Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Kai Zhuang, Lige Leng, Xiao Su, Shuzhong Wang, Yuemin Su, Yanbing Chen, Ziqi Yuan, Liu Zi, Jieyin Li, Wenting Xie, Sihan Yan, Yujun Xia, Han Wang, Huifang Li, Zhenyi Chen, Tifei Yuan, Jie Zhan. Menin Deficiency Induces Autism-Like Behaviors by Regulating Foxg1 Transcription and Participates in Foxg1-Related Encephalopathy. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024-04-06. PMID:38582517. |
the deficits observed in menin deficient mice are rescued by the over-expression of foxg1, leading to normalized spine growth and restoration of hippocampal synaptic plasticity. |
2024-04-06 |
2024-04-10 |
mouse |
Megha Bhat Agni, Pramukh Subrahmanya Hegde, Praveen Rai, Monika Sadananda, Damodara Gowda K . Astaxanthin and DHA Supplementation Modulates the Maternal Undernutrition-induced Impairment of Cognitive Behavior and Synaptic Plasticity in Adult Life of Offspring's -Exploring the Molecular Mechanism. Molecular neurobiology. 2024-04-05. PMID:38578356. |
in addition, we assessed the expression of genes in the hippocampus related to cognitive function and synaptic plasticity. |
2024-04-05 |
2024-04-07 |
rat |
Ming Wang, Binyuan Xu, Yangmei Xie, Ge Yao, Yinghui Che. Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis. Neurochemical research. 2024-03-30. PMID:38555337. |
immunofluorescence (if), golgi staining, and brain path clamping were also used to detect the synaptic plasticity of hippocampal neurons. |
2024-03-30 |
2024-04-02 |
rat |
Kushagra Nagori, Madhulika Pradhan, Mukesh Sharma, Ajazuddin, Hemant R Badwaik, Kartik T Nakhat. Current Progress on Central Cholinergic Receptors as Therapeutic Targets for Alzheimer's Disease. Current Alzheimer research. 2024-03-26. PMID:38529600. |
by modulating synaptic transmission and promoting synaptic plasticity, particularly in the hippocampus and cortex, ach plays a pivotal role in the regulation of learning and memory. |
2024-03-26 |
2024-03-28 |
Not clear |
Zhiyuan Wang, Bin Han, Jianjiao Qi, Xuelei Cao, Huali Gu, Jinping Su. Chuanzhitongluo capsule improves cognitive impairment in mice with chronic cerebral hypoperfusion via the cholinergic anti-inflammatory pathway. Experimental gerontology. vol 189. 2024-03-24. PMID:38522309. |
it also reduced neuroinflammation in the hippocampus and upregulated the choline acetyltransferase (chat) and α7 subunit-containing nicotinic acetylcholine receptor (α7nachr), which are in synaptic plasticity and neuronal development. |
2024-03-24 |
2024-03-27 |
mouse |
Anna M Bugaj, Nicolas Kunath, Vidar Langseth Saasen, Marion S Fernandez-Berrocal, Ana Vankova, Pål Sætrom, Magnar Bjørås, Jing Y. Dissecting Gene Expression Networks in the Developing Hippocampus through the Lens of NEIL3 Depletion. Progress in neurobiology. 2024-03-24. PMID:38522610. |
gene regulation in the hippocampus is fundamental for its development, synaptic plasticity, memory formation, and adaptability. |
2024-03-24 |
2024-03-27 |
mouse |
Sohrab Anvari, Mohammad Javan, Javad Mirnajafi-Zadeh, Yaghoub Fathollah. Repeated Morphine Exposure Alters Temporoamonic-CA1 Synaptic Plasticity in Male Rat Hippocampus. Neuroscience. 2024-03-21. PMID:38513764. |
repeated morphine exposure alters temporoamonic-ca1 synaptic plasticity in male rat hippocampus. |
2024-03-21 |
2024-03-24 |
rat |
