| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lianwei Mu, Jiajia Cai, Boya Gu, Laikang Yu, Cui Li, Qing-Song Liu, Li Zha. Treadmill Exercise Prevents Decline in Spatial Learning and Memory in 3×Tg-AD Mice through Enhancement of Structural Synaptic Plasticity of the Hippocampus and Prefrontal Cortex. Cells. vol 11. issue 2. 2022-01-21. PMID:35053360. |
treadmill exercise prevents decline in spatial learning and memory in 3×tg-ad mice through enhancement of structural synaptic plasticity of the hippocampus and prefrontal cortex. |
2022-01-21 |
2023-08-13 |
mouse |
| Lianwei Mu, Jiajia Cai, Boya Gu, Laikang Yu, Cui Li, Qing-Song Liu, Li Zha. Treadmill Exercise Prevents Decline in Spatial Learning and Memory in 3×Tg-AD Mice through Enhancement of Structural Synaptic Plasticity of the Hippocampus and Prefrontal Cortex. Cells. vol 11. issue 2. 2022-01-21. PMID:35053360. |
to investigate potential mechanisms for the treadmill exercise-induced improvement of spatial learning and memory, we examined structural synaptic plasticity in the hippocampus and prefrontal cortex of six-month-old 3×tg-ad mice that had undergone 12 weeks of treadmill exercise. |
2022-01-21 |
2023-08-13 |
mouse |
| Tamara Stojanovic, David Velarde Gamez, Gabor Jorrid Schuld, Daniel Bormann, Maureen Cabatic, Pavel Uhrin, Gert Lubec, Francisco J Monj. Age-Dependent and Pathway-Specific Bimodal Action of Nicotine on Synaptic Plasticity in the Hippocampus of Mice Lacking the miR-132/212 Genes. Cells. vol 11. issue 2. 2022-01-21. PMID:35053378. |
age-dependent and pathway-specific bimodal action of nicotine on synaptic plasticity in the hippocampus of mice lacking the mir-132/212 genes. |
2022-01-21 |
2023-08-13 |
mouse |
| Brigitte Potier, Louison Lallemant, Sandrine Parrot, Aline Huguet-Lachon, Geneviève Gourdon, Patrick Dutar, Mário Gomes-Pereir. DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus. International journal of molecular sciences. vol 23. issue 2. 2022-01-21. PMID:35054778. |
dm1 transgenic mice exhibit abnormal neurotransmitter homeostasis and synaptic plasticity in association with rna foci and mis-splicing in the hippocampus. |
2022-01-21 |
2023-08-13 |
mouse |
| Xintao Wang, Bonan Tong, Rongji Hui, Congcong Hou, Zilu Zhang, Ludi Zhang, Bing Xie, Zhiyu Ni, Bin Cong, Chunling Ma, Di We. The Role of Hyperthermia in Methamphetamine-Induced Depression-Like Behaviors: Protective Effects of Coral Calcium Hydride. Frontiers in molecular neuroscience. vol 14. 2022-01-21. PMID:35058751. |
however, hat aggravated meth-induced damage of hippocampal synaptic plasticity, reaction to oxidative stress, and neuroinflammation. |
2022-01-21 |
2023-08-13 |
mouse |
| Xintao Wang, Bonan Tong, Rongji Hui, Congcong Hou, Zilu Zhang, Ludi Zhang, Bing Xie, Zhiyu Ni, Bin Cong, Chunling Ma, Di We. The Role of Hyperthermia in Methamphetamine-Induced Depression-Like Behaviors: Protective Effects of Coral Calcium Hydride. Frontiers in molecular neuroscience. vol 14. 2022-01-21. PMID:35058751. |
herein, we found that cch pretreatment significantly attenuated meth-induced hyperthermia, and administration of cch after meth exposure also inhibited meth-induced depression-like behaviors and reduced the hippocampal synaptic plasticity damage. |
2022-01-21 |
2023-08-13 |
mouse |
| Adam Krzystyniak, Malgorzata Wesierska, Gregory Petrazzo, Agnieszka Gadecka, Magdalena Dudkowska, Anna Bielak-Zmijewska, Grazyna Mosieniak, Izabela Figiel, Jakub Wlodarczyk, Ewa Sikor. Combination of dasatinib and quercetin improves cognitive abilities in aged male Wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone H3 methylation profile. Aging. vol 14. issue undefined. 2022-01-19. PMID:35042834. |
