| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Latha Diwakar, Ruturaj Gowaikar, Keerthana Chithanathan, Barathan Gnanabharathi, Deepika Singh Tomar, Vijayalakshmi Ravindranat. Endothelin-1 mediated vasoconstriction leads to memory impairment and synaptic dysfunction. Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33649479. |
present study demonstrates that vasoconstriction leading to memory deficit and decline in activity dependent protein translation in hippocampus as a potential molecular mechanism impacting synaptic plasticity. |
2021-11-22 |
2023-08-13 |
mouse |
| Wei Sun, Yang Yang, Yazi Mei, Yuanhua Wu, Xiao Chen, Lei A. Prenatal cyanuric acid exposure depresses hippocampal synaptic plasticity and induces spatial learning and memory deficits. Toxicology letters. vol 354. 2021-11-22. PMID:34757177. |
prenatal cyanuric acid exposure depresses hippocampal synaptic plasticity and induces spatial learning and memory deficits. |
2021-11-22 |
2023-08-13 |
rat |
| Hannah E Frye, Yukitoshi Izumi, Alexis N Harris, Sidney B Williams, Christopher R Trousdale, Min-Yu Sun, Andrew D Sauerbeck, Terrance T Kummer, Steven Mennerick, Charles F Zorumski, Elliot C Nelson, Joseph D Dougherty, Jose A Moró. Sex Differences in the Role of CNIH3 on Spatial Memory and Synaptic Plasticity. Biological psychiatry. vol 90. issue 11. 2021-11-18. PMID:34548146. |
cnih3 is an ampa receptor (ampar) auxiliary protein prominently expressed in the dorsal hippocampus (dhpc), a region that plays a critical role in spatial memory and synaptic plasticity. |
2021-11-18 |
2023-08-13 |
Not clear |
| Kristin Metzdorf, Steffen Fricke, Maria Teresa Balia, Martin Korte, Marta Zagrebelsk. Nogo-A Modulates the Synaptic Excitation of Hippocampal Neurons in a Ca Cells. vol 10. issue 9. 2021-11-17. PMID:34571950. |
nogo-a modulates the synaptic excitation of hippocampal neurons in a ca a tight regulation of the balance between inhibitory and excitatory synaptic transmission is a prerequisite for synaptic plasticity in neuronal networks. |
2021-11-17 |
2023-08-13 |
mouse |
| Shao-Tsu Chen, Chung-Pin Hsieh, Mei-Yi Lee, Liao-Chen Chen, Chien-Min Huang, Hwei-Hsien Chen, Ming-Huan Cha. Betaine prevents and reverses the behavioral deficits and synaptic dysfunction induced by repeated ketamine exposure in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 144. 2021-11-17. PMID:34715446. |
these results demonstrated that both co-treatment and post-treatment with betaine could effectively prevent and reverse the adverse behavioral manifestations and hippocampal synaptic plasticity after repeated ketamine use, suggesting that betaine can be used as a novel adjunct therapy with ketamine for treatment-resistant depression and provide benefits for ketamine use disorders. |
2021-11-17 |
2023-08-13 |
mouse |
| Guoyuan Pan, Jingyan Cheng, Weimin Shen, Yao Lin, Anqi Zhu, Lingqin Jin, Qingfeng Xie, Mingjin Zhu, Chan Liu, Fengxia Tu, Xiang Che. Intensive treadmill training promotes cognitive recovery after cerebral ischemia-reperfusion in juvenile rats. Behavioural brain research. vol 401. 2021-11-15. PMID:33358915. |
to study the effect of treadmill training intensity on hippocampal synaptic plasticity after cerebral ischemia, a model of middle cerebral artery occlusion (mcao)/reperfusion was established in young rats to simulate childhood ischemic stroke. |
2021-11-15 |
2023-08-13 |
rat |
