| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elahe Barfi, Ava Modirzadeh Tehrani, Mojtaba Mohammadpanah, Mahdi Eskandarian Boroujeni, Gholam Hossein Meftahi, Yousef Sadeghi, Samira Eziy, Aysan Khatmi, Mohammad Amin Abdollahifar, Zeynab Ghorbani, Abbas Aliaghae. The role of Tetrahydrocannabinol in inducing disrupted signaling cascades, hippocampal atrophy and memory defects. Journal of chemical neuroanatomy. vol 113. 2021-10-01. PMID:33689904. |
we also detected several dysregulated signaling pathways involved in synaptic plasticity as well as cell-cell interaction in the hippocampus of thc-treated rats. |
2021-10-01 |
2023-08-13 |
rat |
| Gabriele Di Cicco, Emanuela Marzano, Luisa Iacovelli, Roberta Celli, Gilles van Luijtelaar, Ferdinando Nicoletti, Richard T Ngomba, Mark J Wal. Group I metabotropic glutamate receptor-mediated long term depression is disrupted in the hippocampus of WAG/Rij rats modelling absence epilepsy. Neuropharmacology. vol 196. 2021-10-01. PMID:34197893. |
here we report that some forms of hippocampal synaptic plasticity are abnormal in symptomatic wistar albino glaxo/rijswijk (wag/rij) rats. |
2021-10-01 |
2023-08-13 |
rat |
| Gabriele Di Cicco, Emanuela Marzano, Luisa Iacovelli, Roberta Celli, Gilles van Luijtelaar, Ferdinando Nicoletti, Richard T Ngomba, Mark J Wal. Group I metabotropic glutamate receptor-mediated long term depression is disrupted in the hippocampus of WAG/Rij rats modelling absence epilepsy. Neuropharmacology. vol 196. 2021-10-01. PMID:34197893. |
these findings suggest that abnormalities in hippocampal mglu5 receptor-dependent synaptic plasticity are associated with the pathological phenotype of wag/rij rats. |
2021-10-01 |
2023-08-13 |
rat |
| Caitlin K Posillic. Three's Company: Neuroimmune activation, sex, and memory at the tripartite synapse. Brain, behavior, & immunity - health. vol 16. 2021-10-01. PMID:34589812. |
an important remaining component to this system is the conclusive evidence of sex differences in hippocampal plasticity mechanisms, hormone modulation of synaptic plasticity, functional properties of hippocampal neurons, and in neuroimmune activation. |
2021-10-01 |
2023-08-13 |
Not clear |
| Xin Zhao, Alejandro N Rondón-Ortiz, Erika P Lima, Madeline Puracchio, Ryland C Roderick, Amanda C Kentne. Therapeutic efficacy of environmental enrichment on behavioral, endocrine, and synaptic alterations in an animal model of maternal immune activation. Brain, behavior, & immunity - health. vol 3. 2021-09-29. PMID:32368757. |
within the prefrontal cortex, hippocampus, amygdala, and hypothalamus, mia and ee altered the mrna expression of several genes associated with resiliency and synaptic plasticity in both sexes. |
2021-09-29 |
2023-08-13 |
human |
| Dan Wu, Fengjuan Wu, Ren Lin, Yuan Meng, Wei Wei, Qi Sun, Lihong Ji. Impairment of learning and memory induced by perinatal exposure to BPA is associated with ERα-mediated alterations of synaptic plasticity and PKC/ERK/CREB signaling pathway in offspring rats. Brain research bulletin. vol 161. 2021-09-29. PMID:32380187. |
we aimed to investigate whether the impairment of learning and memory induced by perinatal exposure to bpa was associated with the hippocampal estrogen receptor α (erα)-mediated synaptic plasticity and pkc/erk/creb signaling pathway in different sex offspring rats. |
2021-09-29 |
2023-08-13 |
rat |
| Ekta Kumari, Kai Li, Zhuo Yang, Tao Zhan. Tacrine accelerates spatial long-term memory via improving impaired neural oscillations and modulating GAD isomers including neuro-receptors in the hippocampus of APP/PS1 AD mice. Brain research bulletin. vol 161. 2021-09-29. PMID:32473192. |
