| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu-Ju Chen, Shin-Meng Deng, Hui-Wen Chen, Chi-Hui Tsao, Wei-Ting Chen, Sin-Jhong Cheng, Hsien-Sung Huang, Bertrand Chin-Ming Tan, Martin M Matzuk, Jonathan Flint, Guo-Jen Huan. Follistatin mediates learning and synaptic plasticity via regulation of Asic4 expression in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 39. 2021-10-05. PMID:34544873. |
follistatin mediates learning and synaptic plasticity via regulation of asic4 expression in the hippocampus. |
2021-10-05 |
2023-08-13 |
Not clear |
| Theresa Wiesner, Anthony Bilodeau, Renaud Bernatchez, Andréanne Deschênes, Bastian Raulier, Paul De Koninck, Flavie Lavoie-Cardina. Activity-Dependent Remodeling of Synaptic Protein Organization Revealed by High Throughput Analysis of STED Nanoscopy Images. Frontiers in neural circuits. vol 14. 2021-10-04. PMID:33177994. |
to characterize changes in the organization of synaptic nanodomains during synaptic plasticity over a large population of synapses, we combined stimulated emission depletion (sted) nanoscopy with a python-based statistical object distance analysis (pysoda), in dissociated cultured hippocampal circuits exposed to treatments driving different forms of synaptic plasticity. |
2021-10-04 |
2023-08-13 |
Not clear |
| Blanca Marin Bosch, Aurélien Bringard, Maria G Logrieco, Estelle Lauer, Nathalie Imobersteg, Aurélien Thomas, Guido Ferretti, Sophie Schwartz, Kinga Iglo. A single session of moderate intensity exercise influences memory, endocannabinoids and brain derived neurotrophic factor levels in men. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34257382. |
regular physical exercise enhances memory functions, synaptic plasticity in the hippocampus, and brain derived neurotrophic factor (bdnf) levels. |
2021-10-04 |
2023-08-13 |
human |
| Patricia Soriano Roque, Mehdi Hooshmandi, Laura Neagu-Lund, Shelly Yin, Noosha Yousefpour, Hiroaki Sato, Tamaki Sato, Yosuke Nakadate, Akiko Kawakami, Soroush Tahmasebi, Alfredo Ribeiro-da-Silva, Christos G Gkogkas, Masha Prager-Khoutorsky, Thomas Schricker, Linda Wykes, Arkady Khoutorsk. Intranasal insulin rescues repeated anesthesia-induced deficits in synaptic plasticity and memory and prevents apoptosis in neonatal mice via mTORC1. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34326413. |
our study demonstrates that intranasal insulin prevents general anesthesia-induced apoptosis of hippocampal cells, and deficits in synaptic plasticity and memory, and suggests that the rescue effect is mediated via mtorc1/4e-bp2 signaling. |
2021-10-04 |
2023-08-13 |
mouse |
| A H Alhowail, M Aldubaya. Recent progress in the elucidation of the mechanisms of chemotherapy-induced cognitive impairment. European review for medical and pharmacological sciences. vol 25. issue 18. 2021-10-04. PMID:34604972. |
according to the reviewed studies, the mechanisms by which chemotherapy could cause chemobrain include disruption of hippocampal cell proliferation and neurogenesis, hormonal changes, increased oxidative stress and reactive oxygen species production, chronic increase in inflammation, and alterations in synaptic plasticity and long-term potentiation. |
2021-10-04 |
2023-08-13 |
Not clear |
| Elahe Barfi, Ava Modirzadeh Tehrani, Mojtaba Mohammadpanah, Mahdi Eskandarian Boroujeni, Gholam Hossein Meftahi, Yousef Sadeghi, Samira Eziy, Aysan Khatmi, Mohammad Amin Abdollahifar, Zeynab Ghorbani, Abbas Aliaghae. The role of Tetrahydrocannabinol in inducing disrupted signaling cascades, hippocampal atrophy and memory defects. Journal of chemical neuroanatomy. vol 113. 2021-10-01. PMID:33689904. |
we also detected several dysregulated signaling pathways involved in synaptic plasticity as well as cell-cell interaction in the hippocampus of thc-treated rats. |
