| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miyuki Takahashi, Takeru Nakabayashi, Naoki Mita, Xiaohua Jin, Yuta Aikawa, Kodai Sasamoto, Goichi Miyoshi, Mariko Miyata, Takafumi Inoue, Toshio Ohshim. Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons. Molecular brain. vol 15. issue 1. 2022-04-28. PMID:35484559. |
these results indicated that cdk5/p35 in excitatory neurons is important for the hippocampal synaptic plasticity and associative memory retention. |
2022-04-28 |
2023-08-13 |
mouse |
| Meishar Shahoha, Ronni Cohen, Yoav Ben-Simon, Uri Asher. cAMP-Dependent Synaptic Plasticity at the Hippocampal Mossy Fiber Terminal. Frontiers in synaptic neuroscience. vol 14. 2022-04-21. PMID:35444523. |
camp-dependent synaptic plasticity at the hippocampal mossy fiber terminal. |
2022-04-21 |
2023-08-13 |
Not clear |
| António M Carvalho da Silva, Cristina Lemos, Henrique B Silva, Ildete L Ferreira, Angelo R Tomé, A Cristina Rego, Rodrigo A Cunh. Simultaneous Alteration of the Circadian Variation of Memory, Hippocampal Synaptic Plasticity, and Metabolism in a Triple Transgenic Mouse Model of Alzheimer's Disease. Frontiers in aging neuroscience. vol 14. 2022-04-18. PMID:35431906. |
simultaneous alteration of the circadian variation of memory, hippocampal synaptic plasticity, and metabolism in a triple transgenic mouse model of alzheimer's disease. |
2022-04-18 |
2023-08-13 |
mouse |
| Krislei Scienza-Martin, Fernanda Nogueira Lotz, Querusche Klippel Zanona, Fabiana Santana-Kragelund, Ana Paula Crestani, Flávia Zacouteguy Boos, Maria Elisa Calcagnotto, Jorge Alberto Quillfeld. Memory consolidation depends on endogenous hippocampal levels of anandamide: CB1 and M4, but possibly not TRPV1 receptors mediate AM404 effects. Neuroscience. 2022-04-18. PMID:35436517. |
the endocannabinoid system is involved in the fine-tuning of local synaptic plasticity in the hippocampus during the initial steps of memory formation/transformation. |
2022-04-18 |
2023-08-13 |
rat |
| Maryam Naseh, Mahnaz Bayat, Somayeh Akbari, Jafar Vatanparast, Mohammad Shabani, Afshin Borhani Haghighi, Masoud Haghan. Neuroprotective effects of sodium valproate on hippocampal cell and volume, and cognitive function in a rat model of focal cerebral ischemia. Physiology & behavior. 2022-04-13. PMID:35417732. |
this study evaluated whether vpa treatment ameliorated the synaptic plasticity dysfunction, hippocampal neuronal loss, and spatial memory deficits induced by cerebral ischemia in the middle cerebral artery occlusion (mcao) model. |
2022-04-13 |
2023-08-13 |
rat |
| Maryam Naseh, Mahnaz Bayat, Somayeh Akbari, Jafar Vatanparast, Mohammad Shabani, Afshin Borhani Haghighi, Masoud Haghan. Neuroprotective effects of sodium valproate on hippocampal cell and volume, and cognitive function in a rat model of focal cerebral ischemia. Physiology & behavior. 2022-04-13. PMID:35417732. |
hippocampal synaptic plasticity in the ca1 area was recorded by field potential recording. |
2022-04-13 |
2023-08-13 |
rat |
| Risto Halonen, Liisa Kuula, Jari Lahti, Katri Räikkönen, Anu-Katriina Pesone. The association between overnight recognition accuracy and slow oscillation-spindle coupling is moderated by BDNF Val66Met. Behavioural brain research. 2022-04-11. PMID:35405173. |
brain-derived neurotrophic factor (bdnf) val66met and catechol-o-methyltransferase (comt) val158met are repeatedly reported to implicate the structure and function of prefrontal and hippocampal areas as well as molecular events promoting synaptic plasticity. |
