 4. 2021-05-10. PMID:33576466. |
a large dose of methamphetamine inhibits drug‑evoked synaptic plasticity via er stress in the hippocampus. |
2021-05-10 |
2023-08-13 |
mouse |
Christopher G Sinon, Amy Ottensmeyer, Austin N Slone, Dan C Li, Rachael S Allen, Machelle T Pardue, Paul S Garcí. Prehabilitative exercise hastens recovery from isoflurane in diabetic and non-diabetic rats. Neuroscience letters. vol 751. 2021-05-10. PMID:33705936. |
postsynaptic density protein-95 (psd-95), an important scaffolding protein required for synaptic plasticity, protein levels were quantified from hippocampus using western blot. |
2021-05-10 |
2023-08-13 |
rat |
X-X Wang, B Zhang, R Xia, Q-Y Ji. Inflammation, apoptosis and autophagy as critical players in vascular dementia. European review for medical and pharmacological sciences. vol 24. issue 18. 2021-05-07. PMID:33015803. |
the deregulated autophagy pathway causes neuronal loss, hippocampal shrinkage, and ultimate loss in synaptic plasticity. |
2021-05-07 |
2023-08-13 |
Not clear |
Alex Sonneborn, Robert W Green. Norepinephrine transporter antagonism prevents dopamine-dependent synaptic plasticity in the mouse dorsal hippocampus. Neuroscience letters. vol 740. 2021-05-07. PMID:33127445. |
norepinephrine transporter antagonism prevents dopamine-dependent synaptic plasticity in the mouse dorsal hippocampus. |
2021-05-07 |
2023-08-13 |
mouse |
Andriana Koutsoumpa, Costas Papatheodoropoulo. Frequency-dependent layer-specific differences in short-term synaptic plasticity in the dorsal and ventral CA1 hippocampal field. Synapse (New York, N.Y.). vol 75. issue 7. 2021-05-07. PMID:33687106. |
frequency-dependent layer-specific differences in short-term synaptic plasticity in the dorsal and ventral ca1 hippocampal field. |
2021-05-07 |
2023-08-13 |
Not clear |
Kyungdeok Kim, Wangyong Shin, Muwon Kang, Suho Lee, Doyoun Kim, Ryeonghwa Kang, Yewon Jung, Yisul Cho, Esther Yang, Hyun Kim, Yong Chul Bae, Eunjoon Ki. Presynaptic PTPσ regulates postsynaptic NMDA receptor function through direct adhesion-independent mechanisms. eLife. vol 9. 2021-05-04. PMID:32142410. |
here we report that presynaptic ptpσ, a lar-rptp, enhances postsynaptic nmda receptor (nmdar) currents and nmdar-dependent synaptic plasticity in the hippocampus. |
2021-05-04 |
2023-08-13 |
mouse |
Ye Wang, Wing-Yu Fu, Kit Cheung, Kwok-Wang Hung, Congping Chen, Hongyan Geng, Wing-Ho Yung, Jianan Y Qu, Amy K Y Fu, Nancy Y I. Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 1. 2021-04-30. PMID:33443211. |
astrocyte-secreted il-33 mediates homeostatic synaptic plasticity in the adult hippocampus. |
2021-04-30 |
2023-08-13 |
mouse |
Ye Wang, Wing-Yu Fu, Kit Cheung, Kwok-Wang Hung, Congping Chen, Hongyan Geng, Wing-Ho Yung, Jianan Y Qu, Amy K Y Fu, Nancy Y I. Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 1. 2021-04-30. PMID:33443211. |
hippocampal synaptic plasticity is important for learning and memory formation. |
2021-04-30 |
2023-08-13 |
mouse |
Ye Wang, Wing-Yu Fu, Kit Cheung, Kwok-Wang Hung, Congping Chen, Hongyan Geng, Wing-Ho Yung, Jianan Y Qu, Amy K Y Fu, Nancy Y I. Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 1. 2021-04-30. PMID:33443211. |
these results collectively reveal an important role of astrocytic il-33 in mediating the negative-feedback signaling mechanism in homeostatic synaptic plasticity, providing insights into how astrocytes maintain hippocampal network homeostasis. |
2021-04-30 |
2023-08-13 |
mouse |
Seyed Asaad Karimi, Somayeh Komaki, Masoumeh Taheri, Ghazaleh Omidi, Masoumeh Kourosh-Arami, Iraj Salehi, Alireza Komak. Effects of the hydroalcoholic extract of Rosa damascena on hippocampal long-term potentiation in rats fed high-fat diet. The journal of physiological sciences : JPS. vol 71. issue 1. 2021-04-30. PMID:33926383. |
consumption of hfd is associated with reduction in hippocampal synaptic plasticity. |
2021-04-30 |
2023-08-13 |
rat |