2021-10-01 |
2023-08-13 |
rat |
| Gabriele Di Cicco, Emanuela Marzano, Luisa Iacovelli, Roberta Celli, Gilles van Luijtelaar, Ferdinando Nicoletti, Richard T Ngomba, Mark J Wal. Group I metabotropic glutamate receptor-mediated long term depression is disrupted in the hippocampus of WAG/Rij rats modelling absence epilepsy. Neuropharmacology. vol 196. 2021-10-01. PMID:34197893. |
here we report that some forms of hippocampal synaptic plasticity are abnormal in symptomatic wistar albino glaxo/rijswijk (wag/rij) rats. |
2021-10-01 |
2023-08-13 |
rat |
| Gabriele Di Cicco, Emanuela Marzano, Luisa Iacovelli, Roberta Celli, Gilles van Luijtelaar, Ferdinando Nicoletti, Richard T Ngomba, Mark J Wal. Group I metabotropic glutamate receptor-mediated long term depression is disrupted in the hippocampus of WAG/Rij rats modelling absence epilepsy. Neuropharmacology. vol 196. 2021-10-01. PMID:34197893. |
these findings suggest that abnormalities in hippocampal mglu5 receptor-dependent synaptic plasticity are associated with the pathological phenotype of wag/rij rats. |
2021-10-01 |
2023-08-13 |
rat |
| Caitlin K Posillic. Three's Company: Neuroimmune activation, sex, and memory at the tripartite synapse. Brain, behavior, & immunity - health. vol 16. 2021-10-01. PMID:34589812. |
an important remaining component to this system is the conclusive evidence of sex differences in hippocampal plasticity mechanisms, hormone modulation of synaptic plasticity, functional properties of hippocampal neurons, and in neuroimmune activation. |
2021-10-01 |
2023-08-13 |
Not clear |
| Xin Zhao, Alejandro N Rondón-Ortiz, Erika P Lima, Madeline Puracchio, Ryland C Roderick, Amanda C Kentne. Therapeutic efficacy of environmental enrichment on behavioral, endocrine, and synaptic alterations in an animal model of maternal immune activation. Brain, behavior, & immunity - health. vol 3. 2021-09-29. PMID:32368757. |
within the prefrontal cortex, hippocampus, amygdala, and hypothalamus, mia and ee altered the mrna expression of several genes associated with resiliency and synaptic plasticity in both sexes. |
2021-09-29 |
2023-08-13 |
human |
| Dan Wu, Fengjuan Wu, Ren Lin, Yuan Meng, Wei Wei, Qi Sun, Lihong Ji. Impairment of learning and memory induced by perinatal exposure to BPA is associated with ERα-mediated alterations of synaptic plasticity and PKC/ERK/CREB signaling pathway in offspring rats. Brain research bulletin. vol 161. 2021-09-29. PMID:32380187. |
we aimed to investigate whether the impairment of learning and memory induced by perinatal exposure to bpa was associated with the hippocampal estrogen receptor α (erα)-mediated synaptic plasticity and pkc/erk/creb signaling pathway in different sex offspring rats. |
2021-09-29 |
2023-08-13 |
rat |
| Ekta Kumari, Kai Li, Zhuo Yang, Tao Zhan. Tacrine accelerates spatial long-term memory via improving impaired neural oscillations and modulating GAD isomers including neuro-receptors in the hippocampus of APP/PS1 AD mice. Brain research bulletin. vol 161. 2021-09-29. PMID:32473192. |
furthermore, our results implied that tacrine strongly improve the patterns of neural oscillations, and hippocampal synaptic plasticity in the 6th month old app-ps1 double transgenic ad-tac mice via changing the theta and alpha power spectra including with the improvement in theta, alpha and gamma synchronization. |
2021-09-29 |
2023-08-13 |
mouse |
| Zhen Lan, Zhaoyou Meng, Biyao Lian, Mengying Liu, Tao Sun, Huan Sun, Zhi Liu, Zhenxin Hu, Qiang Guo, Jiqiang Zhan. Hippocampal Aromatase Knockdown Aggravates Ovariectomy-Induced Spatial Memory Impairment, Aβ Accumulation and Neural Plasticity Deficiency in Adult Female Mice. Neurochemical research. vol 46. issue 5. 2021-09-27. PMID:33559105. |