2022-04-11 |
2023-08-13 |
Not clear |
| Di Liu, Feng Lv, Su Min, You Yang, Lihao Che. Inhibition of NLRP3 inflammasome-mediated neuroinflammation alleviates electroconvulsive shock-induced memory impairment via regulation of hippocampal synaptic plasticity in depressive rats. Behavioural brain research. 2022-04-07. PMID:35390431. |
inhibition of nlrp3 inflammasome-mediated neuroinflammation alleviates electroconvulsive shock-induced memory impairment via regulation of hippocampal synaptic plasticity in depressive rats. |
2022-04-07 |
2023-08-13 |
rat |
| Mengqi Ouyang, Qi Zhang, Jiahui Shu, Zhiqiang Wang, Jin Fan, Ke Yu, Lei Lei, Yuxia Li, Qingsong Wan. Capsaicin Ameliorates the Loosening of Mitochondria-Associated Endoplasmic Reticulum Membranes and Improves Cognitive Function in Rats With Chronic Cerebral Hypoperfusion. Frontiers in cellular neuroscience. vol 16. 2022-04-04. PMID:35370565. |
capsaicin, a specific agonist known to activated the transient receptor potential vanilloid type 1 (trpv1), is involved in hippocampal synaptic plasticity and memory, but the detailed mechanism is still unclear. |
2022-04-04 |
2023-08-13 |
rat |
| Yuan Wang, Yi-Kai Jin, Tie-Cheng Guo, Zhen-Rong Li, Bing-Yan Feng, Jin-Hong Han, Martin Vreugdenhil, Cheng-Biao L. Activation of Dopamine 4 Receptor Subtype Enhances Gamma Oscillations in Hippocampal Slices of Aged Mice. Frontiers in aging neuroscience. vol 14. 2022-04-04. PMID:35370600. |
recent studies indicate that activation of dopamine 4 receptor (dr4) enhanced hippocampal γ oscillation of young mice and fully recovered the impaired hippocampal synaptic plasticity of aged mice, we determined whether this receptor is involved in aging-related modulation of hippocampal γ oscillation. |
2022-04-04 |
2023-08-13 |
mouse |
| Xi Xiao, Hui Zhang, Wen Ning, Zhuo Yang, Yue Wang, Tao Zhan. Knockdown of FSTL1 inhibits microglia activation and alleviates depressive-like symptoms through modulating TLR4/MyD88/NF-κB pathway in CUMS mice. Experimental neurology. 2022-04-03. PMID:35367454. |
moreover, fstl1 knockdown reversed cums induced synaptic plasticity deficits in the pp-dg pathway of the hippocampus and increased the expression of synaptic associated proteins in the hippocampus of cums exposed mice. |
2022-04-03 |
2023-08-13 |
mouse |
| Chang Cao, Liangwei Wang, Jing Zhang, Zhanzhan Liu, Mingming Li, Shangfu Xie, Guang Chen, Xiang X. Neuroligin-1 plays an important role in methamphetamine-induced hippocampal synaptic plasticity. Toxicology letters. 2022-03-25. PMID:35331841. |
neuroligin-1 plays an important role in methamphetamine-induced hippocampal synaptic plasticity. |
2022-03-25 |
2023-08-13 |
mouse |
| Chang Cao, Liangwei Wang, Jing Zhang, Zhanzhan Liu, Mingming Li, Shangfu Xie, Guang Chen, Xiang X. Neuroligin-1 plays an important role in methamphetamine-induced hippocampal synaptic plasticity. Toxicology letters. 2022-03-25. PMID:35331841. |
therefore, our study provides evidence that nlg-1 is involved in meth-induced hippocampal synaptic plasticity and may be a potential target for the treatment of meth-induced neurotoxicity. |
2022-03-25 |
2023-08-13 |
mouse |
| Dana Lengel, Zoe L Romm, Anna L Bostwick, Jimmy W Huh, Nathaniel W Snyder, George Smith, Ramesh Raghupath. Glucocorticoid Receptor Overexpression in the Dorsal Hippocampus Attenuates Spatial Learning and Synaptic Plasticity Deficits Following Pediatric Traumatic Brain Injury. Journal of neurotrauma. 2022-03-16. PMID:35293260. |
