| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A K Titterness, E L Gräfe, C Acosta, C Rodriguez, J D Thomas, B R Christi. Developmental ethanol exposure produces deficits in long-term potentiation in vivo that persist following postnatal choline supplementation. Alcohol, clinical & experimental research. 2024-06-08. PMID:38850072. |
we examined whether there are related improvements in hippocampal synaptic plasticity in vivo. |
2024-06-08 |
2024-06-10 |
Not clear |
| Ayman Alzu'bi, Ejlal Abu-El-Rub, Fatimah Almahasneh, Lena Tahat, Rabaa Y Athamneh, Ramada Khasawneh, Hiba Alzoubi, Doaa S Ghorab, Rawan Almazari, Mazhar Salim Al Zoubi, Raed M Al-Zoub. Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice. Neurotoxicology. vol 103. 2024-06-08. PMID:38823587. |
these findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (bdnf), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. |
2024-06-08 |
2024-06-11 |
mouse |
| Yanli Zhang, Tian Li, Jie Miao, Zhina Zhang, Mingxuan Yang, Zhuoran Wang, Bo Yang, Jiawei Zhang, Haiting Li, Qiang Su, Junhong Gu. Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice. Neural regeneration research. vol 20. issue 2. 2024-06-06. PMID:38819065. |
additionally, injection of app/ps1 mice with an adeno-associated virus encoding ggt5 enhanced hippocampal synaptic plasticity and mitigated cognitive deficits. |
2024-06-06 |
2024-06-08 |
mouse |
| Kangyu Jin, Bing Chen, Shengyi Han, Jingyi Dong, Shangping Cheng, Bin Qin, Jing L. Repetitive Transcranial Magnetic Stimulation (rTMS) Improves Cognitive Impairment and Intestinal Microecological Dysfunction Induced by High-Fat Diet in Rats. Research (Washington, D.C.). vol 7. 2024-06-03. PMID:38826566. |
this was accompanied by an increase in the number of new neurons and the transcription level of genes related to synaptic plasticity (spindlin 1, synaptophysin, and postsynaptic protein-95) in the hippocampus. |
2024-06-03 |
2024-06-05 |
rat |
| Kyeong-No Yoon, Sun Yong Kim, Jungeun Ji, Yidan Cui, Qing-Ling Quan, Gunhyuk Park, Jang-Hee Oh, Ji Su Lee, Joon-Yong An, Jin Ho Chung, Yong-Seok Lee, Dong Hun Le. Chronic ultraviolet irradiation induces memory deficits via dysregulation of the dopamine pathway. Experimental & molecular medicine. 2024-06-02. PMID:38825641. |
in a mouse model, we observed that uv irradiation of the skin induces deficits in hippocampal memory, synaptic plasticity, and adult neurogenesis, as well as increased dopamine levels in the skin, adrenal glands, and brain. |
2024-06-02 |
2024-06-05 |
mouse |
| Hanlin Jiang, Yusuke Kimura, Shota Inoue, Changxin Li, Junpei Hatakeyama, Masahiro Wakayama, Daisuke Takamura, Hideki Moriyam. Effects of different exercise modes and intensities on cognitive performance, adult hippocampal neurogenesis, and synaptic plasticity in mice. Experimental brain research. 2024-05-28. PMID:38806710. |
effects of different exercise modes and intensities on cognitive performance, adult hippocampal neurogenesis, and synaptic plasticity in mice. |
2024-05-28 |
2024-06-03 |
mouse |
| Hanlin Jiang, Yusuke Kimura, Shota Inoue, Changxin Li, Junpei Hatakeyama, Masahiro Wakayama, Daisuke Takamura, Hideki Moriyam. Effects of different exercise modes and intensities on cognitive performance, adult hippocampal neurogenesis, and synaptic plasticity in mice. Experimental brain research. 2024-05-28. PMID:38806710. |
this study aimed to identify the effects of different exercise modes (aerobic and resistance) and intensities (low and high) on cognitive performance, adult hippocampal neurogenesis and synaptic plasticity in mice. |
2024-05-28 |
2024-06-03 |
mouse |
