| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alba Navarro-Romero, Anna Vázquez-Oliver, Maria Gomis-González, Carlos Garzón-Montesinos, Rafael Falcón-Moya, Antoni Pastor, Elena Martín-García, Nieves Pizarro, Arnau Busquets-Garcia, Jean-Michel Revest, Pier-Vincenzo Piazza, Fátima Bosch, Mara Dierssen, Rafael de la Torre, Antonio Rodríguez-Moreno, Rafael Maldonado, Andrés Ozait. Cannabinoid type-1 receptor blockade restores neurological phenotypes in two models for Down syndrome. Neurobiology of disease. vol 125. 2019-12-16. PMID:30685352. |
concomitant with this result, pharmacological inhibition of cb1r restored memory deficits, hippocampal synaptic plasticity and adult neurogenesis in the subgranular zone of the dentate gyrus. |
2019-12-16 |
2023-08-13 |
mouse |
| Li Lin, Jie Cao, Shu-Sheng Yang, Zheng-Qi Fu, Peng Zeng, Jiang Chu, Lin-Na Ning, Teng Zhang, Yan Shi, Qing Tian, Xin-Wen Zhou, Jian-Zhi Wan. Endoplasmic reticulum stress induces spatial memory deficits by activating GSK-3. Journal of cellular and molecular medicine. vol 22. issue 7. 2019-12-13. PMID:29675957. |
simultaneous inhibition of gsk-3β by hippocampal infusion of sb216763 (sb) attenuated tm-induced upr and spatial memory impairment with restoration of ps129-creb and synaptic plasticity. |
2019-12-13 |
2023-08-13 |
rat |
| I B Mikheeva, A E Malkov, L L Pavlik, V I Arkhipov, S G Levi. Effect of Interleukin-10 on Localization of AMPA Receptors in Synapses during Long-Term Posttetanic Potentiation in Cultured Hippocampal Slices. Bulletin of experimental biology and medicine. vol 167. issue 1. 2019-12-11. PMID:31183657. |
it is assumed that activation of neuronal il-10 receptors affects the distribution of ampa receptors in axo-spinous synapses of hippocampal field ca1 through interplay of intracellular signaling pathways, thereby participating in the mechanisms of synaptic plasticity under normal conditions. |
2019-12-11 |
2023-08-13 |
Not clear |
| Martina Bürge, Stephan Kratzer, Corinna Mattusch, Carolin Hofmann, Matthias Kreuzer, Christopher G Parsons, Gerhard Ramme. The anaesthetic xenon partially restores an amyloid beta-induced impairment in murine hippocampal synaptic plasticity. Neuropharmacology. vol 151. 2019-12-10. PMID:30940537. |
the anaesthetic xenon partially restores an amyloid beta-induced impairment in murine hippocampal synaptic plasticity. |
2019-12-10 |
2023-08-13 |
Not clear |
| Dafan Yu, Zhenxing Cheng, Abdoulaye Idriss Ali, Jiamin Wang, Kai Le, Enkhmurun Chibaatar, Yijing Gu. Chronic Unexpected Mild Stress Destroys Synaptic Plasticity of Neurons through a Glutamate Transporter, GLT-1, of Astrocytes in the Ischemic Stroke Rat. Neural plasticity. vol 2019. 2019-12-10. PMID:31019528. |
chronic unexpected mild stress (cums) destroys synaptic plasticity of hippocampal regenerated neurons that may be involved in the occurrence of poststroke depression. |
2019-12-10 |
2023-08-13 |
rat |
| Audrey Branch, Amy Monasterio, Grace Blair, James J Knierim, Michela Gallagher, Rebecca P Haberma. Aged rats with preserved memory dynamically recruit hippocampal inhibition in a local/global cue mismatch environment. Neurobiology of aging. vol 76. 2019-12-06. PMID:30716540. |
although behavioral measures and hippocampal gene induction associated with neural activity and synaptic plasticity were similar across age groups, a marker for inhibitory interneuron function in the hippocampal formation was distinctively increased only in aged rats but not in young adults. |
2019-12-06 |
2023-08-13 |
rat |
| Xian Wu, Caihong Liu, Liang Chen, Yi-Feng Du, Mei Hu, Miranda N Reed, Yan Long, Vishnu Suppiramaniam, Hao Hong, Su-Su Tan. Protective effects of tauroursodeoxycholic acid on lipopolysaccharide-induced cognitive impairment and neurotoxicity in mice. International immunopharmacology. vol 72. 2019-12-03. PMID:30986644. |
