| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaolin Han, Shan Huang, Ziyun Zhuang, Xiaochen Zhang, Min Xie, Nengjun Lou, Mengyu Hua, Xianghua Zhuang, Shuyan Yu, Shihong Che. Phosphatidate phosphatase Lipin1 involves in diabetic encephalopathy pathogenesis via regulating synaptic mitochondrial dynamics. Redox biology. vol 69. 2023-12-16. PMID:38103341. |
knock-down of lipin1 within hippocampus of normal rats induces dysregulation of homeostasis in synaptic mitochondrial dynamics with an increase of mitochondrial fission and a decrease of fusion, then causes synaptic mitochondrial dysfunction, synaptic plasticity deficits as well as cognitive impairments, similar to that observed in response to chronic hyperglycemia exposure. |
2023-12-16 |
2023-12-21 |
rat |
| Jia-Hui Chen, Na Xu, Lei Qi, Hao-Hao Yan, Fang-Yan Wan, Feng Gao, Chuanhai Fu, Chunlei Cang, Boxun Lu, Guo-Qiang Bi, Ai-Hui Tan. Reduced lysosomal density in neuronal dendrites mediates deficits in synaptic plasticity in Huntington's disease. Cell reports. vol 42. issue 12. 2023-12-14. PMID:38096054. |
here, we discover a reduction in the dendritic density of lysosomes in the hippocampus that correlates with deficits in synaptic plasticity and spatial learning in early cag-140 hd model mice. |
2023-12-14 |
2023-12-17 |
mouse |
| Hajer El Oussini, Chun-Lei Zhang, Urielle François, Cecilia Castelli, Aurélie Lampin-Saint-Amaux, Marilyn Lepleux, Pablo Molle, Legeolas Velez, Cyril Dejean, Frederic Lanore, Cyril Herry, Daniel Choquet, Yann Humea. CA3 hippocampal synaptic plasticity supports ripple physiology during memory consolidation. Nature communications. vol 14. issue 1. 2023-12-14. PMID:38097535. |
ca3 hippocampal synaptic plasticity supports ripple physiology during memory consolidation. |
2023-12-14 |
2023-12-17 |
mouse |
| Hajer El Oussini, Chun-Lei Zhang, Urielle François, Cecilia Castelli, Aurélie Lampin-Saint-Amaux, Marilyn Lepleux, Pablo Molle, Legeolas Velez, Cyril Dejean, Frederic Lanore, Cyril Herry, Daniel Choquet, Yann Humea. CA3 hippocampal synaptic plasticity supports ripple physiology during memory consolidation. Nature communications. vol 14. issue 1. 2023-12-14. PMID:38097535. |
to tackle this question, we used cell surface ampar immobilisation to block post-synaptic ltp within the hippocampal region of male mice during a spatial memory task, and show that: 1- hippocampal synaptic plasticity is engaged during consolidation, but is dispensable during encoding or retrieval. |
2023-12-14 |
2023-12-17 |
mouse |
| Lei Dong, Tong Zhao, Zijia Jin, Yu Zhen. Effect of music rhythm magnetic field on long-term potentiation of hippocampal Schaffer-CA1 synapse plasticity. Neuroscience letters. 2023-12-12. PMID:38086521. |
the experimental results demonstrated that as the music frequency increased, the enhancing effect of the music rhythmic magnetic field on hippocampal synaptic plasticity ltp gradually intensified. |
2023-12-12 |
2023-12-17 |
rat |
| Chad M Heer, Mark E J Sheffiel. Distinct catecholaminergic pathways projecting to hippocampal CA1 transmit contrasting signals during behavior and learning. bioRxiv : the preprint server for biology. 2023-12-11. PMID:38076843. |
neuromodulatory inputs to the hippocampus play pivotal roles in modulating synaptic plasticity, shaping neuronal activity, and influencing learning and memory. |
2023-12-11 |
2023-12-17 |
mouse |
| Lei Dong, Ling Zhao, Lei Tian, Wenjun Zhao, Chan Xiong, Yu Zhen. AsHC 360 Exposure Influence on Epileptiform Discharges in Hippocampus of Infantile Male Rats In Vitro. International journal of molecular sciences. vol 24. issue 23. 2023-12-09. PMID:38069126. |
