| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jun Zhu, Yueru Hou, Wan Li, Xin Wang, Fei Li, Nan Li, Yan Hu, Xuelian Wang, Shun-Nan G. miR-181a Expressed in the Dorsal Hippocampus Regulates the Reinstatement of Cocaine CPP by Targeting PRKAA1. Behavioural brain research. 2024-06-15. PMID:38878971. |
mir-181a, which is widely expressed in the hippocampus, acts as a regulator for synaptic plasticity, while its role in drug reinstatement is unclear. |
2024-06-15 |
2024-06-18 |
Not clear |
| Guilherme Shigueto Vilar Higa, Felipe José Costa Viana, José Francis-Oliveira, Emily Cruvinel, Thainá Soares Franchin, Tania Marcourakis, Henning Ulrich, Roberto De Pasqual. Serotonergic Neuromodulation of Synaptic Plasticity. Neuropharmacology. 2024-06-14. PMID:38876308. |
through a comparative analysis across three main forebrain structures-the hippocampus, amygdala, and prefrontal cortex, this review discusses the actions of 5-ht on synaptic plasticity, offering insights into its role as a neuromodulator involved in emotional and cognitive functions. |
2024-06-14 |
2024-06-17 |
Not clear |
| Xi Yu, Jun Guo, Yueyang Song, Bin Wei, Yajun Shi, Yan Zhao, Zejun Zhao, Qinqin Gao, Bin Wang, Miao Su. HDAC1/2/3-mediated downregulation of neurogranin is involved in cognitive impairment in offspring exposed to maternal subclinical hypothyroidism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 12. 2024-06-12. PMID:38865202. |
chip analysis revealed that h3k9ac on the neurogranin (ng) promoter was reduced in the hippocampus of the offspring of sch, with a significant reduction in ng protein, leading to reduced expression levels of synaptic plasticity markers psd95 (a membrane-associated protein in the postsynaptic density) and syn (synaptophysin, a specific marker for presynaptic terminals), and impaired synaptic plasticity. |
2024-06-12 |
2024-06-15 |
mouse |
| Hardy Hagena, Denise Manahan-Vaugha. Interplay of hippocampal long-term potentiation and long-term depression in enabling memory representations. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 379. issue 1906. 2024-06-10. PMID:38853558. |
hippocampal long-term potentiation (ltp) and long-term depression (ltd) are hebbian forms of synaptic plasticity that are widely believed to comprise the physiological correlates of associative learning. |
2024-06-10 |
2024-06-14 |
Not clear |
| Kuldeep Tripathi, Somoday Hazra, Joyeeta Dutta Hazra, Silvia Mandel, Ruchi Anunu, Martin Kriebel, Hansjurgen Volkmer, Gal Richter-Levi. Selective knockdown of GABAA-α2 subunit in the dorsal dentate gyrus in adulthood induces anxiety, learning and memory deficits and impairs synaptic plasticity. The European journal of neuroscience. 2024-06-10. PMID:38858171. |
given the high expression of gabaa α2 in the dentate gyrus (dg) sub-field of the hippocampus, we sought to examine whether manipulation of the α2 subunit in this area will evoke changes in emotional behaviour, memory and learning as well as in synaptic plasticity. |
2024-06-10 |
2024-06-14 |
rat |
| Yan Sun, Hailou Zhang, Ruiyi Liu, Yanqing Wang, Xiangrui Zhang, Rumin Huang, Boran Zhu, Haoxin W. Zexieyin formula alleviates Alzheimer's disease via post-synaptic CaMKII modulating AMPA receptor: Involved in promoting neurogenesis to strengthen synaptic plasticity in mice hippocampus. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 131. 2024-06-09. PMID:38852473. |
zexieyin formula alleviates alzheimer's disease via post-synaptic camkii modulating ampa receptor: involved in promoting neurogenesis to strengthen synaptic plasticity in mice hippocampus. |
2024-06-09 |
2024-06-14 |
mouse |