| Guoyuan Pan, Jingyan Cheng, Weimin Shen, Yao Lin, Anqi Zhu, Lingqin Jin, Qingfeng Xie, Mingjin Zhu, Chan Liu, Fengxia Tu, Xiang Che. Intensive treadmill training promotes cognitive recovery after cerebral ischemia-reperfusion in juvenile rats. Behavioural brain research. vol 401. 2021-11-15. PMID:33358915. |
treadmill training can provide neuroprotection by promoting hippocampal synaptic plasticity, with medium-intensity training showing the most optimal effects. |
2021-11-15 |
2023-08-13 |
rat |
| Raul Loera-Valencia, Erika Vazquez-Juarez, Alberto Muñoz, Gorka Gerenu, Marta Gómez-Galán, Maria Lindskog, Javier DeFelipe, Angel Cedazo-Minguez, Paula Merino-Serrai. High levels of 27-hydroxycholesterol results in synaptic plasticity alterations in the hippocampus. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33580102. |
high levels of 27-hydroxycholesterol results in synaptic plasticity alterations in the hippocampus. |
2021-11-15 |
2023-08-13 |
mouse |
| Omid Miry, Xiao-Lei Zhang, Linnea R Vose, Katisha R Gopaul, Galadu Subah, Juliet A Moncaster, Mark W Wojnarowicz, Andrew M Fisher, Chad A Tagge, Lee E Goldstein, Patric K Stanto. Life-long brain compensatory responses to galactic cosmic radiation exposure. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33619310. |
given the selective vulnerability of the hippocampus to neurotoxic insult and the importance of this brain region to learning and memory, we hypothesized that gcr-relevant hze exposure may induce long-term alterations in adult hippocampal neurogenesis, synaptic plasticity, and hippocampal-dependent learning and memory. |
2021-11-15 |
2023-08-13 |
mouse |
| Hengyi Fan, Wolfgang Sievert, Julian Hofmann, Selina J Keppler, Katja Steiger, Xènia Puig-Bosch, Bernhard Haller, Gerhard Rammes, Gabriele Multhof. Partial-Brain Radiation-Induced Microvascular Cognitive Impairment in Juvenile Murine Unilateral Hippocampal Synaptic Plasticity. International journal of radiation oncology, biology, physics. 2021-11-15. PMID:34619330. |
partial-brain radiation-induced microvascular cognitive impairment in juvenile murine unilateral hippocampal synaptic plasticity. |
2021-11-15 |
2023-08-13 |
mouse |
| b' D Cunha-Reis, A Caulino-Rocha, P Correia-de-S\\xc3\\xa. VIPergic neuroprotection in epileptogenesis: challenges and opportunities. Pharmacological research. vol 164. 2021-11-12. PMID:33338622.' |
in the hippocampus, a brain area implicated in learning and memory, vip released from basket cells and/or interneuron-selective interneurons controls gabaergic transmission and pyramidal cell activity influencing hippocampal-dependent synaptic plasticity (long-term potentiation and long-term depression) and cognition. |
2021-11-12 |
2023-08-13 |
Not clear |
| Aijaz Ahmad Naik, Huayu Sun, Cedric L Williams, Daniel S Weller, J Julius Zhu, Jaideep Kapu. Mechanism of seizure-induced retrograde amnesia. Progress in neurobiology. vol 200. 2021-11-12. PMID:33388373. |
spatial learning and a seizure caused cfos expression and synaptic plasticity overlapping set of neurons in the ca1 of the hippocampus. |
2021-11-12 |
2023-08-13 |
Not clear |
| Gino P Asuni, Andrew Speidell, Italo Mocchett. Neuronal apoptosis induced by morphine withdrawal is mediated by the p75 neurotrophin receptor. Journal of neurochemistry. vol 158. issue 2. 2021-11-12. PMID:33742683. |
at the same time, trkb, the receptor that is crucial for bdnf-mediated synaptic plasticity in the hippocampus, was decreased, suggesting that withdrawal alters the neurotrophin receptor environment to favor synaptic remodeling and apoptosis. |
2021-11-12 |
