| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hamidreza Komaki, Nafiseh Faraji, Alireza Komaki, Siamak Shahidi, Farshid Etaee, Safoura Raoufi, Fatemeh Mirzae. Investigation of protective effects of coenzyme Q10 on impaired synaptic plasticity in a male rat model of Alzheimer's disease. Brain research bulletin. vol 147. 2020-04-06. PMID:30721766. |
the present findings suggested that q10 treatment offers neuroprotection against the detrimental effects of aβ on hippocampal synaptic plasticity via its antioxidant activity. |
2020-04-06 |
2023-08-13 |
rat |
| Douglas Affonso Formolo, Thomas Ho-Yin Lee, Suk-Yu Ya. Increasing Adiponergic System Activity as a Potential Treatment for Depressive Disorders. Molecular neurobiology. vol 56. issue 12. 2020-04-06. PMID:31140056. |
emerging evidence has suggested that adiponectin and the adiponectin receptor agonist, adiporon, could promote adult neurogenesis, dendritic and spine remodeling, and synaptic plasticity in the hippocampus, resulting in antidepressant effects in adult mice. |
2020-04-06 |
2023-08-13 |
mouse |
| Lei An, Jia Li, Le Luo, Peidong Huang, Peidong Liu, Chunzhi Tang, Wei Su. Prenatal melamine exposure impairs cognitive flexibility and hippocampal synaptic plasticity in adolescent and adult female rats. Pharmacology, biochemistry, and behavior. vol 186. 2020-04-02. PMID:31518600. |
prenatal melamine exposure impairs cognitive flexibility and hippocampal synaptic plasticity in adolescent and adult female rats. |
2020-04-02 |
2023-08-13 |
rat |
| Tina Zimmermann, Julia C Bartsch, Annika Beer, Ermelinda Lomazzo, Stephan Guggenhuber, Maren D Lange, Laura Bindila, Hans-Christian Pape, Beat Lut. Impaired anandamide/palmitoylethanolamide signaling in hippocampal glutamatergic neurons alters synaptic plasticity, learning, and emotional responses. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 8. 2020-03-31. PMID:30532004. |
impaired anandamide/palmitoylethanolamide signaling in hippocampal glutamatergic neurons alters synaptic plasticity, learning, and emotional responses. |
2020-03-31 |
2023-08-13 |
mouse |
| Gokul Krishna, Zhe Ying, Fernando Gomez-Pinill. Blueberry Supplementation Mitigates Altered Brain Plasticity and Behavior after Traumatic Brain Injury in Rats. Molecular nutrition & food research. vol 63. issue 15. 2020-03-31. PMID:31115168. |
traumatic brain injury (tbi) compromises neuronal function required for hippocampal synaptic plasticity and cognitive function. |
2020-03-31 |
2023-08-13 |
rat |
| Sarah M Neuner, Shengyuan Ding, Catherine C Kaczorowsk. Knockdown of heterochromatin protein 1 binding protein 3 recapitulates phenotypic, cellular, and molecular features of aging. Aging cell. vol 18. issue 1. 2020-03-30. PMID:30549219. |
to test the hypothesis that hp1bp3 mediates susceptibility to cognitive deficits via a role in neuronal excitability, we performed slice electrophysiology demonstrate transcriptional changes after hp1bp3 knockdown manifest functionally as a reduction in hippocampal neuronal intrinsic excitability and synaptic plasticity. |
2020-03-30 |
2023-08-13 |
Not clear |
| Steven J Girdler, Jamie E Confino, Mary E Woesne. Exercise as a Treatment for Schizophrenia: A Review. Psychopharmacology bulletin. vol 49. issue 1. 2020-03-30. PMID:30858639. |
although no clear etiology of schizophrenia has been discovered, many factors have been identified that contribute to the development of the disease, such as neurotransmitter alterations, decreased synaptic plasticity, and diminished hippocampal volume. |
2020-03-30 |
2023-08-13 |
Not clear |
| Yi-Ting Su, Shun-Fat Lau, Jacque P K Ip, Kit Cheung, Tom H T Cheung, Amy K Y Fu, Nancy Y I. α2-Chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 27. 2020-03-30. PMID:31209021. |
furthermore, α2-cko led to defects in hippocampal synaptic plasticity and anxiety/depression-like behaviors in mice. |
2020-03-30 |
2023-08-13 |
mouse |
| N A Beregovoi, M V Starostina, T V Lipin. Effects of Specific Inhibitor of Phosphodiesterase 7 at the Late Stage of Long-Term Potentiation in Murine Hippocampal Slices. Bulletin of experimental biology and medicine. vol 167. issue 4. 2020-03-30. PMID:31493257. |
these data attest to the involvement of phosphodiesterase 7 in the development of synaptic plasticity in the hippocampus. |
2020-03-30 |
2023-08-13 |
Not clear |
| Lenzie Ford, Emi Ling, Eric R Kandel, Luana Fiorit. CPEB3 inhibits translation of mRNA targets by localizing them to P bodies. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 36. 2020-03-24. PMID:31416913. |
the cytoplasmic polyadenylation element-binding protein 3 (cpeb3) regulates the translation of several mrnas important for long-term synaptic plasticity in the hippocampus. |
2020-03-24 |
2023-08-13 |
Not clear |
