| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Boaz Mohar, Gabriela Michel, Yi-Zhi Wang, Veronica Hernandez, Jonathan B Grimm, Jin-Yong Park, Ronak Patel, Morgan Clarke, Timothy A Brown, Cornelius Bergmann, Kamil K Gebis, Anika P Wilen, Bian Liu, Richard Johnson, Austin Graves, Tatjana Tchumatchenko, Jeffrey N Savas, Eugenio F Fornasiero, Richard L Huganir, Paul W Tillberg, Luke D Lavis, Karel Svoboda, Nelson Sprusto. DELTA: a method for brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning. Nature neuroscience. 2025-03-31. PMID:40164741. |
during associative learning, the turnover of the ionotropic glutamate receptor subunit glua2, an indicator of synaptic plasticity, was enhanced in several brain regions, most markedly hippocampal area ca1. |
2025-03-31 |
2025-04-03 |
mouse |
| Keke Hao, Fashuai Chen, Shilin Xu, Ying Xiong, Rui Xu, Huan Huang, Chang Shu, Yisheng Lv, Gaohua Wang, Huiling Wan. Cognitive impairment following maternal separation in rats mediated by the NAD Translational psychiatry. vol 15. issue 1. 2025-03-31. PMID:40159484. |
our results suggest a causal role for the nad+/sirt3 axis in modulating cognitive behaviors via effects on hippocampal neuronal synaptic plasticity. |
2025-03-31 |
2025-04-03 |
rat |
| Shoma Izumi, Ibuki Kawasaki, Fuka Waki, Keisuke Nishikawa, Naoya Nishitani, Satoshi Deyama, Katsuyuki Kaned. Chronic nicotine enhances object recognition memory via inducing long-term potentiation in the medial prefrontal cortex in mice. Neuropharmacology. vol 273. 2025-03-30. PMID:40154943. |
in this study, we used a novel object recognition (nor) test and in vitro slice electrophysiology in mice to investigate the involvement of the medial prefrontal cortex (mpfc), a brain region connected to the hippocampus, and the synaptic plasticity within this region in chronic nicotine-induced object recognition memory enhancement. |
2025-03-30 |
2025-04-01 |
mouse |
| Cristina Rosell-Cardona, Michael K Collins, Kenneth J O'Riordan, Michael S Goodson, Nancy Kelley-Loughnane, John F Cryan, Gerard Clark. Acute Stress Enhances Synaptic Plasticity in Male Mice via a Microbiota-Dependent Mechanism. Neuropharmacology. 2025-03-28. PMID:40154944. |
in addition, alterations of hippocampal synaptic plasticity markers were noted. |
2025-03-28 |
2025-04-01 |
mouse |
| Maryam Radahmadi, Alireza Halabian, Arshia Halabia. An overview of extracellular field potentials: Different potentiation and measurable components, interpretations, and hippocampal synaptic activity models. Methods (San Diego, Calif.). 2025-03-27. PMID:40147603. |
the hippocampus and some other brain regions are critically involved in synaptic plasticity. |
2025-03-27 |
2025-03-30 |
Not clear |
| Carolyn Nicole Brown, Fan-Yi Chao, Daphne Quang, Nicole L Rumian, Mason S Kleinjan, Steven J Coultrap, K Ulrich Baye. Aβ impairs the LTP-related movement of endogenous CaMKII but not of exogenous GFP-CaMKII. Molecular biology of the cell. 2025-03-26. PMID:40137857. |
amyloid β (aβ) inhibits hippocampal long-term potentiation (ltp; a form of synaptic plasticity thought to underly learning and memory) by inhibiting the stimulation-induced synaptic accumulation of the ca |
2025-03-26 |
2025-03-30 |
Not clear |
| Antoine D Madar, Anqi Jiang, Can Dong, Mark E J Sheffiel. Synaptic plasticity rules driving representational shifting in the hippocampus. Nature neuroscience. 2025-03-21. PMID:40113934. |
synaptic plasticity rules driving representational shifting in the hippocampus. |
2025-03-21 |
2025-03-23 |
mouse |
| Araceli Bergadà-Martínez, Lucía de Los Reyes-Ramírez, Sara Martínez-Torres, Laura Ciaran-Alfano, Irene Martínez-Gallego, Rafael Maldonado, Antonio Rodríguez-Moreno, Andrés Ozait. Sub-chronic administration of AM6545 enhances cognitive performance and induces hippocampal synaptic plasticity changes in naïve mice. British journal of pharmacology. 2025-03-19. PMID:40102206. |
sub-chronic administration of am6545 enhances cognitive performance and induces hippocampal synaptic plasticity changes in naïve mice. |
2025-03-19 |
2025-03-21 |
mouse |
| Kyle A Brown, Musa I Ajibola, Todd D Goul. Rapid hippocampal synaptic potentiation induced by ketamine metabolite (2R,6R)-hydroxynorketamine persistently primes synaptic plasticity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2025-03-18. PMID:40097740. |
rapid hippocampal synaptic potentiation induced by ketamine metabolite (2r,6r)-hydroxynorketamine persistently primes synaptic plasticity. |
2025-03-18 |
2025-03-20 |
mouse |
| Olivia R Buonarati, Nidia Quillinan, K Ulrich Baye. Oxygen/glucose-deprivation causes long-term impairment of synaptic CaMKII movement. bioRxiv : the preprint server for biology. 2025-03-17. PMID:40093100. |
learning and memory are thought to require hippocampal long-term potentiation (ltp), a form of synaptic plasticity that is persistently impaired after cerebral ischemia and that requires movement of the ca |
2025-03-17 |
2025-03-20 |