Sohrab Anvari, Mohammad Javan, Javad Mirnajafi-Zadeh, Yaghoub Fathollah. Repeated Morphine Exposure Alters Temporoamonic-CA1 Synaptic Plasticity in Male Rat Hippocampus. Neuroscience. 2024-03-21. PMID:38513764. |
in this study, the electrophysiological and biochemical consequences of repeated exposure to morphine in male rats on glutamatergic synaptic transmission, synaptic plasticity, the expression of gaba receptors and glutamate receptors at the temporoammonic-ca1 synapse along the longitudinal axis of the hippocampus (dorsal, intermediate, ventral, dh, ih, vh, respectively) were investigated. |
2024-03-21 |
2024-03-24 |
rat |
Sohrab Anvari, Mohammad Javan, Javad Mirnajafi-Zadeh, Yaghoub Fathollah. Repeated Morphine Exposure Alters Temporoamonic-CA1 Synaptic Plasticity in Male Rat Hippocampus. Neuroscience. 2024-03-21. PMID:38513764. |
a distinct change in the short- and long-term synaptic plasticity along the hippocampus long axis due to repeated morphine exposure, partially mediated by a change in the expression profile of glutamatergic receptor subunits. |
2024-03-21 |
2024-03-24 |
rat |
Marat M Rvache. An operating principle of the cerebral cortex, and a cellular mechanism for attentional trial-and-error pattern learning and useful classification extraction. Frontiers in neural circuits. vol 18. 2024-03-20. PMID:38505865. |
we modify synaptic plasticity rules to align with behavioral time scale synaptic plasticity (btsp) observed in hippocampal area ca1, making the framework more biophysically and behaviorally plausible. |
2024-03-20 |
2024-03-23 |
Not clear |
Yutaro Nagasawa, Hiromi H Ueda, Haruka Kawabata, Hideji Murakosh. LOV2-based photoactivatable CaMKII and its application to single synapses: Local Optogenetics. Biophysics and physicobiology. vol 20. issue 2. 2024-03-18. PMID:38496236. |
to address this, we developed an optogenetic tool named photoactivatable camkii (pacamkii) by fusing a light-sensitive domain (lov2) to camkiiα, which is a protein abundantly expressed in neurons of the cerebrum and hippocampus and essential for synaptic plasticity. |
2024-03-18 |
2024-03-20 |
Not clear |
Yutaro Nagasawa, Hiromi H Ueda, Haruka Kawabata, Hideji Murakosh. LOV2-based photoactivatable CaMKII and its application to single synapses: Local Optogenetics. Biophysics and physicobiology. vol 20. issue 2. 2024-03-18. PMID:38496236. |
combining photoactivatable camkii with two-photon excitation, we successfully activated it in single spines, inducing synaptic plasticity (long-term potentiation) in hippocampal neurons. |
2024-03-18 |
2024-03-20 |
Not clear |
Hui Zhang, Yingqiao Niu, Peng Yuan, Wenbo Liu, Wei Zhu, Jie Su. Neuroligin1 in excitatory synapses contributes to long-term cognitive impairments after repeated neonatal sevoflurane exposures. Experimental neurology. 2024-03-17. PMID:38493982. |
neuroligin1 (nl1) is essential for normal excitatory transmission and long-term synaptic plasticity in the hippocampus of intact animals. |
2024-03-17 |
2024-03-20 |
rat |
Haoxuan Gao, Mi Tian, Xiaozhe Geng, Ji Zhao, Yanan Song, Bing Wu, Xueyan Tian, Yong Yang, Wensi Ni, Huifang Yan. Cyfluthrin exposure during pregnancy causes neurotoxicity in offspring-Ca Ecotoxicology and environmental safety. vol 274. 2024-03-16. PMID:38492481. |
we found that gestational cy exposure affected pregnancy outcomes and fetal development, and that offspring showed impairments in anxiety as well as learning and memory, accompanied by impairments in hippocampal synaptic ultrastructure and synaptic plasticity. |
