| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guoyuan Pan, Jingyan Cheng, Weimin Shen, Yao Lin, Anqi Zhu, Lingqin Jin, Qingfeng Xie, Mingjin Zhu, Chan Liu, Fengxia Tu, Xiang Che. Intensive treadmill training promotes cognitive recovery after cerebral ischemia-reperfusion in juvenile rats. Behavioural brain research. vol 401. 2021-11-15. PMID:33358915. |
to study the effect of treadmill training intensity on hippocampal synaptic plasticity after cerebral ischemia, a model of middle cerebral artery occlusion (mcao)/reperfusion was established in young rats to simulate childhood ischemic stroke. |
2021-11-15 |
2023-08-13 |
rat |
| Guoyuan Pan, Jingyan Cheng, Weimin Shen, Yao Lin, Anqi Zhu, Lingqin Jin, Qingfeng Xie, Mingjin Zhu, Chan Liu, Fengxia Tu, Xiang Che. Intensive treadmill training promotes cognitive recovery after cerebral ischemia-reperfusion in juvenile rats. Behavioural brain research. vol 401. 2021-11-15. PMID:33358915. |
treadmill training can provide neuroprotection by promoting hippocampal synaptic plasticity, with medium-intensity training showing the most optimal effects. |
2021-11-15 |
2023-08-13 |
rat |
| Raul Loera-Valencia, Erika Vazquez-Juarez, Alberto Muñoz, Gorka Gerenu, Marta Gómez-Galán, Maria Lindskog, Javier DeFelipe, Angel Cedazo-Minguez, Paula Merino-Serrai. High levels of 27-hydroxycholesterol results in synaptic plasticity alterations in the hippocampus. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33580102. |
high levels of 27-hydroxycholesterol results in synaptic plasticity alterations in the hippocampus. |
2021-11-15 |
2023-08-13 |
mouse |
| Omid Miry, Xiao-Lei Zhang, Linnea R Vose, Katisha R Gopaul, Galadu Subah, Juliet A Moncaster, Mark W Wojnarowicz, Andrew M Fisher, Chad A Tagge, Lee E Goldstein, Patric K Stanto. Life-long brain compensatory responses to galactic cosmic radiation exposure. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33619310. |
given the selective vulnerability of the hippocampus to neurotoxic insult and the importance of this brain region to learning and memory, we hypothesized that gcr-relevant hze exposure may induce long-term alterations in adult hippocampal neurogenesis, synaptic plasticity, and hippocampal-dependent learning and memory. |
2021-11-15 |
2023-08-13 |
mouse |
| Hengyi Fan, Wolfgang Sievert, Julian Hofmann, Selina J Keppler, Katja Steiger, Xènia Puig-Bosch, Bernhard Haller, Gerhard Rammes, Gabriele Multhof. Partial-Brain Radiation-Induced Microvascular Cognitive Impairment in Juvenile Murine Unilateral Hippocampal Synaptic Plasticity. International journal of radiation oncology, biology, physics. 2021-11-15. PMID:34619330. |
partial-brain radiation-induced microvascular cognitive impairment in juvenile murine unilateral hippocampal synaptic plasticity. |
2021-11-15 |
2023-08-13 |
mouse |
| b' D Cunha-Reis, A Caulino-Rocha, P Correia-de-S\\xc3\\xa. VIPergic neuroprotection in epileptogenesis: challenges and opportunities. Pharmacological research. vol 164. 2021-11-12. PMID:33338622.' |
in the hippocampus, a brain area implicated in learning and memory, vip released from basket cells and/or interneuron-selective interneurons controls gabaergic transmission and pyramidal cell activity influencing hippocampal-dependent synaptic plasticity (long-term potentiation and long-term depression) and cognition. |
2021-11-12 |
2023-08-13 |
Not clear |
| Aijaz Ahmad Naik, Huayu Sun, Cedric L Williams, Daniel S Weller, J Julius Zhu, Jaideep Kapu. Mechanism of seizure-induced retrograde amnesia. Progress in neurobiology. vol 200. 2021-11-12. PMID:33388373. |
