| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hardy Hagena, Mirko Feldmann, Denise Manahan-Vaugha. Lifelong changes of neurotransmitter receptor expression and debilitation of hippocampal synaptic plasticity following early postnatal blindness. Scientific reports. vol 12. issue 1. 2022-06-01. PMID:35650390. |
here, we explored whether recovery from adaptive changes in the expression of plasticity-related neurotransmitter receptors and hippocampal synaptic plasticity occurs in the time-period of up to 12 months after onset of sensory loss. |
2022-06-01 |
2023-08-13 |
mouse |
| Hardy Hagena, Mirko Feldmann, Denise Manahan-Vaugha. Lifelong changes of neurotransmitter receptor expression and debilitation of hippocampal synaptic plasticity following early postnatal blindness. Scientific reports. vol 12. issue 1. 2022-06-01. PMID:35650390. |
hippocampal synaptic plasticity was persistently compromised in vivo. |
2022-06-01 |
2023-08-13 |
mouse |
| Hardy Hagena, Mirko Feldmann, Denise Manahan-Vaugha. Lifelong changes of neurotransmitter receptor expression and debilitation of hippocampal synaptic plasticity following early postnatal blindness. Scientific reports. vol 12. issue 1. 2022-06-01. PMID:35650390. |
a partial recovery of hippocampal synaptic plasticity emerges in advanced adulthood, however. |
2022-06-01 |
2023-08-13 |
mouse |
| Lisa Topolnik, Suhel Tambol. The role of inhibitory circuits in hippocampal memory processing. Nature reviews. Neuroscience. 2022-05-31. PMID:35637416. |
these studies highlight unique contributions of distinct interneuron types to the temporal binding of hippocampal ensembles, synaptic plasticity and the acquisition of spatial and contextual information. |
2022-05-31 |
2023-08-13 |
Not clear |
| Luca Franchini, Jennifer Stanic, Marta Barzasi, Elisa Zianni, Daniela Mauceri, Monica Diluca, Fabrizio Gardon. Rabphilin-3A Drives Structural Modifications of Dendritic Spines Induced by Long-Term Potentiation. Cells. vol 11. issue 10. 2022-05-28. PMID:35626653. |
overall, our results demonstrate a key role for rph3a in the modulation of structural synaptic plasticity at hippocampal synapses that correlates with its interactions with both nmdars and ampars. |
2022-05-28 |
2023-08-13 |
Not clear |
| Erin L Grafe, Mira M M Wade, Claire E Hodson, Jennifer D Thomas, Brian R Christi. Postnatal Choline Supplementation Rescues Deficits in Synaptic Plasticity Following Prenatal Ethanol Exposure. Nutrients. vol 14. issue 10. 2022-05-28. PMID:35631142. |
this study used an animal model to determine if choline supplementation could restore hippocampal synaptic plasticity that is normally impaired by prenatal alcohol. |
2022-05-28 |
2023-08-13 |
rat |
| Thomas M Sanderson, Liam T Ralph, Mascia Amici, Ai Na Ng, Bong-Kiun Kaang, Min Zhuo, Sang Jeong Kim, John Georgiou, Graham L Collingridg. Selective Recruitment of Presynaptic and Postsynaptic Forms of mGluR-LTD. Frontiers in synaptic neuroscience. vol 14. 2022-05-26. PMID:35615440. |
our results reveal an unexpected complexity to mglur-mediated synaptic plasticity in the hippocampus. |
2022-05-26 |
2023-08-13 |
Not clear |
| Allison M Burns, Mélissa Farinelli-Scharly, Sandrine Hugues-Ascery, Jose Vicente Sanchez-Mut, Giulia Santoni, Johannes Gräf. The HDAC inhibitor CI-994 acts as a molecular memory aid by facilitating synaptic and intracellular communication after learning. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 22. 2022-05-25. PMID:35613054. |
we found that combining hdacis with fear learning, but not either treatment alone, enhances synaptic plasticity as well as memory-promoting transcriptional signaling in the hippocampus, a brain area recruited by fear learning, but not in unrelated areas. |
2022-05-25 |
2023-08-13 |
Not clear |
| Sakthi Jothi Muthu, Ganesh Lakashmanan, Khayinmi Wungmarong Shimray, Kathiravan Kaliyappan, Sathya Bharathy Sathyanathan, Prakash Seppa. Testosterone Influence on Microtubule Associated Proteins and Spine Density in Hippocampus: Implications on Learning and Memory. Developmental neuroscience. 2022-05-24. PMID:35609517. |
androgen-depleted rat showed impaired synaptic plasticity in hippocampus associated with contracted microtubule dynamics. |
2022-05-24 |
2023-08-13 |
rat |
| Sakthi Jothi Muthu, Ganesh Lakashmanan, Khayinmi Wungmarong Shimray, Kathiravan Kaliyappan, Sathya Bharathy Sathyanathan, Prakash Seppa. Testosterone Influence on Microtubule Associated Proteins and Spine Density in Hippocampus: Implications on Learning and Memory. Developmental neuroscience. 2022-05-24. PMID:35609517. |
observations suggest that androgen regulates expression of neural tissue-specific maps and play a vital role in hippocampus synaptic plasticity, and a similar mechanism may underlie neurological disorders in aging and hypogonadal men. |
2022-05-24 |
2023-08-13 |
rat |
| Guoli Wang, Tianyue An, Cong Lei, Xiaofeng Zhu, Li Yang, Lianxue Zhang, Ronghua Zhan. Antidepressant-like effect of ginsenoside Rb1 on potentiating synaptic plasticity via the miR-134-mediated BDNF signaling pathway in a mouse model of chronic stress-induced depression. Journal of ginseng research. vol 46. issue 3. 2022-05-23. PMID:35600767. |