they can penetrate the blood-brain barrier, specifically affecting synaptic plasticity and the learning and memory ability of hippocampal neurons. |
2023-12-09 |
2023-12-17 |
rat |
| Xiao-Xiang Tan, Hong-Yu Dai, Juan Yao, Jia-Jia Wang, Yu-Chen Dai, Tian-Hao Zhang, Li-Li Qiu, Jie Su. Hippocampal estrogens rescued the decline of synaptic plasticity after surgery and anesthesia by inhibiting microglia overactivation. Behavioural brain research. 2023-12-06. PMID:38056710. |
hippocampal estrogens rescued the decline of synaptic plasticity after surgery and anesthesia by inhibiting microglia overactivation. |
2023-12-06 |
2023-12-10 |
Not clear |
| Xiao-Xiang Tan, Hong-Yu Dai, Juan Yao, Jia-Jia Wang, Yu-Chen Dai, Tian-Hao Zhang, Li-Li Qiu, Jie Su. Hippocampal estrogens rescued the decline of synaptic plasticity after surgery and anesthesia by inhibiting microglia overactivation. Behavioural brain research. 2023-12-06. PMID:38056710. |
this study aimed to determine whether suppressing microglia overactivation by hippocampal estrogens can rescue the decrease of synaptic plasticity after surgery and anesthesia. |
2023-12-06 |
2023-12-10 |
Not clear |
| Xiaoman Dai, Anlan Lin, Lvping Zhuang, Qingyong Zeng, Lili Cai, Yuanxiang Wei, Hongjie Liang, Weijie Gao, Jing Zhang, Xiaochun Che. Targeting SIK3 to modulate hippocampal synaptic plasticity and cognitive function by regulating the transcription of HDAC4 in a mouse model of Alzheimer's disease. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-12-06. PMID:38057370. |
targeting sik3 to modulate hippocampal synaptic plasticity and cognitive function by regulating the transcription of hdac4 in a mouse model of alzheimer's disease. |
2023-12-06 |
2023-12-10 |
mouse |
| Xiaoman Dai, Anlan Lin, Lvping Zhuang, Qingyong Zeng, Lili Cai, Yuanxiang Wei, Hongjie Liang, Weijie Gao, Jing Zhang, Xiaochun Che. Targeting SIK3 to modulate hippocampal synaptic plasticity and cognitive function by regulating the transcription of HDAC4 in a mouse model of Alzheimer's disease. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-12-06. PMID:38057370. |
conditional deletion of sik3 gene in dorsal hippocampal neurons of 5×fad mice further accelerated cognitive deterioration and impaired synaptic plasticity. |
2023-12-06 |
2023-12-10 |
mouse |
| Xiaoman Dai, Anlan Lin, Lvping Zhuang, Qingyong Zeng, Lili Cai, Yuanxiang Wei, Hongjie Liang, Weijie Gao, Jing Zhang, Xiaochun Che. Targeting SIK3 to modulate hippocampal synaptic plasticity and cognitive function by regulating the transcription of HDAC4 in a mouse model of Alzheimer's disease. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-12-06. PMID:38057370. |
moreover, up-regulation of slp-s, the truncated fragment of sik3, in dorsal hippocampal neurons, restored the synaptic plasticity and alleviates the cognitive impairment in 5×fad mice. |
2023-12-06 |
2023-12-10 |
mouse |
| Yuhan Wu, Zhanpeng Zhu, Tian Lan, Shuhan Li, Ye Li, Changmin Wang, Yabo Feng, Xueqin Mao, Shuyan Y. Levomilnacipran Improves Lipopolysaccharide-Induced Dysregulation of Synaptic Plasticity and Depression-Like Behaviors via Activating BDNF/TrkB Mediated PI3K/Akt/mTOR Signaling Pathway. Molecular neurobiology. 2023-12-06. PMID:38057644. |
significantly ameliorated depression-like behaviors in rats, alleviated the dysregulation of synaptic plasticity, and suppressed neuroinflammation within hippocampus induced by lps-treatment. |
2023-12-06 |
2023-12-10 |
rat |
