| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eve Honoré, Abdessattar Khlaifia, Anthony Bosson, Jean-Claude Lacaill. Hippocampal Somatostatin Interneurons, Long-Term Synaptic Plasticity and Memory. Frontiers in neural circuits. vol 15. 2021-07-16. PMID:34149368. |
we describe the long-term synaptic plasticity that takes place at the excitatory synapses of som interneurons, its singular induction and expression mechanisms, as well as the consequences of these changes on the hippocampal network, learning, and memory. |
2021-07-16 |
2023-08-13 |
mouse |
| Saeed Esmaeili-Mahani, Elham Haghparast, Akram Nezhadi, Mehdi Abbasnejad, Vahid Sheiban. Apelin-13 prevents hippocampal synaptic plasticity impairment in Parkinsonism rats. Journal of chemical neuroanatomy. vol 111. 2021-07-15. PMID:33161074. |
apelin-13 prevents hippocampal synaptic plasticity impairment in parkinsonism rats. |
2021-07-15 |
2023-08-13 |
rat |
| Ting Xu, Jiao Liu, Xin-Rui Li, Yinghua Yu, Xuan Luo, Xian Zheng, Yuan Cheng, Pei-Quan Yu, Yi Li. The mTOR/NF-κB Pathway Mediates Neuroinflammation and Synaptic Plasticity in Diabetic Encephalopathy. Molecular neurobiology. vol 58. issue 8. 2021-07-15. PMID:33860440. |
in the present study, we investigated whether mtor regulates the nf-κb signaling pathway to modulate inflammatory cytokines and synaptic plasticity in hippocampal neurons. |
2021-07-15 |
2023-08-13 |
mouse |
| Ting Xu, Jiao Liu, Xin-Rui Li, Yinghua Yu, Xuan Luo, Xian Zheng, Yuan Cheng, Pei-Quan Yu, Yi Li. The mTOR/NF-κB Pathway Mediates Neuroinflammation and Synaptic Plasticity in Diabetic Encephalopathy. Molecular neurobiology. vol 58. issue 8. 2021-07-15. PMID:33860440. |
the inhibition of mtor and nf-κb suppressed mtor/nf-κb signaling pathway, increased synaptic proteins, and improved ultrastructural synaptic plasticity in the hippocampus of diabetic mice. |
2021-07-15 |
2023-08-13 |
mouse |
| Jens Schepers, Christine Gebhardt, Alexander Bracke, Ina Eiffler, Oliver von Bohlen Und Halbac. Structural and functional consequences in the amygdala of leptin-deficient mice. Cell and tissue research. vol 382. issue 2. 2021-07-14. PMID:32789683. |
our results indicate that amygdalar and hippocampal synaptic plasticity are regulated in different ways by leptin deficiency in accordance with the different functions of these limbic structures in stress and anxiety. |
2021-07-14 |
2023-08-13 |
mouse |
| Masoomeh Nazifi, Manoochehr Ashrafpoor, Shahrbanoo Oryan, Delaram Eslimi Esfahani, Ali Akbar Moghadamni. Neurotoxic effects of high-dose piperine on hippocampal synaptic transmission and synaptic plasticity in a rat model of memory impairment. Neurotoxicology. vol 79. 2021-07-13. PMID:32360092. |
neurotoxic effects of high-dose piperine on hippocampal synaptic transmission and synaptic plasticity in a rat model of memory impairment. |
2021-07-13 |
2023-08-13 |
rat |
| Elham Mohamadi-Jorjafki, Mehdi Abbasnejad, Razieh Kooshki, Saeed Esmaeili-Mahani, Maryam Raoo. Mode of delivery alters dental pulp nociception and pain-induced changes in cognitive performance in adults male rats. Canadian journal of physiology and pharmacology. vol 98. issue 10. 2021-07-13. PMID:32516558. |
additionally, in vivo recording of field excitatory postsynaptic potential (fepsp) in the ca1 of the hippocampus was used to verify synaptic plasticity. |
2021-07-13 |
2023-08-13 |
rat |
| Jinzi Wu, Yan Dou, Warren C Ladige. Adverse Neurological Effects of Short-Term Sleep Deprivation in Aging Mice Are Prevented by SS31 Peptide. Clocks & sleep. vol 2. issue 3. 2021-07-13. PMID:33089207. |
in sleep deprived mice treated with ss31, learning impairment was prevented, brain mitochondrial atp levels and synaptic plasticity regulatory proteins were restored, and reactive oxygen species (ros) and inflammatory cytokines levels were decreased in the hippocampus. |
