| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mengying Liu, Biyao Lian, Zhen Lan, Huan Sun, Yangang Zhao, Tao Sun, Zhaoyou Meng, Chengjun Zhao, Jiqiang Zhan. Transcriptomic Profile Identifies Hippocampal Sgk1 as the Key Mediator of Ovarian Estrogenic Regulation on Spatial Learning and Memory and Aβ Accumulation. Neurochemical research. 2022-08-01. PMID:35915371. |
previous studies have shown that ovarian estrogens are involved in the occurrence and pathology of alzheimer's disease (ad) through regulation on hippocampal synaptic plasticity and spatial memory; however, the underlying mechanisms have not yet been elucidated at the genomic scale. |
2022-08-01 |
2023-08-14 |
mouse |
| Yingying Zha, Yan Jin, Xinxing Wang, Lin Chen, Xulai Zhang, Ming Wan. Long-term maintenance of synaptic plasticity by Fullerenol Ameliorates lead-induced-impaired learning and memory in vivo. Journal of nanobiotechnology. vol 20. issue 1. 2022-07-31. PMID:35909130. |
furthermore, electrophysiology examinations indicated that this potential repair effect of fullerenol was mainly due to the long-term changes in hippocampal synaptic plasticity, with enhancement lasting for more than 2-3 h. |
2022-07-31 |
2023-08-14 |
rat |
| Xiaona Liu, Jing Wan. NMDA receptors mediate synaptic plasticity impairment of hippocampal neurons due to arsenic exposure. Neuroscience. 2022-07-29. PMID:35905926. |
nmda receptors mediate synaptic plasticity impairment of hippocampal neurons due to arsenic exposure. |
2022-07-29 |
2023-08-14 |
Not clear |
| Xiaona Liu, Jing Wan. NMDA receptors mediate synaptic plasticity impairment of hippocampal neurons due to arsenic exposure. Neuroscience. 2022-07-29. PMID:35905926. |
here, we provide an overview of the mechanisms that nmdars and their downstream signaling pathways mediate synaptic plasticity impairment due to arsenic exposure in hippocampal neurons, ways of arsenic exerting on nmdars, as well as the potential therapeutic targets except for water improvement. |
2022-07-29 |
2023-08-14 |
Not clear |
| Yeon Hee Yu, Seong-Wook Kim, Hyuna Im, Se Won Oh, Nam-Jun Cho, Samel Park, Dae-Kyoon Park, Duk-Soo Kim, Hyo-Wook Gi. Cognitive Sequelae and Hippocampal Dysfunction in Chronic Kidney Disease following 5/6 Nephrectomy. Brain sciences. vol 12. issue 7. 2022-07-27. PMID:35884712. |
in addition, vascular dementia-induced alterations in the structure and function of the hippocampus can lead to deficits in hippocampal synaptic plasticity and cognitive function. |
2022-07-27 |
2023-08-14 |
rat |
| Elena I Zakharova, Andrey T Proshin, Mikhail Y Monakov, Alexander M Dudchenk. Cholinergic Internal and Projection Systems of Hippocampus and Neocortex Critical for Early Spatial Memory Consolidation in Normal and Chronic Cerebral Hypoperfusion Conditions in Rats with Different Abilities to Consolidation: The Role of Cholinergic Interneurons of the Hippocampus. Biomedicines. vol 10. issue 7. 2022-07-27. PMID:35884837. |
we found: (1) quartile-dependent cholinergic composition of 2s1 function and dynamics of cholinergic synaptic plasticity under cerebral hypoperfusion; (2) cholinergic hippocampal interneurons are necessary for successful 2s1 consolidation; (3) cholinergic neocortical interneurons and projections can be critical for 2s1 consolidation in less learning rats. |
2022-07-27 |
2023-08-14 |
human |
| Yuru Du, Yun Shi, Xi Wang, Han Song, Xinhao Wang, Ying Hao, Ye Zhao, Xiangfei Guo, Mengxu Shi, Miao Gong, Li Song, Sheng Wang, Yuan Gao, Haishui Sh. Hippocampal Semaphorin 3B Improves Depression-like Behaviours in Mice by Upregulating Synaptic Plasticity and Inhibiting Neuronal Apoptosis. Journal of neurochemistry. 2022-07-27. PMID:35892177. |