furthermore, our results implied that tacrine strongly improve the patterns of neural oscillations, and hippocampal synaptic plasticity in the 6th month old app-ps1 double transgenic ad-tac mice via changing the theta and alpha power spectra including with the improvement in theta, alpha and gamma synchronization. |
2021-09-29 |
2023-08-13 |
mouse |
| Zhen Lan, Zhaoyou Meng, Biyao Lian, Mengying Liu, Tao Sun, Huan Sun, Zhi Liu, Zhenxin Hu, Qiang Guo, Jiqiang Zhan. Hippocampal Aromatase Knockdown Aggravates Ovariectomy-Induced Spatial Memory Impairment, Aβ Accumulation and Neural Plasticity Deficiency in Adult Female Mice. Neurochemical research. vol 46. issue 5. 2021-09-27. PMID:33559105. |
in recent years, high levels of aromatase (arom), the estrogen synthase, has been localized in hippocampus; and this hippocampus-derived e2 seems to be functional in synaptic plasticity and spatial memory as ovarian e2 does. |
2021-09-27 |
2023-08-13 |
mouse |
| Jian Yu, Li Ren, Su Min, Feng Lv, Jie Luo, Ping Li, Yuxi Zhan. Inhibition of CB1 receptor alleviates electroconvulsive shock-induced memory impairment by regulating hippocampal synaptic plasticity in depressive rats. Psychiatry research. vol 300. 2021-09-27. PMID:33848965. |
inhibition of cb1 receptor alleviates electroconvulsive shock-induced memory impairment by regulating hippocampal synaptic plasticity in depressive rats. |
2021-09-27 |
2023-08-13 |
rat |
| Jian Yu, Li Ren, Su Min, Feng Lv, Jie Luo, Ping Li, Yuxi Zhan. Inhibition of CB1 receptor alleviates electroconvulsive shock-induced memory impairment by regulating hippocampal synaptic plasticity in depressive rats. Psychiatry research. vol 300. 2021-09-27. PMID:33848965. |
taken together, we identified that cb1r is involved in the ecs-induced spatial learning and memory impairment and inhibition of cb1r facilitates the recovery of memory impairment and hippocampal synaptic plasticity, without interfering with the therapeutic effects of ecs in depressed rats. |
2021-09-27 |
2023-08-13 |
rat |
| Ye Wang, Amy K Y Fu, Nancy Y I. IL-33/ST2 Signaling Regulates Synaptic Plasticity and Homeostasis in the Adult Hippocampal Circuitry. DNA and cell biology. vol 40. issue 9. 2021-09-23. PMID:34297618. |
il-33/st2 signaling regulates synaptic plasticity and homeostasis in the adult hippocampal circuitry. |
2021-09-23 |
2023-08-13 |
Not clear |
| Ye Wang, Amy K Y Fu, Nancy Y I. IL-33/ST2 Signaling Regulates Synaptic Plasticity and Homeostasis in the Adult Hippocampal Circuitry. DNA and cell biology. vol 40. issue 9. 2021-09-23. PMID:34297618. |
glial cells, including astrocytes and microglia, actively regulate hippocampal synaptic plasticity by coordinating the neuronal activity-induced synaptic changes at the circuit level. |
2021-09-23 |
2023-08-13 |
Not clear |
| Ye Wang, Amy K Y Fu, Nancy Y I. IL-33/ST2 Signaling Regulates Synaptic Plasticity and Homeostasis in the Adult Hippocampal Circuitry. DNA and cell biology. vol 40. issue 9. 2021-09-23. PMID:34297618. |
further investigations of how il-33/st2 signaling is regulated in a region-specific manner as well as its diverse functions in glia-synapse communications in the adult hippocampal circuitry will provide insights into the nature of hippocampal synaptic plasticity and homeostasis in health and disease. |
2021-09-23 |
2023-08-13 |
Not clear |
| Jin-Lan Huang, Fan Zhang, Min Su, Jiaxin Li, Wen Yi, Li-Xiang Hou, Si-Man Yang, Jin-Yuan Liu, Hao-An Zhang, Tengfei Ma, Deng-Pan W. MeCP2 prevents age-associated cognitive decline via restoring synaptic plasticity in a senescence-accelerated mouse model. Aging cell. vol 20. issue 9. 2021-09-23. PMID:34363729. |
overexpression of hippocampal mecp2 could elevate synaptic plasticity and cognitive function in samp8 mice, while knockdown of mecp2 impaired synaptic plasticity and cognitive function in senescence accelerated-resistant 1 (samr1) mice. |
2021-09-23 |
2023-08-13 |
