| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Melih Tarhan, Tim Hartl, Olena Shchyglo, Jens Colitti-Klausnitzer, Angela Kuhla, Tobias Maximilian Breuer, Denise Manahan-Vaugha. Changes in hippocampal volume, synaptic plasticity and amylin sensitivity in an animal model of type 2 diabetes are associated with increased vulnerability to amyloid-beta in advancing age. Frontiers in aging neuroscience. vol 16. 2024-07-08. PMID:38974903. |
changes in hippocampal volume, synaptic plasticity and amylin sensitivity in an animal model of type 2 diabetes are associated with increased vulnerability to amyloid-beta in advancing age. |
2024-07-08 |
2024-07-11 |
Not clear |
| Naif H Ali, Hayder M Al-Kuraishy, Ali I Al-Gareeb, Najah R Hadi, Abdullah A Assiri, Mohammed Alrouji, Nermeen N Welson, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batih. Hypoglycemia and Alzheimer Disease Risk: The Possible Role of Dasiglucagon. Cellular and molecular neurobiology. vol 44. issue 1. 2024-07-08. PMID:38977507. |
glucagon/glp-1 has been shown to promote synaptogenesis, hippocampal synaptic plasticity, and learning and memory, while attenuating amyloid and tau pathologies. |
2024-07-08 |
2024-07-12 |
Not clear |
| Roland Tresky, Yuta Miyamoto, Yu Nagayoshi, Yasushi Yabuki, Kimi Araki, Yukie Takahashi, Yoshihiro Komohara, Huicong Ge, Kayo Nishiguchi, Takaichi Fukuda, Hitomi Kaneko, Nobuko Maeda, Jin Matsuura, Shintaro Iwasaki, Kourin Sakakida, Norifumi Shioda, Fan-Yan Wei, Kazuhito Tomizawa, Takeshi Chuj. TRMT10A dysfunction perturbs codon translation of initiator methionine and glutamine and impairs brain functions in mice. Nucleic acids research. 2024-07-01. PMID:38950903. |
despite not showing discernable defects in the pancreas, liver, or kidney, trmt10a null mice showed lower body weight and smaller hippocampal postsynaptic densities, which is associated with defective synaptic plasticity and memory. |
2024-07-01 |
2024-07-04 |
mouse |
| Ga-Young Choi, In-Seo Lee, Eunyoung Moon, Hyosung Choi, A Reum Je, Ji-Ho Park, Hee-Seok Kweo. Ameliorative effect of vanillic acid against scopolamine-induced learning and memory impairment in rat via attenuation of oxidative stress and dysfunctional synaptic plasticity. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 177. 2024-06-28. PMID:38941895. |
additionally, the measurement of long-term potentiation was used to determine the function of synaptic plasticity in organotypic hippocampal slice cultures. |
2024-06-28 |
2024-07-01 |
rat |
| Ga-Young Choi, In-Seo Lee, Eunyoung Moon, Hyosung Choi, A Reum Je, Ji-Ho Park, Hee-Seok Kweo. Ameliorative effect of vanillic acid against scopolamine-induced learning and memory impairment in rat via attenuation of oxidative stress and dysfunctional synaptic plasticity. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 177. 2024-06-28. PMID:38941895. |
the study's findings suggest that va has a neuroprotective effect on scop-induced learning and memory impairment linked to the hippocampal cholinergic system, oxidative damage, and synaptic plasticity. |
2024-06-28 |
2024-07-01 |
rat |
| Norman Holl, Marco Heerdegen, Volker Zschorlich, Rüdiger Köhling, Timo Kirschstei. Inhibition of Acute mGluR5-Dependent Depression in Hippocampal CA1 by High-Frequency Magnetic Stimulation. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928603. |
high-frequency magnetic stimulation (hfms) applied directly to the hippocampal slice preparation in vitro induces activity-dependent synaptic plasticity and metaplasticity. |
2024-06-27 |
2024-06-29 |
Not clear |
| Emilija Glavonic, Milorad Dragic, Milos Mitic, Minja Aleksic, Iva Lukic, Sanja Ivkovic, Miroslav Adzi. Ketamine's Amelioration of Fear Extinction in Adolescent Male Mice Is Associated with the Activation of the Hippocampal Akt-mTOR-GluA1 Pathway. Pharmaceuticals (Basel, Switzerland). vol 17. issue 6. 2024-06-27. PMID:38931336. |
