| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julia C Bartsch, Joachim Beh. Noncanonical, Dopamine-Dependent Long-Term Potentiation at Hippocampal Output Synapses in a Rodent Model of First-Episode Psychosis. Frontiers in molecular neuroscience. vol 13. 2020-09-28. PMID:32317931. |
recently, subregion-specific aberrant and maladaptive hippocampal synaptic plasticity has been suggested as one of the mechanistic underpinnings. |
2020-09-28 |
2023-08-13 |
rat |
| Chao-Chao Yu, Jia Wang, Si-Si Ye, Shan Gao, Jia Li, Li Wang, Tao Jiang, Xue-Song Wang, Bo-Cun Li, Qing Shu, Wei Lu, Yan-Jun Du, Li-Hong Kon. Preventive Electroacupuncture Ameliorates D-Galactose-Induced Alzheimer's Disease-Like Pathology and Memory Deficits Probably via Inhibition of GSK3 Evidence-based complementary and alternative medicine : eCAM. vol 2020. 2020-09-28. PMID:32382276. |
we found that preventive electroacupuncture at gv20-bl23 acupoints during aging attenuated the hippocampal loss of dendritic spines, ameliorated neuronal microtubule injuries, and increased the expressions of postsynaptic psd95 and presynaptic syn, two important synapse-associated proteins involved in synaptic plasticity. |
2020-09-28 |
2023-08-13 |
rat |
| Joana Sa de Almeida, Mariana Vargas, João Fonseca-Gomes, Sara Ramalho Tanqueiro, Rita F Belo, Catarina Miranda-Lourenço, Ana M Sebastião, Maria José Diógenes, Teresa F Pai. Microglial Sirtuin 2 Shapes Long-Term Potentiation in Hippocampal Slices. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32625056. |
here we found that decreased levels of sirtuin 2 (sirt2) deacetylase in microglia affects hippocampal synaptic plasticity under inflammatory conditions. |
2020-09-28 |
2023-08-13 |
mouse |
| Jennifer Mayordomo-Cava, Guillermo Iborra-Lázaro, Souhail Djebari, Sara Temprano-Carazo, Irene Sánchez-Rodríguez, Danko Jeremic, Agnès Gruart, José María Delgado-García, Lydia Jiménez-Díaz, Juan D Navarro-Lópe. Impairments of Synaptic Plasticity Induction Threshold and Network Oscillatory Activity in the Hippocampus Underlie Memory Deficits in a Non-Transgenic Mouse Model of Amyloidosis. Biology. vol 9. issue 7. 2020-09-28. PMID:32698467. |
impairments of synaptic plasticity induction threshold and network oscillatory activity in the hippocampus underlie memory deficits in a non-transgenic mouse model of amyloidosis. |
2020-09-28 |
2023-08-13 |
mouse |
| Dongqing Xia, Cuiting Min, Yinhua Chen, Ru Ling, Mengying Chen, Xiaonan L. Repetitive Pain in Neonatal Male Rats Impairs Hippocampus-Dependent Fear Memory Later in Life. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32733201. |
we hypothesized that exposure to repetitive pain in early life triggered hippocampal synaptic plasticity and resulted in memory deficiency in prepubertal and adult rats. |
2020-09-28 |
2023-08-13 |
rat |
| Hui Shen, Lindsay Kenney, Sheryl S Smit. Increased Dendritic Branching of and Reduced δ-GABA Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32733208. |
the onset of puberty represents the end of a period of optimal learning when impairments in synaptic plasticity are observed in the ca1 hippocampus of female mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Yan-Bin Xiyang, Ruan Liu, Xu-Yang Wang, Shan Li, Ya Zhao, Bing-Tuan Lu, Zhi-Cheng Xiao, Lian-Feng Zhang, Ting-Hua Wang, Jie Zhan. COX5A Plays a Vital Role in Memory Impairment Associated With Brain Aging Frontiers in aging neuroscience. vol 12. 2020-09-28. PMID:32754029. |