hippocampal semaphorin 3b improves depression-like behaviours in mice by upregulating synaptic plasticity and inhibiting neuronal apoptosis. |
2022-07-27 |
2023-08-14 |
mouse |
| Marion S Mercier, Vincent Magloire, Jonathan H Cornford, Dimitri M Kullman. Long-term potentiation in neurogliaform interneurons modulates excitation-inhibition balance in the temporoammonic pathway. The Journal of physiology. 2022-07-25. PMID:35876215. |
electrogenic phenomena in distal dendrites of principal neurons in the hippocampus have a major role in gating synaptic plasticity at afferent synapses on proximal dendrites. |
2022-07-25 |
2023-08-14 |
Not clear |
| Sarah E Svirsky, Nicholas S Ranellone, Madison Parry, Erik Holets, Jeremy Henchir, Youming Li, Shaun W Carlson, C Edward Dixo. All-trans retinoic acid has limited therapeutic effects on cognition and hippocampal protein expression after controlled cortical impact. Neuroscience. 2022-07-25. PMID:35878718. |
retinoic acid (ra) signaling modulates expression of synaptic plasticity proteins and is involved in hippocampal learning and memory. |
2022-07-25 |
2023-08-14 |
rat |
| Sarah E Svirsky, Nicholas S Ranellone, Madison Parry, Erik Holets, Jeremy Henchir, Youming Li, Shaun W Carlson, C Edward Dixo. All-trans retinoic acid has limited therapeutic effects on cognition and hippocampal protein expression after controlled cortical impact. Neuroscience. 2022-07-25. PMID:35878718. |
this study conducted an atra dose response to determine its therapeutic effects on cognitive behaviors and expression of hippocampal markers of synaptic plasticity and ra signaling proteins after experimental tbi. |
2022-07-25 |
2023-08-14 |
rat |
| Sarah E Svirsky, Nicholas S Ranellone, Madison Parry, Erik Holets, Jeremy Henchir, Youming Li, Shaun W Carlson, C Edward Dixo. All-trans retinoic acid has limited therapeutic effects on cognition and hippocampal protein expression after controlled cortical impact. Neuroscience. 2022-07-25. PMID:35878718. |
hippocampal expression of synaptic plasticity proteins neurogranin (ng), and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor glua1 sub-unit, as well as ra signaling proteins stra6, adlh1a1, cyp26a1 and cyp26b1 were evaluated by western blot at 2-weeks post-injury. |
2022-07-25 |
2023-08-14 |
rat |
| Zi-Rong Li, De-Guo Liu, Sheng Xie, Yu-Hong Wang, Yuan-Shan Han, Chun-Yan Li, Man-Shu Zou, Hai-Xing Jian. Sleep deprivation leads to further impairment of hippocampal synaptic plasticity by suppressing melatonin secretion in the pineal gland of chronically unpredictable stress rats. European journal of pharmacology. 2022-07-25. PMID:35878808. |
sleep deprivation leads to further impairment of hippocampal synaptic plasticity by suppressing melatonin secretion in the pineal gland of chronically unpredictable stress rats. |
2022-07-25 |
2023-08-14 |
rat |
| Zi-Rong Li, De-Guo Liu, Sheng Xie, Yu-Hong Wang, Yuan-Shan Han, Chun-Yan Li, Man-Shu Zou, Hai-Xing Jian. Sleep deprivation leads to further impairment of hippocampal synaptic plasticity by suppressing melatonin secretion in the pineal gland of chronically unpredictable stress rats. European journal of pharmacology. 2022-07-25. PMID:35878808. |
although depression and insomnia impair hippocampal synaptic plasticity, the mechanism by which this happens remains a mystery. |
2022-07-25 |
2023-08-14 |
rat |
