| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Brandt, L Fester, G M Run. Neural sex steroids and hippocampal synaptic plasticity. Vitamins and hormones. vol 114. 2021-06-21. PMID:32723541. |
it was a widely held belief that sex steroids, namely testosterone and 17β-estradiol (e2) of gonadal origin, control synaptic plasticity in the hippocampus. |
2021-06-21 |
2023-08-13 |
Not clear |
| N Brandt, L Fester, G M Run. Neural sex steroids and hippocampal synaptic plasticity. Vitamins and hormones. vol 114. 2021-06-21. PMID:32723541. |
the inhibition of sex steroids in the hippocampus impairs synaptic plasticity sex-dependently in this region of the brain. |
2021-06-21 |
2023-08-13 |
Not clear |
| b' Ivana Grkovi\\xc4\\x87, Nata\\xc5\\xa1a Mitrovi\\xc4\\x8. Estradiol induces synaptic rearrangements. Vitamins and hormones. vol 114. 2021-06-21. PMID:32723546.' |
in this chapter, we highlighted the essential background concerning the effects of e2 on synaptic rearrangements accompanied by synaptic plasticity in e2-sensitive brain regions that mediate learning and memory, i.e., cortex and hippocampus. |
2021-06-21 |
2023-08-13 |
Not clear |
| Susanna Rizzi, Carlotta Spagnoli, Grazia Gabriella Salerno, Daniele Frattini, Stefano Giuseppe Caraffi, Gabriele Trimarchi, Claudio Moratti, Rosario Pascarella, Livia Garavelli, Carlo Fusc. Severe intellectual disability, absence of language, epilepsy, microcephaly and progressive cerebellar atrophy related to the recurrent de novo variant p.(P139L) of the CAMK2B gene: A case report and brief review. American journal of medical genetics. Part A. vol 182. issue 11. 2021-06-21. PMID:32875707. |
the camk2b gene encodes the β-subunit of calcium/calmodulin-dependent protein kinase ii (camk2), an enzyme that has crucial roles in synaptic plasticity, especially in hippocampal and cerebellar neurons. |
2021-06-21 |
2023-08-13 |
Not clear |
| Benjamin L Thompson, Marlene Oscar-Berman, Gary B Kapla. Opioid-induced structural and functional plasticity of medium-spiny neurons in the nucleus accumbens. Neuroscience and biobehavioral reviews. vol 120. 2021-06-21. PMID:33152423. |
additionally, glutamatergic neurons from the prefrontal cortex, the basolateral amygdala, the hippocampus, and the thalamus project to these same msns, providing an enriched target for synaptic plasticity. |
2021-06-21 |
2023-08-13 |
Not clear |
| Zeinab Momeni, Maricris Bautista, Joseph Neapetung, Rylan Urban, Yasuhiko Yamamoto, Anand Krishnan, Verónica A Campanucc. RAGE signaling is required for AMPA receptor dysfunction in the hippocampus of hyperglycemic mice. Physiology & behavior. vol 229. 2021-06-21. PMID:33221393. |
in rodent animal models, cognitive dysfunction can manifest as impaired hippocampal synaptic plasticity. |
2021-06-21 |
2023-08-13 |
mouse |
| Zeinab Momeni, Joseph Neapetung, Anthony Pacholko, Tabitha Achan Bol Kiir, Yasuhiko Yamamoto, Lane K Bekar, Verónica A Campanucc. Hyperglycemia induces RAGE-dependent hippocampal spatial memory impairments. Physiology & behavior. vol 229. 2021-06-21. PMID:33316294. |
changes in hippocampal synaptic plasticity and subsequent impairment in cognitive functions such as learning and memory, are well documented in animal models of type 1 and type 2 diabetes. |
2021-06-21 |
2023-08-13 |
mouse |
