| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stefan Vestring, Alexandra Dorner, Jonas Scholliers, Konstantin Ehrenberger, Andrea Kiss, Luis Arenz, Alice Theiss, Paul Rossner, Sibylle Frase, Catherine Du Vinage, Elisabeth Wendler, Tsvetan Serchov, Katharina Domschke, Josef Bischofberger, Claus Norman. D-Cycloserine enhances the bidirectional range of NMDAR-dependent hippocampal synaptic plasticity. Translational psychiatry. vol 14. issue 1. 2024-01-09. PMID:38195548. |
functional eradication of astrocytes, inhibition of mglur1 receptors and g-protein signaling in astrocytes adjacent to postsynaptic neurons prevented the induction of nmdar-dependent forms of ltp and ltd. our results support the enhancement of a bidirectional range of nmdar-dependent hippocampal synaptic plasticity by dcs and d-serine-mediated gliotransmission. |
2024-01-09 |
2024-01-13 |
rat |
| Shahab Ghaderi, Parsa Gholipour, Alireza Komaki, Siamak Shahidi, Faezeh Seif, Mohammad Bahrami-Tapehebur, Iraj Salehi, Mohammad Zarei, Abdolrahman Sarihi, Masome Rashn. Underlying mechanisms behind the neuroprotective effect of vanillic acid against diabetes-associated cognitive decline: An in vivo study in a rat model. Phytotherapy research : PTR. 2024-01-08. PMID:38185917. |
long-term potentiation (ltp) was induced at hippocampal dentate gyrus (dg) synapses in response to high-frequency stimulation (hfs) applied to the perforant pathway (pp) to evaluate synaptic plasticity. |
2024-01-08 |
2024-01-10 |
rat |
| Zicheng Ling, Sirui Zhou, Yancheng Zhou, Wanyu Zhong, Zhonghao Su, Zhenxia Qi. Protective role of madecassoside from Centella asiatica against protein L-isoaspartyl methyltransferase deficiency-induced neurodegeneration. Neuropharmacology. 2024-01-05. PMID:38181970. |
aside from abnormal accumulation of l-isoasp, pimt knockout (ko) mice mirrors some neuropathological hallmarks such as anxiety-like behaviors, impaired spatial memory and aberrant synaptic plasticity in the hippocampus of neurodegenerative diseases (nds), including alzheimer's disease (ad) and related dementias, and parkinson's disease (pd). |
2024-01-05 |
2024-01-08 |
mouse |
| Qiong Xiang, Jia-Sheng Tao, Chuan-Jun Fu, Li-Xiu Liao, Li-Ni Liu, Jing Deng, Xian-Hui L. The integrated analysis and underlying mechanisms of FNDC5 on diabetic induced cognitive deficits. International journal of geriatric psychiatry. vol 39. issue 1. 2024-01-01. PMID:38161286. |
chronic hyperglycemia is considered as an important factor to promote the neurodegenerative process of brain, and the synaptic plasticity as well as heterogeneity of hippocampal cells are thought to be associated with cognitive dysfunction in the early process of neurodegeneration. |
2024-01-01 |
2024-01-05 |
Not clear |
| . Retraction: Young plasma reverses anesthesia and surgery-induced cognitive impairment in aged rats by modulating hippocampal synaptic plasticity. Frontiers in aging neuroscience. vol 15. 2024-01-01. PMID:38161588. |
retraction: young plasma reverses anesthesia and surgery-induced cognitive impairment in aged rats by modulating hippocampal synaptic plasticity. |
2024-01-01 |
2024-01-05 |
rat |
| Daniela Sofia Abreu, Joana I Gomes, Filipa F Ribeiro, Maria J Diógenes, Ana M Sebastião, Sandra H Va. Astrocytes control hippocampal synaptic plasticity through the vesicular-dependent release of D-serine. Frontiers in cellular neuroscience. vol 17. 2023-12-25. PMID:38145284. |
astrocytes control hippocampal synaptic plasticity through the vesicular-dependent release of d-serine. |
2023-12-25 |
2023-12-27 |
Not clear |
| Lalit P Chandravanshi, Prashant Agrawal, Hany W Darwish, Surendra Kumar Trigu. Impairments of Spatial Memory and N-methyl-d-aspartate Receptors and Their Postsynaptic Signaling Molecules in the Hippocampus of Developing Rats Induced by As, Pb, and Mn Mixture Exposure. Brain sciences. vol 13. issue 12. 2023-12-23. PMID:38137163. |
