| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenhui Qu, Kiall F Suazo, Wenfeng Liu, Shaowu Cheng, Angela Jeong, David Hottman, Li-Lian Yuan, Mark D Distefano, Ling L. Neuronal Protein Farnesylation Regulates Hippocampal Synaptic Plasticity and Cognitive Function. Molecular neurobiology. vol 58. issue 3. 2021-10-13. PMID:33098528. |
however, forebrain neuron-specific ft deletion also leads to reduced synaptic plasticity, memory retention, and hippocampal dendritic spine density. |
2021-10-13 |
2023-08-13 |
mouse |
| Machhindra Garad, Elke Edelmann, Volkmar Leßman. Long-term depression at hippocampal mossy fiber-CA3 synapses involves BDNF but is not mediated by p75NTR signaling. Scientific reports. vol 11. issue 1. 2021-10-13. PMID:33879805. |
while most experimental evidence for this bdnf dependence of synaptic plasticity in the hippocampus was derived from schaffer collateral (sc)-ca1 synapses, much less is known about the mechanisms of synaptic plasticity, in particular ltd, at hippocampal mossy fiber (mf) synapses onto ca3 neurons. |
2021-10-13 |
2023-08-13 |
Not clear |
| Ji-Hong Liu, Meng Zhang, Qian Wang, Ding-Yu Wu, Wei Jie, Neng-Yuan Hu, Jia-Zhuo Lan, Kai Zeng, Shu-Ji Li, Xiao-Wen Li, Jian-Ming Yang, Tian-Ming Ga. Distinct roles of astroglia and neurons in synaptic plasticity and memory. Molecular psychiatry. 2021-10-13. PMID:34642458. |
long-term potentiation (ltp) in the hippocampus is the most studied form of synaptic plasticity. |
2021-10-13 |
2023-08-13 |
Not clear |
| Yasunori Takahashi, Risako Yamashita, Hiromu Okano, Kazumi Takashima, Bunichiro Ogawa, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Gye-Hyeong Woo, Toshinori Yoshida, Makoto Shibutan. Aberrant neurogenesis and late onset suppression of synaptic plasticity as well as sustained neuroinflammation in the hippocampal dentate gyrus after developmental exposure to ethanol in rats. Toxicology. vol 462. 2021-10-11. PMID:34547370. |
aberrant neurogenesis and late onset suppression of synaptic plasticity as well as sustained neuroinflammation in the hippocampal dentate gyrus after developmental exposure to ethanol in rats. |
2021-10-11 |
2023-08-13 |
rat |
| Megan A Johnson, Natalina H Contoreggi, Joshua F Kogan, Matthew Bryson, Batsheva R Rubin, Jason D Gray, Mary Jeanne Kreek, Bruce S McEwen, Teresa A Milne. Chronic stress differentially alters mRNA expression of opioid peptides and receptors in the dorsal hippocampus of female and male rats. The Journal of comparative neurology. vol 529. issue 10. 2021-10-08. PMID:33483980. |
the sex-specific changes in hippocampal opioid gene expression may impact network properties and synaptic plasticity processes that may contribute to the attenuation of oxycodone cpp in cis males. |
2021-10-08 |
2023-08-13 |
rat |
| Erika Meyer, Jéssica Mendes Bonato, Marco Aurélio Mori, Bianca Andretto Mattos, Francisco Silveira Guimarães, Humberto Milani, Alline Cristina de Campos, Rúbia Maria Weffort de Oliveir. Cannabidiol Confers Neuroprotection in Rats in a Model of Transient Global Cerebral Ischemia: Impact of Hippocampal Synaptic Neuroplasticity. Molecular neurobiology. vol 58. issue 10. 2021-10-08. PMID:34302281. |
hippocampal synaptic plasticity is a fundamental mechanism of learning and memory. |
2021-10-08 |
2023-08-13 |
rat |
| Erika Meyer, Jéssica Mendes Bonato, Marco Aurélio Mori, Bianca Andretto Mattos, Francisco Silveira Guimarães, Humberto Milani, Alline Cristina de Campos, Rúbia Maria Weffort de Oliveir. Cannabidiol Confers Neuroprotection in Rats in a Model of Transient Global Cerebral Ischemia: Impact of Hippocampal Synaptic Neuroplasticity. Molecular neurobiology. vol 58. issue 10. 2021-10-08. PMID:34302281. |
these results suggest that the neuroprotective effects of cbd against tgci-induced memory impairments involve changes in synaptic plasticity in the hippocampus. |
