| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vishaal Rajani, Aida Maziar, Kwun Nok Mimi Man, Johannes W Hell, Qi Yua. Age-Dependent Contributions of NMDA Receptors and L-Type Calcium Channels to Long-Term Depression in the Piriform Cortex. International journal of molecular sciences. vol 22. issue 24. 2021-12-24. PMID:34948347. |
in the hippocampus, the contributions of n-methyl-d-aspartate receptors (nmdars) and l-type calcium channels (ltccs) to neuronal transmission and synaptic plasticity change with aging, underlying calcium dysregulation and cognitive dysfunction. |
2021-12-24 |
2023-08-13 |
rat |
| Vishaal Rajani, Aida Maziar, Kwun Nok Mimi Man, Johannes W Hell, Qi Yua. Age-Dependent Contributions of NMDA Receptors and L-Type Calcium Channels to Long-Term Depression in the Piriform Cortex. International journal of molecular sciences. vol 22. issue 24. 2021-12-24. PMID:34948347. |
the piriform cortex (pc) plays a significant role in odor associative memories, and like the hippocampus, exhibits forms of long-term synaptic plasticity. |
2021-12-24 |
2023-08-13 |
rat |
| Sara L Paulo, Catarina Miranda-Lourenço, Rita F Belo, Rui S Rodrigues, João Fonseca-Gomes, Sara R Tanqueiro, Vera Geraldes, Isabel Rocha, Ana M Sebastião, Sara Xapelli, Maria J Diógene. High Caloric Diet Induces Memory Impairment and Disrupts Synaptic Plasticity in Aged Rats. Current issues in molecular biology. vol 43. issue 3. 2021-12-23. PMID:34940136. |
ex vivo synaptic plasticity recorded from hippocampal slices from hcd-fed aged rats revealed a reduction in the magnitude of long-term potentiation, accompanied by a decrease in the levels of the brain-derived neurotrophic factor receptors trkb full-length (trkb-fl). |
2021-12-23 |
2023-08-13 |
rat |
| Ida Cariati, Roberto Bonanni, Gabriele Pallone, Manuel Scimeca, Claudio Frank, Virginia Tancredi, Giovanna D'Arcangel. Hippocampal Adaptations to Continuous Aerobic Training: A Functional and Ultrastructural Evaluation in a Young Murine Model. Journal of functional morphology and kinesiology. vol 6. issue 4. 2021-12-23. PMID:34940510. |
our results showed that an aerobic training protocol, well designed in terms of speed and speed variation, significantly contributes to improving synaptic plasticity and hippocampal ultrastructure, optimizing its benefits in the brain. |
2021-12-23 |
2023-08-13 |
mouse |
| Mahesh Shivarama Shetty, Laurence Ris, Roland F R Schindler, Keiko Mizuno, Laura Fedele, Karl Peter Giese, Thomas Brand, Ted Abe. Mice Lacking the cAMP Effector Protein POPDC1 Show Enhanced Hippocampal Synaptic Plasticity. Cerebral cortex (New York, N.Y. : 1991). 2021-12-22. PMID:34937090. |
mice lacking the camp effector protein popdc1 show enhanced hippocampal synaptic plasticity. |
2021-12-22 |
2023-08-13 |
mouse |
| Mahesh Shivarama Shetty, Laurence Ris, Roland F R Schindler, Keiko Mizuno, Laura Fedele, Karl Peter Giese, Thomas Brand, Ted Abe. Mice Lacking the cAMP Effector Protein POPDC1 Show Enhanced Hippocampal Synaptic Plasticity. Cerebral cortex (New York, N.Y. : 1991). 2021-12-22. PMID:34937090. |
in this study, we examine the role of popeye domain-containing protein 1 (popdc1) (or blood vessel epicardial substance (bves)), a camp effector protein, in modulating hippocampal synaptic plasticity. |
2021-12-22 |
2023-08-13 |
mouse |
| Mahesh Shivarama Shetty, Laurence Ris, Roland F R Schindler, Keiko Mizuno, Laura Fedele, Karl Peter Giese, Thomas Brand, Ted Abe. Mice Lacking the cAMP Effector Protein POPDC1 Show Enhanced Hippocampal Synaptic Plasticity. Cerebral cortex (New York, N.Y. : 1991). 2021-12-22. PMID:34937090. |
overall, these findings reveal popdc1 as a novel negative regulator of hippocampal synaptic plasticity and, together with recent evidence for its interaction with phosphodiesterases (pdes), suggest that popdc1 is involved in modulating activity-dependent local camp-pka-pde signaling. |
2021-12-22 |
2023-08-13 |
mouse |