Not clear |
| Weijie Yi, Emma Sylvester, Jiamei Lian, Chao Den. The effects of risperidone and voluntary exercise intervention on synaptic plasticity gene expressions in the hippocampus and prefrontal cortex of juvenile female rats. Physiology & behavior. 2025-03-17. PMID:40096936. |
the effects of risperidone and voluntary exercise intervention on synaptic plasticity gene expressions in the hippocampus and prefrontal cortex of juvenile female rats. |
2025-03-17 |
2025-03-20 |
rat |
| Kevin M Keary, Zheng L. Protocol for preparing mouse hippocampal slices for ex vivo recordings of the temporoammonic pathway. STAR protocols. vol 6. issue 2. 2025-03-15. PMID:40088452. |
the temporoammonic pathway (tap), the direct input from the entorhinal cortex to the hippocampus, is an important model structure for investigating synaptic plasticity. |
2025-03-15 |
2025-03-18 |
mouse |
| Lilit Darbinyan, Karen Simonyan, Lilia Hambardzumyan, Larisa Manukyan, Kristine Karapetyan, Margarita Danielya. Impact of L-thyroxine on hippocampal activity, morphology, and behavioral performance in thyroidectomized rats. Metabolic brain disease. vol 40. issue 3. 2025-03-10. PMID:40063269. |
results revealed significant changes in hippocampal electrophysiological responses in the l-thyroxine-treated group, including enhanced synaptic plasticity, increased excitatory activity, and more frequent, synchronized neuronal firing in the ca1 and ca3 regions. |
2025-03-10 |
2025-03-13 |
rat |
| Tanja Fuchsberger, Imogen Stockwell, Matty Woods, Zuzanna Brzosko, Ingo H Greger, Ole Paulse. Dopamine increases protein synthesis in hippocampal neurons enabling dopamine-dependent LTP. eLife. vol 13. 2025-03-10. PMID:40063079. |
the reward and novelty-related neuromodulator dopamine plays an important role in hippocampal long-term memory, which is thought to involve protein-synthesis-dependent synaptic plasticity. |
2025-03-10 |
2025-03-12 |
mouse |
| Si-Yu Huang, Zhi-Jun Yang, Jin Cheng, Hang-Yu Li, Si Chen, Zi-Hui Huang, Jie-Dong Chen, Ruo-Gu Xiong, Meng-Tao Yang, Chen Wang, Meng-Chu Li, Shuang Song, Wen-Ge Huang, Dong-Liang Wang, Hua-Bin Li, Qiu-Ye La. Choline alleviates cognitive impairment in sleep-deprived young mice via reducing neuroinflammation and altering phospholipidomic profile. Redox biology. vol 81. 2025-03-08. PMID:40056720. |
choline also reduces inflammation and oxidative stress biomarkers, and mitigates microglial activation in the hippocampus, which preserves synaptic plasticity. |
2025-03-08 |
2025-03-11 |
mouse |
| Jill C Flannery, Parker S Tirrell, Nina E Baumgartner, Jill M Danie. Neuroestrogens, the hippocampus, and female cognitive aging. Hormones and behavior. vol 170. 2025-03-04. PMID:40036999. |
these brain-derived neuroestrogens act in the hippocampus to regulate dendritic spine dynamics and synaptic plasticity as well as hippocampus-dependent memory. |
2025-03-04 |
2025-03-07 |
Not clear |
| Wei Zhou, Pengqi Li, Wen Meng, Stephanie Hong Zheng, Shixiong Zhang, Shasha Yi, Minghui Gao, Zhengrong Li. Selective sub-nucleus ultrasound stimulation induces synaptic potentiation in the mouse hippocampus. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. vol PP. 2025-03-03. PMID:40031237. |
in this study, we developed a miniature, high target-specificity ultrasound neuro-stimulation chip to selectively stimulate sub-nucleus and investigate the synaptic plasticity induced by ultrasound stimulation in mouse hippocampal slices. |
2025-03-03 |
2025-03-06 |
mouse |
| Linlin Zhang, Yanzhong Liu, Xin Wang, Hao Wu, Jiahui Xie, Yiping Li. Treadmill exercise ameliorates hippocampal synaptic injury and recognition memory deficits by TREM2 in AD rat model. Brain research bulletin. 2025-02-27. PMID:40015348. |
here, we aim to explore whether physical exercise pretreatment alters aβ-induced recognition memory impairment in structural synaptic plasticity within the hippocampus in ad rats. |
2025-02-27 |
2025-03-02 |
rat |
| Lihong Su, Jinchao Hou, Boxuan Wang, Yuqi Li, Xiaodong Huo, Tao Wang, Yuankang Zou, Gang Zhen. Mitofilin-mtDNA Axis Mediates Chronic Lead Exposure-Induced Synaptic Plasticity Impairment of Hippocampal and Cognitive Deficits. Biomolecules. vol 15. issue 2. 2025-02-26. PMID:40001575. |
mitofilin-mtdna axis mediates chronic lead exposure-induced synaptic plasticity impairment of hippocampal and cognitive deficits. |
2025-02-26 |
2025-02-28 |
mouse |
| Lihong Su, Jinchao Hou, Boxuan Wang, Yuqi Li, Xiaodong Huo, Tao Wang, Yuankang Zou, Gang Zhen. Mitofilin-mtDNA Axis Mediates Chronic Lead Exposure-Induced Synaptic Plasticity Impairment of Hippocampal and Cognitive Deficits. Biomolecules. vol 15. issue 2. 2025-02-26. PMID:40001575. |
to elucidate the role and mechanism of the mitofilin-mtdna axis in hippocampal synaptic plasticity and learning and memory impairment induced by lead exposure, in this study, both in vivo and in vitro models were subjected to chronic lead exposure. |
2025-02-26 |
2025-02-28 |
mouse |