spatial learning and a seizure caused cfos expression and synaptic plasticity overlapping set of neurons in the ca1 of the hippocampus. |
2021-11-12 |
2023-08-13 |
Not clear |
| Gino P Asuni, Andrew Speidell, Italo Mocchett. Neuronal apoptosis induced by morphine withdrawal is mediated by the p75 neurotrophin receptor. Journal of neurochemistry. vol 158. issue 2. 2021-11-12. PMID:33742683. |
at the same time, trkb, the receptor that is crucial for bdnf-mediated synaptic plasticity in the hippocampus, was decreased, suggesting that withdrawal alters the neurotrophin receptor environment to favor synaptic remodeling and apoptosis. |
2021-11-12 |
2023-08-13 |
mouse |
| Jin-Qiong Zhan, Chun-Nuan Chen, Si-Xian Wu, Han-Jun Wu, Ke Zou, Jian-Wen Xiong, Bo Wei, Yuan-Jian Yan. Flavonoid fisetin reverses impaired hippocampal synaptic plasticity and cognitive function by regulating the function of AMPARs in a male rat model of schizophrenia. Journal of neurochemistry. vol 158. issue 2. 2021-11-12. PMID:33882624. |
flavonoid fisetin reverses impaired hippocampal synaptic plasticity and cognitive function by regulating the function of ampars in a male rat model of schizophrenia. |
2021-11-12 |
2023-08-13 |
rat |
| Jin-Qiong Zhan, Chun-Nuan Chen, Si-Xian Wu, Han-Jun Wu, Ke Zou, Jian-Wen Xiong, Bo Wei, Yuan-Jian Yan. Flavonoid fisetin reverses impaired hippocampal synaptic plasticity and cognitive function by regulating the function of AMPARs in a male rat model of schizophrenia. Journal of neurochemistry. vol 158. issue 2. 2021-11-12. PMID:33882624. |
hippocampal synaptic plasticity was investigated by field potential recording. |
2021-11-12 |
2023-08-13 |
rat |
| Jin-Qiong Zhan, Chun-Nuan Chen, Si-Xian Wu, Han-Jun Wu, Ke Zou, Jian-Wen Xiong, Bo Wei, Yuan-Jian Yan. Flavonoid fisetin reverses impaired hippocampal synaptic plasticity and cognitive function by regulating the function of AMPARs in a male rat model of schizophrenia. Journal of neurochemistry. vol 158. issue 2. 2021-11-12. PMID:33882624. |
collectively, our findings demonstrate that fisetin treatment can reverse the deficits of hippocampal synaptic plasticity and memory in a male rat model of schizophrenia by restoring the phosphorylation and surface expression of ampar glua1 subunit, suggesting fisetin as a promising therapeutic candidate for schizophrenia-associated cognitive deficits. |
2021-11-12 |
2023-08-13 |
rat |
| Chiaki Ishii, Natsumi Shibano, Mio Yamazaki, Tomoki Arima, Yuna Kato, Yuki Ishii, Yo Shinoda, Yugo Fukazawa, Tetsushi Sadakata, Yoshitake Sano, Teiichi Furuich. CAPS1 is involved in hippocampal synaptic plasticity and hippocampus-associated learning. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:33883618. |
caps1 is involved in hippocampal synaptic plasticity and hippocampus-associated learning. |
2021-11-12 |
2023-08-13 |
mouse |
| Ying Huang, Xiangping Liao, Huaiwei Wang, Jianghong Luo, Shanquan Zhong, Ziliang Zhang, Fang Zhang, Jianping Chen, Fuhua Xi. Effects of imperatorin on apoptosis and synaptic plasticity in vascular dementia rats. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:33883654. |
collectively, our findings demonstrated that imp was effective in the treatment of 2vo-induced vd via inhibiting apoptosis of hippocampus neurons and reducing the synaptic plasticity destroy. |
2021-11-12 |
2023-08-13 |
rat |
| Vincenzo Mastrolia, Omar Al Massadi, Benoit de Pins, Jean-Antoine Giraul. Pyk2 in dorsal hippocampus plays a selective role in spatial memory and synaptic plasticity. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:34381140. |