the nmda receptor and several important signaling proteins are involved in learning, memory, and synaptic plasticity in the hippocampus, including camkii, postsynaptic density protein-95 (psd-95), synaptic ras gtpase activating protein (syngap), a negative regulator of ras-mapk activity, and creb. |
2023-12-23 |
2023-12-25 |
rat |
| Anđela Horvat, Ignacija Vlašić, Jasminka Štefulj, Nada Oršolić, Maja Jazvinšćak Jembre. Flavonols as a Potential Pharmacological Intervention for Alleviating Cognitive Decline in Diabetes: Evidence from Preclinical Studies. Life (Basel, Switzerland). vol 13. issue 12. 2023-12-23. PMID:38137892. |
diabetes mellitus is a complex metabolic disease associated with reduced synaptic plasticity, atrophy of the hippocampus, and cognitive decline. |
2023-12-23 |
2023-12-25 |
human |
| Magdalena Natalia Wojtas, Marta Diaz-González, Nadezhda Stavtseva, Yuval Shoam, Poonam Verma, Assaf Buberman, Inbar Izhak, Aria Geva, Roi Basch, Alberto Ouro, Lucia Perez-Benitez, Uri Levy, Erika Borcel, Ángel Nuñez, Cesar Venero, Noa Rotem-Dai, Isana Veksler-Lublinsky, Shira Knaf. Interplay between hippocampal TACR3 and systemic testosterone in regulating anxiety-associated synaptic plasticity. Molecular psychiatry. 2023-12-22. PMID:38135756. |
interplay between hippocampal tacr3 and systemic testosterone in regulating anxiety-associated synaptic plasticity. |
2023-12-22 |
2023-12-25 |
rat |
| Magdalena Natalia Wojtas, Marta Diaz-González, Nadezhda Stavtseva, Yuval Shoam, Poonam Verma, Assaf Buberman, Inbar Izhak, Aria Geva, Roi Basch, Alberto Ouro, Lucia Perez-Benitez, Uri Levy, Erika Borcel, Ángel Nuñez, Cesar Venero, Noa Rotem-Dai, Isana Veksler-Lublinsky, Shira Knaf. Interplay between hippocampal TACR3 and systemic testosterone in regulating anxiety-associated synaptic plasticity. Molecular psychiatry. 2023-12-22. PMID:38135756. |
hence, we have investigated the relationship between tacr3 expression, anxiety, sex hormones, and synaptic plasticity in a rat model, which indicated that severe anxiety is linked to dampened tacr3 expression in the ventral hippocampus. |
2023-12-22 |
2023-12-25 |
rat |
| Justinas J Dainauskas, Paola Vitale, Sebastien Moreno, Hélène Marie, Michele Migliore, Ausra Saudargien. Altered synaptic plasticity at hippocampal CA1-CA3 synapses in Alzheimer's disease: integration of amyloid precursor protein intracellular domain and amyloid beta effects into computational models. Frontiers in computational neuroscience. vol 17. 2023-12-22. PMID:38130706. |
altered synaptic plasticity at hippocampal ca1-ca3 synapses in alzheimer's disease: integration of amyloid precursor protein intracellular domain and amyloid beta effects into computational models. |
2023-12-22 |
2023-12-24 |
Not clear |
| Yongxin Xie, Ji Zhao, Xiaoyu Li, Jian Sun, Huifang Yan. Effects of Cyfluthrin Exposure on Neurobehaviour, Hippocampal Tissue and Synaptic Plasticity in Wistar Rats. Toxics. vol 11. issue 12. 2023-12-22. PMID:38133400. |
effects of cyfluthrin exposure on neurobehaviour, hippocampal tissue and synaptic plasticity in wistar rats. |
2023-12-22 |
2023-12-24 |
rat |
| Yongxin Xie, Ji Zhao, Xiaoyu Li, Jian Sun, Huifang Yan. Effects of Cyfluthrin Exposure on Neurobehaviour, Hippocampal Tissue and Synaptic Plasticity in Wistar Rats. Toxics. vol 11. issue 12. 2023-12-22. PMID:38133400. |
this experiment was conducted to study the effects of cyfluthrin (cy) exposure on neurobehaviour, hippocampal tissue and synaptic plasticity in wistar rats. |
2023-12-22 |
2023-12-24 |
rat |
| Bohye Kim, Joong-Sun Kim, BuHyun Youn, Changjong Moo. Dopamine depletion alters neuroplasticity-related signaling in the rat hippocampus. Animal cells and systems. vol 27. issue 1. 2023-12-21. PMID:38125760. |