| Benedikt Grünewald, Jonathan Wickel, Nina Hahn, Vahid Rahmati, Hanna Rupp, Ha-Yeun Chung, Holger Haselmann, Anja S Strauss, Lars Schmidl, Nina Hempel, Lena Grünewald, Anja Urbach, Michael Bauer, Klaus V Toyka, Markus Blaess, Ralf A Claus, Rainer König, Christian Gei. Targeted rescue of synaptic plasticity improves cognitive decline in sepsis-associated encephalopathy. Molecular therapy : the journal of the American Society of Gene Therapy. 2024-05-24. PMID:38788710. |
we found long-lasting synaptic pathology in the hippocampus including defective long-term synaptic plasticity, reduction of mature neuronal dendritic spines, and severely affected excitatory neurotransmission. |
2024-05-24 |
2024-05-27 |
Not clear |
| Huize Chen, Chujun Deng, Zeyu Meng, Mengting Zhu, Ruoyu Yang, Jing Yuan, Shengxi Men. Combined Catalpol and Tetramethylpyrazine Promote Axonal Plasticity in Alzheimer's Disease by Inducing Astrocytes to Secrete Exosomes Carrying CDK5 mRNA and Regulating STAT3 Phosphorylation. Molecular neurobiology. 2024-05-24. PMID:38789892. |
the levels of cdk5, synaptic plasticity marker protein neurofilament 200 (nf200), and growth-associated protein 43 (gap-43) in the hippocampus of mice were compared in each group. |
2024-05-24 |
2024-05-27 |
mouse |
| Min Xiao, Peng-Fei Li, Xue-Jiao Ma, Xing-Ke Yan, Chong-Bing M. Research progress of acupuncture regulating ERK signaling pathway in the treatment of depression. Zhen ci yan jiu = Acupuncture research. vol 49. issue 5. 2024-05-19. PMID:38764124. |
future research could explore the relationship between the erk pathway and other pathways, investigate other brain regions besides the prefrontal cortex and hippocampus, examine differences in regulatory mechanisms between male and female patients, assess the effects of different acupuncture techniques on the erk pathway, and increase efforts to explore mechanism of synaptic plasticity regulation, so as to provide reference for the clinical application and mechanism sludy of acupuncture in depression treatment. |
2024-05-19 |
2024-05-27 |
Not clear |
| Hamid Shokati Basir, Naser Mirazi, Alireza Komaki, Abdolkarim Hossein. Cacao consumption improves passive avoidance memory impairment in a rat model of Alzheimer's disease: the role of hippocampal synaptic plasticity and oxidative stress. Frontiers in pharmacology. vol 15. 2024-05-18. PMID:38756381. |
cacao consumption improves passive avoidance memory impairment in a rat model of alzheimer's disease: the role of hippocampal synaptic plasticity and oxidative stress. |
2024-05-18 |
2024-05-27 |
rat |
| Xiaowan Lin, Peng Ren, Ziyi Xue, Xiao Liu, Ying Cao, Tianzuo Li, Huihui Mia. Astrocytic GDNF Ameliorates Anesthesia and Surgery-induced Cognitive Impairment by Promoting Hippocampal Synaptic Plasticity in Aged Mice. Neurochemistry international. 2024-05-16. PMID:38750960. |
astrocytic gdnf ameliorates anesthesia and surgery-induced cognitive impairment by promoting hippocampal synaptic plasticity in aged mice. |
2024-05-16 |
2024-05-27 |
mouse |
| Xinxin Xu, Fangjuan Li, Chunhua Liu, Yue Wang, Zhuo Yang, Guoming Xie, Tao Zhan. Low-frequency repetitive transcranial magnetic stimulation alleviates abnormal behavior in valproic acid rat model of autism through rescuing synaptic plasticity and inhibiting neuroinflammation. Pharmacology, biochemistry, and behavior. 2024-05-11. PMID:38734150. |
in this study, we investigated the effect of low-frequency rtms on the autistic-like symptoms and explored if this neuroprotective effect was associated with synaptic plasticity and neuroinflammation in the hippocampus. |
2024-05-11 |
2024-05-27 |
rat |
| Xinxin Xu, Fangjuan Li, Chunhua Liu, Yue Wang, Zhuo Yang, Guoming Xie, Tao Zhan. Low-frequency repetitive transcranial magnetic stimulation alleviates abnormal behavior in valproic acid rat model of autism through rescuing synaptic plasticity and inhibiting neuroinflammation. Pharmacology, biochemistry, and behavior. 2024-05-11. PMID:38734150. |