| Mark St Pierre, Neetika Rastogi, Ashley Brown, Pritika Parmar, Charles Lechner, Camille Fung, Raul Chavez-Valde. Intrauterine growth restriction disrupts the postnatal critical period of synaptic plasticity in the mouse dorsal hippocampus in a model of hypertensive disease of pregnancy. Developmental neuroscience. 2021-12-21. PMID:34933306. |
intrauterine growth restriction disrupts the postnatal critical period of synaptic plasticity in the mouse dorsal hippocampus in a model of hypertensive disease of pregnancy. |
2021-12-21 |
2023-08-13 |
mouse |
| Mark St Pierre, Neetika Rastogi, Ashley Brown, Pritika Parmar, Charles Lechner, Camille Fung, Raul Chavez-Valde. Intrauterine growth restriction disrupts the postnatal critical period of synaptic plasticity in the mouse dorsal hippocampus in a model of hypertensive disease of pregnancy. Developmental neuroscience. 2021-12-21. PMID:34933306. |
because disturbance of hippocampal critical period (cpd) of synaptic plasticity leads to impairments similar to those described in iugr human offspring, we hypothesized that iugr would perturb the cpd of synaptic plasticity in the mouse hippocampus in our model. |
2021-12-21 |
2023-08-13 |
mouse |
| Prachi Ojha, Subhajit Pal, Samarjit Bhattacharyy. Regulation of metabotropic glutamate receptor internalization and synaptic AMPA receptor endocytosis by the post-synaptic protein Norbin. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2021-12-15. PMID:34907024. |
finally, we demonstrate an important mechanism by which norbin regulates mglur-mediated ampar endocytosis in hippocampal neurons, a cellular correlate for mglur-dependent synaptic plasticity. |
2021-12-15 |
2023-08-13 |
mouse |
| Waleska Maria Almeida Barros, Matheus Santos de Sousa Fernandes, Roberta Karlize Pereira Silva, Karollainy Gomes da Silva, Ana Patricia da Silva Souza, Mariluce Rodrigues Marques Silva, Ana Beatriz Januario da Silva, Gabriela Carvalho Jurema Santos, Maria Eduarda Rodrigues Alves Dos Santos, Taciane Silva do Carmo, Sandra Lopes de Souza, Viviane de Oliveira Nogueira Souz. Does the enriched environment alter memory capacity in malnourished rats by modulating BDNF expression? Journal of applied biomedicine. vol 19. issue 3. 2021-12-15. PMID:34907761. |
thereby, evidence from the scientific literature suggests that the mechanisms of synaptic plasticity in the hippocampus of adult animals are influenced by malnutrition and ee, and these alterations may involve the participation of bdnf as a key regulator in memory processes in the adult animal hippocampus. |
2021-12-15 |
2023-08-13 |
rat |
| Livine Craeghs, Zsuzsanna Callaerts-Vegh, Mieke Verslegers, Ann Van der Jeugd, Kristof Govaerts, Tom Dresselaers, Elise Wogensen, Tine Verreet, Lieve Moons, Mohammed A Benotmane, Uwe Himmelreich, Rudi D'Hoog. Prenatal Radiation Exposure Leads to Higher-Order Telencephalic Dysfunctions in Adult Mice That Coincide with Reduced Synaptic Plasticity and Cerebral Hypersynchrony. Cerebral cortex (New York, N.Y. : 1991). 2021-12-13. PMID:34902856. |
electrophysiological examination indicated impaired hippocampal synaptic plasticity. |
2021-12-13 |
2023-08-13 |
mouse |
| Alejandra Arias-Cavieres, Ateh Fonteh, Carolina I Castro-Rivera, Alfredo J Garci. Intermittent Hypoxia causes targeted disruption to NMDA receptor dependent synaptic plasticity in area CA1 of the hippocampus. Experimental neurology. vol 344. 2021-12-12. PMID:34256046. |
intermittent hypoxia causes targeted disruption to nmda receptor dependent synaptic plasticity in area ca1 of the hippocampus. |
2021-12-12 |
2023-08-13 |
mouse |
| Yukitoshi Izumi, Anil G Cashikar, Kathiresan Krishnan, Steven M Paul, Douglas F Covey, Steven J Mennerick, Charles F Zorumsk. A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 49. 2021-12-12. PMID:34725187. |
here, we examined the effects of lipopolysaccharide (lps), an activator of innate immunity, on 25hc production in microglia, and the effects of lps and 25hc on ca1 hippocampal synaptic plasticity and learning. |