2021-07-13 |
2023-08-13 |
mouse |
| Marcin Wyroślak, Katarzyna Lebida, Jerzy W Mozrzyma. Induction of Inhibitory Synaptic Plasticity Enhances Tonic Current by Increasing the Content of α5-Subunit Containing GABA Neuroscience. vol 467. 2021-07-12. PMID:34033868. |
induction of inhibitory synaptic plasticity enhances tonic current by increasing the content of α5-subunit containing gaba it is known that besides synaptic inhibition, there is a persistent component of inhibitory drive mediated by tonic currents which is believed to mediate majority of the total inhibitory charge in hippocampal neurons. |
2021-07-12 |
2023-08-13 |
Not clear |
| Jana Lubec, Predrag Kalaba, Ahmed M Hussein, Daniel Daba Feyissa, Mohamed H Kotob, Rasha R Mahmmoud, Oliver Wieder, Arthur Garon, Claudia Sagheddu, Marija Ilic, Vladimir Dragačević, Anita Cybulska-Klosowicz, Martin Zehl, Judith Wackerlig, Simone B Sartori, Karl Ebner, Shima Kouhnavardi, Alexander Roller, Natalie Gajic, Marco Pistis, Nicolas Singewald, Johann Jakob Leban, Volker Korz, Jovana Malikovic, Roberto Plasenzotti, Harald H Sitte, Francisco J Monje, Thierry Langer, Ernst Urban, Christian Pifl, Gert Lube. Reinstatement of synaptic plasticity in the aging brain through specific dopamine transporter inhibition. Molecular psychiatry. 2021-07-10. PMID:34244620. |
we find both a potentiation of neurotransmission and coincident restoration of dendritic spines in the dorsal hippocampus, indicative of reinstatement of dopamine-induced synaptic plasticity in aging rodents. |
2021-07-10 |
2023-08-13 |
rat |
| Lily R Aleksandrova, Yu Tian Wang, Anthony G Phillip. Ketamine and its metabolite, (2R,6R)-HNK, restore hippocampal LTP and long-term spatial memory in the Wistar-Kyoto rat model of depression. Molecular brain. vol 13. issue 1. 2021-07-08. PMID:32546197. |
accumulating evidence implicates dysregulation of hippocampal synaptic plasticity in the pathophysiology of depression. |
2021-07-08 |
2023-08-13 |
rat |
| Lily R Aleksandrova, Yu Tian Wang, Anthony G Phillip. Ketamine and its metabolite, (2R,6R)-HNK, restore hippocampal LTP and long-term spatial memory in the Wistar-Kyoto rat model of depression. Molecular brain. vol 13. issue 1. 2021-07-08. PMID:32546197. |
we investigated ketamine's effects on in vivo dorsal hippocampal (dhpc) synaptic plasticity and their role in mediating aspects of antidepressant activity in the wistar-kyoto (wky) model of depression. |
2021-07-08 |
2023-08-13 |
rat |
| Yun Fan, Mei-Chuan Chou, Yen-Chin Liu, Ching-Kuan Liu, Chu-Huang Chen, Shiou-Lan Che. Intermittent Hypoxia Activates N-Methyl-D-Aspartate Receptors to Induce Anxiety Behaviors in a Mouse Model of Sleep-Associated Apnea. Molecular neurobiology. vol 58. issue 7. 2021-07-06. PMID:33660202. |
to evaluate how ih alters neuronal function to yield anxiety-like behavior and cognitive dysfunction, we examined synaptic plasticity and neuronal inflammation in related brain areas, including the medial prefrontal cortex (mpfc), striatum, and hippocampus. |
2021-07-06 |
2023-08-13 |
mouse |
| Chun-An Chen, Wei Wang, Steen E Pedersen, Ayush Raman, Michelle L Seymour, Fernanda R Ruiz, Anping Xia, Meike E van der Heijden, Li Wang, Jiani Yin, Joanna Lopez, Megan E Rech, Richard A Lewis, Samuel M Wu, Zhandong Liu, Fred A Pereira, Robia G Pautler, Huda Y Zoghbi, Christian P Schaa. Nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of Bosch-Boonstra-Schaaf optic atrophy syndrome and show impaired hippocampal synaptic plasticity. Human molecular genetics. vol 29. issue 5. 2021-07-05. PMID:31600777. |
nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of bosch-boonstra-schaaf optic atrophy syndrome and show impaired hippocampal synaptic plasticity. |
2021-07-05 |
2023-08-13 |
mouse |
