| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elina E Mäkinen, Sanna Lensu, Jan Wikgren, Satu Pekkala, Lauren G Koch, Steven L Britton, Miriam S Noki. Intrinsic running capacity associates with hippocampal electrophysiology and long-term potentiation in rats. Neuroscience letters. 2024-02-01. PMID:38301912. |
our previous findings indicate that rats selectively bred for low capacity for running (lcr) show less synaptic plasticity and more inflammation in the hippocampus and perform worse in tasks requiring flexible cognition than rats bred for high capacity for running (hcr). |
2024-02-01 |
2024-02-04 |
rat |
| Yanan Li, Qi Zhang, Xupeng Wang, Fang Xu, Junfang Niu, Juan Zhao, Qiujun Wan. IL-17A deficiency alleviates cerebral ischemia-reperfusion injury via activating ERK/MAPK pathway in hippocampal CA1 region. Brain research bulletin. 2024-02-01. PMID:38302069. |
together, our findings suggest that il-17a deficiency alleviates cir injury by activating the erk/mapk signaling pathway and enhancing hippocampal synaptic plasticity. |
2024-02-01 |
2024-02-04 |
mouse |
| Giota Tsotsokou, Vasiliki Kouri, Costas Papatheodoropoulo. α7 nicotinic acetylcholine receptors induce long-term synaptic enhancement in the dorsal but not ventral hippocampus. Synapse (New York, N.Y.). vol 78. issue 1. 2024-01-30. PMID:38287475. |
in contrast to the long-term synaptic plasticity, we found that α7nachrs did not modulate short-term synaptic plasticity in either the dorsal or the ventral hippocampus. |
2024-01-30 |
2024-02-01 |
rat |
| Eman S El-Shetry, Ibrahim Amin Ibrahim, Asmaa Mahde Kamel, Ola Ali Abdelwaha. Quercetin mitigates doxorubicin-induced neurodegenerative changes in the cerebral cortex and hippocampus of rats; insights to DNA damage, inflammation, synaptic plasticity. Tissue & cell. vol 87. 2024-01-29. PMID:38286061. |
quercetin mitigates doxorubicin-induced neurodegenerative changes in the cerebral cortex and hippocampus of rats; insights to dna damage, inflammation, synaptic plasticity. |
2024-01-29 |
2024-02-01 |
rat |
| Natalie L Wellard, Nicholas E Clifton, Elliott Rees, Kerrie L Thomas, Jeremy Hal. The Association of Hippocampal Long-Term Potentiation-Induced Gene Expression with Genetic Risk for Psychosis. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38256020. |
genomic studies focusing on the contribution of common and rare genetic variants of schizophrenia and bipolar disorder support the view that substantial risk is conferred through molecular pathways involved in synaptic plasticity in the neurons of cortical and subcortical brain regions, including the hippocampus. |
2024-01-23 |
2024-01-25 |
Not clear |
| Isaac Vingan, Victoria Sook Keng Tung, Shwetha Phatarpekar, A Iván Hernández, Oleg V Evgrafov, Juan Marcos Alarco. Spatially Resolved Transcriptomic Signatures of Hippocampal Subregions and bioRxiv : the preprint server for biology. 2024-01-23. PMID:38260257. |
we found that training induced differentially expressed genes (degs) in the ca1 and ca3 hippocampal subregions were enriched with genes involved in synaptic transmission and synaptic plasticity, while degs in the dentate gyrus (dg) were enriched with genes involved in energy balance and ribosomal function. |
2024-01-23 |
2024-01-25 |
Not clear |
| Pia Kruse, Gudrun Brandes, Hanna Hemeling, Zhong Huang, Christoph Wrede, Jan Hegermann, Andreas Vlachos, Maximilian Len. Synaptopodin Regulates Denervation-Induced Plasticity at Hippocampal Mossy Fiber Synapses. Cells. vol 13. issue 2. 2024-01-22. PMID:38247806. |
hence, synaptopodin and the spine apparatus organelle play a crucial role in regulating lesion-induced synaptic plasticity at hippocampal mossy fiber synapses. |
2024-01-22 |
2024-01-24 |
mouse |
| Daniel P Chapman, Sarah D Power, Stefano Vicini, Tomás J Ryan, Mark P Burn. Amnesia after repeated head impact is caused by impaired synaptic plasticity in the memory engram. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-01-16. PMID:38228367. |