newly established transgenic mice with systemic cox5a overexpression (51% increase) resulted in the improvement of spatial recognition memory and hippocampal synaptic plasticity, recovery of hippocampal ca1 dendrites, and activation of the bdnf/erk1/2 signaling pathway |
2020-09-28 |
2023-08-13 |
mouse |
| b' Irene Sol\\xc3\\xa9s-Tarr\\xc3\\xa9s, N\\xc3\\xbaria Cabezas-Llobet, David Vaudry, Xavier Xifr\\xc3\\xb. Protective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide and Vasoactive Intestinal Peptide Against Cognitive Decline in Neurodegenerative Diseases. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32765225.' |
cognitive impairment has been related to neuronal cell death and/or synaptic plasticity alteration in important brain regions, such as the cerebral cortex, substantia nigra, striatum, and hippocampus. |
2020-09-28 |
2023-08-13 |
Not clear |
| Endi Xia, Fengyan Xu, Changbin Hu, Jay Prakash Prasad Kumal, Xudong Tang, Dongsheng Mao, Yixuan Li, Di Wu, Rui Zhang, Shuliang Wu, Liang Su. Young Blood Rescues the Cognition of Alzheimer's Model Mice by Restoring the Hippocampal Cholinergic Circuit. Neuroscience. vol 417. 2020-09-24. PMID:31404586. |
in the current study, we showed that young blood serum delivered intravenously attenuated deficits in hippocampal-dependent learning and memory, alleviated hippocampal aβ plaque pathology, restored synapse formation and synaptic plasticity, repaired the hippocampal cholinergic circuit, and triggered several canonical neuroprotective mechanisms [including repressor element 1-silencing transcription factor (rest)/forkhead box protein o1 (foxo1) signaling] in aged ad model mice. |
2020-09-24 |
2023-08-13 |
mouse |
| Ziyi Wang, Yuying Lin, Weitang Liu, Ping Kuang, Wenwen Lao, Yonghua Ji, Hongyan Zh. Voltage-Gated Sodium Channels Are Involved in Cognitive Impairments in Parkinson's Disease- like Rats. Neuroscience. vol 418. 2020-09-24. PMID:31473280. |
the abnormal synaptic plasticity in the hippocampus is suggested to be associated with cognitive dysfunction in pd. |
2020-09-24 |
2023-08-13 |
rat |
| Ana Contreras, Eduardo Polín, Miguel Miguéns, Carmen Pérez-García, Vicente Pérez, Mariano Ruiz-Gayo, Lidia Morales, Nuria Del Olm. Intermittent-Excessive and Chronic-Moderate Ethanol Intake during Adolescence Impair Spatial Learning, Memory and Cognitive Flexibility in the Adulthood. Neuroscience. vol 418. 2020-09-24. PMID:31491502. |
hippocampal synaptic plasticity was assessed by measuring field excitatory postsynaptic potentials. |
2020-09-24 |
2023-08-13 |
rat |
| Ivana Brito, Luiz Roberto G Britto, Elenice Aparecida M Ferrar. Retrieval of contextual aversive memory and induction of Zenk expression in the hippocampus of pigeons. Brain research bulletin. vol 153. 2020-09-24. PMID:31586459. |
these data suggest that zenk-mediated processes of synaptic plasticity in the hippocampus are induced during the retrieval of conditioned fear memory in the pigeon. |
2020-09-24 |
2023-08-13 |
pigeon |
| Keiichi Kadoyama, Kenji Matsuura, Masaoki Takano, Koji Maekura, Yukari Inoue, Shogo Matsuyam. Changes in the expression of prefoldin subunit 5 depending on synaptic plasticity in the mouse hippocampus. Neuroscience letters. vol 712. 2020-09-23. PMID:31505240. |
changes in the expression of prefoldin subunit 5 depending on synaptic plasticity in the mouse hippocampus. |
2020-09-23 |
2023-08-13 |
mouse |
| Keiichi Kadoyama, Kenji Matsuura, Masaoki Takano, Koji Maekura, Yukari Inoue, Shogo Matsuyam. Changes in the expression of prefoldin subunit 5 depending on synaptic plasticity in the mouse hippocampus. Neuroscience letters. vol 712. 2020-09-23. PMID:31505240. |