| Xiujun Qin, Liang Li, Xiaohan Nie, Qiao Ni. Effects of Chronic Aluminum Lactate Exposure on Neuronal Apoptosis and Hippocampal Synaptic Plasticity in Rats. Biological trace element research. vol 197. issue 2. 2021-06-18. PMID:31845204. |
effects of chronic aluminum lactate exposure on neuronal apoptosis and hippocampal synaptic plasticity in rats. |
2021-06-18 |
2023-08-13 |
rat |
| Xiujun Qin, Liang Li, Xiaohan Nie, Qiao Ni. Effects of Chronic Aluminum Lactate Exposure on Neuronal Apoptosis and Hippocampal Synaptic Plasticity in Rats. Biological trace element research. vol 197. issue 2. 2021-06-18. PMID:31845204. |
this study investigated the effects of chronic aluminum exposure on apoptosis of hippocampal neurons, and synaptic plasticity in the hippocampus in rats. |
2021-06-18 |
2023-08-13 |
rat |
| Xiujun Qin, Liang Li, Xiaohan Nie, Qiao Ni. Effects of Chronic Aluminum Lactate Exposure on Neuronal Apoptosis and Hippocampal Synaptic Plasticity in Rats. Biological trace element research. vol 197. issue 2. 2021-06-18. PMID:31845204. |
long-term exposure to aluminum could induce the apoptosis of hippocampal neurons, damage the synaptic plasticity, and impair the learning and memory functions in rats. |
2021-06-18 |
2023-08-13 |
rat |
| Crystal M Wilkie, Jocelyn R Barnes, Cherry-Lynn M Benson, Kyle J Brymer, Firoozeh Nafar, Matthew P Parson. Hippocampal Synaptic Dysfunction in a Mouse Model of Huntington Disease Is Not Alleviated by Ceftriaxone Treatment. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32354757. |
using electrophysiology and high-speed imaging of the glutamate biosensor iglusnfr, we quantified real-time glutamate dynamics and synaptic plasticity in the hippocampus of the q175fdn mouse model of hd, following intraperitoneal injections of either saline or ceftriaxone. |
2021-06-18 |
2023-08-13 |
mouse |
| A Ahnaou, T Broadbelt, R Biermans, H Huysmans, N V Manyakov, W H I M Drinkenbur. The phosphodiesterase-4 and glycine transporter-1 inhibitors enhance in vivo hippocampal theta network connectivity and synaptic plasticity, whereas D-serine does not. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32555167. |
the phosphodiesterase-4 and glycine transporter-1 inhibitors enhance in vivo hippocampal theta network connectivity and synaptic plasticity, whereas d-serine does not. |
2021-06-18 |
2023-08-13 |
rat |
| Jing Dong, Hui Fu, Yuanyuan Fu, Mingdan You, Xudong Li, Chaonan Wang, Kunkun Leng, Yuan Wang, Jie Che. Maternal Exposure to Di-(2-ethylhexyl) Phthalate Impairs Hippocampal Synaptic Plasticity in Male Offspring: Involvement of Damage to Dendritic Spine Development. ACS chemical neuroscience. vol 12. issue 2. 2021-06-18. PMID:33411500. |
maternal exposure to di-(2-ethylhexyl) phthalate impairs hippocampal synaptic plasticity in male offspring: involvement of damage to dendritic spine development. |
2021-06-18 |
2023-08-13 |
rat |
| Jing Dong, Hui Fu, Yuanyuan Fu, Mingdan You, Xudong Li, Chaonan Wang, Kunkun Leng, Yuan Wang, Jie Che. Maternal Exposure to Di-(2-ethylhexyl) Phthalate Impairs Hippocampal Synaptic Plasticity in Male Offspring: Involvement of Damage to Dendritic Spine Development. ACS chemical neuroscience. vol 12. issue 2. 2021-06-18. PMID:33411500. |
we studied the effects and possible mechanisms of maternal dehp treatment on hippocampal synaptic plasticity in offspring. |
2021-06-18 |
2023-08-13 |
rat |