tudca treatment also ameliorated synaptic plasticity impairments by increasing the ratio of mbdnf/probdnf, the number of dendritic spines and the expression of synapse-associated proteins in the hippocampus. |
2019-12-03 |
2023-08-13 |
mouse |
| Yingchun Shang, Xin Wang, Fangjuan Li, Tao Yin, Jianhai Zhang, Tao Zhan. rTMS Ameliorates Prenatal Stress-Induced Cognitive Deficits in Male-Offspring Rats Associated With BDNF/TrkB Signaling Pathway. Neurorehabilitation and neural repair. vol 33. issue 4. 2019-11-29. PMID:30979358. |
growing evidences suggest that brain-derived neurotrophic factor/tropomyosin receptor kinase b (bdnf/trkb) plays a key role in the regulation of hippocampal synaptic plasticity in a prenatal stress (pns) rat model. |
2019-11-29 |
2023-08-13 |
rat |
| Edward G Meloni, Karen T Kaye, Archana Venkataraman, William A Carlezo. PACAP increases Arc/Arg 3.1 expression within the extended amygdala after fear conditioning in rats. Neurobiology of learning and memory. vol 157. 2019-11-25. PMID:30458282. |
pacap can alter synaptic plasticity and has direct actions on neurons in the amygdala and hippocampus that could contribute to its acute and persistent effects on the consolidation and expression of conditioned fear. |
2019-11-25 |
2023-08-13 |
rat |
| Christelle Bon, Georg Andrees Böhme, Adam Doble, Jean-Marie Stutzmann, Jean-Charles Blanchar. A Role for Nitric Oxide in Long-term Potentiation. The European journal of neuroscience. vol 4. issue 5. 2019-11-20. PMID:12106350. |
here we provide evidence that endogenous nitric oxide production is necessary for synaptic plasticity in the ca1 hippocampus of the rat. |
2019-11-20 |
2023-08-12 |
rat |
| R Nistico', S Piccinin, C Schepisi, C Ferraina, M Laurenza, D Mango, M Graziani, F Nicoletti, N B Mercuri, M Feligion. Pharmacological modulation of long-term potentiation in animal models of Alzheimer's disease. Journal of biological regulators and homeostatic agents. vol 27. issue 2 Suppl. 2019-11-20. PMID:24813314. |
this review recapitulates the emerging disease-modifying strategies utilized to modulate hippocampal synaptic plasticity with particular attention to approaches targeting ligand-gated ion channels, g-protein-coupled receptors (gpcrs), receptor tyrosine kinases (rtks) and epigenetic mechanisms. |
2019-11-20 |
2023-08-13 |
Not clear |
| F Errico, A Di Maio, V Marsili, M Squillace, D Vitucci, F Napolitano, A Usiell. Bimodal effect of D-aspartate on brain aging processes: insights from animal models. Journal of biological regulators and homeostatic agents. vol 27. issue 2 Suppl. 2019-11-20. PMID:24813315. |
however, if exposure to elevated levels of d-asp lasts for the entire lifetime of mice, enhancement of synaptic plasticity turns into a dramatic worsening, thus triggering an acceleration of the nmdar-dependent aging processes in the hippocampus. |
2019-11-20 |
2023-08-13 |
mouse |
| Jafar Doost Mohammadpour, Narges Hosseinmardi, Mahyar Janahmadi, Yaghoub Fathollahi, Fereshteh Motamedi, Kambiz Rohampou. Non-selective NSAIDs improve the amyloid-β-mediated suppression of memory and synaptic plasticity. Pharmacology, biochemistry, and behavior. vol 132. 2019-11-20. PMID:25697476. |
in the present study effects of non-selective nsaids (aspirin and sodium salicylate) on associated memory impairment as well as aβ-mediated suppression of synaptic plasticity in the hippocampus were examined. |
2019-11-20 |
2023-08-13 |
rat |
| Pedro Cisternas, Paulina Salazar, Felipe G Serrano, Carla Montecinos-Oliva, Sebastián B Arredondo, Lorena Varela-Nallar, Salesa Barja, Carlos P Vio, Fernando Gomez-Pinilla, Nibaldo C Inestros. Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance. Biochimica et biophysica acta. vol 1852. issue 11. 2019-11-20. PMID:26300486. |
fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance. |
2019-11-20 |
2023-08-13 |
mouse |
| Pedro Cisternas, Paulina Salazar, Felipe G Serrano, Carla Montecinos-Oliva, Sebastián B Arredondo, Lorena Varela-Nallar, Salesa Barja, Carlos P Vio, Fernando Gomez-Pinilla, Nibaldo C Inestros. Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance. Biochimica et biophysica acta. vol 1852. issue 11. 2019-11-20. PMID:26300486. |
there was a dramatic deterioration in the capacity of the hippocampus to sustain synaptic plasticity in the forms of long-term potentiation (ltp) and long-term depression (ltd). |
2019-11-20 |
2023-08-13 |
mouse |
| Hiranya Pintana, Pongpan Tanajak, Wasana Pratchayasakul, Piangkwan Sa-Nguanmoo, Titikorn Chunchai, Pattarapong Satjaritanun, Linlada Leelarphat, Nipon Chattipakorn, Siriporn C Chattipakor. Energy restriction combined with dipeptidyl peptidase-4 inhibitor exerts neuroprotection in obese male rats. The British journal of nutrition. 2019-11-20. PMID:27852331. |
however, the effects of er or the combination with vildagliptin on brain insulin sensitivity, brain mitochondrial function, hippocampal synaptic plasticity and cognitive function in obese insulin-resistant rats have never been investigated. |
2019-11-20 |
2023-08-13 |
rat |
| Hiranya Pintana, Pongpan Tanajak, Wasana Pratchayasakul, Piangkwan Sa-Nguanmoo, Titikorn Chunchai, Pattarapong Satjaritanun, Linlada Leelarphat, Nipon Chattipakorn, Siriporn C Chattipakor. Energy restriction combined with dipeptidyl peptidase-4 inhibitor exerts neuroprotection in obese male rats. The British journal of nutrition. 2019-11-20. PMID:27852331. |
we hypothesised that er with ddp-4 inhibitor exerts better efficacy than er alone in improving cognition in obese insulin-resistant male rats by restoring brain insulin sensitivity, brain mitochondrial function and hippocampal synaptic plasticity. |
2019-11-20 |
2023-08-13 |
rat |
| Hiranya Pintana, Pongpan Tanajak, Wasana Pratchayasakul, Piangkwan Sa-Nguanmoo, Titikorn Chunchai, Pattarapong Satjaritanun, Linlada Leelarphat, Nipon Chattipakorn, Siriporn C Chattipakor. Energy restriction combined with dipeptidyl peptidase-4 inhibitor exerts neuroprotection in obese male rats. The British journal of nutrition. 2019-11-20. PMID:27852331. |
at the end of the treatment, cognitive function, metabolic parameters, brain insulin sensitivity, hippocampal synaptic plasticity and brain mitochondrial function were determined. |
2019-11-20 |
2023-08-13 |
rat |
| Hiranya Pintana, Pongpan Tanajak, Wasana Pratchayasakul, Piangkwan Sa-Nguanmoo, Titikorn Chunchai, Pattarapong Satjaritanun, Linlada Leelarphat, Nipon Chattipakorn, Siriporn C Chattipakor. Energy restriction combined with dipeptidyl peptidase-4 inhibitor exerts neuroprotection in obese male rats. The British journal of nutrition. 2019-11-20. PMID:27852331. |
although hfd-fed rats treated with er and er plus vildagliptin showed restored peripheral insulin sensitivity and improved lipid profiles, only er plus vildagliptin rats had restored brain insulin sensitivity, brain mitochondrial function, hippocampal synaptic plasticity and cognitive function. |
2019-11-20 |
2023-08-13 |
rat |
| Ying Li, Qiang-Long You, Sheng-Rong Zhang, Wei-Yuan Huang, Wen-Jun Zou, Wei Jie, Shu-Ji Li, Ji-Hong Liu, Chuang-Ye Lv, Jin Cong, Yu-Ying Hu, Tian-Ming Gao, Jian-Ming L. Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity. Molecular neurobiology. 2019-11-20. PMID:28421537. |
satb2 ablation impairs hippocampus-based long-term spatial memory and short-term working memory and immediate early genes (iegs)-mediated hippocampal synaptic plasticity. |
2019-11-20 |
2023-08-13 |
mouse |