| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anoop Manakkadan, Dolly Krishnan, Sheila Rui Xia Ang, Sreedharan Sajikuma. Slow Release of Hydrogen Sulfide in CA1 Hippocampal Neurons Rescues Long-Term Synaptic Plasticity and Associativity in an Amyloid-β Induced Model of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2024-09-20. PMID:39302367. |
slow release of hydrogen sulfide in ca1 hippocampal neurons rescues long-term synaptic plasticity and associativity in an amyloid-β induced model of alzheimer's disease. |
2024-09-20 |
2024-09-22 |
mouse |
| Juan-Juan Jiao, Yang Hu, Yu-Jia Cui, Chun-Mei Tuo, Yi-Xuan Wang, Xin-Yi Li, Yi Zhang, Mei-Na W. Anisomycin alleviates cognitive impairments and pathological features in 3xTg-AD mice. Neuropharmacology. 2024-09-20. PMID:39303856. |
in the present study, anisomycin was intragastrically administrated to female triple-transgenic ad (3xtg-ad) model mice, then morris water maze test was used to observe the long-term spatial memory of mice, the in vivo hippocampal field potential recording was performed to evaluate the synaptic plasticity, the western blot and immunofluorescence were employed to detect pathological changes, and the bioinformatics analysis was used to predict the potential target of anisomycin exerting effects in ad. |
2024-09-20 |
2024-09-23 |
mouse |
| J J Rodríguez, E Gardenal, F Zallo, J Cabot, X Busquet. Early PSA-NCAM reduction in the dentate gyrus and impaired plasticity in the Alzheimer´s disease 3xTg-mice model. Acta histochemica. vol 126. issue 8. 2024-09-17. PMID:39288682. |
this result suggests an early effect of the disease in the progression of immature and pluripotent cells resulting in an ulterior and early diminution of neurogenesis and therefore an impaired hippocampal cellular and synaptic plasticity. |
2024-09-17 |
2024-09-20 |
mouse |
| Melissa Hernández-Frausto, Emilio J Galván, Carolina López-Rubalcav. Dopamine D1 receptors activation rescues hippocampal synaptic plasticity and cognitive impairments in the MK-801 neonatal schizophrenia model. Behavioural brain research. vol 476. 2024-09-15. PMID:39277140. |
dopamine d1 receptors activation rescues hippocampal synaptic plasticity and cognitive impairments in the mk-801 neonatal schizophrenia model. |
2024-09-15 |
2024-09-18 |
rat |
| Melissa Hernández-Frausto, Emilio J Galván, Carolina López-Rubalcav. Dopamine D1 receptors activation rescues hippocampal synaptic plasticity and cognitive impairments in the MK-801 neonatal schizophrenia model. Behavioural brain research. vol 476. 2024-09-15. PMID:39277140. |
we evaluated synaptic plasticity late-ltp and spatial memory consolidation in early adolescence and young adulthood using extracellular field recordings in acute hippocampal slices and the barnes maze task. |
2024-09-15 |
2024-09-18 |
rat |
| Nathaniel A Swift, Qian Yang, Hannah J Marshall, Xueyan Zhou, Adam Manuel, Bruce E Kemp, Gregory R Steinberg, Tao M. Suppression of neuronal AMPKβ2 isoform impairs recognition memory and synaptic plasticity. Neurobiology of disease. 2024-09-15. PMID:39278510. |
we found that ampkβ2 (but not β1) suppression resulted in impaired recognition memory, reduced hippocampal synaptic plasticity, and altered structure of hippocampal postsynaptic densities and dendritic spines. |
2024-09-15 |
2024-09-18 |
mouse |
| Shu Qing Zhang, Xiao Yu Wang, Shen Lin Liu, Ching Yuan Hu, Yong Hong Men. Phlorizin ameliorates cognitive and behavioral impairments via the microbiota-gut-brain axis in high-fat and high-fructose diet-induced obese male mice. Brain, behavior, and immunity. 2024-09-14. PMID:39277023. |
