| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dan-Dan Tian, Min Wang, An Liu, Mei-Rong Gao, Chen Qiu, Wen Yu, Wen-Ju Wang, Kun Zhang, Le Yang, Yan-Yan Jia, Chang-Bin Yang, Yu-Mei W. Antidepressant Effect of Paeoniflorin Is Through Inhibiting Pyroptosis CASP-11/GSDMD Pathway. Molecular neurobiology. vol 58. issue 2. 2021-09-01. PMID:33025508. |
here, we provide evidence that paeoniflorin (pf), a monoterpene glycoside compound derived from paeonia lactiflora, ameliorated reserpine-induced mouse depression-like behaviors, characterized as increased mobility time in tail suspension test and forced swimming test, as well as the abnormal alteration of synaptic plasticity in the depressive hippocampus. |
2021-09-01 |
2023-08-13 |
mouse |
| Jian Hu, Ce Li, Yan Hua, Peile Liu, Beiyao Gao, Yuyuan Wang, Yulong Ba. Constraint-induced movement therapy improves functional recovery after ischemic stroke and its impacts on synaptic plasticity in sensorimotor cortex and hippocampus. Brain research bulletin. vol 160. 2021-08-31. PMID:32298779. |
constraint-induced movement therapy improves functional recovery after ischemic stroke and its impacts on synaptic plasticity in sensorimotor cortex and hippocampus. |
2021-08-31 |
2023-08-13 |
human |
| N M Weston, A T Rolfe, A H Freelin, T M Reeves, D Su. Traumatic brain injury modifies synaptic plasticity in newly-generated granule cells of the adult hippocampus. Experimental neurology. vol 336. 2021-08-30. PMID:33188818. |
traumatic brain injury modifies synaptic plasticity in newly-generated granule cells of the adult hippocampus. |
2021-08-30 |
2023-08-13 |
rat |
| Katherine E Squires, Kyle J Gerber, Matthew C Tillman, Daniel J Lustberg, Carolina Montañez-Miranda, Meilan Zhao, Suneela Ramineni, Christopher D Scharer, Ramendra N Saha, Feng-Jue Shu, Jason P Schroeder, Eric A Ortlund, David Weinshenker, Serena M Dudek, John R Heple. Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. The Journal of biological chemistry. vol 296. 2021-08-27. PMID:33410399. |
rgs14 is a multifunctional signaling protein that suppresses synaptic plasticity in dendritic spines of hippocampal neurons. |
2021-08-27 |
2023-08-13 |
mouse |
| Katherine E Squires, Kyle J Gerber, Matthew C Tillman, Daniel J Lustberg, Carolina Montañez-Miranda, Meilan Zhao, Suneela Ramineni, Christopher D Scharer, Ramendra N Saha, Feng-Jue Shu, Jason P Schroeder, Eric A Ortlund, David Weinshenker, Serena M Dudek, John R Heple. Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. The Journal of biological chemistry. vol 296. 2021-08-27. PMID:33410399. |
when introduced into mice by crispr/cas9, rgs14-lr protein expression was detected predominantly in the nuclei of neurons within hippocampus, central amygdala, piriform cortex, and striatum, brain regions associated with learning and synaptic plasticity. |
2021-08-27 |
2023-08-13 |
mouse |
| Alice Shaam Al Abed, Azza Sellami, Mylene Potier, Eva-Gunnel Ducourneau, Pauline Gerbeaud-Lassau, Laurent Brayda-Bruno, Valerie Lamothe, Nathalie Sans, Aline Desmedt, Peter Vanhoutte, Catherine Bennetau-Pelissero, Pierre Trifilieff, Aline Marighett. Age-related impairment of declarative memory: linking memorization of temporal associations to GluN2B redistribution in dorsal CA1. Aging cell. vol 19. issue 10. 2021-08-26. PMID:33009891. |
they are indeed considered as crucial for hippocampal synaptic plasticity and hippocampus-dependent memory formation, which are both altered in aging. |
2021-08-26 |
2023-08-13 |
Not clear |
| Joseph T Schmalz, Gautam Kuma. A computational model of dopaminergic modulation of hippocampal Schaffer collateral-CA1 long-term plasticity. Journal of computational neuroscience. 2021-08-25. PMID:34431067. |
dopamine plays a critical role in modulating the long-term synaptic plasticity of the hippocampal schaffer collateral-ca1 pyramidal neuron synapses (sc-ca1), a widely accepted cellular model of learning and memory. |
2021-08-25 |
2023-08-13 |
Not clear |
| Alexander V Maltsev, Pavel M Balaba. PP1/PP2A phosphatase inhibition-induced metaplasticity in protein synthesis blocker-treated hippocampal slices: LTP and LTD, or There and Back again. Biochemical and biophysical research communications. vol 558. 2021-08-23. PMID:33901925. |
long-term potentiation (ltp) and long-term depression (ltd) are key forms of synaptic plasticity in the hippocampus. |
2021-08-23 |
2023-08-13 |
Not clear |
| Athina Miliou, Vassilis Papaleonidopoulos, George Trompoukis, Costas Papatheodoropoulo. Septotemporal variation in beta-adrenergic modulation of short-term dynamics in the hippocampus. IBRO neuroscience reports. vol 11. 2021-08-20. PMID:34409401. |
recent evidence shows a greater facilitating effect of beta-adrenergic receptors (β-ars) on long-term synaptic plasticity in the ventral versus the dorsal hippocampus. |
2021-08-20 |
2023-08-13 |
Not clear |
| Athina Miliou, Vassilis Papaleonidopoulos, George Trompoukis, Costas Papatheodoropoulo. Septotemporal variation in beta-adrenergic modulation of short-term dynamics in the hippocampus. IBRO neuroscience reports. vol 11. 2021-08-20. PMID:34409401. |