in sham mice the hippocampal engram neurons exhibited synaptic plasticity, evident in amplified ampa:nmda ratio, enhanced ampa-weighted tau, and increased dendritic spine volume compared to non-engram neurons. |
2024-01-16 |
2024-01-19 |
mouse |
| Daniel P Chapman, Sarah D Power, Stefano Vicini, Tomás J Ryan, Mark P Burn. Amnesia after repeated head impact is caused by impaired synaptic plasticity in the memory engram. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-01-16. PMID:38228367. |
in contrast, although hfhi mice retained a comparable number of hippocampal engram neurons, these neurons did not undergo synaptic plasticity. |
2024-01-16 |
2024-01-19 |
mouse |
| Yuxin Wen, Jiawen Xu, Jiahong Shen, Zili Tang, Shuxin Li, Qun Zhang, Jiaqi Li, Jianliang Su. Esketamine Prevents Postoperative Emotional and Cognitive Dysfunction by Suppressing Microglial M1 Polarization and Regulating the BDNF-TrkB Pathway in Ageing Rats with Preoperative Sleep Disturbance. Molecular neurobiology. 2024-01-14. PMID:38221533. |
in addition, esketamine administration also reversed the impaired hippocampal synaptic plasticity which has been perturbed by sleep disturbance and surgery. |
2024-01-14 |
2024-01-17 |
rat |
| Fen Zhuge, Liujie Zheng, Yuxiang Pan, Liyang Ni, Zhengwei Fu, Junping Shi, Yinhua N. DPP-4 inhibition by linagliptin ameliorates age-related mild cognitive impairment by regulating microglia polarization in mice. Experimental neurology. 2024-01-10. PMID:38199510. |
both linagliptin and metformin enhanced cognitive ability, increased hippocampal synaptic plasticity and neurogenesis, and decreased age-related oxidative stress and inflammation by regulating microglia polarization in the hippocampus of middle-aged mice. |
2024-01-10 |
2024-01-13 |
mouse |
| He Huang, Ning Wang, Jia-Tao Lin, Yong-Kang Qiu, Wei-Feng Wu, Qiang Liu, Chen Chen, Hai-Bi Wang, Yan-Ping Liu, Wei Dong, Jie Wan, Hui Zheng, Cheng-Hua Zhou, Yu-Qing W. Repeated Ketamine Anesthesia during the Neonatal Period Impairs Hippocampal Neurogenesis and Long-Term Neurocognitive Function by Inhibiting Mfn2-Mediated Mitochondrial Fusion in Neural Stem Cells. Molecular neurobiology. 2024-01-10. PMID:38200350. |
preconditioning with lv-mfn2 improved long-term cognitive dysfunction after repeated neonatal ketamine exposure by reversing the inhibitory effect of ketamine on synaptic plasticity in the hippocampal dg. |
2024-01-10 |
2024-01-13 |
rat |
| He Huang, Ning Wang, Jia-Tao Lin, Yong-Kang Qiu, Wei-Feng Wu, Qiang Liu, Chen Chen, Hai-Bi Wang, Yan-Ping Liu, Wei Dong, Jie Wan, Hui Zheng, Cheng-Hua Zhou, Yu-Qing W. Repeated Ketamine Anesthesia during the Neonatal Period Impairs Hippocampal Neurogenesis and Long-Term Neurocognitive Function by Inhibiting Mfn2-Mediated Mitochondrial Fusion in Neural Stem Cells. Molecular neurobiology. 2024-01-10. PMID:38200350. |
the present findings demonstrated that mfn2-mediated mitochondrial fusion dysfunction plays a critical role in the impairment of long-term neurocognitive function and synaptic plasticity caused by repeated neonatal ketamine exposure by interfering with hippocampal neurogenesis. |
2024-01-10 |
2024-01-13 |
rat |
| Mariana Ramos-Brossier, David Romeo-Guitart, Fabien Lanté, Valérie Boitez, François Mailliet, Soham Saha, Manon Rivagorda, Eleni Siopi, Ivan Nemazanyy, Christine Leroy, Stéphanie Moriceau, Sarah Beck-Cormier, Patrice Codogno, Alain Buisson, Laurent Beck, Gérard Friedlander, Franck Our. Slc20a1 and Slc20a2 regulate neuronal plasticity and cognition independently of their phosphate transport ability. Cell death & disease. vol 15. issue 1. 2024-01-09. PMID:38195526. |
accordingly, using a combination of molecular, electrophysiological and behavioral analyses, we show that while pit-2 favors hippocampal neuronal branching and survival, pit-1 promotes synaptic plasticity. |
2024-01-09 |
2024-01-13 |
Not clear |