we analyzed the protein and gene expression of synaptic plasticity markers in the hippocampus (hpc) and prefrontal cortex (pfc) and sought to identify neural correlates associated with ketamine's effects on adolescent extinction learning. |
2024-06-27 |
2024-06-29 |
mouse |
| Felipe C Ribeiro, Danielle Cozachenco, Elentina K Argyrousi, Agnieszka Staniszewski, Shane Wiebe, Joao D Calixtro, Rubens Soares-Neto, Aycheh Al-Chami, Fatema El Sayegh, Sara Bermudez, Emily Arsenault, Marcelo Cossenza, Jean-Claude Lacaille, Karim Nader, Hongyu Sun, Fernanda G De Felice, Mychael V Lourenco, Ottavio Arancio, Argel Aguilar-Valles, Nahum Sonenberg, Sergio T Ferreir. The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-06-27. PMID:38934107. |
the ketamine metabolite (2r,6r)-hydroxynorketamine rescues hippocampal mrna translation, synaptic plasticity and memory in mouse models of alzheimer's disease. |
2024-06-27 |
2024-06-29 |
mouse |
| Baoyue Zhang, Jun Zhao, Caiqin Yan, Yiming Bai, Pengfei Guo, Chao Wang, Zhe Wang, Guanhua Du, Ailin Li. Combination of RNA-seq and proteomics reveals the mechanism of DL0410 treatment in APP/PS1 transgenic mouse model of Alzheimer's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 177. 2024-06-26. PMID:38925020. |
dl0410 significantly reduced β-amyloid deposition and resulted in significant upregulation of synaptophysin, psd95 and nmdar/ camkⅡ signaling pathway in the hippocampus and cortex, indicating that dl0410 improved synaptic plasticity in app/ps1 mice, which agrees with the results of rna-seq and proteomics. |
2024-06-26 |
2024-06-29 |
mouse |
| Kevin D Phelan, U Thaung Shwe, Hong Wu, Fang Zhen. Investigating Contributions of Canonical Transient Receptor Potential Channel 3 to Hippocampal Hyperexcitability and Seizure-Induced Neuronal Cell Death. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38892448. |
in this study, we investigated the contribution of trpc3 channels to the electrophysiological properties of hippocampal pyramidal neurons and hippocampal synaptic plasticity, and the contribution of trpc3 channels to seizure-induced neuronal cell death. |
2024-06-19 |
2024-06-21 |
Not clear |
| Kyung-Jun Boo, Dae Hyun Kim, Eunbi Cho, Dong Hyun Kim, Se Jin Jeon, Chan Young Shi. Neonatal dysregulation of 2-arachidonoylglycerol induces impaired brain function in adult mice. Neuropharmacology. 2024-06-17. PMID:38885736. |
do34-injected mice showed significantly decreased cognitive functions, attributed to impairment of hippocampal synaptic plasticity. |
2024-06-17 |
2024-06-21 |
mouse |
| Jun Zhu, Yueru Hou, Wan Li, Xin Wang, Fei Li, Nan Li, Yan Hu, Xuelian Wang, Shun-Nan G. miR-181a Expressed in the Dorsal Hippocampus Regulates the Reinstatement of Cocaine CPP by Targeting PRKAA1. Behavioural brain research. 2024-06-15. PMID:38878971. |
mir-181a, which is widely expressed in the hippocampus, acts as a regulator for synaptic plasticity, while its role in drug reinstatement is unclear. |
2024-06-15 |
2024-06-18 |
Not clear |
| Guilherme Shigueto Vilar Higa, Felipe José Costa Viana, José Francis-Oliveira, Emily Cruvinel, Thainá Soares Franchin, Tania Marcourakis, Henning Ulrich, Roberto De Pasqual. Serotonergic Neuromodulation of Synaptic Plasticity. Neuropharmacology. 2024-06-14. PMID:38876308. |
through a comparative analysis across three main forebrain structures-the hippocampus, amygdala, and prefrontal cortex, this review discusses the actions of 5-ht on synaptic plasticity, offering insights into its role as a neuromodulator involved in emotional and cognitive functions. |
2024-06-14 |
2024-06-17 |
Not clear |
| Xi Yu, Jun Guo, Yueyang Song, Bin Wei, Yajun Shi, Yan Zhao, Zejun Zhao, Qinqin Gao, Bin Wang, Miao Su. HDAC1/2/3-mediated downregulation of neurogranin is involved in cognitive impairment in offspring exposed to maternal subclinical hypothyroidism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 12. 2024-06-12. PMID:38865202. |