2021-10-08 |
2023-08-13 |
rat |
| Rafael Roesler, Marise B Parent, Ryan T LaLumiere, Christa K McIntyr. Amygdala-hippocampal interactions in synaptic plasticity and memory formation. Neurobiology of learning and memory. vol 184. 2021-10-08. PMID:34302951. |
findings indicate that the bla influences hippocampal-dependent memories, as well as synaptic plasticity, histone modifications, gene expression, and translation of synaptic plasticity associated proteins in the hippocampus. |
2021-10-08 |
2023-08-13 |
Not clear |
| Jie Wan, Chu-Meng Shen, Yu Wang, Qing-Zi Wu, Yi-Lei Wang, Qiang Liu, Yi-Man Sun, Jun-Ping Cao, Yu-Qing W. Repeated exposure to propofol in the neonatal period impairs hippocampal synaptic plasticity and the recognition function of rats in adulthood. Brain research bulletin. vol 169. 2021-10-07. PMID:33450329. |
repeated exposure to propofol in the neonatal period impairs hippocampal synaptic plasticity and the recognition function of rats in adulthood. |
2021-10-07 |
2023-08-13 |
rat |
| Jie Wan, Chu-Meng Shen, Yu Wang, Qing-Zi Wu, Yi-Lei Wang, Qiang Liu, Yi-Man Sun, Jun-Ping Cao, Yu-Qing W. Repeated exposure to propofol in the neonatal period impairs hippocampal synaptic plasticity and the recognition function of rats in adulthood. Brain research bulletin. vol 169. 2021-10-07. PMID:33450329. |
all of the results above indicate that repeated exposure to propofol in the neonatal period can impair hippocampal synaptic plasticity and the recognition function of rats in adulthood. |
2021-10-07 |
2023-08-13 |
rat |
| Ze Yang, Xi Xiao, Runwen Chen, Xinxin Xu, Wanzeng Kong, Tao Zhan. Disc1 gene down-regulation impaired synaptic plasticity and recognition memory via disrupting neural activity in mice. Brain research bulletin. vol 171. 2021-10-07. PMID:33745948. |
altogether, our findings suggest that the abnormal pattern of neural activities in the hippocampus network disrupts information processing and finally leads to the impairments of synaptic plasticity and recognition in disc1 knockdown mice, which are possibly associated with the obstruction of neurotransmitter transmission. |
2021-10-07 |
2023-08-13 |
mouse |
| Sina Khajei, Javad Mirnajafi-Zadeh, Vahid Sheibani, Meysam Ahmadi-Zeidabadi, Yaser Masoumi-Ardakani, Mohammad Amin Rajizadeh, Khadijeh Esmaeilpou. Electromagnetic field protects against cognitive and synaptic plasticity impairment induced by electrical kindling in rats. Brain research bulletin. vol 171. 2021-10-07. PMID:33753209. |
in the current study, the effects of emf on learning and memory, as well as hippocampal synaptic plasticity, in kindled rats were investigated. |
2021-10-07 |
2023-08-13 |
rat |
| Júnia L de Deus, Mateus R Amorim, Aline B Ribeiro, Procópio C G Barcellos-Filho, César C Ceballos, Luiz Guilherme S Branco, Alexandra O S Cunha, Ricardo M Leã. Loss of Brain-Derived Neurotrophic Factor Mediates Inhibition of Hippocampal Long-Term Potentiation by High-Intensity Sound. Cellular and molecular neurobiology. vol 41. issue 4. 2021-10-06. PMID:32445041. |
although sound stimulation did not affect glutamatergic or gabaergic neurotransmission in ca1, it did depress the level of brain-derived neurotrophic factor (bdnf), which is involved in promoting hippocampal synaptic plasticity. |
2021-10-06 |
2023-08-13 |
rat |
| Sandra Sánchez-Sarasúa, Alberto Ribes-Navarro, María Teresa Beltrán-Bretones, Ana María Sánchez-Pére. AAV delivery of shRNA against IRS1 in GABAergic neurons in rat hippocampus impairs spatial memory in females and male rats. Brain structure & function. vol 226. issue 1. 2021-10-05. PMID:33245394. |
these results support that, small alterations in the insulin/igf1 pathway in specific hippocampal circuitries can underlie alterations in synaptic plasticity and affect behavior, in the absence of inflammatory conditions. |