| Marta Sabariego, Antonia Schönwald, Brittney L Boublil, David T Zimmerman, Siavash Ahmadi, Nailea Gonzalez, Christian Leibold, Robert E Clark, Jill K Leutgeb, Stefan Leutge. Time Cells in the Hippocampus Are Neither Dependent on Medial Entorhinal Cortex Inputs nor Necessary for Spatial Working Memory. Neuron. vol 102. issue 6. 2020-03-23. PMID:31056352. |
therefore, mec is critical for providing stable and distinct spatial information to hippocampus, while working memory (wm) maintenance is likely supported either by local synaptic plasticity in hippocampus or by activity patterns elsewhere in the brain. |
2020-03-23 |
2023-08-13 |
rat |
| Corinne G Jolivalt, Alexandra Marquez, David Quach, Michelle C Navarro Diaz, Carlos Anaya, Betelhem Kifle, Nabeel Muttalib, Gabriela Sanchez, Lucy Guernsey, Mike Hefferan, Darrel R Smith, Paul Fernyhough, Karl Johe, Nigel A Calcut. Amelioration of Both Central and Peripheral Neuropathy in Mouse Models of Type 1 and Type 2 Diabetes by the Neurogenic Molecule NSI-189. Diabetes. vol 68. issue 11. 2020-03-17. PMID:31492662. |
nsi-189 is a new chemical entity that when orally administered promotes neurogenesis in the adult hippocampus, increases hippocampal volume, enhances synaptic plasticity, and reduces cognitive dysfunction. |
2020-03-17 |
2023-08-13 |
mouse |
| Edgar Bäumler, Lauren Strickland, Lucia Priviter. Molecular Underpinnings of Estradiol-Mediated Sexual Dimorphism of Synaptic Plasticity in the Hippocampus of Rodents. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 12. 2020-03-12. PMID:30894462. |
molecular underpinnings of estradiol-mediated sexual dimorphism of synaptic plasticity in the hippocampus of rodents. |
2020-03-12 |
2023-08-13 |
Not clear |
| Bin Liu, Jinxia Liu, Jinxia Zhang, Wenjing Mao, Shiying L. Effects of autophagy on synaptic-plasticity-related protein expression in the hippocampus CA1 of a rat model of vascular dementia. Neuroscience letters. vol 707. 2020-03-11. PMID:31163225. |
these findings suggest that autophagy may regulate synaptic plasticity in the hippocampus in a vd model of rats. |
2020-03-11 |
2023-08-13 |
rat |
| David J Titus, Timothy Johnstone, Nathan H Johnson, Sidney H London, Meghana Chapalamadugu, Derk Hogenkamp, Kelvin W Gee, Coleen M Atkin. Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury. PloS one. vol 14. issue 10. 2020-03-11. PMID:31581202. |
our results demonstrate that avl-3288 improves hippocampal synaptic plasticity, and learning and memory performance after tbi in the chronic recovery period. |
2020-03-11 |
2023-08-13 |
human |
| Mohammad Shabani, Fariba Ebrahimpoor, Maryam Arab Firouzjaei, Leila Kamali, Seyed Mostafa Shid Moosavi, Ali Noorafshan, Masoud Haghan. Modulation of sphingosine-1-phosphate receptor by FTY720 contributes in improvement of hepatic encephalopathy induced by bile duct ligation. Brain research bulletin. vol 146. 2020-03-10. PMID:30660717. |
the bdl led to considerable loss of hippocampal neurons and apoptosis, along with large impairments in their intrinsic electrophysiological properties, including decrease of firing frequency and increases of first spike latency (fsl), ahp amplitude, irregularity of firing, and half-width, as well as impaired long-term synaptic plasticity and memory. |
2020-03-10 |
2023-08-13 |
Not clear |
| Mei Li, Mingdan You, Siyao Li, Zhenmin Qiu, Yi Wan. Effects of maternal exposure to nonylphenol on learning and memory in offspring involve inhibition of BDNF-PI3K/Akt signaling. Brain research bulletin. vol 146. 2020-03-10. PMID:30660719. |
we also investigated the activation of bdnf-pi3k/akt signaling and the expression of its target protein psd-95 in offspring hippocampus, which are curial for the synaptic plasticity and learning and memory. |
2020-03-10 |
2023-08-13 |
Not clear |
| Maja Djurisic, Barbara K Brott, Nay L Saw, Mehrdad Shamloo, Carla J Shat. Activity-dependent modulation of hippocampal synaptic plasticity via PirB and endocannabinoids. Molecular psychiatry. vol 24. issue 8. 2020-03-09. PMID:29670176. |
activity-dependent modulation of hippocampal synaptic plasticity via pirb and endocannabinoids. |
2020-03-09 |
2023-08-13 |
mouse |
| Maofang Hei, Peng Chen, Shuzhong Wang, Xuzhao Li, Mingrui Xu, Xiaoyan Zhu, Yi Wang, Jinyou Duan, Yong Huang, Shanting Zha. Effects of chronic mild stress induced depression on synaptic plasticity in mouse hippocampus. Behavioural brain research. vol 365. 2020-03-09. PMID:30825464. |
effects of chronic mild stress induced depression on synaptic plasticity in mouse hippocampus. |
2020-03-09 |
2023-08-13 |
mouse |
| Maofang Hei, Peng Chen, Shuzhong Wang, Xuzhao Li, Mingrui Xu, Xiaoyan Zhu, Yi Wang, Jinyou Duan, Yong Huang, Shanting Zha. Effects of chronic mild stress induced depression on synaptic plasticity in mouse hippocampus. Behavioural brain research. vol 365. 2020-03-09. PMID:30825464. |
strong evidence proved the important role of hippocampal synaptic plasticity in the mechanism of depression. |
2020-03-09 |
2023-08-13 |
mouse |