dopamine (da) plays a significant role in regulating hippocampal function, particularly in modulating synaptic plasticity. |
2023-12-21 |
2023-12-23 |
rat |
| Cristina Lao-Peregrin, Guoqing Xiang, Jihye Kim, Ipsit Srivastava, Alexandra B Fall, Danielle M Gerhard, Piia Kohtala, Daegeon Kim, Minseok Song, Mikel Garcia-Marcos, Joshua Levitz, Francis S Le. Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk. Cell reports. vol 43. issue 1. 2023-12-20. PMID:38117654. |
we find that the receptor tyrosine kinase (rtk) trkb and the g-protein-coupled receptor (gpcr) metabotropic glutamate receptor 5 (mglur5) together mediate hippocampal synaptic plasticity in response to brain-derived neurotrophic factor (bdnf). |
2023-12-20 |
2023-12-23 |
Not clear |
| Tao Tong, Chongyao Hao, Junliang Shen, Siyu Liu, Simin Yan, Muhammad Shahzad Aslamc, Yiping Chen, Wenjie Chen, Jianguo Li, Yuhan Li, Jingyu Zeng, Meng Li, Zhuoran You, Tuergong Gulizhaerkezi, Simiao Wei, Anning Zhu, Xianjun Men. Electroacupuncture ameliorates chronic unpredictable mild stress-induced depression-like behavior and cognitive impairment through suppressing oxidative stress and neuroinflammation in rats. Brain research bulletin. 2023-12-20. PMID:38123022. |
yet few studies have directed acupuncture's mechanism toward enhancing axonal repair correlated with synaptic plasticity and anti-inflammatory effects related to oxidative stress in the hippocampus. |
2023-12-20 |
2023-12-23 |
rat |
| Xiaotong Wang, Wei Zheng, Ziyi Zhu, Biyu Xing, Weijie Yan, Ke Zhu, Lingli Xiao, Chaojuan Yang, Mengping Wei, Lei Yang, Zi-Bing Jin, Xueyun Bi, Chen Zhan. Timp1 Deletion Induces Anxiety-like Behavior in Mice. Neuroscience bulletin. 2023-12-19. PMID:38113013. |
brain synaptic plasticity may be regulated by tissue inhibitor of matrix metalloproteinase 1 (timp1), a known protein inhibitor of extracellular matrix (ecm), and the expression of timp1 in the hippocampus can be induced by neuronal excitation and various stimuli. |
2023-12-19 |
2023-12-23 |
mouse |
| Hong-Kun Wang, Jin-Ming He, Yue-Heng Yan, Zi-Hao Wang, Ruo-Xuan Li, Yan-Yan Wan. [Effect of Suanzaoren Decoction on expression of ionotropic glutamate receptors and synaptic plasticity in hippocampus of anxiety rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 20. 2023-12-19. PMID:38114151. |
[effect of suanzaoren decoction on expression of ionotropic glutamate receptors and synaptic plasticity in hippocampus of anxiety rats]. |
2023-12-19 |
2023-12-23 |
mouse |
| Hong-Kun Wang, Jin-Ming He, Yue-Heng Yan, Zi-Hao Wang, Ruo-Xuan Li, Yan-Yan Wan. [Effect of Suanzaoren Decoction on expression of ionotropic glutamate receptors and synaptic plasticity in hippocampus of anxiety rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 20. 2023-12-19. PMID:38114151. |
this study investigated the effect of suanzaoren decoction on the expression of n-methyl-d-aspartate receptors(nmdar) and α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptors(ampar) in the hippocampus and synaptic plasticity in rats with conditioned fear-induced anxiety. |
2023-12-19 |
2023-12-23 |
mouse |
| Xingyu Yang, Ziwei Yu, Li An, Xinyue Jing, Mengqian Yuan, Tiancheng Xu, Zhi Yu, Bin Xu, Mengjiang L. Electroacupuncture stimulation ameliorates cognitive impairment induced by long-term high-fat diet by regulating microglial BDNF. Brain research. vol 1825. 2023-12-17. PMID:38103878. |
western blotting was used to detect the expression levels of pro-inflammatory molecules il-1β and il-1r, synaptic plasticity related proteins synaptophysin and postsynaptic density-95 (psd-95), and apoptotic molecules (caspase-3 and bcl-2), in the hippocampus. |
2023-12-17 |
2023-12-21 |
mouse |