synaptic plasticity deficits and the abnormality expression of synapse-associated proteins were found in the hippocampus of prenatal vpa-exposed rats. |
2024-05-11 |
2024-05-27 |
rat |
| Jiao Cheng, Lin Yuan, Shuwen Yu, Bing Gu, Qian Luo, Xixi Wang, Yijing Zhao, Chengcheng Gai, Tingting Li, Weiyang Liu, Zhen Wang, Dexiang Liu, Roger C M Ho, Cyrus S H H. Programmed cell death factor 4-mediated hippocampal synaptic plasticity is involved in early life stress and susceptibility to depression. Behavioural brain research. vol 468. 2024-05-11. PMID:38723677. |
programmed cell death factor 4-mediated hippocampal synaptic plasticity is involved in early life stress and susceptibility to depression. |
2024-05-11 |
2024-05-27 |
mouse |
| Sophia C Noel, Jeanne F Madranges, Jean-David M Gothié, Jessica Ewald, Austen J Milnerwood, Timothy E Kennedy, Marilyn E Scot. Maternal gastrointestinal nematode infection alters hippocampal neuroimmunity, promotes synaptic plasticity, and improves resistance to direct infection in offspring. Scientific reports. vol 14. issue 1. 2024-05-10. PMID:38730262. |
maternal gastrointestinal nematode infection alters hippocampal neuroimmunity, promotes synaptic plasticity, and improves resistance to direct infection in offspring. |
2024-05-10 |
2024-05-27 |
Not clear |
| David M Bannerman, Chris Barkus, Ahmed Eltokh. Behavioral Analysis of NMDAR Function in Rodents: Tests of Long-Term Spatial Memory. Methods in molecular biology (Clifton, N.J.). vol 2799. 2024-05-10. PMID:38727905. |
nmdar-dependent forms of synaptic plasticity in brain regions like the hippocampus are widely believed to provide the neural substrate for long-term associative memory formation. |
2024-05-10 |
2024-05-27 |
mouse |
| Chiara Lanzillotta, Monika Rataj Baniowska, Francesca Prestia, Chiara Sette, Valérie Nalesso, Marzia Perluigi, Eugenio Barone, Arnaud Duchon, Antonella Tramutola, Yann Herault, Fabio Di Domenic. Shaping down syndrome brain cognitive and molecular changes due to aging using adult animals from the Ts66Yah murine model. Neurobiology of disease. 2024-05-05. PMID:38705491. |
the evaluation of hippocampal molecular pathways in ts66yah mice, as effect of age, demonstrate the aberrant regulation of redox balance, proteostasis, stress response, metabolic pathways, programmed cell death and synaptic plasticity. |
2024-05-05 |
2024-05-08 |
mouse |
| Giota Tsotsokou, George Trompoukis, Costas Papatheodoropoulo. Muscarinic modulation of synaptic transmission and short-term plasticity in the dorsal and ventral hippocampus. Molecular and cellular neurosciences. 2024-05-04. PMID:38703973. |
using the m2 receptor antagonist gallamine and the m4 receptor antagonist tropicamide, we found that m2 receptors are involved in controlling basal synaptic transmission and short-term synaptic plasticity (stsp) in the ventral but not the dorsal hippocampus, while m4 receptors participate in modulating basal synaptic transmission and stsp in both segments of the hippocampus. |
2024-05-04 |
2024-05-07 |
rat |
| Giota Tsotsokou, George Trompoukis, Costas Papatheodoropoulo. Muscarinic modulation of synaptic transmission and short-term plasticity in the dorsal and ventral hippocampus. Molecular and cellular neurosciences. 2024-05-04. PMID:38703973. |
we conclude that muscarinic transmission modulates excitatory synaptic transmission and short-term synaptic plasticity along the entire rat hippocampus by acting through m4 receptors and recruiting m2 receptors only in the ventral hippocampus. |
2024-05-04 |
2024-05-07 |
rat |