in addition, phlorizin improved the hffd-induced decrease in synaptic plasticity, neuroinflammation, and excessive activation of microglia in the hippocampus. |
2024-09-14 |
2024-09-18 |
mouse |
| Conor C Dorian, Jiannis Taxidis, Peyman Golshan. Non-spatial hippocampal behavioral timescale synaptic plasticity during working memory is gated by entorhinal inputs. bioRxiv : the preprint server for biology. 2024-09-10. PMID:39253411. |
non-spatial hippocampal behavioral timescale synaptic plasticity during working memory is gated by entorhinal inputs. |
2024-09-10 |
2024-09-13 |
mouse |
| Conor C Dorian, Jiannis Taxidis, Peyman Golshan. Non-spatial hippocampal behavioral timescale synaptic plasticity during working memory is gated by entorhinal inputs. bioRxiv : the preprint server for biology. 2024-09-10. PMID:39253411. |
behavioral timescale synaptic plasticity (btsp) is a form of synaptic potentiation where the occurrence of a single large plateau potential in ca1 hippocampal neurons leads to the formation of reliable place fields during spatial learning tasks. |
2024-09-10 |
2024-09-13 |
mouse |
| Conor C Dorian, Jiannis Taxidis, Peyman Golshan. Non-spatial hippocampal behavioral timescale synaptic plasticity during working memory is gated by entorhinal inputs. bioRxiv : the preprint server for biology. 2024-09-10. PMID:39253411. |
altogether, odor-specific information from lec and strong odor-timed activity from mec are crucial for driving btsp in ca1, which is a synaptic plasticity mechanism for generation of both spatial and non-spatial responses in the hippocampus that may play a role in explaining representational drift and one-shot learning of non-spatial information. |
2024-09-10 |
2024-09-13 |
mouse |
| Zixun Wang, Xinyu Hu, Zhongyi Wang, Jiaming Chen, Ling Wang, Changjiang Li, Jing Deng, Kuitao Yue, Lizhuo Wang, Yujia Kong, Lin Su. Corrigendum to "Ketamine alleviates PTSD like effect and improves hippocampal synaptic plasticity via regulation of GSK-3β/GR signaling of rats" [J. Psychiatr. Res. 178 (2024) 259-269]. Journal of psychiatric research. vol 179. 2024-09-07. PMID:39243569. |
corrigendum to "ketamine alleviates ptsd like effect and improves hippocampal synaptic plasticity via regulation of gsk-3β/gr signaling of rats" [j. psychiatr. |
2024-09-07 |
2024-09-10 |
rat |
| Qiaofeng Zhou, Xiying Guo, Tu Chen, Yumin Liu, Huimin Ji, Yixuan Sun, Xiaosong Yang, Changhan Ouyang, Xiufen Liu, Min Le. The neuroprotective role of celastrol on hippocampus in diabetic rats by inflammation restraint, insulin signaling adjustment, Aβ reduction and synaptic plasticity alternation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 179. 2024-09-04. PMID:39232386. |
the neuroprotective role of celastrol on hippocampus in diabetic rats by inflammation restraint, insulin signaling adjustment, aβ reduction and synaptic plasticity alternation. |
2024-09-04 |
2024-09-08 |
rat |
| Daniel Wolf, Maurilyn Ayon-Olivas, Michael Sendtne. BDNF-Regulated Modulation of Striatal Circuits and Implications for Parkinson's Disease and Dystonia. Biomedicines. vol 12. issue 8. 2024-08-29. PMID:39200225. |
activation of tropomyosin receptor kinase b (trkb) by bdnf is necessary for the induction of long-term potentiation (ltp), a form of synaptic plasticity, in the hippocampus and striatum. |
2024-08-29 |
2024-09-01 |
Not clear |
| Ruth A Singer, Veronika Rajchin, Kwanghoon Park, Nathaniel Heintz, Robert B Darnel. Opto-CLIP reveals dynamic FMRP regulation of mRNAs upon CA1 neuronal activation. bioRxiv : the preprint server for biology. 2024-08-26. PMID:39185177. |
since molecular studies have demonstrated that synaptic plasticity in ca1 excitatory hippocampal neurons is protein-synthesis dependent, together these observations have suggested a potential role for fmrp in synaptic plasticity in fxs. |