chip analysis revealed that h3k9ac on the neurogranin (ng) promoter was reduced in the hippocampus of the offspring of sch, with a significant reduction in ng protein, leading to reduced expression levels of synaptic plasticity markers psd95 (a membrane-associated protein in the postsynaptic density) and syn (synaptophysin, a specific marker for presynaptic terminals), and impaired synaptic plasticity. |
2024-06-12 |
2024-06-15 |
mouse |
| Hardy Hagena, Denise Manahan-Vaugha. Interplay of hippocampal long-term potentiation and long-term depression in enabling memory representations. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 379. issue 1906. 2024-06-10. PMID:38853558. |
hippocampal long-term potentiation (ltp) and long-term depression (ltd) are hebbian forms of synaptic plasticity that are widely believed to comprise the physiological correlates of associative learning. |
2024-06-10 |
2024-06-14 |
Not clear |
| Kuldeep Tripathi, Somoday Hazra, Joyeeta Dutta Hazra, Silvia Mandel, Ruchi Anunu, Martin Kriebel, Hansjurgen Volkmer, Gal Richter-Levi. Selective knockdown of GABAA-α2 subunit in the dorsal dentate gyrus in adulthood induces anxiety, learning and memory deficits and impairs synaptic plasticity. The European journal of neuroscience. 2024-06-10. PMID:38858171. |
given the high expression of gabaa α2 in the dentate gyrus (dg) sub-field of the hippocampus, we sought to examine whether manipulation of the α2 subunit in this area will evoke changes in emotional behaviour, memory and learning as well as in synaptic plasticity. |
2024-06-10 |
2024-06-14 |
rat |
| Yan Sun, Hailou Zhang, Ruiyi Liu, Yanqing Wang, Xiangrui Zhang, Rumin Huang, Boran Zhu, Haoxin W. Zexieyin formula alleviates Alzheimer's disease via post-synaptic CaMKII modulating AMPA receptor: Involved in promoting neurogenesis to strengthen synaptic plasticity in mice hippocampus. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 131. 2024-06-09. PMID:38852473. |
zexieyin formula alleviates alzheimer's disease via post-synaptic camkii modulating ampa receptor: involved in promoting neurogenesis to strengthen synaptic plasticity in mice hippocampus. |
2024-06-09 |
2024-06-14 |
mouse |
| Ana Belén Sanz-Martos, María Roca, Mariano Ruiz-Gayo, Nuria Del Olm. TRIBUTYRIN REVERSES THE DELETERIOUS EFFECT OF SATURATED FAT ON WORKING MEMORY AND SYNAPTIC PLASTICITY IN JUVENILE MICE: DIFFERENTIAL EFFECTS IN MALES AND FEMALES. European journal of pharmacology. 2024-06-09. PMID:38852700. |
our research group has shown that tributyrin (tb), a butyric acid prodrug, reverses deficits in spatial memory and modulates hippocampal synaptic plasticity. |
2024-06-09 |
2024-06-14 |
mouse |
| Ana Belén Sanz-Martos, María Roca, Mariano Ruiz-Gayo, Nuria Del Olm. TRIBUTYRIN REVERSES THE DELETERIOUS EFFECT OF SATURATED FAT ON WORKING MEMORY AND SYNAPTIC PLASTICITY IN JUVENILE MICE: DIFFERENTIAL EFFECTS IN MALES AND FEMALES. European journal of pharmacology. 2024-06-09. PMID:38852700. |
hippocampal expression of genes involved in glutamatergic transmission as well as synaptic plasticity (long-term potentiation -ltp- and long-term depression -ltd-) were also analyzed. |
2024-06-09 |
2024-06-14 |
mouse |
| Gabriel Reichert Blume, Luiz Fernando Freire Roye. Peripheral to brain and hippocampus crosstalk induced by exercise mediates cognitive and structural hippocampal adaptations. Life sciences. 2024-06-09. PMID:38852798. |
both learning and memory as well as other hippocampal functional-related changes such as neurogenesis, cell proliferation, dendrite morphology and synaptic plasticity are controlled by these exercise responsive peripheral proteins. |
2024-06-09 |
2024-06-14 |
Not clear |