| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David J Titus, Timothy Johnstone, Nathan H Johnson, Sidney H London, Meghana Chapalamadugu, Derk Hogenkamp, Kelvin W Gee, Coleen M Atkin. Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury. PloS one. vol 14. issue 10. 2020-03-11. PMID:31581202. |
our results demonstrate that avl-3288 improves hippocampal synaptic plasticity, and learning and memory performance after tbi in the chronic recovery period. |
2020-03-11 |
2023-08-13 |
human |
| Mohammad Shabani, Fariba Ebrahimpoor, Maryam Arab Firouzjaei, Leila Kamali, Seyed Mostafa Shid Moosavi, Ali Noorafshan, Masoud Haghan. Modulation of sphingosine-1-phosphate receptor by FTY720 contributes in improvement of hepatic encephalopathy induced by bile duct ligation. Brain research bulletin. vol 146. 2020-03-10. PMID:30660717. |
the bdl led to considerable loss of hippocampal neurons and apoptosis, along with large impairments in their intrinsic electrophysiological properties, including decrease of firing frequency and increases of first spike latency (fsl), ahp amplitude, irregularity of firing, and half-width, as well as impaired long-term synaptic plasticity and memory. |
2020-03-10 |
2023-08-13 |
Not clear |
| Mei Li, Mingdan You, Siyao Li, Zhenmin Qiu, Yi Wan. Effects of maternal exposure to nonylphenol on learning and memory in offspring involve inhibition of BDNF-PI3K/Akt signaling. Brain research bulletin. vol 146. 2020-03-10. PMID:30660719. |
we also investigated the activation of bdnf-pi3k/akt signaling and the expression of its target protein psd-95 in offspring hippocampus, which are curial for the synaptic plasticity and learning and memory. |
2020-03-10 |
2023-08-13 |
Not clear |
| Maja Djurisic, Barbara K Brott, Nay L Saw, Mehrdad Shamloo, Carla J Shat. Activity-dependent modulation of hippocampal synaptic plasticity via PirB and endocannabinoids. Molecular psychiatry. vol 24. issue 8. 2020-03-09. PMID:29670176. |
activity-dependent modulation of hippocampal synaptic plasticity via pirb and endocannabinoids. |
2020-03-09 |
2023-08-13 |
mouse |
| Maofang Hei, Peng Chen, Shuzhong Wang, Xuzhao Li, Mingrui Xu, Xiaoyan Zhu, Yi Wang, Jinyou Duan, Yong Huang, Shanting Zha. Effects of chronic mild stress induced depression on synaptic plasticity in mouse hippocampus. Behavioural brain research. vol 365. 2020-03-09. PMID:30825464. |
effects of chronic mild stress induced depression on synaptic plasticity in mouse hippocampus. |
2020-03-09 |
2023-08-13 |
mouse |
| Maofang Hei, Peng Chen, Shuzhong Wang, Xuzhao Li, Mingrui Xu, Xiaoyan Zhu, Yi Wang, Jinyou Duan, Yong Huang, Shanting Zha. Effects of chronic mild stress induced depression on synaptic plasticity in mouse hippocampus. Behavioural brain research. vol 365. 2020-03-09. PMID:30825464. |
strong evidence proved the important role of hippocampal synaptic plasticity in the mechanism of depression. |
2020-03-09 |
2023-08-13 |
mouse |
| Maofang Hei, Peng Chen, Shuzhong Wang, Xuzhao Li, Mingrui Xu, Xiaoyan Zhu, Yi Wang, Jinyou Duan, Yong Huang, Shanting Zha. Effects of chronic mild stress induced depression on synaptic plasticity in mouse hippocampus. Behavioural brain research. vol 365. 2020-03-09. PMID:30825464. |
this study investigated the effect of cms on synaptic plasticity in hippocampus. |
2020-03-09 |
2023-08-13 |
mouse |
| S Khoshghadam, F Sheikhzadeh Hesari, N Ahmadiasl, A Dastranj Tabrizi, S S Hosseinzadeh, A Ramou. The effect of exercise on reelin level in the hippocampus of diabetic rats. Bratislavske lekarske listy. vol 121. issue 2. 2020-03-09. PMID:32115961. |
