| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nasrin Hashemi-Firouzi, Siamak Shahidi, Sara Soleimani As. Chronic stimulation of the serotonergic 5-HT4 receptor modulates amyloid-beta-related impairments in synaptic plasticity and memory deficits in male rats. Brain research. vol 1773. 2021-11-12. PMID:34695393. |
hippocampal synaptic plasticity was evaluated in the dentate gyrus (dg) in response to the stimulation applied to the perforant pathway. |
2021-11-12 |
2023-08-13 |
rat |
| Sara Chavoshinezhad, Mohammad Ismail Zibaii, Mir Hossein Seyed Nazari, Abdolaziz Ronaghi, Afsaneh Asgari Taei, Ahmad Ghorbani, Sareh Pandamooz, Mohammad Saied Salehi, Neda Valian, Fereshteh Motamedi, Abbas Haghparast, Leila Dargah. Optogenetic stimulation of entorhinal cortex reveals the implication of insulin signaling in adult rat's hippocampal neurogenesis. Progress in neuro-psychopharmacology & biological psychiatry. vol 111. 2021-11-11. PMID:33964323. |
here, by means of an optogenetic approach, we investigated neurogenesis and synaptic plasticity in the hippocampus of adult rats induced by stimulation of the perforant pathway. |
2021-11-11 |
2023-08-13 |
rat |
| Sara Chavoshinezhad, Mohammad Ismail Zibaii, Mir Hossein Seyed Nazari, Abdolaziz Ronaghi, Afsaneh Asgari Taei, Ahmad Ghorbani, Sareh Pandamooz, Mohammad Saied Salehi, Neda Valian, Fereshteh Motamedi, Abbas Haghparast, Leila Dargah. Optogenetic stimulation of entorhinal cortex reveals the implication of insulin signaling in adult rat's hippocampal neurogenesis. Progress in neuro-psychopharmacology & biological psychiatry. vol 111. 2021-11-11. PMID:33964323. |
the expression of synaptic plasticity and neurogenesis markers in the hippocampus were evaluated using molecular and histological approaches. |
2021-11-11 |
2023-08-13 |
rat |
| Sara Chavoshinezhad, Mohammad Ismail Zibaii, Mir Hossein Seyed Nazari, Abdolaziz Ronaghi, Afsaneh Asgari Taei, Ahmad Ghorbani, Sareh Pandamooz, Mohammad Saied Salehi, Neda Valian, Fereshteh Motamedi, Abbas Haghparast, Leila Dargah. Optogenetic stimulation of entorhinal cortex reveals the implication of insulin signaling in adult rat's hippocampal neurogenesis. Progress in neuro-psychopharmacology & biological psychiatry. vol 111. 2021-11-11. PMID:33964323. |
our results showed that optogenetic stimulation of the entorhinal cortex promotes hippocampal neurogenesis and synaptic plasticity concomitant with the increased levels of insulin mrna and its signaling markers, neurotrophic factors, and activation of mitochondrial biogenesis. |
2021-11-11 |
2023-08-13 |
rat |
| Maria Rosaria Tropea, Domenica D Li Puma, Marcello Melone, Walter Gulisano, Ottavio Arancio, Claudio Grassi, Fiorenzo Conti, Daniela Puzz. Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology. Progress in neurobiology. vol 206. 2021-11-11. PMID:34453977. |
we found that α7nachr deletion caused an impairment of hippocampal synaptic plasticity and memory at 12 months of age, paralleled by an increase of amyloid precursor protein expression and aβ levels. |
2021-11-11 |
2023-08-13 |
mouse |
| Yong Liu, Supeng Ding, Yifei Luan, Zhichao Zhu, Yuting Cai, Yingkui Li. Ginkgo biloba extracts inhibit post-ischemic LTP through attenuating EPSCs in rat hippocampus. Metabolic brain disease. vol 36. issue 8. 2021-11-11. PMID:34463942. |
in this article, effects of egb761 and its monomer component ginkgolide a (ga), ginkgolide b (gb), ginkgolide c (gc) and quercetin on rat hippocampal synaptic plasticity were studied. |
2021-11-11 |
2023-08-13 |
rat |