pyk2 in dorsal hippocampus plays a selective role in spatial memory and synaptic plasticity. |
2021-11-12 |
2023-08-13 |
Not clear |
| Nasrin Hashemi-Firouzi, Siamak Shahidi, Sara Soleimani As. Chronic stimulation of the serotonergic 5-HT4 receptor modulates amyloid-beta-related impairments in synaptic plasticity and memory deficits in male rats. Brain research. vol 1773. 2021-11-12. PMID:34695393. |
alzheimer's disease (ad) is a neurodegenerative disease characterized by memory decline and impaired hippocampal synaptic plasticity. |
2021-11-12 |
2023-08-13 |
rat |
| Nasrin Hashemi-Firouzi, Siamak Shahidi, Sara Soleimani As. Chronic stimulation of the serotonergic 5-HT4 receptor modulates amyloid-beta-related impairments in synaptic plasticity and memory deficits in male rats. Brain research. vol 1773. 2021-11-12. PMID:34695393. |
hippocampal synaptic plasticity was evaluated in the dentate gyrus (dg) in response to the stimulation applied to the perforant pathway. |
2021-11-12 |
2023-08-13 |
rat |
| Sara Chavoshinezhad, Mohammad Ismail Zibaii, Mir Hossein Seyed Nazari, Abdolaziz Ronaghi, Afsaneh Asgari Taei, Ahmad Ghorbani, Sareh Pandamooz, Mohammad Saied Salehi, Neda Valian, Fereshteh Motamedi, Abbas Haghparast, Leila Dargah. Optogenetic stimulation of entorhinal cortex reveals the implication of insulin signaling in adult rat's hippocampal neurogenesis. Progress in neuro-psychopharmacology & biological psychiatry. vol 111. 2021-11-11. PMID:33964323. |
here, by means of an optogenetic approach, we investigated neurogenesis and synaptic plasticity in the hippocampus of adult rats induced by stimulation of the perforant pathway. |
2021-11-11 |
2023-08-13 |
rat |
| Sara Chavoshinezhad, Mohammad Ismail Zibaii, Mir Hossein Seyed Nazari, Abdolaziz Ronaghi, Afsaneh Asgari Taei, Ahmad Ghorbani, Sareh Pandamooz, Mohammad Saied Salehi, Neda Valian, Fereshteh Motamedi, Abbas Haghparast, Leila Dargah. Optogenetic stimulation of entorhinal cortex reveals the implication of insulin signaling in adult rat's hippocampal neurogenesis. Progress in neuro-psychopharmacology & biological psychiatry. vol 111. 2021-11-11. PMID:33964323. |
the expression of synaptic plasticity and neurogenesis markers in the hippocampus were evaluated using molecular and histological approaches. |
2021-11-11 |
2023-08-13 |
rat |
| Sara Chavoshinezhad, Mohammad Ismail Zibaii, Mir Hossein Seyed Nazari, Abdolaziz Ronaghi, Afsaneh Asgari Taei, Ahmad Ghorbani, Sareh Pandamooz, Mohammad Saied Salehi, Neda Valian, Fereshteh Motamedi, Abbas Haghparast, Leila Dargah. Optogenetic stimulation of entorhinal cortex reveals the implication of insulin signaling in adult rat's hippocampal neurogenesis. Progress in neuro-psychopharmacology & biological psychiatry. vol 111. 2021-11-11. PMID:33964323. |
our results showed that optogenetic stimulation of the entorhinal cortex promotes hippocampal neurogenesis and synaptic plasticity concomitant with the increased levels of insulin mrna and its signaling markers, neurotrophic factors, and activation of mitochondrial biogenesis. |
2021-11-11 |
2023-08-13 |
rat |
| Maria Rosaria Tropea, Domenica D Li Puma, Marcello Melone, Walter Gulisano, Ottavio Arancio, Claudio Grassi, Fiorenzo Conti, Daniela Puzz. Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology. Progress in neurobiology. vol 206. 2021-11-11. PMID:34453977. |
we found that α7nachr deletion caused an impairment of hippocampal synaptic plasticity and memory at 12 months of age, paralleled by an increase of amyloid precursor protein expression and aβ levels. |
2021-11-11 |
2023-08-13 |
mouse |