2021-12-12 |
2023-08-13 |
Not clear |
| Yesenia Castillo-Ocampo, María Colón, Anixa Hernández, Pablo Lopez, Yamil Gerena, James T Porte. Plasticity of GluN1 at Ventral Hippocampal Synapses in the Infralimbic Cortex. Frontiers in synaptic neuroscience. vol 13. 2021-12-11. PMID:34335223. |
although the infralimbic cortex (il) is not thought to play a role in fear acquisition, recent experiments found evidence that synaptic plasticity is occurring at ventral hippocampal (vhpc) synapses in il during auditory fear acquisition as measured by changes in the |
2021-12-11 |
2023-08-13 |
Not clear |
| Qingyan Jiao, Xi Dong, Cunle Guo, Tongrui Wu, Feng Chen, Kai Zhang, Zengguang Ma, Yun Sun, Haiyan Cao, Chao Tian, Qi Hu, Nannan Liu, Yong Wang, Lijie Ji, Shutong Yang, Xinjun Zhang, Jie Li, Hui She. Effects of sleep deprivation of various durations on novelty-related object recognition memory and object location memory in mice. Behavioural brain research. vol 418. 2021-12-11. PMID:34624424. |
impairment of learning and memory function caused by lack of sleep is a common physiological phenomenon of which underlying changes in synaptic plasticity in the hippocampus are not well understood. |
2021-12-11 |
2023-08-13 |
mouse |
| Qingyan Jiao, Xi Dong, Cunle Guo, Tongrui Wu, Feng Chen, Kai Zhang, Zengguang Ma, Yun Sun, Haiyan Cao, Chao Tian, Qi Hu, Nannan Liu, Yong Wang, Lijie Ji, Shutong Yang, Xinjun Zhang, Jie Li, Hui She. Effects of sleep deprivation of various durations on novelty-related object recognition memory and object location memory in mice. Behavioural brain research. vol 418. 2021-12-11. PMID:34624424. |
the possible different effects of sleep deprivation (sd) lasting for various durations on learning and memory function and hippocampal synaptic plasticity are still not completely clear. |
2021-12-11 |
2023-08-13 |
mouse |
| Qingyan Jiao, Xi Dong, Cunle Guo, Tongrui Wu, Feng Chen, Kai Zhang, Zengguang Ma, Yun Sun, Haiyan Cao, Chao Tian, Qi Hu, Nannan Liu, Yong Wang, Lijie Ji, Shutong Yang, Xinjun Zhang, Jie Li, Hui She. Effects of sleep deprivation of various durations on novelty-related object recognition memory and object location memory in mice. Behavioural brain research. vol 418. 2021-12-11. PMID:34624424. |
then, hippocampal synaptic plasticity was evaluated after all behavioural experiments. |
2021-12-11 |
2023-08-13 |
mouse |
| Qingyan Jiao, Xi Dong, Cunle Guo, Tongrui Wu, Feng Chen, Kai Zhang, Zengguang Ma, Yun Sun, Haiyan Cao, Chao Tian, Qi Hu, Nannan Liu, Yong Wang, Lijie Ji, Shutong Yang, Xinjun Zhang, Jie Li, Hui She. Effects of sleep deprivation of various durations on novelty-related object recognition memory and object location memory in mice. Behavioural brain research. vol 418. 2021-12-11. PMID:34624424. |
specifically, 24 h rem sd improved novelty-related olm, accompanied by a significantly increased hippocampal synaptic plasticity, including gain of dendritic spines, increased expression of hippocampal glua1, and enhanced long-term potentiation (ltp), whereas 48 h rem sd showed no effect on olm or the hippocampal synaptic plasticity mentioned above; however, 72 h rem sd impaired novelty-related olm and weakened hippocampal synaptic plasticity, including serious loss of dendritic spines, decreased expression of hippocampal glua1, and significantly attenuated ltp. |
2021-12-11 |
2023-08-13 |
mouse |
| Qingyan Jiao, Xi Dong, Cunle Guo, Tongrui Wu, Feng Chen, Kai Zhang, Zengguang Ma, Yun Sun, Haiyan Cao, Chao Tian, Qi Hu, Nannan Liu, Yong Wang, Lijie Ji, Shutong Yang, Xinjun Zhang, Jie Li, Hui She. Effects of sleep deprivation of various durations on novelty-related object recognition memory and object location memory in mice. Behavioural brain research. vol 418. 2021-12-11. PMID:34624424. |
our results suggest that rem sd of various durations has different effects on both novelty-related olm and hippocampal synaptic plasticity. |
2021-12-11 |
2023-08-13 |
mouse |