| Kelly E Carstens, Daniel J Lustberg, Emma K Shaughnessy, Katharine E McCann, Georgia M Alexander, Serena M Dude. Perineuronal net degradation rescues CA2 plasticity in a mouse model of Rett syndrome. The Journal of clinical investigation. vol 131. issue 16. 2021-11-08. PMID:34228646. |
we previously reported that pnns function to restrict synaptic plasticity in hippocampal area ca2, which is unusually resistant to long-term potentiation (ltp) and has been linked to social learning in mice. |
2021-11-08 |
2023-08-13 |
mouse |
| Samaneh Safari, Nesa Ahmadi, Reihaneh Mohammadkhani, Reza Ghahremani, Maryam Khajvand-Abedeni, Siamak Shahidi, Alireza Komaki, Iraj Salehi, Seyed Asaad Karim. Sex differences in spatial learning and memory and hippocampal long-term potentiation at perforant pathway-dentate gyrus (PP-DG) synapses in Wistar rats. Behavioral and brain functions : BBF. vol 17. issue 1. 2021-11-05. PMID:34724971. |
moreover, to assess sex difference in hippocampal synaptic plasticity we examined hippocampal long-term potentiation (ltp) at perforant pathway-dentate gyrus (pp-dg) synapses. |
2021-11-05 |
2023-08-13 |
rat |
| Yujun Guo, Guichang Zou, Keke Qi, Jin Jin, Lei Yao, Yang Pan, Wei Xion. Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice. Molecular brain. vol 14. issue 1. 2021-11-04. PMID:33627175. |
simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice. |
2021-11-04 |
2023-08-13 |
mouse |
| Yujun Guo, Guichang Zou, Keke Qi, Jin Jin, Lei Yao, Yang Pan, Wei Xion. Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice. Molecular brain. vol 14. issue 1. 2021-11-04. PMID:33627175. |
however, whether these statins can affect cholesterol levels and synaptic plasticity in hippocampus and the in vivo consequence remain unclear. |
2021-11-04 |
2023-08-13 |
mouse |
| Yujun Guo, Guichang Zou, Keke Qi, Jin Jin, Lei Yao, Yang Pan, Wei Xion. Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice. Molecular brain. vol 14. issue 1. 2021-11-04. PMID:33627175. |
here, we report that long-term subcutaneous treatments of simvastatin significantly impair mouse hippocampal synaptic plasticity, reflected by the attenuated long-term potentiation of field excitatory postsynaptic potentials. |
2021-11-04 |
2023-08-13 |
mouse |
| Yujun Guo, Guichang Zou, Keke Qi, Jin Jin, Lei Yao, Yang Pan, Wei Xion. Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice. Molecular brain. vol 14. issue 1. 2021-11-04. PMID:33627175. |
such effects of simvastatin are transient because drug discontinuation can restore the hippocampal cholesterol level and synaptic plasticity and the memory function. |
2021-11-04 |
2023-08-13 |
mouse |
| Wenxin Zhang, Xueqing Chai, Xiaolin Li, Xiaoyue Tan, Zhuo Yan. Legumain knockout improves repeated corticosterone injection-induced depression-like emotional and cognitive deficits. Behavioural brain research. vol 413. 2021-11-04. PMID:34265317. |
in conclusion, our results demonstrated that legumain knockout up-regulated expression of the gr by reducing protein expression in the mapk signaling pathway, thereby improving hippocampal synaptic plasticity as well as the emotional and cognitive impairment of model mice. |
2021-11-04 |
2023-08-13 |
mouse |
| Cheng-Che Lee, De-Yu Wu, Syue-Yi Chen, Yi-Pin Lin, Tsung-Ming Le. Exercise intensities modulate cognitive function in spontaneously hypertensive rats through oxidative mediated synaptic plasticity in hippocampus. Journal of cellular and molecular medicine. vol 25. issue 17. 2021-11-04. PMID:34328702. |
exercise intensities modulate cognitive function in spontaneously hypertensive rats through oxidative mediated synaptic plasticity in hippocampus. |