| Stefan Vestring, Alexandra Dorner, Jonas Scholliers, Konstantin Ehrenberger, Andrea Kiss, Luis Arenz, Alice Theiss, Paul Rossner, Sibylle Frase, Catherine Du Vinage, Elisabeth Wendler, Tsvetan Serchov, Katharina Domschke, Josef Bischofberger, Claus Norman. D-Cycloserine enhances the bidirectional range of NMDAR-dependent hippocampal synaptic plasticity. Translational psychiatry. vol 14. issue 1. 2024-01-09. PMID:38195548. |
d-cycloserine enhances the bidirectional range of nmdar-dependent hippocampal synaptic plasticity. |
2024-01-09 |
2024-01-13 |
rat |
| Stefan Vestring, Alexandra Dorner, Jonas Scholliers, Konstantin Ehrenberger, Andrea Kiss, Luis Arenz, Alice Theiss, Paul Rossner, Sibylle Frase, Catherine Du Vinage, Elisabeth Wendler, Tsvetan Serchov, Katharina Domschke, Josef Bischofberger, Claus Norman. D-Cycloserine enhances the bidirectional range of NMDAR-dependent hippocampal synaptic plasticity. Translational psychiatry. vol 14. issue 1. 2024-01-09. PMID:38195548. |
here, we comprehensively examined the modulation of different forms of synaptic plasticity in the hippocampus by dcs and its mechanism. |
2024-01-09 |
2024-01-13 |
rat |
| Stefan Vestring, Alexandra Dorner, Jonas Scholliers, Konstantin Ehrenberger, Andrea Kiss, Luis Arenz, Alice Theiss, Paul Rossner, Sibylle Frase, Catherine Du Vinage, Elisabeth Wendler, Tsvetan Serchov, Katharina Domschke, Josef Bischofberger, Claus Norman. D-Cycloserine enhances the bidirectional range of NMDAR-dependent hippocampal synaptic plasticity. Translational psychiatry. vol 14. issue 1. 2024-01-09. PMID:38195548. |
we found that dcs positively modulates nmdar-dependent forms of long-term synaptic plasticity (long-term synaptic potentiation, ltp, and long-term synaptic depression, ltd) in hippocampal brain slices of juvenile rats without affecting basal synaptic transmission. |
2024-01-09 |
2024-01-13 |
rat |
| Stefan Vestring, Alexandra Dorner, Jonas Scholliers, Konstantin Ehrenberger, Andrea Kiss, Luis Arenz, Alice Theiss, Paul Rossner, Sibylle Frase, Catherine Du Vinage, Elisabeth Wendler, Tsvetan Serchov, Katharina Domschke, Josef Bischofberger, Claus Norman. D-Cycloserine enhances the bidirectional range of NMDAR-dependent hippocampal synaptic plasticity. Translational psychiatry. vol 14. issue 1. 2024-01-09. PMID:38195548. |
functional eradication of astrocytes, inhibition of mglur1 receptors and g-protein signaling in astrocytes adjacent to postsynaptic neurons prevented the induction of nmdar-dependent forms of ltp and ltd. our results support the enhancement of a bidirectional range of nmdar-dependent hippocampal synaptic plasticity by dcs and d-serine-mediated gliotransmission. |
2024-01-09 |
2024-01-13 |
rat |
| Shahab Ghaderi, Parsa Gholipour, Alireza Komaki, Siamak Shahidi, Faezeh Seif, Mohammad Bahrami-Tapehebur, Iraj Salehi, Mohammad Zarei, Abdolrahman Sarihi, Masome Rashn. Underlying mechanisms behind the neuroprotective effect of vanillic acid against diabetes-associated cognitive decline: An in vivo study in a rat model. Phytotherapy research : PTR. 2024-01-08. PMID:38185917. |
long-term potentiation (ltp) was induced at hippocampal dentate gyrus (dg) synapses in response to high-frequency stimulation (hfs) applied to the perforant pathway (pp) to evaluate synaptic plasticity. |
2024-01-08 |
2024-01-10 |
rat |
| Zicheng Ling, Sirui Zhou, Yancheng Zhou, Wanyu Zhong, Zhonghao Su, Zhenxia Qi. Protective role of madecassoside from Centella asiatica against protein L-isoaspartyl methyltransferase deficiency-induced neurodegeneration. Neuropharmacology. 2024-01-05. PMID:38181970. |
aside from abnormal accumulation of l-isoasp, pimt knockout (ko) mice mirrors some neuropathological hallmarks such as anxiety-like behaviors, impaired spatial memory and aberrant synaptic plasticity in the hippocampus of neurodegenerative diseases (nds), including alzheimer's disease (ad) and related dementias, and parkinson's disease (pd). |
2024-01-05 |
2024-01-08 |
mouse |