combination of dasatinib and quercetin improves cognitive abilities in aged male wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone h3 methylation profile. |
2022-01-19 |
2023-08-13 |
mouse |
| Cátia R Lopes, Inês M Amaral, Marlene F Pereira, João P Lopes, Daniela Madeira, Paula M Canas, Rodrigo A Cunha, Paula Agostinh. Impact of blunting astrocyte activity on hippocampal synaptic plasticity in a mouse model of early Alzheimer's disease based on amyloid-β peptide exposure. Journal of neurochemistry. 2022-01-19. PMID:35043392. |
impact of blunting astrocyte activity on hippocampal synaptic plasticity in a mouse model of early alzheimer's disease based on amyloid-β peptide exposure. |
2022-01-19 |
2023-08-13 |
mouse |
| Cátia R Lopes, Inês M Amaral, Marlene F Pereira, João P Lopes, Daniela Madeira, Paula M Canas, Rodrigo A Cunha, Paula Agostinh. Impact of blunting astrocyte activity on hippocampal synaptic plasticity in a mouse model of early Alzheimer's disease based on amyloid-β peptide exposure. Journal of neurochemistry. 2022-01-19. PMID:35043392. |
amyloid-β peptides (aβ) accumulate in the brain since early alzheimer's disease (ad) and dysregulate hippocampal synaptic plasticity, the neurophysiological basis of memory. |
2022-01-19 |
2023-08-13 |
mouse |
| Cátia R Lopes, Inês M Amaral, Marlene F Pereira, João P Lopes, Daniela Madeira, Paula M Canas, Rodrigo A Cunha, Paula Agostinh. Impact of blunting astrocyte activity on hippocampal synaptic plasticity in a mouse model of early Alzheimer's disease based on amyloid-β peptide exposure. Journal of neurochemistry. 2022-01-19. PMID:35043392. |
alterations in synaptic plasticity, namely in ltp, can be due to communication failures between astrocytes and neurons; however, little is known about astrocytes´ ability to control hippocampal ltd, particularly in ad-like conditions. |
2022-01-19 |
2023-08-13 |
mouse |
| Jingli Chen, Chang Liu, Mu Xu, Jiaxi Zhu, Zhongyuan Xi. Upregulation of miR-19b-3p exacerbates chronic stress-induced changes in synaptic plasticity and cognition by targeting Drebrin. Neuropharmacology. 2022-01-18. PMID:35041806. |
electrophysiological analysis revealed that inhibition of mir-19b-3p rescued the limited synaptic transmission and synaptic plasticity in hippocampal neurons. |
2022-01-18 |
2023-08-13 |
mouse |
| Andrea Mancini, Antonio de Iure, Barbara Piccon. Basic mechanisms of plasticity and learning. Handbook of clinical neurology. vol 184. 2022-01-17. PMID:35034736. |
in this chapter, we will summarize the mechanisms underlying the main forms of synaptic plasticity taking advantage of the studies performed in the hippocampus and in the nucleus striatum, key brain structures that play a crucial role in cognition. |
2022-01-17 |
2023-08-13 |
Not clear |
| Antonio Suppa, Francesco Asci, Andrea Guerr. Transcranial magnetic stimulation as a tool to induce and explore plasticity in humans. Handbook of clinical neurology. vol 184. 2022-01-17. PMID:35034759. |
synaptic plasticity can be explored experimentally in animals through various standardized protocols for eliciting long-term potentiation and long-term depression in hippocampal and cortical slices. |
2022-01-17 |
2023-08-13 |
human |
| Lin-Hui Ma, Jie Wan, Jing Yan, Ning Wang, Yan-Ping Liu, Hai-Bi Wang, Cheng-Hua Zhou, Yu-Qing W. Hippocampal SIRT1-Mediated Synaptic Plasticity and Glutamatergic Neuronal Excitability Are Involved in Prolonged Cognitive Dysfunction of Neonatal Rats Exposed to Propofol. Molecular neurobiology. 2022-01-16. PMID:35034265. |
hippocampal sirt1-mediated synaptic plasticity and glutamatergic neuronal excitability are involved in prolonged cognitive dysfunction of neonatal rats exposed to propofol. |