| Zi-Rong Li, De-Guo Liu, Sheng Xie, Yu-Hong Wang, Yuan-Shan Han, Chun-Yan Li, Man-Shu Zou, Hai-Xing Jian. Sleep deprivation leads to further impairment of hippocampal synaptic plasticity by suppressing melatonin secretion in the pineal gland of chronically unpredictable stress rats. European journal of pharmacology. 2022-07-25. PMID:35878808. |
this study aimed to investigate the pathogenesis of insomnia comorbidity in depression and the regulatory effect of venlafaxine combined with melatonin on hippocampal synaptic plasticity in chronic unpredictable mild stress (cums) with sleep deprivation (sd) rats. |
2022-07-25 |
2023-08-14 |
rat |
| Zi-Rong Li, De-Guo Liu, Sheng Xie, Yu-Hong Wang, Yuan-Shan Han, Chun-Yan Li, Man-Shu Zou, Hai-Xing Jian. Sleep deprivation leads to further impairment of hippocampal synaptic plasticity by suppressing melatonin secretion in the pineal gland of chronically unpredictable stress rats. European journal of pharmacology. 2022-07-25. PMID:35878808. |
interestingly, venlafaxine + melatonin reversed these events by promoting hippocampal synaptic plasticity by regulating melatonin secretion from the pineal gland. |
2022-07-25 |
2023-08-14 |
rat |
| Zi-Rong Li, De-Guo Liu, Sheng Xie, Yu-Hong Wang, Yuan-Shan Han, Chun-Yan Li, Man-Shu Zou, Hai-Xing Jian. Sleep deprivation leads to further impairment of hippocampal synaptic plasticity by suppressing melatonin secretion in the pineal gland of chronically unpredictable stress rats. European journal of pharmacology. 2022-07-25. PMID:35878808. |
overall, the results of this study suggest that the pathophysiology of depressive insomnia comorbidity is mediated by impaired pineal melatonin secretion and impaired hippocampal synaptic plasticity. |
2022-07-25 |
2023-08-14 |
rat |
| Charlotte Tacke, Peter S DiStefano, Ronald M Lindsay, Kristin Metzdorf, Marta Zagrebelsky, Martin Kort. Actions of the TrkB Agonist Antibody ZEB85 in Regulating the Architecture and Synaptic Plasticity in Hippocampal Neurons. Frontiers in molecular neuroscience. vol 15. 2022-07-18. PMID:35845610. |
actions of the trkb agonist antibody zeb85 in regulating the architecture and synaptic plasticity in hippocampal neurons. |
2022-07-18 |
2023-08-14 |
Not clear |
| Tianhai Wang, Guiping Xu, Xue Zhang, Yanghao Ren, Tianyu Yang, Cheng Xiao, Chunyi Zho. Malfunction of astrocyte and cholinergic inputs is involved in postoperative impairment of hippocampal synaptic plasticity and cognitive function. Neuropharmacology. 2022-07-14. PMID:35835213. |
malfunction of astrocyte and cholinergic inputs is involved in postoperative impairment of hippocampal synaptic plasticity and cognitive function. |
2022-07-14 |
2023-08-14 |
mouse |
| Huan Chen, Dan Qiao, Yao Si, Zhen He, Bohan Zhang, Chang Wang, Yizhou Zhang, Xuelin Wang, Yichun Shi, Chengran Cui, Huixian Cui, Sha L. Effects of membrane androgen receptor binding on synaptic plasticity in primary hippocampal neurons. Molecular and cellular endocrinology. 2022-07-08. PMID:35803447. |
effects of membrane androgen receptor binding on synaptic plasticity in primary hippocampal neurons. |
2022-07-08 |
2023-08-14 |
mouse |
| Huan Chen, Dan Qiao, Yao Si, Zhen He, Bohan Zhang, Chang Wang, Yizhou Zhang, Xuelin Wang, Yichun Shi, Chengran Cui, Huixian Cui, Sha L. Effects of membrane androgen receptor binding on synaptic plasticity in primary hippocampal neurons. Molecular and cellular endocrinology. 2022-07-08. PMID:35803447. |
androgens play an important role in the regulation of hippocampal synaptic plasticity. |
2022-07-08 |
2023-08-14 |
mouse |