| Ana Belén Sanz-Martos, María Roca, Mariano Ruiz-Gayo, Nuria Del Olm. TRIBUTYRIN REVERSES THE DELETERIOUS EFFECT OF SATURATED FAT ON WORKING MEMORY AND SYNAPTIC PLASTICITY IN JUVENILE MICE: DIFFERENTIAL EFFECTS IN MALES AND FEMALES. European journal of pharmacology. 2024-06-09. PMID:38852700. |
our research group has shown that tributyrin (tb), a butyric acid prodrug, reverses deficits in spatial memory and modulates hippocampal synaptic plasticity. |
2024-06-09 |
2024-06-14 |
mouse |
| Ana Belén Sanz-Martos, María Roca, Mariano Ruiz-Gayo, Nuria Del Olm. TRIBUTYRIN REVERSES THE DELETERIOUS EFFECT OF SATURATED FAT ON WORKING MEMORY AND SYNAPTIC PLASTICITY IN JUVENILE MICE: DIFFERENTIAL EFFECTS IN MALES AND FEMALES. European journal of pharmacology. 2024-06-09. PMID:38852700. |
hippocampal expression of genes involved in glutamatergic transmission as well as synaptic plasticity (long-term potentiation -ltp- and long-term depression -ltd-) were also analyzed. |
2024-06-09 |
2024-06-14 |
mouse |
| Gabriel Reichert Blume, Luiz Fernando Freire Roye. Peripheral to brain and hippocampus crosstalk induced by exercise mediates cognitive and structural hippocampal adaptations. Life sciences. 2024-06-09. PMID:38852798. |
both learning and memory as well as other hippocampal functional-related changes such as neurogenesis, cell proliferation, dendrite morphology and synaptic plasticity are controlled by these exercise responsive peripheral proteins. |
2024-06-09 |
2024-06-14 |
Not clear |
| A K Titterness, E L Gräfe, C Acosta, C Rodriguez, J D Thomas, B R Christi. Developmental ethanol exposure produces deficits in long-term potentiation in vivo that persist following postnatal choline supplementation. Alcohol, clinical & experimental research. 2024-06-08. PMID:38850072. |
we examined whether there are related improvements in hippocampal synaptic plasticity in vivo. |
2024-06-08 |
2024-06-10 |
Not clear |
| Ayman Alzu'bi, Ejlal Abu-El-Rub, Fatimah Almahasneh, Lena Tahat, Rabaa Y Athamneh, Ramada Khasawneh, Hiba Alzoubi, Doaa S Ghorab, Rawan Almazari, Mazhar Salim Al Zoubi, Raed M Al-Zoub. Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice. Neurotoxicology. vol 103. 2024-06-08. PMID:38823587. |
these findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (bdnf), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. |
2024-06-08 |
2024-06-11 |
mouse |
| Yanli Zhang, Tian Li, Jie Miao, Zhina Zhang, Mingxuan Yang, Zhuoran Wang, Bo Yang, Jiawei Zhang, Haiting Li, Qiang Su, Junhong Gu. Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice. Neural regeneration research. vol 20. issue 2. 2024-06-06. PMID:38819065. |
additionally, injection of app/ps1 mice with an adeno-associated virus encoding ggt5 enhanced hippocampal synaptic plasticity and mitigated cognitive deficits. |
2024-06-06 |
2024-06-08 |
mouse |
| Kangyu Jin, Bing Chen, Shengyi Han, Jingyi Dong, Shangping Cheng, Bin Qin, Jing L. Repetitive Transcranial Magnetic Stimulation (rTMS) Improves Cognitive Impairment and Intestinal Microecological Dysfunction Induced by High-Fat Diet in Rats. Research (Washington, D.C.). vol 7. 2024-06-03. PMID:38826566. |
this was accompanied by an increase in the number of new neurons and the transcription level of genes related to synaptic plasticity (spindlin 1, synaptophysin, and postsynaptic protein-95) in the hippocampus. |
2024-06-03 |
2024-06-05 |
rat |
| Kyeong-No Yoon, Sun Yong Kim, Jungeun Ji, Yidan Cui, Qing-Ling Quan, Gunhyuk Park, Jang-Hee Oh, Ji Su Lee, Joon-Yong An, Jin Ho Chung, Yong-Seok Lee, Dong Hun Le. Chronic ultraviolet irradiation induces memory deficits via dysregulation of the dopamine pathway. Experimental & molecular medicine. 2024-06-02. PMID:38825641. |
in a mouse model, we observed that uv irradiation of the skin induces deficits in hippocampal memory, synaptic plasticity, and adult neurogenesis, as well as increased dopamine levels in the skin, adrenal glands, and brain. |