2024-03-16 |
2024-03-19 |
Not clear |
Yuhui Deng, Xin Liang, Yue Li, Lin Jiang, Jin Wang, Jing Tang, Jing Li, Yuhan Xie, Kai Xiao, Peilin Zhu, Yijing Guo, Yanmin Luo, Yong Tan. PGC-1α in the hippocampus mediates depressive-like and stress-coping behaviours and regulates excitatory synapses in the dentate gyrus in mice. Neuropharmacology. 2024-03-16. PMID:38492883. |
decreased hippocampal synaptic plasticity is an important pathological change in stress-related mood disorders, including major depressive disorder. |
2024-03-16 |
2024-03-19 |
mouse |
Babak Khodaie, Elke Edelmann, Volkmar Leßman. Distinct GABAergic modulation of timing-dependent LTP in CA1 pyramidal neurons along the longitudinal axis of the mouse hippocampus. iScience. vol 27. issue 3. 2024-03-15. PMID:38487018. |
synaptic plasticity in the hippocampus underlies episodic memory formation, with dorsal hippocampus being instrumental for spatial memory whereas ventral hippocampus is crucial for emotional learning. |
2024-03-15 |
2024-03-17 |
mouse |
Saiying Wang, Haijun Zhang, Rui Liu, Peijun Han, Qi Yang, Caiyan Cheng, Yue Chen, Zheng Rong, Chang Su, Fei Li, Gaofei Wei, Minggao Zhao, Le Yan. Influenza A Virus PB1-F2 Induces Affective Disorder by Interfering Synaptic Plasticity in Hippocampal Dentate Gyrus. Molecular neurobiology. 2024-03-15. PMID:38488981. |
influenza a virus pb1-f2 induces affective disorder by interfering synaptic plasticity in hippocampal dentate gyrus. |
2024-03-15 |
2024-03-18 |
mouse |
Qian Tang, Ryota Ojiro, Shunsuke Ozawa, Xinyu Zou, Junta Nakahara, Tomohiro Nakao, Mihoko Koyanagi, Meilan Jin, Toshinori Yoshida, Makoto Shibutan. DNA methylation-altered genes in the rat hippocampal neurogenic niche after continuous exposure to amorphous curcumin. Journal of chemical neuroanatomy. 2024-03-15. PMID:38490283. |
rat offspring who are exposed to an amorphous formula of curcumin (cur) from the embryonic stage have anti-anxiety-like behaviors, enhanced fear extinction learning, and increased synaptic plasticity in the hippocampal dentate gyrus (dg). |
2024-03-15 |
2024-03-18 |
rat |
Claudia Sagheddu, Tamara Stojanovic, Shima Kouhnavardi, Artem Savchenko, Ahmed M Hussein, Marco Pistis, Francisco J Monje, Roberto Plasenzotti, Mohammed Aufy, Christian R Studenik, Jana Lubec, Gert Lube. Cognitive performance in aged rats is associated with differences in distinctive neuronal populations in the ventral tegmental area and altered synaptic plasticity in the hippocampus. Frontiers in aging neuroscience. vol 16. 2024-03-12. PMID:38469164. |
cognitive performance in aged rats is associated with differences in distinctive neuronal populations in the ventral tegmental area and altered synaptic plasticity in the hippocampus. |
2024-03-12 |
2024-03-14 |
rat |
Jianxiong Gui, Mingdan Xie, Lingman Wang, Bing Tian, Benke Liu, Hengsheng Chen, Li Cheng, Dishu Huang, Ziyao Han, Xiaoyue Yang, Jie Liu, Li Jian. Protective effects of docosahexaenoic acid supplementation on cognitive dysfunction and hippocampal synaptic plasticity impairment induced by early postnatal PM2.5 exposure in young rats. Naunyn-Schmiedeberg's archives of pharmacology. 2024-03-09. PMID:38459987. |
protective effects of docosahexaenoic acid supplementation on cognitive dysfunction and hippocampal synaptic plasticity impairment induced by early postnatal pm2.5 exposure in young rats. |
2024-03-09 |
2024-03-12 |
rat |