| Jing Dong, Hui Fu, Yuanyuan Fu, Mingdan You, Xudong Li, Chaonan Wang, Kunkun Leng, Yuan Wang, Jie Che. Maternal Exposure to Di-(2-ethylhexyl) Phthalate Impairs Hippocampal Synaptic Plasticity in Male Offspring: Involvement of Damage to Dendritic Spine Development. ACS chemical neuroscience. vol 12. issue 2. 2021-06-18. PMID:33411500. |
our data showed that dehp exposure impaired hippocampal synaptic plasticity, damaged synaptic ultrastructure, and decreased synaptic protein levels in male pups. |
2021-06-18 |
2023-08-13 |
rat |
| Jing Dong, Hui Fu, Yuanyuan Fu, Mingdan You, Xudong Li, Chaonan Wang, Kunkun Leng, Yuan Wang, Jie Che. Maternal Exposure to Di-(2-ethylhexyl) Phthalate Impairs Hippocampal Synaptic Plasticity in Male Offspring: Involvement of Damage to Dendritic Spine Development. ACS chemical neuroscience. vol 12. issue 2. 2021-06-18. PMID:33411500. |
these results illustrate that maternal dehp exposure could impair hippocampal synaptic plasticity by affecting synaptic structure and dendritic spine development in male offspring, which may be attributed to altered cytoskeleton construction induced by downregulation of the rac1/pak/limk1/cofilin signaling pathway. |
2021-06-18 |
2023-08-13 |
rat |
| Zuo Zhang, Hongli Zhou, Jiyin Zho. Neuritin inhibits astrogliosis to ameliorate diabetic cognitive dysfunction. Journal of molecular endocrinology. vol 66. issue 4. 2021-06-16. PMID:33729996. |
neuritin overexpression in the hippocampus of db/db mice significantly ameliorated cognitive dysfunction, hippocampal neuronal impairment, and synaptic plasticity deterioration, and inhibited astrogliosis and the jak2/stat3 signaling pathway in the hippocampus. |
2021-06-16 |
2023-08-13 |
mouse |
| Idriss Ali Abdoulaye, Shan-Shan Wu, Enkhmurun Chibaatar, Da-Fan Yu, Kai Le, Xue-Jin Cao, Yi-Jing Gu. Ketamine Induces Lasting Antidepressant Effects by Modulating the NMDAR/CaMKII-Mediated Synaptic Plasticity of the Hippocampal Dentate Gyrus in Depressive Stroke Model. Neural plasticity. vol 2021. 2021-06-15. PMID:33981335. |
ketamine induces lasting antidepressant effects by modulating the nmdar/camkii-mediated synaptic plasticity of the hippocampal dentate gyrus in depressive stroke model. |
2021-06-15 |
2023-08-13 |
Not clear |
| Carey Wilson, Jake Rogers, Feng Chen, Shanshan Li, Paul A Adlard, Anthony J Hannan, Thibault Renoi. Exercise ameliorates aberrant synaptic plasticity without enhancing adult-born cell survival in the hippocampus of serotonin transporter knockout mice. Brain structure & function. vol 226. issue 6. 2021-06-15. PMID:34052925. |
exercise ameliorates aberrant synaptic plasticity without enhancing adult-born cell survival in the hippocampus of serotonin transporter knockout mice. |
2021-06-15 |
2023-08-13 |
mouse |
| Carey Wilson, Jake Rogers, Feng Chen, Shanshan Li, Paul A Adlard, Anthony J Hannan, Thibault Renoi. Exercise ameliorates aberrant synaptic plasticity without enhancing adult-born cell survival in the hippocampus of serotonin transporter knockout mice. Brain structure & function. vol 226. issue 6. 2021-06-15. PMID:34052925. |
deficits in hippocampal cellular and synaptic plasticity are frequently associated with cognitive and mood disorders, and indeed common mechanisms of antidepressants are thought to involve neuroplastic processes. |
2021-06-15 |
2023-08-13 |
mouse |