Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jade G Quirion, Matthew P Parson. The Onset and Progression of Hippocampal Synaptic Plasticity Deficits in the Q175FDN Mouse Model of Huntington Disease. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31379510. |
the onset and progression of hippocampal synaptic plasticity deficits in the q175fdn mouse model of huntington disease. |
2020-10-01 |
2023-08-13 |
mouse |
Jade G Quirion, Matthew P Parson. The Onset and Progression of Hippocampal Synaptic Plasticity Deficits in the Q175FDN Mouse Model of Huntington Disease. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31379510. |
deficits in synaptic plasticity, including hippocampal long-term potentiation (ltp), have been identified in various mouse models of hd and are thought to contribute to the debilitating cognitive symptoms associated with the disease. |
2020-10-01 |
2023-08-13 |
mouse |
Jade G Quirion, Matthew P Parson. The Onset and Progression of Hippocampal Synaptic Plasticity Deficits in the Q175FDN Mouse Model of Huntington Disease. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31379510. |
to the best of our knowledge, the present study represents the most thorough characterization to date of the onset and progression of hippocampal synaptic plasticity deficits in a mouse model of hd, and should prove valuable to future studies exploring cellular mechanisms underlying the debilitating cognitive decline in hd. |
2020-10-01 |
2023-08-13 |
mouse |
Matteo Spinelli, Salvatore Fusco, Claudio Grass. Brain Insulin Resistance and Hippocampal Plasticity: Mechanisms and Biomarkers of Cognitive Decline. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31417349. |
here, we summarize the molecular evidence linking alteration of hippocampal insulin sensitivity with changes of both adult neurogenesis and synaptic plasticity. |
2020-10-01 |
2023-08-13 |
Not clear |
Lucia Ciranna, Lara Cost. Pituitary Adenylate Cyclase-Activating Polypeptide Modulates Hippocampal Synaptic Transmission and Plasticity: New Therapeutic Suggestions for Fragile X Syndrome. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31827422. |
in this context, results from our laboratory demonstrate that pacap rescued metabotropic glutamate receptor-mediated synaptic plasticity in the hippocampus of a mouse model of fragile x syndrome (fxs), a genetic form of intellectual disability. |
2020-10-01 |
2023-08-13 |
mouse |
Alessandro Tozzi, Valentina Durante, Paolo Manca, Michela Di Mauro, Juan Blasi, Silvarosa Grassi, Paolo Calabresi, Suguru Kawato, Vito Enrico Pettoross. Bidirectional Synaptic Plasticity Is Driven by Sex Neurosteroids Targeting Estrogen and Androgen Receptors in Hippocampal CA1 Pyramidal Neurons. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31866827. |
neuroactive estrogenic and androgenic steroids influence synaptic transmission, finely modulating synaptic plasticity in several brain regions including the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
Sabine Grosser, Nadine Buck, Karl-Heinz Braunewell, Kate E Gilling, Christian Wozny, Pawel Fidzinski, Joachim Beh. Loss of Long-Term Potentiation at Hippocampal Output Synapses in Experimental Temporal Lobe Epilepsy. Frontiers in molecular neuroscience. vol 13. 2020-10-01. PMID:32982687. |
in the present study, we investigate changes of synaptic plasticity at hippocampal output structures in an experimental animal model of tle. |
2020-10-01 |
2023-08-13 |
rat |
Sabine Grosser, Nadine Buck, Karl-Heinz Braunewell, Kate E Gilling, Christian Wozny, Pawel Fidzinski, Joachim Beh. Loss of Long-Term Potentiation at Hippocampal Output Synapses in Experimental Temporal Lobe Epilepsy. Frontiers in molecular neuroscience. vol 13. 2020-10-01. PMID:32982687. |
our findings suggest that in tle, disturbances of synaptic plasticity may influence the information flow between the hippocampus and the neocortex. |
2020-10-01 |
2023-08-13 |
rat |
Sayyed Alireza Talaei, Abolfazl Azami, Mahmoud Salam. Developmental effect of light deprivation on synaptic plasticity of rats' hippocampus: implications for melatonin. Iranian journal of basic medical sciences. vol 19. issue 8. 2020-09-30. PMID:27746873. |
developmental effect of light deprivation on synaptic plasticity of rats' hippocampus: implications for melatonin. |
2020-09-30 |
2023-08-13 |
rat |
Sayyed Alireza Talaei, Abolfazl Azami, Mahmoud Salam. Developmental effect of light deprivation on synaptic plasticity of rats' hippocampus: implications for melatonin. Iranian journal of basic medical sciences. vol 19. issue 8. 2020-09-30. PMID:27746873. |
this study aimed to investigate developmental effect of exogenous melatonin on synaptic plasticity of hippocampus of light deprived rats. |
2020-09-30 |
2023-08-13 |
rat |
Cai-Xia Zheng, Min Lu, Ya-Bi Guo, Feng-Xia Zhang, Hua Liu, Feng Guo, Xiao-Lin Huang, Xiao-Hua Ha. Electroacupuncture Ameliorates Learning and Memory and Improves Synaptic Plasticity via Activation of the PKA/CREB Signaling Pathway in Cerebral Hypoperfusion. Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2020-09-30. PMID:27829866. |