glucocorticoid receptor overexpression in the dorsal hippocampus attenuates spatial learning and synaptic plasticity deficits following pediatric traumatic brain injury. |
2022-03-16 |
2023-08-13 |
human |
| Dana Lengel, Zoe L Romm, Anna L Bostwick, Jimmy W Huh, Nathaniel W Snyder, George Smith, Ramesh Raghupath. Glucocorticoid Receptor Overexpression in the Dorsal Hippocampus Attenuates Spatial Learning and Synaptic Plasticity Deficits Following Pediatric Traumatic Brain Injury. Journal of neurotrauma. 2022-03-16. PMID:35293260. |
in this study, the role of glucocorticoid receptor (gr) function in the dorsal hippocampus (dh) in hippocampal-dependent cognitive function and synaptic plasticity were assessed following injury to the 11-day-old rat. |
2022-03-16 |
2023-08-13 |
human |
| Jinxin Gu, Lixue Chen, Ran Sun, Jie-Li Wang, Juntao Wang, Yingjun Lin, Shuwen Lei, Yang Zhang, Dan Lv, Faqin Jiang, Yuru Deng, James P Collman, Lei F. Plasmalogens Eliminate Aging-Associated Synaptic Defects and Microglia-Mediated Neuroinflammation in Mice. Frontiers in molecular biosciences. vol 9. 2022-03-14. PMID:35281262. |
further rna-sequencing, immunoblotting and immunofluorescence analyses confirmed that plasmalogens remarkably enhanced both the synaptic plasticity and neurogenesis in aged murine hippocampus. |
2022-03-14 |
2023-08-13 |
mouse |
| Segewkal H Heruye, Ted J Warren, Joseph A Kostansek Iv, Samantha B Draves, Stephanie A Matthews, Peter J West, Kristina A Simeone, Timothy A Simeon. Ascorbic Acid Reduces Neurotransmission, Synaptic Plasticity, and Spontaneous Hippocampal Rhythms in In Vitro Slices. Nutrients. vol 14. issue 3. 2022-03-12. PMID:35276972. |
ascorbic acid reduces neurotransmission, synaptic plasticity, and spontaneous hippocampal rhythms in in vitro slices. |
2022-03-12 |
2023-08-13 |
mouse |
| Yee Song Chong, Lik-Wei Wong, Jessica Gaunt, Yan Jun Lee, Cai Shan Goh, Richard G M Morris, Toh Hean Ch'ng, Sreedharan Sajikuma. Distinct contributions of ventral CA1/amygdala co-activation to the induction and maintenance of synaptic plasticity. Cerebral cortex (New York, N.Y. : 1991). 2022-03-07. PMID:35253866. |
the amygdala is known to modulate hippocampal synaptic plasticity. |
2022-03-07 |
2023-08-13 |
Not clear |
| Yee Song Chong, Lik-Wei Wong, Jessica Gaunt, Yan Jun Lee, Cai Shan Goh, Richard G M Morris, Toh Hean Ch'ng, Sreedharan Sajikuma. Distinct contributions of ventral CA1/amygdala co-activation to the induction and maintenance of synaptic plasticity. Cerebral cortex (New York, N.Y. : 1991). 2022-03-07. PMID:35253866. |
one role could be an immediate effect of basolateral amygdala (bla) in priming synaptic plasticity in the hippocampus. |
2022-03-07 |
2023-08-13 |
Not clear |
| Maxence Cornille, Stéphanie Moriceau, Roman H Khonsari, Yann Heuzé, Léa Loisay, Valérie Boitez, Anne Morice, Eric Arnaud, Corinne Collet, Morad Bensidhoum, Nabil Kaci, Nathalie Boddaert, Giovanna Paternoster, Theresa Rauschendorfer, Sabine Werner, Suzanne L Mansour, Federico Di Rocco, Franck Oury, Laurence Legeai-Malle. FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model. The Journal of experimental medicine. vol 219. issue 4. 2022-03-07. PMID:35254402. |
surprisingly, fgfr3a385e/+ mice did not exhibit craniosynostosis but did show severe memory impairments, a structurally abnormal hippocampus, low activity-dependent synaptic plasticity, and overactivation of mapk/erk and akt signaling pathways in the hippocampus. |
2022-03-07 |
2023-08-13 |
mouse |