| Chun-An Chen, Wei Wang, Steen E Pedersen, Ayush Raman, Michelle L Seymour, Fernanda R Ruiz, Anping Xia, Meike E van der Heijden, Li Wang, Jiani Yin, Joanna Lopez, Megan E Rech, Richard A Lewis, Samuel M Wu, Zhandong Liu, Fred A Pereira, Robia G Pautler, Huda Y Zoghbi, Christian P Schaa. Nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of Bosch-Boonstra-Schaaf optic atrophy syndrome and show impaired hippocampal synaptic plasticity. Human molecular genetics. vol 29. issue 5. 2021-07-05. PMID:31600777. |
these results suggest that a deficit or alteration in hippocampal synaptic plasticity may contribute to the intellectual disability frequently seen in bbsoas. |
2021-07-05 |
2023-08-13 |
mouse |
| Chun-An Chen, Wei Wang, Steen E Pedersen, Ayush Raman, Michelle L Seymour, Fernanda R Ruiz, Anping Xia, Meike E van der Heijden, Li Wang, Jiani Yin, Joanna Lopez, Megan E Rech, Richard A Lewis, Samuel M Wu, Zhandong Liu, Fred A Pereira, Robia G Pautler, Huda Y Zoghbi, Christian P Schaa. Nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of Bosch-Boonstra-Schaaf optic atrophy syndrome and show impaired hippocampal synaptic plasticity. Human molecular genetics. vol 29. issue 5. 2021-07-05. PMID:31600777. |
the discovery of impaired hippocampal synaptic plasticity in the heterozygous mouse model sheds light on the pathophysiology of altered memory and cognitive function in bbsoas. |
2021-07-05 |
2023-08-13 |
mouse |
| Kyle A Brown, Jessica M Carpenter, Collin J Preston, Helaina D Ludwig, Kendall B Clay, Donald A Harn, Thomas Norberg, John J Wagner, Nikolay M Filipo. Lacto-N-fucopentaose-III ameliorates acute and persisting hippocampal synaptic plasticity and transmission deficits in a Gulf War Illness mouse model. Life sciences. vol 279. 2021-07-05. PMID:34102195. |
lacto-n-fucopentaose-iii ameliorates acute and persisting hippocampal synaptic plasticity and transmission deficits in a gulf war illness mouse model. |
2021-07-05 |
2023-08-13 |
mouse |
| Kyle A Brown, Jessica M Carpenter, Collin J Preston, Helaina D Ludwig, Kendall B Clay, Donald A Harn, Thomas Norberg, John J Wagner, Nikolay M Filipo. Lacto-N-fucopentaose-III ameliorates acute and persisting hippocampal synaptic plasticity and transmission deficits in a Gulf War Illness mouse model. Life sciences. vol 279. 2021-07-05. PMID:34102195. |
the present study investigated if treatment with the immunotherapeutic, lacto-n-fucopentaose-iii (lnfpiii), resulted in amelioration of acute and persisting deficits in synaptic plasticity and transmission as well as trophic factor expression along the hippocampal dorsoventral axis in a mouse model of gulf war illness (gwi). |
2021-07-05 |
2023-08-13 |
mouse |
| Hyungju Park, Kyung-Seok Han, Jinsoo Seo, Jaekwang Lee, Shashank M Dravid, Junsung Woo, Heejung Chun, Sukhee Cho, Jin Young Bae, Heeyoung An, Woohyun Koh, Bo-Eun Yoon, Rolando Berlinguer-Palmini, Guido Mannaioni, Stephen F Traynelis, Yong Chul Bae, Se-Young Choi, C Justin Le. Correction to: Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors. Molecular brain. vol 14. issue 1. 2021-07-03. PMID:34187529. |
correction to: channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic nmda receptors. |
2021-07-03 |
2023-08-13 |
Not clear |
| Maximilian Lenz, Amelie Eichler, Pia Kruse, Andreas Strehl, Silvia Rodriguez-Rozada, Itamar Goren, Nir Yogev, Stefan Frank, Ari Waisman, Thomas Deller, Steffen Jung, Nicola Maggio, Andreas Vlacho. Interleukin 10 Restores Lipopolysaccharide-Induced Alterations in Synaptic Plasticity Probed by Repetitive Magnetic Stimulation. Frontiers in immunology. vol 11. 2021-07-02. PMID:33391287. |
in previous work, we demonstrated that bacterial lipopolysaccharide (lps)-induced systemic inflammation alters the ability of hippocampal neurons to express synaptic plasticity, i.e., the long-term potentiation (ltp) of excitatory neurotransmission. |
2021-07-02 |
2023-08-13 |
mouse |