these results demonstrated that ea could ameliorate learning and memory deficits and alleviate hippocampal synaptic plasticity impairment of cerebral hypoperfusion rats, potentially mediated by pka/creb signaling pathway. |
2020-09-30 |
2023-08-13 |
rat |
Tao Han, Yanyu Qin, Chenzhi Mou, Min Wang, Meng Jiang, Bin Li. Seizure induced synaptic plasticity alteration in hippocampus is mediated by IL-1β receptor through PI3K/Akt pathway. American journal of translational research. vol 8. issue 10. 2020-09-30. PMID:27830035. |
seizure induced synaptic plasticity alteration in hippocampus is mediated by il-1β receptor through pi3k/akt pathway. |
2020-09-30 |
2023-08-13 |
mouse |
Tao Han, Yanyu Qin, Chenzhi Mou, Min Wang, Meng Jiang, Bin Li. Seizure induced synaptic plasticity alteration in hippocampus is mediated by IL-1β receptor through PI3K/Akt pathway. American journal of translational research. vol 8. issue 10. 2020-09-30. PMID:27830035. |
it is concluded that the il-1β induced by ptz-induced seizures may impair the synaptic plasticity alteration in hippocampus as well as learning and memory ability by pi3k/akt signaling pathway. |
2020-09-30 |
2023-08-13 |
mouse |
Dong Sup Hwang, Hyo Bum Kwak, Il Gyu Ko, Sung Eun Kim, Jun Jang Jin, Eun Sang Ji, Hyun Hee Choi, Oh Young Kwo. Treadmill Exercise Improves Memory Function Depending on Circadian Rhythm Changes in Mice. International neurourology journal. vol 20. issue Suppl 2. 2020-09-30. PMID:27915477. |
exercise enhances memory function by increasing neurogenesis in the hippocampus, and circadian rhythms modulate synaptic plasticity in the hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |
Rodrigo F Torres, Cecilia Hidalgo, Bredford Ker. Mecp2 Mediates Experience-Dependent Transcriptional Upregulation of Ryanodine Receptor Type-3. Frontiers in molecular neuroscience. vol 10. 2020-09-30. PMID:28659760. |
ryanodine receptors are intracellular calcium channels that contribute to hippocampal synaptic plasticity, dendritic spine remodeling, and participate in learning and memory processes. |
2020-09-30 |
2023-08-13 |
mouse |
Mingyang Deng, Han Xiao, Hainan Zhang, Hongling Peng, Huan Yuan, Yunxiao Xu, Guangsen Zhang, Zhiping H. Mesenchymal Stem Cell-Derived Extracellular Vesicles Ameliorates Hippocampal Synaptic Impairment after Transient Global Ischemia. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28769765. |
we examined the consequence of transient global ischemia on pre- and post-synaptic functions of the hippocampal ca3-ca1 synapses at basal level, and long-term potentiation (ltp), an activity-dependent form of synaptic plasticity. |
2020-09-30 |
2023-08-13 |
mouse |
Mohammad Hassan Heidari, Abdollah Amini, Zohreh Bahrami, Ali Shahriari, Abolfazl Movafagh, Reihane Heidar. Corrigendum to "Effect of Chronic Morphine Consumption on Synaptic Plasticity of Rat's Hippocampus: A Transmission Electron Microscopy Study". Neurology research international. vol 2017. 2020-09-30. PMID:28831311. |
corrigendum to "effect of chronic morphine consumption on synaptic plasticity of rat's hippocampus: a transmission electron microscopy study". |
2020-09-30 |
2023-08-13 |
rat |
Ruhui Lin, Xiaojie Li, Weilin Liu, Wenlie Chen, Kunqiang Yu, Congkuai Zhao, Jia Huang, Shanli Yang, Hongwei Peng, Jing Tao, Lidian Che. Electro-acupuncture ameliorates cognitive impairment via improvement of brain-derived neurotropic factor-mediated hippocampal synaptic plasticity in cerebral ischemia-reperfusion injured rats. Experimental and therapeutic medicine. vol 14. issue 3. 2020-09-30. PMID:28962170. |
electro-acupuncture ameliorates cognitive impairment via improvement of brain-derived neurotropic factor-mediated hippocampal synaptic plasticity in cerebral ischemia-reperfusion injured rats. |
2020-09-30 |
2023-08-13 |
rat |
Ruhui Lin, Xiaojie Li, Weilin Liu, Wenlie Chen, Kunqiang Yu, Congkuai Zhao, Jia Huang, Shanli Yang, Hongwei Peng, Jing Tao, Lidian Che. Electro-acupuncture ameliorates cognitive impairment via improvement of brain-derived neurotropic factor-mediated hippocampal synaptic plasticity in cerebral ischemia-reperfusion injured rats. Experimental and therapeutic medicine. vol 14. issue 3. 2020-09-30. PMID:28962170. |
the present study investigated whether brain-derived neurotropic factor (bdnf) mediates hippocampal synaptic plasticity as the underlying mechanism. |
2020-09-30 |
2023-08-13 |
rat |
Ruhui Lin, Xiaojie Li, Weilin Liu, Wenlie Chen, Kunqiang Yu, Congkuai Zhao, Jia Huang, Shanli Yang, Hongwei Peng, Jing Tao, Lidian Che. Electro-acupuncture ameliorates cognitive impairment via improvement of brain-derived neurotropic factor-mediated hippocampal synaptic plasticity in cerebral ischemia-reperfusion injured rats. Experimental and therapeutic medicine. vol 14. issue 3. 2020-09-30. PMID:28962170. |
collectively, the findings suggested that bdnf-mediated hippocampal synaptic plasticity may be one mechanism via which ea treatment at the shenting (du24) and baihui (du20) acupoints improves cognitive function in cerebral i/r injured rats. |
2020-09-30 |
2023-08-13 |
rat |