| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guillermo González-H, Itzel Jatziri Contreras-García, Karla Sánchez-Huerta, Claudio M T Queiroz, Luis Ricardo Gallardo Gudiño, Julieta G Mendoza-Torreblanca, Sergio R Zamudi. Levetiracetam Reduced the Basal Excitability of the Dentate Gyrus without Restoring Impaired Synaptic Plasticity in Rats with Temporal Lobe Epilepsy. Brain sciences. vol 10. issue 9. 2020-10-27. PMID:32933015. |
therefore, through the measurement of evoked field potentials, this study aimed to comprehensively identify the alterations in the excitability and the short-term (depression/facilitation) and long-term synaptic plasticity (long-term potentiation, ltp) of the dentate gyrus of the hippocampus in a lithium-pilocarpine rat model of tle, as well as their possible restoration by lev (1 week; 300 mg/kg/day). |
2020-10-27 |
2023-08-13 |
rat |
| Antonio de Iure, Petra Mazzocchetti, Guendalina Bastioli, Barbara Picconi, Cinzia Costa, Ivan Marchionni, Giorgio Casari, Alessandro Tozzi, Daniela Pietrobon, Paolo Calabres. Differential effect of FHM2 mutation on synaptic plasticity in distinct hippocampal regions. Cephalalgia : an international journal of headache. vol 39. issue 10. 2020-10-26. PMID:30922082. |
differential effect of fhm2 mutation on synaptic plasticity in distinct hippocampal regions. |
2020-10-26 |
2023-08-13 |
Not clear |
| Tala Khazen, Ossama A Hatoum, Guillaume Ferreira, Mouna Marou. Acute exposure to a high-fat diet in juvenile male rats disrupts hippocampal-dependent memory and plasticity through glucocorticoids. Scientific reports. vol 9. issue 1. 2020-10-20. PMID:31439894. |
juvenile hfd abolished both hippocampal synaptic plasticity, assessed through in vivo long-term potentiation (ltp) in ca1, and long-term hippocampal-dependent memory, using object location memory (olm). |
2020-10-20 |
2023-08-13 |
rat |
| Xialin Sun, Tingwen Zhang, Yan Zhao, Enbo Cai, Hongyan Zhu, Shuangli Li. Panaxynol attenuates CUMS-induced anxiety and depressive-like behaviors via regulating neurotransmitters, synapses and the HPA axis in mice. Food & function. vol 11. issue 2. 2020-10-19. PMID:32048672. |
meanwhile, pal promotes the release of 5-ht and da in the hippocampus and improves synaptic plasticity in the hippocampus, allowing neurotransmitters to function more effectively. |
2020-10-19 |
2023-08-13 |
mouse |
| Yingrak Boondam, Phanit Songvut, Mayuree H Tantisira, Sompol Tapechum, Kanokwan Tilokskulchai, Narawut Pakapro. Inverted U-shaped response of a standardized extract of Centella asiatica (ECa 233) on memory enhancement. Scientific reports. vol 9. issue 1. 2020-10-14. PMID:31182820. |
we used the morris water maze to test spatial learning and performed acute brain slice recording to measure changes of synaptic plasticity in the hippocampus, a core brain region for memory formation. |
2020-10-14 |
2023-08-13 |
rat |
| Yingrak Boondam, Phanit Songvut, Mayuree H Tantisira, Sompol Tapechum, Kanokwan Tilokskulchai, Narawut Pakapro. Inverted U-shaped response of a standardized extract of Centella asiatica (ECa 233) on memory enhancement. Scientific reports. vol 9. issue 1. 2020-10-14. PMID:31182820. |
there was an inverted u-shaped response of eca 233 on memory enhancement; 30 mg/kg maximally enhanced memory retention with an increase of synaptic plasticity and plasticity-related proteins in hippocampus. |
2020-10-14 |
2023-08-13 |
rat |
| Yao Wang, Yu-Zhang Liu, Lidan Wang, Wei Tang, Zhiru Wan. Silent Synapse Unsilencing in Hippocampal CA1 Neurons for Associative Fear Memory Storage. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30462151. |
clarifying learning-induced synaptic plasticity in hippocampal circuits is critical for understanding hippocampal mechanisms of memory acquisition and storage. |
2020-10-13 |
2023-08-13 |
mouse |
| Yao Wang, Yu-Zhang Liu, Lidan Wang, Wei Tang, Zhiru Wan. Silent Synapse Unsilencing in Hippocampal CA1 Neurons for Associative Fear Memory Storage. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30462151. |
however, as a neural basis of memory encoding, the nature of synaptic plasticity underlying hippocampal neuronal responses to memorized stimulation remains elusive. |
2020-10-13 |
2023-08-13 |
mouse |
| Emilce Artur de la Villarmois, Laura A Gabach, Santiago Bianconi, Maria Belen Poretti, Victoria Occhieppo, Helgi B Schiöth, Valeria P Carlini, Mariela Fernanda Pére. Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31378002. |
particularly, cocaine sensitization in rats enhanced synaptic plasticity within the hippocampus, an important brain region for the associative learning processes underlying drug addiction. |
2020-10-07 |
2023-08-13 |
rat |
| Emilce Artur de la Villarmois, Laura A Gabach, Santiago Bianconi, Maria Belen Poretti, Victoria Occhieppo, Helgi B Schiöth, Valeria P Carlini, Mariela Fernanda Pére. Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31378002. |