in recent years, high levels of aromatase (arom), the estrogen synthase, has been localized in hippocampus; and this hippocampus-derived e2 seems to be functional in synaptic plasticity and spatial memory as ovarian e2 does. |
2021-09-27 |
2023-08-13 |
mouse |
| Jian Yu, Li Ren, Su Min, Feng Lv, Jie Luo, Ping Li, Yuxi Zhan. Inhibition of CB1 receptor alleviates electroconvulsive shock-induced memory impairment by regulating hippocampal synaptic plasticity in depressive rats. Psychiatry research. vol 300. 2021-09-27. PMID:33848965. |
inhibition of cb1 receptor alleviates electroconvulsive shock-induced memory impairment by regulating hippocampal synaptic plasticity in depressive rats. |
2021-09-27 |
2023-08-13 |
rat |
| Jian Yu, Li Ren, Su Min, Feng Lv, Jie Luo, Ping Li, Yuxi Zhan. Inhibition of CB1 receptor alleviates electroconvulsive shock-induced memory impairment by regulating hippocampal synaptic plasticity in depressive rats. Psychiatry research. vol 300. 2021-09-27. PMID:33848965. |
taken together, we identified that cb1r is involved in the ecs-induced spatial learning and memory impairment and inhibition of cb1r facilitates the recovery of memory impairment and hippocampal synaptic plasticity, without interfering with the therapeutic effects of ecs in depressed rats. |
2021-09-27 |
2023-08-13 |
rat |
| Ye Wang, Amy K Y Fu, Nancy Y I. IL-33/ST2 Signaling Regulates Synaptic Plasticity and Homeostasis in the Adult Hippocampal Circuitry. DNA and cell biology. vol 40. issue 9. 2021-09-23. PMID:34297618. |
il-33/st2 signaling regulates synaptic plasticity and homeostasis in the adult hippocampal circuitry. |
2021-09-23 |
2023-08-13 |
Not clear |
| Ye Wang, Amy K Y Fu, Nancy Y I. IL-33/ST2 Signaling Regulates Synaptic Plasticity and Homeostasis in the Adult Hippocampal Circuitry. DNA and cell biology. vol 40. issue 9. 2021-09-23. PMID:34297618. |
glial cells, including astrocytes and microglia, actively regulate hippocampal synaptic plasticity by coordinating the neuronal activity-induced synaptic changes at the circuit level. |
2021-09-23 |
2023-08-13 |
Not clear |
| Ye Wang, Amy K Y Fu, Nancy Y I. IL-33/ST2 Signaling Regulates Synaptic Plasticity and Homeostasis in the Adult Hippocampal Circuitry. DNA and cell biology. vol 40. issue 9. 2021-09-23. PMID:34297618. |
further investigations of how il-33/st2 signaling is regulated in a region-specific manner as well as its diverse functions in glia-synapse communications in the adult hippocampal circuitry will provide insights into the nature of hippocampal synaptic plasticity and homeostasis in health and disease. |
2021-09-23 |
2023-08-13 |
Not clear |
| Jin-Lan Huang, Fan Zhang, Min Su, Jiaxin Li, Wen Yi, Li-Xiang Hou, Si-Man Yang, Jin-Yuan Liu, Hao-An Zhang, Tengfei Ma, Deng-Pan W. MeCP2 prevents age-associated cognitive decline via restoring synaptic plasticity in a senescence-accelerated mouse model. Aging cell. vol 20. issue 9. 2021-09-23. PMID:34363729. |
overexpression of hippocampal mecp2 could elevate synaptic plasticity and cognitive function in samp8 mice, while knockdown of mecp2 impaired synaptic plasticity and cognitive function in senescence accelerated-resistant 1 (samr1) mice. |
2021-09-23 |
2023-08-13 |
mouse |
| Gaochun Zhu, Qian Zhu, Wei Zhang, Chen Hui, Yuwen Li, Meiyuan Yang, Shimin Pang, Yaobing Li, Guoyong Xue, Hongping Che. Mitochondrial uncoupling protein 2 is regulated through heterogeneous nuclear ribonucleoprotein K in lead exposure models. Journal of environmental science and health. Part C, Toxicology and carcinogenesis. vol 39. issue 1. 2021-09-22. PMID:33576715. |
synaptic plasticity plays an important role in learning and memory in the developing hippocampus. |
2021-09-22 |
2023-08-13 |
rat |