2024-08-26 |
2024-08-28 |
Not clear |
| Federico Tesler, Roberta Maria Lorenzi, Adam Ponzi, Claudia Casellato, Fulvia Palesi, Daniela Gandolfi, Claudia A M Gandini Wheeler Kingshott, Jonathan Mapelli, Egidio D'Angelo, Michele Migliore, Alain Destexh. Multiscale modeling of neuronal dynamics in hippocampus CA1. Frontiers in computational neuroscience. vol 18. 2024-08-21. PMID:39165754. |
then, we analyze the implementation of synaptic plasticity within our framework, a key aspect to study the role of hippocampus in learning and memory consolidation, and we demonstrate the capability of our framework to incorporate the variations at synaptic level. |
2024-08-21 |
2024-08-23 |
Not clear |
| Calvin Wong, Luis David Rodriguez-Hernandez, Kevin C Lister, Ning Gu, Weihua Cai, Mehdi Hooshmandi, Jonathan Fan, Nicole Brown, Vivienne Nguyen, Alfredo Ribeiro-da-Silva, Robert P Bonin, Arkady Khoutorsk. Targeting spinal mechanistic target of rapamycin complex 2 alleviates inflammatory and neuropathic pain. Brain : a journal of neurology. 2024-08-21. PMID:39167538. |
the mechanistic target of rapamycin complex 2 (mtorc2), a central signaling hub that modulates both actin-dependent structural changes and mtorc1-dependent mrna translation, plays key roles in hippocampal synaptic plasticity and memory formation. |
2024-08-21 |
2024-08-24 |
Not clear |
| Zixun Wang, Xinyu Hu, Zhongyi Wang, Jiaming Chen, Ling Wang, Changjiang Li, Jing Deng, Kuitao Yue, Lizhuo Wang, Yujia Kong, Lin Su. Ketamine alleviates PTSD-like effect and improves hippocampal synaptic plasticity via regulation of GSK-3β/GR signaling of rats. Journal of psychiatric research. vol 178. 2024-08-21. PMID:39167905. |
ketamine alleviates ptsd-like effect and improves hippocampal synaptic plasticity via regulation of gsk-3β/gr signaling of rats. |
2024-08-21 |
2024-08-24 |
rat |
| Al-Hassan Soliman Wadan, Muhammad Liaquat Raza, Nasrollah Moradiko. Synaptic modulation by coffee compounds: Insights into neural plasticity. Progress in brain research. vol 289. 2024-08-21. PMID:39168580. |
this chapter investigates how caffeine affects fluctuations in structure and function in the hippocampus formation and neocortical structure, regions known for their high synaptic plasticity profile. |
2024-08-21 |
2024-08-24 |
Not clear |
| Sergio López-García, Esperanza López-Merino, Alba Fernández-Rodrigo, Pablo Zamorano-González, Silvia Gutiérrez-Eisman, Raquel Jiménez-Sánchez, José A Esteba. PI3K couples long-term synaptic potentiation with cofilin recruitment and actin polymerization in dendritic spines via its regulatory subunit p85α. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-08-19. PMID:39158722. |
to investigate this issue, we targeted individual regulatory subunits of type i pi3ks in hippocampal neurons and employed a combination of electrophysiological, biochemical and imaging techniques to assess their role in synaptic plasticity. |
2024-08-19 |
2024-08-21 |
Not clear |
| Yucai Ye, Chaojing Fu, Yan Li, Junli Sun, Xinru Li, Shifan Chai, Shuo Li, Meng Hou, Hongyan Cai, Meina Wu, Zhaojun Wan. Alternate-day fasting improves cognitive and brain energy deficits by promoting ketone metabolism in the 3xTg mouse model of Alzheimer's disease. Experimental neurology. 2024-08-14. PMID:39142368. |
we found that adf increased circulating βohb concentrations in 3xtg mice, improved cognitive function, reduced anxiety-like behaviors, improved hippocampal synaptic plasticity, and reduced neuronal loss, aβ oligomers and tau hyperphosphorylation. |
2024-08-14 |
2024-08-17 |
mouse |