here, using field potentials from the ca1 area and a ten-pulse stimulation train of varying frequency we show that activation of β-ars by isoproterenol preferentially facilitates the output from the dorsal hippocampus at the frequency range of 3-40 hz without affecting short-term synaptic plasticity. |
2021-08-20 |
2023-08-13 |
Not clear |
| L Stan Leung, Clayton S H La. Phasic modulation of hippocampal synaptic plasticity by theta rhythm. Behavioral neuroscience. vol 134. issue 6. 2021-08-19. PMID:31916794. |
phasic modulation of hippocampal synaptic plasticity by theta rhythm. |
2021-08-19 |
2023-08-13 |
human |
| Nicola Brandt, Ricardo Vierk, Lars Fester, Max Anstötz, Lepu Zhou, Lukas F Heilmann, Simon Kind, Paul Steffen, Gabriele M Run. Sex-specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 4. 2021-08-18. PMID:31800024. |
sex-specific difference of hippocampal synaptic plasticity in response to sex neurosteroids. |
2021-08-18 |
2023-08-13 |
Not clear |
| Nicola Brandt, Ricardo Vierk, Lars Fester, Max Anstötz, Lepu Zhou, Lukas F Heilmann, Simon Kind, Paul Steffen, Gabriele M Run. Sex-specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 4. 2021-08-18. PMID:31800024. |
in this study, we address the question as to whether actions of neurosteroids, thus steroids, which are synthesized and function within the brain, contribute to sex-specific hippocampal synaptic plasticity. |
2021-08-18 |
2023-08-13 |
Not clear |
| Lara Costa, Alessandra Tempio, Enza Lacivita, Marcello Leopoldo, Lucia Cirann. Serotonin 5-HT7 receptors require cyclin-dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome. The European journal of neuroscience. 2021-08-18. PMID:33949019. |
serotonin 5-ht7 receptors require cyclin-dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of fragile x syndrome. |
2021-08-18 |
2023-08-13 |
mouse |
| Lara Costa, Alessandra Tempio, Enza Lacivita, Marcello Leopoldo, Lucia Cirann. Serotonin 5-HT7 receptors require cyclin-dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome. The European journal of neuroscience. 2021-08-18. PMID:33949019. |
electrophysiology studies in fmr1 knockout (ko) mice, a murine model of fragile x syndrome, have demonstrated alterations of synaptic plasticity, with exaggerated long-term depression induced by activation of metabotropic glutamate receptors (mglur-ltd) in fmr1 ko hippocampus. |
2021-08-18 |
2023-08-13 |
mouse |
| Lara Costa, Alessandra Tempio, Enza Lacivita, Marcello Leopoldo, Lucia Cirann. Serotonin 5-HT7 receptors require cyclin-dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome. The European journal of neuroscience. 2021-08-18. PMID:33949019. |
here we show that pharmacological inhibition of cyclin-dependent kinase 5 (cdk5, a signaling molecule recently shown to be a modulator of brain synaptic plasticity) enhanced mglur-ltd in wild-type hippocampal neurons, which became comparable to exaggerated mglur-ltd observed in fmr1 ko neurons. |
2021-08-18 |
2023-08-13 |
mouse |
| Lara Costa, Alessandra Tempio, Enza Lacivita, Marcello Leopoldo, Lucia Cirann. Serotonin 5-HT7 receptors require cyclin-dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome. The European journal of neuroscience. 2021-08-18. PMID:33949019. |
our results show that cdk5 modulates hippocampal synaptic plasticity. |
2021-08-18 |
2023-08-13 |
mouse |
| De-Huang Guo, Masaki Yamamoto, Caterina M Hernandez, Hesam Khodadadi, Babak Baban, Alexis M Stranaha. Beige adipocytes mediate the neuroprotective and anti-inflammatory effects of subcutaneous fat in obese mice. Nature communications. vol 12. issue 1. 2021-08-17. PMID:34330904. |
beige adipocytes restore hippocampal synaptic plasticity following transplantation, and these effects require the anti-inflammatory cytokine interleukin-4 (il4). |
2021-08-17 |
2023-08-13 |
mouse |
| Pierre Sauton, Chloé Deschamps, Virginie Jeanblanc, Olivier Pierrefiche, Jérôme Jeanblanc, Mickael Naassil. Interstrain differences in voluntary binge-like drinking behavior and in two acute ethanol injections-induced synaptic plasticity deficits in rats. Addiction biology. vol 26. issue 4. 2021-08-16. PMID:33331070. |
because we found different propensity to bd between strains, we also sought to test interstrain differences using another procedure of two acute ethanol exposures known to alter long-term depression of hippocampal synaptic plasticity. |
2021-08-16 |
2023-08-13 |
rat |
| Pierre Sauton, Chloé Deschamps, Virginie Jeanblanc, Olivier Pierrefiche, Jérôme Jeanblanc, Mickael Naassil. Interstrain differences in voluntary binge-like drinking behavior and in two acute ethanol injections-induced synaptic plasticity deficits in rats. Addiction biology. vol 26. issue 4. 2021-08-16. PMID:33331070. |
in addition, with the other paradigm of forced acute ethanol exposure, the long-evans strain displayed an increase in sensitivity to the deleterious effect of bd on hippocampal synaptic plasticity. |
2021-08-16 |
2023-08-13 |
rat |