| Yu Jin, Xue Li, Changling Wei, Qiongjia Yua. Effects of exercise-targeted hippocampal PDE-4 methylation on synaptic plasticity and spatial learning/memory impairments in D-galactose-induced aging rats. Experimental brain research. 2023-12-05. PMID:38052997. |
effects of exercise-targeted hippocampal pde-4 methylation on synaptic plasticity and spatial learning/memory impairments in d-galactose-induced aging rats. |
2023-12-05 |
2023-12-10 |
rat |
| Katharina Klinger, Miguel Del Ángel, Gürsel Çalışkan, Oliver Stor. Increasing NPYergic transmission in the hippocampus rescues aging-related deficits of long-term potentiation in the mouse dentate gyrus. Frontiers in aging neuroscience. vol 15. 2023-12-01. PMID:38020778. |
however, the interaction of these two neuromodulatory systems in maintaining hippocampal synaptic plasticity during healthy aging has not been explored so far. |
2023-12-01 |
2023-12-07 |
mouse |
| Katharina Klinger, Miguel Del Ángel, Gürsel Çalışkan, Oliver Stor. Increasing NPYergic transmission in the hippocampus rescues aging-related deficits of long-term potentiation in the mouse dentate gyrus. Frontiers in aging neuroscience. vol 15. 2023-12-01. PMID:38020778. |
however, the interaction of these two neuromodulatory systems in maintaining hippocampal synaptic plasticity during healthy aging has not been explored so far. |
2023-11-29 |
2023-12-07 |
mouse |
| Vijendra Sharma, Mauricio M Oliveira, Rapita Sood, Abdessattar Khlaifia, Danning Lou, Mehdi Hooshmandi, Tzu-Yu Hung, Niaz Mahmood, Maya Reeves, David Ho-Tieng, Noah Cohen, Po-Chieh Cheng, Mir Munir A Rahim, Masha Prager-Khoutorsky, Randal J Kaufman, Kobi Rosenblum, Jean-Claude Lacaille, Arkady Khoutorsky, Eric Klann, Nahum Sonenber. mRNA translation in astrocytes controls hippocampal long-term synaptic plasticity and memory. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 49. 2023-11-28. PMID:38015848. |
mrna translation in astrocytes controls hippocampal long-term synaptic plasticity and memory. |
2023-11-28 |
2023-12-07 |
Not clear |
| Vijendra Sharma, Mauricio M Oliveira, Rapita Sood, Abdessattar Khlaifia, Danning Lou, Mehdi Hooshmandi, Tzu-Yu Hung, Niaz Mahmood, Maya Reeves, David Ho-Tieng, Noah Cohen, Po-Chieh Cheng, Mir Munir A Rahim, Masha Prager-Khoutorsky, Randal J Kaufman, Kobi Rosenblum, Jean-Claude Lacaille, Arkady Khoutorsky, Eric Klann, Nahum Sonenber. mRNA translation in astrocytes controls hippocampal long-term synaptic plasticity and memory. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 49. 2023-11-28. PMID:38015848. |
thus, learning-induced dephosphorylation of eif2α in astrocytes bolsters hippocampal synaptic plasticity and consolidation of long-term memories. |
2023-11-28 |
2023-12-07 |
Not clear |
| P Duarte-Guterman, J E Richard, S E Lieblich, R S Eid, Y Lamers, L A M Gale. Cellular and molecular signatures of motherhood in the adult and ageing rat brain. Open biology. vol 13. issue 11. 2023-11-24. PMID:37989220. |
thus, previous parity has lasting effects on synaptic plasticity with fewer lasting effects on inflammation and cell signalling phosphoproteins in the whole hippocampus. |
2023-11-24 |
2023-11-28 |
rat |
| Fen Liu, Qing Tian, Hui-Ling Tang, Xiang Cheng, Wei Zou, Ping Zhan. Hydrogen sulfide attenuates depression-like behaviours in Parkinson's disease model rats by improving synaptic plasticity in a hippocampal Warburg effect-dependent manner. Pharmacology, biochemistry, and behavior. 2023-11-15. PMID:37967673. |
hydrogen sulfide attenuates depression-like behaviours in parkinson's disease model rats by improving synaptic plasticity in a hippocampal warburg effect-dependent manner. |
2023-11-15 |
2023-11-20 |
rat |