2023-08-13 |
mouse |
| Jin-Qiong Zhan, Chun-Nuan Chen, Si-Xian Wu, Han-Jun Wu, Ke Zou, Jian-Wen Xiong, Bo Wei, Yuan-Jian Yan. Flavonoid fisetin reverses impaired hippocampal synaptic plasticity and cognitive function by regulating the function of AMPARs in a male rat model of schizophrenia. Journal of neurochemistry. vol 158. issue 2. 2021-11-12. PMID:33882624. |
flavonoid fisetin reverses impaired hippocampal synaptic plasticity and cognitive function by regulating the function of ampars in a male rat model of schizophrenia. |
2021-11-12 |
2023-08-13 |
rat |
| Jin-Qiong Zhan, Chun-Nuan Chen, Si-Xian Wu, Han-Jun Wu, Ke Zou, Jian-Wen Xiong, Bo Wei, Yuan-Jian Yan. Flavonoid fisetin reverses impaired hippocampal synaptic plasticity and cognitive function by regulating the function of AMPARs in a male rat model of schizophrenia. Journal of neurochemistry. vol 158. issue 2. 2021-11-12. PMID:33882624. |
hippocampal synaptic plasticity was investigated by field potential recording. |
2021-11-12 |
2023-08-13 |
rat |
| Jin-Qiong Zhan, Chun-Nuan Chen, Si-Xian Wu, Han-Jun Wu, Ke Zou, Jian-Wen Xiong, Bo Wei, Yuan-Jian Yan. Flavonoid fisetin reverses impaired hippocampal synaptic plasticity and cognitive function by regulating the function of AMPARs in a male rat model of schizophrenia. Journal of neurochemistry. vol 158. issue 2. 2021-11-12. PMID:33882624. |
collectively, our findings demonstrate that fisetin treatment can reverse the deficits of hippocampal synaptic plasticity and memory in a male rat model of schizophrenia by restoring the phosphorylation and surface expression of ampar glua1 subunit, suggesting fisetin as a promising therapeutic candidate for schizophrenia-associated cognitive deficits. |
2021-11-12 |
2023-08-13 |
rat |
| Chiaki Ishii, Natsumi Shibano, Mio Yamazaki, Tomoki Arima, Yuna Kato, Yuki Ishii, Yo Shinoda, Yugo Fukazawa, Tetsushi Sadakata, Yoshitake Sano, Teiichi Furuich. CAPS1 is involved in hippocampal synaptic plasticity and hippocampus-associated learning. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:33883618. |
caps1 is involved in hippocampal synaptic plasticity and hippocampus-associated learning. |
2021-11-12 |
2023-08-13 |
mouse |
| Ying Huang, Xiangping Liao, Huaiwei Wang, Jianghong Luo, Shanquan Zhong, Ziliang Zhang, Fang Zhang, Jianping Chen, Fuhua Xi. Effects of imperatorin on apoptosis and synaptic plasticity in vascular dementia rats. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:33883654. |
collectively, our findings demonstrated that imp was effective in the treatment of 2vo-induced vd via inhibiting apoptosis of hippocampus neurons and reducing the synaptic plasticity destroy. |
2021-11-12 |
2023-08-13 |
rat |
| Vincenzo Mastrolia, Omar Al Massadi, Benoit de Pins, Jean-Antoine Giraul. Pyk2 in dorsal hippocampus plays a selective role in spatial memory and synaptic plasticity. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:34381140. |
pyk2 in dorsal hippocampus plays a selective role in spatial memory and synaptic plasticity. |
2021-11-12 |
2023-08-13 |
Not clear |
| Nasrin Hashemi-Firouzi, Siamak Shahidi, Sara Soleimani As. Chronic stimulation of the serotonergic 5-HT4 receptor modulates amyloid-beta-related impairments in synaptic plasticity and memory deficits in male rats. Brain research. vol 1773. 2021-11-12. PMID:34695393. |
alzheimer's disease (ad) is a neurodegenerative disease characterized by memory decline and impaired hippocampal synaptic plasticity. |
2021-11-12 |
2023-08-13 |
rat |