2022-01-16 |
2023-08-13 |
rat |
| Lin-Hui Ma, Jie Wan, Jing Yan, Ning Wang, Yan-Ping Liu, Hai-Bi Wang, Cheng-Hua Zhou, Yu-Qing W. Hippocampal SIRT1-Mediated Synaptic Plasticity and Glutamatergic Neuronal Excitability Are Involved in Prolonged Cognitive Dysfunction of Neonatal Rats Exposed to Propofol. Molecular neurobiology. 2022-01-16. PMID:35034265. |
in this study, we investigated the effects of repeated neonatal propofol exposure on hippocampal synaptic plasticity, neuronal excitability, and cognitive function. |
2022-01-16 |
2023-08-13 |
rat |
| Lin-Hui Ma, Jie Wan, Jing Yan, Ning Wang, Yan-Ping Liu, Hai-Bi Wang, Cheng-Hua Zhou, Yu-Qing W. Hippocampal SIRT1-Mediated Synaptic Plasticity and Glutamatergic Neuronal Excitability Are Involved in Prolonged Cognitive Dysfunction of Neonatal Rats Exposed to Propofol. Molecular neurobiology. 2022-01-16. PMID:35034265. |
repeated neonatal propofol exposure reduced sirt1 expression, suppressed synaptic plasticity, decreased glutamatergic neuron excitability in the hippocampus, and damaged learning and memory abilities. |
2022-01-16 |
2023-08-13 |
rat |
| Min Hee Park, Kang Ho Park, Byung Jo Choi, Wan Hui Han, Hee Ji Yoon, Hye Yoon Jung, Jihoon Lee, Im-Sook Song, Dong Yu Lim, Min-Koo Choi, Yang-Ha Lee, Cheol-Min Park, Ming Wang, Jihoon Jo, Hee-Jin Kim, Seung Hyun Kim, Edward H Schuchman, Hee Kyung Jin, Jae-Sung Ba. Discovery of a dual-action small molecule that improves neuropathological features of Alzheimer's disease mice. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 3. 2022-01-14. PMID:35027452. |
this dual role of kari 201 in neurons efficiently rescued neuropathological features in ad mice, including amyloid beta deposition, autophagy dysfunction, neuroinflammation, synaptic loss, and decreased hippocampal neurogenesis and synaptic plasticity, leading to an improvement in memory function. |
2022-01-14 |
2023-08-13 |
mouse |
| Alessandro Virtuoso, Pernille Tveden-Nyborg, Anne Marie Voigt Schou-Pedersen, Jens Lykkesfeldt, Heidi Kaastrup Müller, Betina Elfving, Dorte Bratbo Sørense. A Long-Term Energy-Rich Diet Increases Prefrontal BDNF in Sprague-Dawley Rats. Nutrients. vol 14. issue 1. 2022-01-11. PMID:35011001. |
however, the highly palatable nature of caf may counteract a negative effect of chronic stress on anticipatory behavior and synaptic plasticity in the hippocampus, hence represent a confounding factor (e.g., when evaluating functional effects on the brain). |
2022-01-11 |
2023-08-13 |
human |
| Nan Lin, Xiao-Dong Pan, Ai-Qin Chen, Yuan-Gui Zhu, Ming Wu, Jing Zhang, Xiao-Chun Che. Corrigendum to "Tripchlorolide improves age-associated cognitive deficits by reversing hippocampal synaptic plasticity impairment and NMDA receptor dysfunction in SAMP8 mice" [Behav. Brain Res. 258 (2014) 8-18]. Behavioural brain research. vol 421. 2022-01-10. PMID:35007960. |
corrigendum to "tripchlorolide improves age-associated cognitive deficits by reversing hippocampal synaptic plasticity impairment and nmda receptor dysfunction in samp8 mice" [behav. |
2022-01-10 |
2023-08-13 |
mouse |
| Kang Wang, Fuhua Xu, James Maylie, Jing X. Anti-Müllerian Hormone Regulation of Synaptic Transmission in the Hippocampus Requires MAPK Signaling and Kv4.2 Potassium Channel Activity. Frontiers in neuroscience. vol 15. 2022-01-03. PMID:34975379. |
we recently reported that amh and amh-specific receptor anti-müllerian hormone receptor 2 (amhr2) are expressed in the hippocampus, and exogenous amh protein rapidly increased synaptic transmission and long-term synaptic plasticity at the ca3-ca1 synapses. |
2022-01-03 |
2023-08-13 |
mouse |