diabetes is one of the most common diseases which can attenuate brain function by destroying hippocampus neurons, while reelin is a largely secreted extracellular matrix glycoprotein in the hippocampus causing synaptic plasticity, promoting postsynaptic structures and maturing neurons. |
2020-03-09 |
2023-08-13 |
rat |
| Ann M Laszczyk, Dailey Nettles, Tate A Pollock, Stephanie Fox, Melissa L Garcia, Jing Wang, L Darryl Quarles, Gwendalyn D Kin. FGF-23 Deficiency Impairs Hippocampal-Dependent Cognitive Function. eNeuro. vol 6. issue 2. 2020-03-05. PMID:30911673. |
however, fgf-23-deficient brains had no gross structural or developmental defects, no change in hippocampal synaptic plasticity, and only minor impairment to postnatal hippocampal neurogenesis. |
2020-03-05 |
2023-08-13 |
mouse |
| Sara Peñasco, Irantzu Rico-Barrio, Nagore Puente, Sonia María Gómez-Urquijo, Christine J Fontaine, Jon Egaña-Huguet, Svein Achicallende, Almudena Ramos, Leire Reguero, Izaskun Elezgarai, Patrick C Nahirney, Brian R Christie, Pedro Grande. Endocannabinoid long-term depression revealed at medial perforant path excitatory synapses in the dentate gyrus. Neuropharmacology. vol 153. 2020-03-03. PMID:31022405. |
the endocannabinoid system modulates synaptic plasticity in the hippocampus, but a link between long-term synaptic plasticity and the type 1 cannabinoid (cb |
2020-03-03 |
2023-08-13 |
Not clear |
| Zhen Tang, Shaowu Cheng, Yanyan Sun, Yunqiao Zhang, Xiying Xiang, Zhicui Ouyang, Xing Zhu, Bo Wang, Mingyan He. Early TLR4 inhibition reduces hippocampal injury at puberty in a rat model of neonatal hypoxic-ischemic brain damage via regulation of neuroimmunity and synaptic plasticity. Experimental neurology. vol 321. 2020-02-28. PMID:31442443. |
early tlr4 inhibition reduces hippocampal injury at puberty in a rat model of neonatal hypoxic-ischemic brain damage via regulation of neuroimmunity and synaptic plasticity. |
2020-02-28 |
2023-08-13 |
rat |
| Eric de Hoog, Mark K Lukewich, Gaynor E Spence. Retinoid receptor-based signaling plays a role in voltage-dependent inhibition of invertebrate voltage-gated Ca The Journal of biological chemistry. vol 294. issue 26. 2020-02-27. PMID:31048374. |
both rar and rxr signaling events are implicated in hippocampal synaptic plasticity. |
2020-02-27 |
2023-08-13 |
Not clear |
| Nathalie Pierrot, Laurence Ris, Ilie-Cosmin Stancu, Anna Doshina, Floriane Ribeiro, Donatienne Tyteca, Eric Baugé, Fanny Lalloyer, Liza Malong, Olivier Schakman, Karelle Leroy, Pascal Kienlen-Campard, Philippe Gailly, Jean-Pierre Brion, Ilse Dewachter, Bart Staels, Jean-Noël Octav. Sex-regulated gene dosage effect of PPARα on synaptic plasticity. Life science alliance. vol 2. issue 2. 2020-02-26. PMID:30894406. |
we report that pparα mediates the improvement of hippocampal synaptic plasticity upon rxr activation in a transgenic mouse model with cognitive deficits. |
2020-02-26 |
2023-08-13 |
mouse |
| Nathalie Pierrot, Laurence Ris, Ilie-Cosmin Stancu, Anna Doshina, Floriane Ribeiro, Donatienne Tyteca, Eric Baugé, Fanny Lalloyer, Liza Malong, Olivier Schakman, Karelle Leroy, Pascal Kienlen-Campard, Philippe Gailly, Jean-Pierre Brion, Ilse Dewachter, Bart Staels, Jean-Noël Octav. Sex-regulated gene dosage effect of PPARα on synaptic plasticity. Life science alliance. vol 2. issue 2. 2020-02-26. PMID:30894406. |