nitric oxide (no) is a neurotransmitter involved in both, hippocampal synaptic plasticity and cocaine sensitization. |
2020-10-07 |
2023-08-13 |
rat |
| Emilce Artur de la Villarmois, Laura A Gabach, Santiago Bianconi, Maria Belen Poretti, Victoria Occhieppo, Helgi B Schiöth, Valeria P Carlini, Mariela Fernanda Pére. Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31378002. |
it has been previously demonstrated a key role of nos-1/no/sgc/cgmp signaling pathway in the development of cocaine sensitization and in the associated enhancement of hippocampal synaptic plasticity. |
2020-10-07 |
2023-08-13 |
rat |
| Emilce Artur de la Villarmois, Laura A Gabach, Santiago Bianconi, Maria Belen Poretti, Victoria Occhieppo, Helgi B Schiöth, Valeria P Carlini, Mariela Fernanda Pére. Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31378002. |
nos-1 inhibition after sensitization reversed behavioral expression and the highest level of hippocampal synaptic plasticity. |
2020-10-07 |
2023-08-13 |
rat |
| Jessica L Huebschman, Kitzia S Corona, Yuhong Guo, Laura N Smit. The Fragile X Mental Retardation Protein Regulates Striatal Medium Spiny Neuron Synapse Density and Dendritic Spine Morphology. Frontiers in molecular neuroscience. vol 13. 2020-10-06. PMID:33013316. |
loss of fmrp, as in fragile x syndrome (fxs), is a leading monogenic cause of autism and results in altered structural and functional synaptic plasticity, widely described in the hippocampus and cortex. |
2020-10-06 |
2023-08-13 |
Not clear |
| Trina Basu, Kenneth J O'Riordan, Barry A Schoenike, Nadia N Khan, Eli P Wallace, Genesis Rodriguez, Rama K Maganti, Avtar Roopr. Histone deacetylase inhibitors restore normal hippocampal synaptic plasticity and seizure threshold in a mouse model of Tuberous Sclerosis Complex. Scientific reports. vol 9. issue 1. 2020-10-05. PMID:30918308. |
histone deacetylase inhibitors restore normal hippocampal synaptic plasticity and seizure threshold in a mouse model of tuberous sclerosis complex. |
2020-10-05 |
2023-08-13 |
mouse |
| Alexi Nott, Sukhee Cho, Jinsoo Seo, Li-Huei Tsa. HDAC2 expression in parvalbumin interneurons regulates synaptic plasticity in the mouse visual cortex. Neuroepigenetics. vol 1. 2020-10-01. PMID:25705589. |
the transcription regulator, histone deacetylase 2 (hdac2), has been shown to modulate synaptic plasticity and learning processes in hippocampal excitatory neurons. |
2020-10-01 |
2023-08-13 |
mouse |
| Emily E Noble, Scott E Kanosk. Early life exposure to obesogenic diets and learning and memory dysfunction. Current opinion in behavioral sciences. vol 9. 2020-10-01. PMID:26858972. |
various neurobiological mechanisms have been identified that may link early life consumption of obesogenic dietary factors with hippocampal dysfunction, including increased neuroinflammation and reduced neurotrophin mediated regulation of neurogenesis and synaptic plasticity. |
2020-10-01 |
2023-08-13 |
Not clear |
| Hardy Hagena, Denise Manahan-Vaugha. Dopamine D1/D5, But not D2/D3, Receptor Dependency of Synaptic Plasticity at Hippocampal Mossy Fiber Synapses that Is Enabled by Patterned Afferent Stimulation, or Spatial Learning. Frontiers in synaptic neuroscience. vol 8. 2020-10-01. PMID:27721791. |
dopamine d1/d5, but not d2/d3, receptor dependency of synaptic plasticity at hippocampal mossy fiber synapses that is enabled by patterned afferent stimulation, or spatial learning. |
2020-10-01 |
2023-08-13 |
rat |
| Hannah Twarkowski, Denise Manahan-Vaugha. Loss of Catecholaminergic Neuromodulation of Persistent Forms of Hippocampal Synaptic Plasticity with Increasing Age. Frontiers in synaptic neuroscience. vol 8. 2020-10-01. PMID:27725799. |
loss of catecholaminergic neuromodulation of persistent forms of hippocampal synaptic plasticity with increasing age. |
2020-10-01 |
2023-08-13 |
rat |
| Hannah Twarkowski, Denise Manahan-Vaugha. Loss of Catecholaminergic Neuromodulation of Persistent Forms of Hippocampal Synaptic Plasticity with Increasing Age. Frontiers in synaptic neuroscience. vol 8. 2020-10-01. PMID:27725799. |
neuromodulation by means of the catecholaminergic system is a key component of motivation-driven learning and behaviorally modulated hippocampal synaptic plasticity. |
2020-10-01 |
2023-08-13 |
rat |
| Hannah Twarkowski, Denise Manahan-Vaugha. Loss of Catecholaminergic Neuromodulation of Persistent Forms of Hippocampal Synaptic Plasticity with Increasing Age. Frontiers in synaptic neuroscience. vol 8. 2020-10-01. PMID:27725799. |
in particular, dopamine acting on d1/d5 receptors and noradrenaline acting on beta-adrenergic receptors exert a very potent regulation of forms of hippocampal synaptic plasticity that last for very long-periods of time (>24 h), and occur in conjunction with novel spatial learning. |
2020-10-01 |
2023-08-13 |
rat |