mouse |
| Gaochun Zhu, Qian Zhu, Wei Zhang, Chen Hui, Yuwen Li, Meiyuan Yang, Shimin Pang, Yaobing Li, Guoyong Xue, Hongping Che. Mitochondrial uncoupling protein 2 is regulated through heterogeneous nuclear ribonucleoprotein K in lead exposure models. Journal of environmental science and health. Part C, Toxicology and carcinogenesis. vol 39. issue 1. 2021-09-22. PMID:33576715. |
synaptic plasticity plays an important role in learning and memory in the developing hippocampus. |
2021-09-22 |
2023-08-13 |
rat |
| Maryam Khodaverdi, Mona Rahdar, Shima Davoudi, Razieh Hajisoltani, Zohreh Tavassoli, Zahra Ghasemi, Aeen Ebrahim Amini, Narges Hosseinmardi, Gila Behzadi, Mahyar Janahmad. 5-HT7 receptor activation rescues impaired synaptic plasticity in an autistic-like rat model induced by prenatal VPA exposure. Neurobiology of learning and memory. vol 183. 2021-09-22. PMID:34015444. |
overall, these results provide for the first time, as far as we know, functional evidence for the restorative role of 5-ht7rs activation against prenatal vpa exposure induced behavioral deficits and hippocampal synaptic plasticity impairment. |
2021-09-22 |
2023-08-13 |
rat |
| Xin Peng, Jun Wang, Juan Peng, Hongqun Jiang, Kai L. Resveratrol Improves Synaptic Plasticity in Hypoxic-Ischemic Brain Injury in Neonatal Mice via Alleviating SIRT1/NF-κB Signaling-Mediated Neuroinflammation. Journal of molecular neuroscience : MN. 2021-09-22. PMID:34549339. |
in the present study, resveratrol was used to intervene in hypoxic-ischemic brain injury (hibi) mice, and the effects on hippocampal synaptic plasticity and further mechanisms were explored through performing neurobehavioral, morphological observations, golgi sliver staining, western blotting, and quantitative real-time polymerase chain reaction experiments. |
2021-09-22 |
2023-08-13 |
mouse |
| John P McCauley, Maurice A Petroccione, Lianna Y D'Brant, Gabrielle C Todd, Nurat Affinnih, Justin J Wisnoski, Shergil Zahid, Swasti Shree, Alioscka A Sousa, Rose M De Guzman, Rosanna Migliore, Alexey Brazhe, Richard D Leapman, Alexander Khmaladze, Alexey Semyanov, Damian G Zuloaga, Michele Migliore, Annalisa Scimem. Circadian Modulation of Neurons and Astrocytes Controls Synaptic Plasticity in Hippocampal Area CA1. Cell reports. vol 33. issue 2. 2021-09-21. PMID:33053337. |
circadian modulation of neurons and astrocytes controls synaptic plasticity in hippocampal area ca1. |
2021-09-21 |
2023-08-13 |
Not clear |
| Kyle A Brown, Collin J Preston, Jessica M Carpenter, Helaina D Ludwig, Thomas Norberg, Donald A Harn, Nikolay M Filipov, John J Wagne. Lacto-N-fucopentaose-III (LNFPIII) ameliorates acute aberrations in hippocampal synaptic transmission in a Gulf War Illness animal model. Brain research. vol 1766. 2021-09-21. PMID:33961896. |
gwi-related neurological impairments associated with pb-pm overexposures have been recapitulated in animal models; however, there is a paucity of studies assessing pb-pm-related aberrations in hippocampal synaptic plasticity and transmission that may underlie behavioral impairments. |
2021-09-21 |
2023-08-13 |
Not clear |
| Kyle A Brown, Collin J Preston, Jessica M Carpenter, Helaina D Ludwig, Thomas Norberg, Donald A Harn, Nikolay M Filipov, John J Wagne. Lacto-N-fucopentaose-III (LNFPIII) ameliorates acute aberrations in hippocampal synaptic transmission in a Gulf War Illness animal model. Brain research. vol 1766. 2021-09-21. PMID:33961896. |
in the present study, we assessed the efficacy of an immunomodulatory therapeutic, lacto-n-fucopentaose-iii (lnfpiii), on ameliorating acute effects of in vivo pb-pm exposure on synaptic plasticity and transmission as well as trophic factor/cytokine expression along the hippocampal dorsoventral axis. |
2021-09-21 |
2023-08-13 |
Not clear |