however, the underlying mechanism through which rb1 counteracts stress-induced aberrant hippocampal synaptic plasticity via bdnf-trkb signaling remains elusive. |
2022-05-23 |
2023-08-13 |
mouse |
| John J Maurer, Mathieu E Wimmer, Christopher A Turner, Rae J Herman, Yafang Zhang, Kael Ragnini, Julia Ferrante, Blake A Kimmey, Richard C Crist, R Christopher Pierce, Heath D Schmid. Paternal nicotine taking elicits heritable sex-specific phenotypes that are mediated by hippocampal Satb2. Molecular psychiatry. 2022-05-20. PMID:35595980. |
using an unbiased, genome-wide approach, we discovered that these phenotypes were associated with decreased expression of satb2, a transcription factor known to play important roles in synaptic plasticity and memory formation, in the hippocampus of nicotine-sired male offspring. |
2022-05-20 |
2023-08-13 |
Not clear |
| Alejandra Arias-Cavieres, Alfredo Garci. Postnatal age influences how Intermittent Hypoxia impacts hippocampal synaptic plasticity and NMDA receptor subunit expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35551929. |
postnatal age influences how intermittent hypoxia impacts hippocampal synaptic plasticity and nmda receptor subunit expression. |
2022-05-13 |
2023-08-13 |
mouse |
| Alejandra Arias-Cavieres, Alfredo Garci. Postnatal age influences how Intermittent Hypoxia impacts hippocampal synaptic plasticity and NMDA receptor subunit expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35551929. |
in contrast to the ih-mediated effects in the adult hippocampus, nih neither suppressed glun1 expression nor eliminated nmdar-dependent synaptic plasticity, but rather caused nmdar subunit remodeling by causing glun2a downregulation and glun2b upregulation. |
2022-05-13 |
2023-08-13 |
mouse |
| Kathleen E Murray, Whitney A Ratliff, Vedad Delic, Bruce A Citro. Regulatory Modulations and Dendritic Arborization in the Mouse Hippocampus Following Gulf War Toxicant Exposure. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555761. |
arc is predominantly expressed in cortical and hippocampal neurons and is critical for long-term potentiation (ltp) and stabilization of synaptic plasticity. |
2022-05-13 |
2023-08-13 |
mouse |
| Ashleigh K Polo, Brigitte Browe, Lin Piao, Willard W Sharp, Alfredo J Garci. Intermittent Hypoxia (IH) Impairs Hippocampal Oxygen Consumption and Neurophysiological Responses to Metabolic Challenge. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556367. |
previous work has shown that ih impairs many neurophysiological functions such as hippocampal adult neurogenesis and nmdar-dependent synaptic plasticity. |
2022-05-13 |
2023-08-13 |
Not clear |
| Viviana Villa, Giulia Montalto, Francesca Caudano, Ernesto Fedele, Roberta Ricciarell. Selective inhibition of phosphodiesterase 4D increases tau phosphorylation at Ser214 residue. BioFactors (Oxford, England). 2022-05-13. PMID:35561079. |
given that the neuronal camp/pka-activated cascade is involved in synaptic plasticity and memory, and that camp-enhancing strategies demonstrated promising therapeutic potential for the treatment of cognitive deficits, we investigated the impact of camp on ptau-s214 in n2a cells and rat hippocampal slices. |
2022-05-13 |
2023-08-13 |
rat |
| Huan Chen, Dan Qiao, Chang Wang, Bohan Zhang, Zhao Wang, Longmei Tang, Yibo Wang, Ran Zhang, Yizhou Zhang, Leigang Song, Hongchun Zuo, Fangzhen Guo, Xia Wang, Sha Li, Huixian Cu. Fragile X Mental Retardation Protein Mediates the Effects of Androgen on Hippocampal PSD95 Expression and Dendritic Spines Density/Morphology and Autism-Like Behaviors Through miR-125a. Frontiers in cellular neuroscience. vol 16. 2022-05-09. PMID:35530178. |
this study investigated whether fragile x mental retardation protein (fmrp), a selective rna-binding protein that regulates synaptic protein expression by interacting with mirnas, mediates the effects of androgens that play an important role in regulating the synaptic plasticity in the hippocampus. |
2022-05-09 |
2023-08-13 |
mouse |
| Correction to: "Maternal High-Fat Diet Multigenerationally Impairs Hippocampal Synaptic Plasticity and Memory in Male Rat Offspring". Endocrinology. vol 163. issue 6. 2022-05-07. PMID:35524974. |
correction to: "maternal high-fat diet multigenerationally impairs hippocampal synaptic plasticity and memory in male rat offspring". |
2022-05-07 |
2023-08-13 |
rat |
| Min Yan, Mingtao Xiong, Yongqiang Wu, Dong Lin, Peng Chen, Jiang Chen, Ziyang Liu, Hang Zhang, Dongyan Ren, Erkang Fei, Xinsheng Lai, Suqi Zou, Shunqi Wan. LRP4 is required for the olfactory association task in the piriform cortex. Cell & bioscience. vol 12. issue 1. 2022-05-07. PMID:35526070. |
low-density lipoprotein receptor-related protein 4 (lrp4) plays a critical role in the central nervous system (cns), including hippocampal synaptic plasticity, maintenance of excitatory synaptic transmission, fear regulation, as well as long-term potentiation (ltp). |
2022-05-07 |
2023-08-13 |
Not clear |