2021-10-05 |
2023-08-13 |
human |
| b' Mar\\xc3\\xada Villafranca-Faus, Manuel Esteban Vila-Mart\\xc3\\xadn, Daniel Esteve, Esteban Merino, Anna Teruel-Sanchis, Ana Cervera-Ferri, Joana Mart\\xc3\\xadnez-Ric\\xc3\\xb3s, Ana Lloret, Enrique Lanuza, Vicent Teruel-Mart\\xc3\\xa. Integrating pheromonal and spatial information in the amygdalo-hippocampal network. Nature communications. vol 12. issue 1. 2021-10-05. PMID:34489431.' |
the detection of urine stimuli induces synaptic plasticity in the vomeronasal pathway and the dorsal hippocampus, even in animals with experimentally induced anosmia. |
2021-10-05 |
2023-08-13 |
mouse |
| Yu-Ju Chen, Shin-Meng Deng, Hui-Wen Chen, Chi-Hui Tsao, Wei-Ting Chen, Sin-Jhong Cheng, Hsien-Sung Huang, Bertrand Chin-Ming Tan, Martin M Matzuk, Jonathan Flint, Guo-Jen Huan. Follistatin mediates learning and synaptic plasticity via regulation of Asic4 expression in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 39. 2021-10-05. PMID:34544873. |
follistatin mediates learning and synaptic plasticity via regulation of asic4 expression in the hippocampus. |
2021-10-05 |
2023-08-13 |
Not clear |
| Theresa Wiesner, Anthony Bilodeau, Renaud Bernatchez, Andréanne Deschênes, Bastian Raulier, Paul De Koninck, Flavie Lavoie-Cardina. Activity-Dependent Remodeling of Synaptic Protein Organization Revealed by High Throughput Analysis of STED Nanoscopy Images. Frontiers in neural circuits. vol 14. 2021-10-04. PMID:33177994. |
to characterize changes in the organization of synaptic nanodomains during synaptic plasticity over a large population of synapses, we combined stimulated emission depletion (sted) nanoscopy with a python-based statistical object distance analysis (pysoda), in dissociated cultured hippocampal circuits exposed to treatments driving different forms of synaptic plasticity. |
2021-10-04 |
2023-08-13 |
Not clear |
| Blanca Marin Bosch, Aurélien Bringard, Maria G Logrieco, Estelle Lauer, Nathalie Imobersteg, Aurélien Thomas, Guido Ferretti, Sophie Schwartz, Kinga Iglo. A single session of moderate intensity exercise influences memory, endocannabinoids and brain derived neurotrophic factor levels in men. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34257382. |
regular physical exercise enhances memory functions, synaptic plasticity in the hippocampus, and brain derived neurotrophic factor (bdnf) levels. |
2021-10-04 |
2023-08-13 |
human |
| Patricia Soriano Roque, Mehdi Hooshmandi, Laura Neagu-Lund, Shelly Yin, Noosha Yousefpour, Hiroaki Sato, Tamaki Sato, Yosuke Nakadate, Akiko Kawakami, Soroush Tahmasebi, Alfredo Ribeiro-da-Silva, Christos G Gkogkas, Masha Prager-Khoutorsky, Thomas Schricker, Linda Wykes, Arkady Khoutorsk. Intranasal insulin rescues repeated anesthesia-induced deficits in synaptic plasticity and memory and prevents apoptosis in neonatal mice via mTORC1. Scientific reports. vol 11. issue 1. 2021-10-04. PMID:34326413. |
our study demonstrates that intranasal insulin prevents general anesthesia-induced apoptosis of hippocampal cells, and deficits in synaptic plasticity and memory, and suggests that the rescue effect is mediated via mtorc1/4e-bp2 signaling. |
2021-10-04 |
2023-08-13 |
mouse |
| A H Alhowail, M Aldubaya. Recent progress in the elucidation of the mechanisms of chemotherapy-induced cognitive impairment. European review for medical and pharmacological sciences. vol 25. issue 18. 2021-10-04. PMID:34604972. |
according to the reviewed studies, the mechanisms by which chemotherapy could cause chemobrain include disruption of hippocampal cell proliferation and neurogenesis, hormonal changes, increased oxidative stress and reactive oxygen species production, chronic increase in inflammation, and alterations in synaptic plasticity and long-term potentiation. |
2021-10-04 |
2023-08-13 |
Not clear |