nicotine application caused a long-term potentiation (ltp)-like facilitation in vivo, that is synaptic plasticity, in the mouse hippocampus. |
2020-09-23 |
2023-08-13 |
mouse |
| Keiichi Kadoyama, Kenji Matsuura, Masaoki Takano, Koji Maekura, Yukari Inoue, Shogo Matsuyam. Changes in the expression of prefoldin subunit 5 depending on synaptic plasticity in the mouse hippocampus. Neuroscience letters. vol 712. 2020-09-23. PMID:31505240. |
in transgenic mice overexpressing human tau with n279 k mutation as a model of alzheimer's disease that showed impaired synaptic plasticity, the levels of pfdn5 mrna and protein in the hippocampus were significantly decreased in an age-dependent manner as compared with age-matched control. |
2020-09-23 |
2023-08-13 |
mouse |
| Keiichi Kadoyama, Kenji Matsuura, Masaoki Takano, Koji Maekura, Yukari Inoue, Shogo Matsuyam. Changes in the expression of prefoldin subunit 5 depending on synaptic plasticity in the mouse hippocampus. Neuroscience letters. vol 712. 2020-09-23. PMID:31505240. |
the findings demonstrated that the level of pfdn5 protein in the hippocampus was changed depending on the situation of synaptic plasticity. |
2020-09-23 |
2023-08-13 |
mouse |
| Hadi Zarif, Agnès Paquet, Kevin Lebrigand, Marie-Jeanne Arguel, Catherine Heurteaux, Nicolas Glaichenhaus, Joëlle Chabry, Alice Guyon, Agnès Petit-Paite. CD4+ T Cells Affect the Thyroid Hormone Transport at the Choroid Plexus in Mice Raised in Enriched Environment. Neuroimmunomodulation. vol 26. issue 2. 2020-09-22. PMID:30703773. |
others and we have shown that t cells have an important role in hippocampal synaptic plasticity, including neurogenesis in the dentate gyrus, spinogenesis, and glutamatergic synaptic function in the ca of the hippocampus. |
2020-09-22 |
2023-08-13 |
mouse |
| Jianxing Lian, Kai Li, Jing Gao, Xiaoyue Tan, Zhuo Yan. Legumain acts on neuroinflammatory to affect CUS-induced cognitive impairment. Behavioural brain research. vol 376. 2020-09-22. PMID:31509774. |
in conclusion, our results suggested that legumain may be an effective therapeutic target for cognitive impairment as was seen within the cus model and legumain ko reduced the level of neuroinflammation, thereby improving the hippocampal synaptic plasticity and cognitive impairment of stressed mice. |
2020-09-22 |
2023-08-13 |
mouse |
| James E Orfila, Robert M Dietz, Krista M Rodgers, Andra Dingman, Olivia P Patsos, Ivelisse Cruz-Torres, Himmat Grewal, Frank Strnad, Christian Schroeder, Paco S Herso. Experimental pediatric stroke shows age-specific recovery of cognition and role of hippocampal Nogo-A receptor signaling. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 40. issue 3. 2020-09-21. PMID:30762478. |
juvenile and adult mice subjected to 45-min mcao, and extracellular field recordings of ca1 neurons were performed to assess hippocampal synaptic plasticity changes after mcao, and contextual fear conditioning was performed to evaluate memory and biochemistry used to analyze nogo-a expression. |
2020-09-21 |
2023-08-13 |
mouse |
| Anna Yu-Szu Huang, Junsung Woo, Debosmita Sardar, Brittney Lozzi, Navish A Bosquez Huerta, Chia-Ching John Lin, Daniela Felice, Antrix Jain, Adriana Paulucci-Holthauzen, Benjamin Denee. Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities. Neuron. vol 106. issue 6. 2020-09-21. PMID:32320644. |
these changes in hippocampal astrocytes did not affect basal neuronal properties but specifically inhibited synaptic plasticity, which is regulated by nfia in astrocytes through calcium-dependent mechanisms. |
2020-09-21 |
2023-08-13 |
Not clear |