2021-11-04 |
2023-08-13 |
rat |
| Marco Capogna, Pablo E Castillo, Arianna Maffe. The ins and outs of inhibitory synaptic plasticity: Neuron types, molecular mechanisms and functional roles. The European journal of neuroscience. vol 54. issue 8. 2021-11-03. PMID:32663353. |
here, we provide an updated overview of inhibitory synaptic plasticity with a focus on the hippocampus and neocortex. |
2021-11-03 |
2023-08-13 |
Not clear |
| A A Keiser, E A Kramár, T Dong, S Shanur, M Pirodan, N Ru, M M Acharya, J E Baulch, C L Limoli, M A Woo. Systemic HDAC3 inhibition ameliorates impairments in synaptic plasticity caused by simulated galactic cosmic radiation exposure in male mice. Neurobiology of learning and memory. vol 178. 2021-11-02. PMID:33359392. |
here, we examined whether whole body exposure to simulated gcr using 6 ions and doses of 5 or 30 cgy interfered with the ability to update an existing memory or impact hippocampal synaptic plasticity, a cellular mechanism believed to underlie memory processes, by examining long term potentiation (ltp) in acute hippocampal slices from middle aged male mice 3.5-5 months after radiation exposure. |
2021-11-02 |
2023-08-13 |
mouse |
| Saltuk Bugra Baltaci, Omer Unal, Elif Gulbahce-Mutlu, Haluk Gumus, Suray Pehlivanoglu, Ahmet Yardimci, Rasim Mogulkoc, Abdulkerim Kasim Baltac. The Role of Zinc Status on Spatial Memory, Hippocampal Synaptic Plasticity, and Insulin Signaling in icv-STZ-Induced Sporadic Alzheimer's-Like Disease in Rats. Biological trace element research. 2021-11-02. PMID:34727320. |
the role of zinc status on spatial memory, hippocampal synaptic plasticity, and insulin signaling in icv-stz-induced sporadic alzheimer's-like disease in rats. |
2021-11-02 |
2023-08-13 |
rat |
| Saltuk Bugra Baltaci, Omer Unal, Elif Gulbahce-Mutlu, Haluk Gumus, Suray Pehlivanoglu, Ahmet Yardimci, Rasim Mogulkoc, Abdulkerim Kasim Baltac. The Role of Zinc Status on Spatial Memory, Hippocampal Synaptic Plasticity, and Insulin Signaling in icv-STZ-Induced Sporadic Alzheimer's-Like Disease in Rats. Biological trace element research. 2021-11-02. PMID:34727320. |
here, we investigated the effects of dietary zinc deficiency and supplementation on memory, hippocampal synaptic plasticity, and insulin signaling in intracerebroventricular streptozotocin (icv-stz)-induced sad in rats. |
2021-11-02 |
2023-08-13 |
rat |
| Saltuk Bugra Baltaci, Omer Unal, Elif Gulbahce-Mutlu, Haluk Gumus, Suray Pehlivanoglu, Ahmet Yardimci, Rasim Mogulkoc, Abdulkerim Kasim Baltac. The Role of Zinc Status on Spatial Memory, Hippocampal Synaptic Plasticity, and Insulin Signaling in icv-STZ-Induced Sporadic Alzheimer's-Like Disease in Rats. Biological trace element research. 2021-11-02. PMID:34727320. |
the expression of hippocampal protein and mrna levels of targets related to synaptic plasticity and insulin pathway was assessed by western blot and real-time quantitative pcr. |
2021-11-02 |
2023-08-13 |
rat |
| Saltuk Bugra Baltaci, Omer Unal, Elif Gulbahce-Mutlu, Haluk Gumus, Suray Pehlivanoglu, Ahmet Yardimci, Rasim Mogulkoc, Abdulkerim Kasim Baltac. The Role of Zinc Status on Spatial Memory, Hippocampal Synaptic Plasticity, and Insulin Signaling in icv-STZ-Induced Sporadic Alzheimer's-Like Disease in Rats. Biological trace element research. 2021-11-02. PMID:34727320. |
our data suggest that zinc supplementation improves cognitive deficits and rescues the decline in key molecular targets of synaptic plasticity and insulin signaling in hippocampus caused by icv-stz induced sad in rats. |
2021-11-02 |
2023-08-13 |
rat |