2024-06-02 |
2024-06-05 |
mouse |
| Hanlin Jiang, Yusuke Kimura, Shota Inoue, Changxin Li, Junpei Hatakeyama, Masahiro Wakayama, Daisuke Takamura, Hideki Moriyam. Effects of different exercise modes and intensities on cognitive performance, adult hippocampal neurogenesis, and synaptic plasticity in mice. Experimental brain research. 2024-05-28. PMID:38806710. |
effects of different exercise modes and intensities on cognitive performance, adult hippocampal neurogenesis, and synaptic plasticity in mice. |
2024-05-28 |
2024-06-03 |
mouse |
| Hanlin Jiang, Yusuke Kimura, Shota Inoue, Changxin Li, Junpei Hatakeyama, Masahiro Wakayama, Daisuke Takamura, Hideki Moriyam. Effects of different exercise modes and intensities on cognitive performance, adult hippocampal neurogenesis, and synaptic plasticity in mice. Experimental brain research. 2024-05-28. PMID:38806710. |
this study aimed to identify the effects of different exercise modes (aerobic and resistance) and intensities (low and high) on cognitive performance, adult hippocampal neurogenesis and synaptic plasticity in mice. |
2024-05-28 |
2024-06-03 |
mouse |
| Benedikt Grünewald, Jonathan Wickel, Nina Hahn, Vahid Rahmati, Hanna Rupp, Ha-Yeun Chung, Holger Haselmann, Anja S Strauss, Lars Schmidl, Nina Hempel, Lena Grünewald, Anja Urbach, Michael Bauer, Klaus V Toyka, Markus Blaess, Ralf A Claus, Rainer König, Christian Gei. Targeted rescue of synaptic plasticity improves cognitive decline in sepsis-associated encephalopathy. Molecular therapy : the journal of the American Society of Gene Therapy. 2024-05-24. PMID:38788710. |
we found long-lasting synaptic pathology in the hippocampus including defective long-term synaptic plasticity, reduction of mature neuronal dendritic spines, and severely affected excitatory neurotransmission. |
2024-05-24 |
2024-05-27 |
Not clear |
| Huize Chen, Chujun Deng, Zeyu Meng, Mengting Zhu, Ruoyu Yang, Jing Yuan, Shengxi Men. Combined Catalpol and Tetramethylpyrazine Promote Axonal Plasticity in Alzheimer's Disease by Inducing Astrocytes to Secrete Exosomes Carrying CDK5 mRNA and Regulating STAT3 Phosphorylation. Molecular neurobiology. 2024-05-24. PMID:38789892. |
the levels of cdk5, synaptic plasticity marker protein neurofilament 200 (nf200), and growth-associated protein 43 (gap-43) in the hippocampus of mice were compared in each group. |
2024-05-24 |
2024-05-27 |
mouse |
| Min Xiao, Peng-Fei Li, Xue-Jiao Ma, Xing-Ke Yan, Chong-Bing M. Research progress of acupuncture regulating ERK signaling pathway in the treatment of depression. Zhen ci yan jiu = Acupuncture research. vol 49. issue 5. 2024-05-19. PMID:38764124. |
future research could explore the relationship between the erk pathway and other pathways, investigate other brain regions besides the prefrontal cortex and hippocampus, examine differences in regulatory mechanisms between male and female patients, assess the effects of different acupuncture techniques on the erk pathway, and increase efforts to explore mechanism of synaptic plasticity regulation, so as to provide reference for the clinical application and mechanism sludy of acupuncture in depression treatment. |
2024-05-19 |
2024-05-27 |
Not clear |
| Hamid Shokati Basir, Naser Mirazi, Alireza Komaki, Abdolkarim Hossein. Cacao consumption improves passive avoidance memory impairment in a rat model of Alzheimer's disease: the role of hippocampal synaptic plasticity and oxidative stress. Frontiers in pharmacology. vol 15. 2024-05-18. PMID:38756381. |
cacao consumption improves passive avoidance memory impairment in a rat model of alzheimer's disease: the role of hippocampal synaptic plasticity and oxidative stress. |
2024-05-18 |
2024-05-27 |
rat |