moreover, pparα knockdown in the hippocampus of cognition-impaired mice compromises the beneficial effects of rxr activation on synaptic plasticity only in males. |
2020-02-26 |
2023-08-13 |
mouse |
| Nathalie Pierrot, Laurence Ris, Ilie-Cosmin Stancu, Anna Doshina, Floriane Ribeiro, Donatienne Tyteca, Eric Baugé, Fanny Lalloyer, Liza Malong, Olivier Schakman, Karelle Leroy, Pascal Kienlen-Campard, Philippe Gailly, Jean-Pierre Brion, Ilse Dewachter, Bart Staels, Jean-Noël Octav. Sex-regulated gene dosage effect of PPARα on synaptic plasticity. Life science alliance. vol 2. issue 2. 2020-02-26. PMID:30894406. |
we conclude that striking sex differences in hippocampal synaptic plasticity are observed in mice, related to differences in pparα expression levels. |
2020-02-26 |
2023-08-13 |
mouse |
| Mélissa Glatigny, Stéphanie Moriceau, Manon Rivagorda, Mariana Ramos-Brossier, Anna C Nascimbeni, Fabien Lante, Mary R Shanley, Nadir Boudarene, Audrey Rousseaud, Allyson K Friedman, Carmine Settembre, Nicolas Kuperwasser, Gérard Friedlander, Alain Buisson, Etienne Morel, Patrice Codogno, Franck Our. Autophagy Is Required for Memory Formation and Reverses Age-Related Memory Decline. Current biology : CB. vol 29. issue 3. 2020-02-25. PMID:30661803. |
using hippocampal injections of genetic and pharmacological modulators of autophagy, we find that inducing autophagy in hippocampal neurons is required to form novel memory by promoting activity-dependent structural and functional synaptic plasticity, including dendritic spine formation, neuronal facilitation, and long-term potentiation. |
2020-02-25 |
2023-08-13 |
mouse |
| Nadia Yanet Cortés-Álvarez, César Rubén Vuelvas-Olmos, María Fernanda Pinto-González, Jorge Guzmán-Muñiz, Oscar Gonzalez-Perez, Norma Angélica Moy-Lópe. A high-fat diet during pregnancy impairs memory acquisition and increases leptin receptor expression in the hippocampus of rat offspring. Nutritional neuroscience. 2020-02-20. PMID:32075550. |
the hippocampus has high levels of leptin receptors (ob-r) that participate in synaptic plasticity. |
2020-02-20 |
2023-08-13 |
rat |
| Ulrika Wilhelmsson, Andrea Pozo-Rodrigalvarez, Marie Kalm, Yolanda de Pablo, Åsa Widestrand, Marcela Pekna, Milos Pekn. The role of GFAP and vimentin in learning and memory. Biological chemistry. vol 400. issue 9. 2020-02-17. PMID:31063456. |
mice deficient for gfap and vimentin (gfap-/-vim-/-) exhibit increased post-traumatic synaptic plasticity and increased basal and post-traumatic hippocampal neurogenesis. |
2020-02-17 |
2023-08-13 |
mouse |
| Fen Xue, Shan-Shan Xue, Ling Liu, Han-Fei Sang, Quan-Rui Ma, Qing-Rong Tan, Hua-Ning Wang, Cui-Hong Zhou, Zheng-Wu Pen. Early intervention with electroacupuncture prevents PTSD-like behaviors in rats through enhancing hippocampal endocannabinoid signaling. Progress in neuro-psychopharmacology & biological psychiatry. vol 93. 2020-02-14. PMID:30946940. |
the results showed that early ea intervention improved hippocampal synaptic plasticity and ameliorated ptsd-like behaviors and also increased expression of bdnf, daglα and cb1r. |
2020-02-14 |
2023-08-13 |
rat |
| Stefano Sartini, Davide Lattanzi, Michael Di Palma, David Savelli, Silvia Eusebi, Piero Sestili, Riccardo Cuppini, Patrizia Ambrogin. Maternal Creatine Supplementation Positively Affects Male Rat Hippocampal Synaptic Plasticity in Adult Offspring. Nutrients. vol 11. issue 9. 2020-02-10. PMID:31461895. |
maternal creatine supplementation positively affects male rat hippocampal synaptic plasticity in adult offspring. |
2020-02-10 |
2023-08-13 |
rat |